Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity

scientific article published on January 2007

Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1022725353
P356DOI10.1186/GB-2007-8-6-R122
P2888exact matchhttps://scigraph.springernature.com/pub.10.1186/gb-2007-8-6-r122
P932PMC publication ID2394766
P698PubMed publication ID17592649
P5875ResearchGate publication ID6244126

P50authorWindy A. BoydQ50768775
P2093author name stringJonathan H Freedman
Yuxia Cui
Sandra J McBride
Scott Alper
P2860cites workCytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
Cluster analysis and display of genome-wide expression patternsQ24644463
GoMiner: a resource for biological interpretation of genomic and proteomic dataQ24796534
Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functionsQ24803805
Statistical implications of pooling RNA samples for microarray experimentsQ24807222
Genomic and proteomic profiling of responses to toxic metals in human lung cellsQ24814797
Systematic functional analysis of the Caenorhabditis elegans genome using RNAiQ27860839
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegansQ27860971
TreeView: an application to display phylogenetic trees on personal computersQ27861074
A new pathway for heavy metal detoxification in animals. Phytochelatin synthase is required for cadmium tolerance in Caenorhabditis elegansQ28213578
A Caenorhabditis elegans MAP kinase kinase, MEK-1, is involved in stress responsesQ28344831
Effects of chronic exposure to cadmium on renal cytochrome P450-dependent monooxygenase system in ratsQ28572492
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi libraryQ28770084
C. elegans metallothioneins: new insights into the phenotypic effects of cadmium toxicosis.Q50794751
Microarray analysis of changes in bone cell gene expression early after cadmium gavage in miceQ57307987
Cadmium teratogenicity and its relationship with metallothionein gene expression in midgestation mouse embryosQ68569866
Teratogenicity of ionic cadmium in the Wistar ratQ69113261
Beryllium, cadmium, mercury, and exposures in the glass manufacturing industry. Working Group views and expert opinions, Lyon, 9-16 February 1993Q72038844
Induction of metallothionein in rat liver by cadmium chloride: probable mechanism of actionQ72527313
Metallothionein-null mice are more susceptible than wild-type mice to chronic CdCl(2)-induced bone injuryQ73930167
Effects of cadmium on metallothionein-I and metallothionein-II mRNA expression in rat ventral, lateral, and dorsal prostatic lobes: quantification by competitive RT-PCRQ77771702
A map of the interactome network of the metazoan C. elegansQ29547482
Functional genomic analysis of C. elegans chromosome I by systematic RNA interferenceQ29547812
Genome-wide RNAi screening in Caenorhabditis elegansQ29617900
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegansQ29618013
Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAiQ29618443
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome IIIQ29618444
KEGG-based pathway visualization tool for complex omics dataQ31015576
Evaluation of cadmium-induced transcriptome alterations by three color cDNA labeling microarray analysis on a T-cell lineQ31101567
Cadmium-induced gene expression changes in the mouse embryo, and the influence of pretreatment with zincQ33250292
Development of the GENIPOL European flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose.Q33264360
Metallothionein: an intracellular protein to protect against cadmium toxicityQ33636682
Inducible antibacterial defense system in C. elegansQ33960851
KEL-8 is a substrate receptor for CUL3-dependent ubiquitin ligase that regulates synaptic glutamate receptor turnoverQ34407303
A conserved role for a GATA transcription factor in regulating epithelial innate immune responsesQ35080455
Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zincQ35128011
DNA microarray analysis of altered gene expression in cadmium-exposed human cellsQ35607967
Responses to infection and possible recognition strategies in the innate immune system of Caenorhabditis elegans.Q35796495
A new pathway for vacuolar cadmium sequestration in Saccharomyces cerevisiae: YCF1-catalyzed transport of bis(glutathionato)cadmiumQ35898807
Techniques for analysis, sorting, and dispensing of C. elegans on the COPAS flow-sorting systemQ36599667
Use of cDNA subtraction and RNA interference screens in combination reveals genes required for germ-line development in Caenorhabditis elegansQ37111234
Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins.Q37285144
Regulation of metallothionein gene transcription. Identification of upstream regulatory elements and transcription factors responsible for cell-specific expression of the metallothionein genes from Caenorhabditis elegansQ38319731
Assessment of stress-related gene expression in the heavy metal-exposed nematode Caenorhabditis elegans: a potential biomarker for metal-induced toxicity monitoring and environmental risk assessmentQ39774020
The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress responseQ40561456
Roles of JNK, p38 and ERK mitogen-activated protein kinases in the growth inhibition and apoptosis induced by cadmiumQ40870782
Disruption of the intracellular sulfhydryl homeostasis by cadmium-induced oxidative stress leads to protein thiolation and ubiquitination in neuronal cellsQ41040434
Cadmium-regulated genes from the nematode Caenorhabditis elegans. Identification and cloning of new cadmium-responsive genes by differential displayQ42538168
Developmental toxicity of cadmium in mice. I. Embryotoxic effectsQ43418565
Influence of cadmium and zinc on the mice resistance to Listeria monocytogenes infectionQ43525808
Tissue-specific expression of two metallothionein genes in common carp during cadmium exposure and temperature shockQ43545652
Bioassay of cadmium using a DNA microarray: genome-wide expression patterns of Saccharomyces cerevisiae response to cadmiumQ43763602
Transient induction of metallothionein isoform 3 (MT-3), c-fos, c-jun and c-myc in human proximal tubule cells exposed to cadmiumQ43818834
DNA microarray analysis of human gene expression induced by a non-lethal dose of cadmiumQ44027808
Molecular characterization of a novel, cadmium-inducible gene from the nematode Caenorhabditis elegans. A new gene that contributes to the resistance to cadmium toxicityQ44110001
Genome-wide prediction of C. elegans genetic interactionsQ44214338
The effect of cadmium on the immune behaviour of guinea pigs with experimental ascariasisQ44526416
Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2.Q44812209
Cadmium at a non-toxic dose alters gene expression in mouse testesQ45121775
Developmental toxicity of cadmium in mice. II. Immunotoxic effectsQ45129091
Changes in Nuclear Receptor and Vitellogenin Gene Expression in Response to Steroids and Heavy Metal in Caenorhabditis elegansQ45377779
CeHMT-1, a putative phytochelatin transporter, is required for cadmium tolerance in Caenorhabditis elegansQ46445834
Interactive effects of cadmium and all-trans-retinoic acid on the induction of forelimb ectrodactyly in C57BL/6 miceQ46712401
Caenorhabditis elegans expresses a functional phytochelatin synthaseQ48355897
P4510describes a project that usesCytoscapeQ3699942
P433issue6
P921main subjectcadmiumQ1091
Caenorhabditis elegansQ91703
P304page(s)R122
P577publication date2007-01-01
P1433published inGenome BiologyQ5533480
P1476titleToxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity
P478volume8

Reverse relations

cites work (P2860)
Q35098053A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans
Q37335857Amide isosteres of oroidin: assessment of antibiofilm activity and C. elegans toxicity
Q37361030An intestinal microRNA modulates the homeostatic adaptation to chronic oxidative stress in C. elegans
Q46646955Antioxidant defense gene analysis in Brassica oleracea and Trifolium repens exposed to Cd and/or Pb.
Q38988525Atmospheric emission of nitric oxide and processes involved in its biogeochemical transformation in terrestrial environment
Q41680918Bioactivity of nanosilver in Caenorhabditis elegans: Effects of size, coat, and shape
Q35052913Biostimulation as an attractive technique to reduce phenanthrene toxicity for meiofauna and bacteria in lagoon sediment
Q45839958Biotreatment and bioassessment of heavy metal removal by sulphate reducing bacteria in fixed bed reactors
Q37173143Burkholderia pseudomallei suppresses Caenorhabditis elegans immunity by specific degradation of a GATA transcription factor
Q28750792Cadmium induces retinoic acid signaling by regulating retinoic acid metabolic gene expression
Q33939105Cadmium induces transcription independently of intracellular calcium mobilization
Q89621750Caenorhabditis elegans as a Biological Model for Multilevel Biomarker Analysis in Environmental Toxicology and Risk Assessment
Q90848690Caenorhabditis elegans as an emerging model system in environmental epigenetics
Q28748299Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivo
Q33463267Caenorhabditis elegans genomic response to soil bacteria predicts environment-specific genetic effects on life history traits
Q36512954Caenorhabditis elegans pgp-5 is involved in resistance to bacterial infection and heavy metal and its regulation requires TIR-1 and a p38 map kinase cascade
Q36927018Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology.
Q27678794Characterization of PUD-1 and PUD-2, Two Proteins Up-Regulated in a Long-Lived daf-2 Mutant
Q58761893Comparative metabolism of xenobiotic chemicals by cytochrome P450s in the nematode Caenorhabditis elegans
Q35154242Comparative toxicology of mercurials in Caenorhabditis elegans
Q90151666Comprehensive phenotyping and transcriptome profiling to study nanotoxicity in C. elegans
Q27324552Conserved nutrient sensor O-GlcNAc transferase is integral to C. elegans pathogen-specific immunity
Q35986214Contrasting invertebrate immune defense behaviors caused by a single gene, the Caenorhabditis elegans neuropeptide receptor gene npr-1
Q36667214Deletion of Phytochelatin Synthase Modulates the Metal Accumulation Pattern of Cadmium Exposed C. elegans
Q28535384Earthworms produce phytochelatins in response to arsenic
Q35302627Experimental studies with nematodes in ecotoxicology: an overview
Q33595247Functional toxicology: tools to advance the future of toxicity testing
Q34023900Gene expression modifications by temperature-toxicants interactions in Caenorhabditis elegans
Q30487296Gene expression profiling to characterize sediment toxicity--a pilot study using Caenorhabditis elegans whole genome microarrays
Q34956179Gene-environment and protein-degradation signatures characterize genomic and phenotypic diversity in wild Caenorhabditis elegans populations
Q35878191Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans
Q41811630Genome-wide gene expression analysis in response to organophosphorus pesticide chlorpyrifos and diazinon in C. elegans.
Q34872369Genomic analysis of stress response against arsenic in Caenorhabditis elegans
Q35841990Heme utilization in the Caenorhabditis elegans hypodermal cells is facilitated by heme-responsive gene-2.
Q34948860High concentration of vitamin E decreases thermosensation and thermotaxis learning and the underlying mechanisms in the nematode Caenorhabditis elegans
Q90007826Host Mucin Is Exploited by Pseudomonas aeruginosa To Provide Monosaccharides Required for a Successful Infection
Q33817242Identification of ATF-7 and the insulin signaling pathway in the regulation of metallothionein in C. elegans suggests roles in aging and reactive oxygen species
Q36634138Invertebrate models of dystonia
Q30494184Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans
Q35254761Longevity and stress in Caenorhabditis elegans
Q91800325Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans
Q64100385Meta-analysis suggests evidence of novel stress-related pathway components in Orsay virus - Caenorhabditis elegans viral model
Q38219984Metabolites and metals in Metazoa--what role do phytochelatins play in animals?
Q33891308Molecular characterization of numr-1 and numr-2: genes that increase both resistance to metal-induced stress and lifespan in Caenorhabditis elegans
Q36487684Molecular characterization of two homologs of the Caenorhabditis elegans cadmium-responsive gene cdr-1: cdr-4 and cdr-6
Q46309571Neurodegeneration Induced by Metals in Caenorhabditis elegans
Q92748110Oppia nitens C.L. Koch, 1836 (Acari: Oribatida): Current Status of Its Bionomics and Relevance as a Model Invertebrate in Soil Ecotoxicology
Q42777257PMK-1 p38 MAPK promotes cadmium stress resistance, the expression of SKN-1/Nrf and DAF-16 target genes, and protein biosynthesis in Caenorhabditis elegans
Q91932666RNA processing errors triggered by cadmium and integrator complex disruption are signals for environmental stress
Q33661396Regulation of Dauer formation by O-GlcNAcylation in Caenorhabditis elegans.
Q36194343Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons
Q36383664Role of MTL-1, MTL-2, and CDR-1 in mediating cadmium sensitivity in Caenorhabditis elegans
Q46322055Silencing of Repetitive DNA Is Controlled by a Member of an Unusual Caenorhabditis elegans Gene Family
Q37819497The Caenorhabiditis elegans model as a reliable tool in neurotoxicology
Q21145049The Mediator subunit MDT-15 confers metabolic adaptation to ingested material
Q36700088The nematode Caenorhabditis elegans as a tool to predict chemical activity on mammalian development and identify mechanisms influencing toxicological outcome
Q28480640The transcriptional response of Caenorhabditis elegans to Ivermectin exposure identifies novel genes involved in the response to reduced food intake
Q34601947The ubiquitin-fold modifier 1 (Ufm1) cascade of Caenorhabditis elegans
Q28485401Towards an understanding of the function of the phytochelatin synthase of Schistosoma mansoni
Q39139769Toxic potentiality of bio-oils, from biomass pyrolysis, in cultured cells and Caenorhabditis elegans
Q31168602Toxic-selenium and low-selenium transcriptomes in Caenorhabditis elegans: toxic selenium up-regulates oxidoreductase and down-regulates cuticle-associated genes
Q35845403Transcriptator: An Automated Computational Pipeline to Annotate Assembled Reads and Identify Non Coding RNA.
Q36213331Transcriptome Profiling Analysis of Wolf Spider Pardosa pseudoannulata (Araneae: Lycosidae) after Cadmium Exposure
Q42777538Transcriptomic profiling of chemical exposure reveals roles of Yap1 in protecting yeast cells from oxidative and other types of stresses.
Q35751448Transgenic nematodes as biosensors for metal stress in soil pore water samples
Q27322661ttm-1 encodes CDF transporters that excrete zinc from intestinal cells of C. elegans and act in a parallel negative feedback circuit that promotes homeostasis

Search more.