Gene-modified mesenchymal stem cells protect against radiation-induced lung injury

scientific article published on 13 November 2012

Gene-modified mesenchymal stem cells protect against radiation-induced lung injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MT.2012.183
P932PMC publication ID3594026
P698PubMed publication ID23299797
P5875ResearchGate publication ID234089433

P2093author name stringLu Gan
Xin Li
Jian Li
Lin Zhou
You Lu
Xianming Mo
Li Jia
Jie Lan
Lan Sun
Yongsheng Wang
Shurui Liu
Jianxin Xue
P2860cites workBone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease.Q37443277
Mesenchymal stem cell therapy for the treatment of chronic obstructive pulmonary disease.Q37729144
TGFbeta signalling: a complex web in cancer progressionQ37760038
Radiation Pulmonary Toxicity: From Mechanisms to ManagementQ37777878
Sarcoma derived from cultured mesenchymal stem cellsQ40220522
Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lungQ40233552
Prevention of radiation-induced pneumonitis by recombinant adenovirus-mediated transferring of soluble TGF-beta type II receptor geneQ40277998
Bone marrow-derived mesenchymal stem cells in repair of the injured lungQ41836696
Failure of bone marrow to reconstitute lung epitheliumQ42082666
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in miceQ42826405
Effects of lysophosphatidic acid and its receptors LPA⅓ on radiation pneumonitisQ42839221
Soluble TGFbeta type II receptor gene therapy ameliorates acute radiation-induced pulmonary injury in ratsQ45865268
Lack of a fusion requirement for development of bone marrow-derived epitheliaQ47252948
Alveolar epithelial cells: differentiation and lung injury.Q47653896
Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cellsQ47820046
Histopathologic amelioration of fibroproliferative change in rat irradiated lung using soluble transforming growth factor-beta (TGF-beta) receptor mediated by adenoviral vectorQ48000047
Injured microenvironment directly guides the differentiation of engrafted Flk-1(+) mesenchymal stem cell in lung.Q50673075
Elevation of plasma TGF-beta1 during radiation therapy predicts radiation-induced lung toxicity in patients with non-small-cell lung cancer: a combined analysis from Beijing and Michigan.Q51810354
Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice.Q53560785
Inhibition of the tumor necrosis factor-alpha pathway is radioprotective for the lungQ80889027
Antitransforming growth factor-beta antibody 1D11 ameliorates normal tissue damage caused by high-dose radiationQ83917127
Possibilities for the use of autologous mesenchymal stem cells in the therapy of radiation-induced lung injuriesQ84460685
New insights into the molecular pathology of radiation-induced pneumopathyQ84489783
Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cellQ28188430
Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1Q28757126
Identification of bronchioalveolar stem cells in normal lung and lung cancerQ29619267
Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 productionQ29619807
Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6Q29620590
Stem cells and cell therapies in lung biology and lung diseasesQ30486086
Bone marrow stem cells expressing keratinocyte growth factor via an inducible lentivirus protects against bleomycin-induced pulmonary fibrosisQ30942028
Hypoxia-inducible vascular endothelial growth factor-engineered mesenchymal stem cells prevent myocardial ischemic injuryQ34757237
Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironmentQ35087261
Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effectsQ35168236
Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapyQ35273018
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseasesQ35649473
Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in ratsQ35716182
Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injuryQ35841729
Role of the SDF-1/CXCR4 axis in the pathogenesis of lung injury and fibrosisQ36013707
Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation.Q36035053
Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension.Q36174893
Radiation pneumonitis and fibrosis: mechanisms underlying its pathogenesis and implications for future researchQ36663274
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapyQ37140126
Evidence that bone marrow cells do not contribute to the alveolar epitheliumQ37273936
Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lungQ37327475
Mesenchymal stem cell homing: the devil is in the detailsQ37407769
Radiation increases invasion of gene-modified mesenchymal stem cells into tumorsQ37408429
P433issue2
P921main subjectmesenchymal stem cellQ1922379
P304page(s)456-465
P577publication date2012-11-13
P1433published inMolecular TherapyQ15762400
P1476titleGene-modified mesenchymal stem cells protect against radiation-induced lung injury
P478volume21

Reverse relations

cites work (P2860)
Q36523196An Appreciation for the Rabbit Ladderlike Modeling of Radiation-induced Lung Injury with High-energy X-Ray
Q51057005Anti-fibrotic effects of bone morphogenetic protein-7-modified bone marrow mesenchymal stem cells on silica-induced pulmonary fibrosis.
Q43196038Azithromycin attenuates acute radiation-induced lung injury in mice
Q64253973CXCR4-Overexpressing Umbilical Cord Mesenchymal Stem Cells Enhance Protection against Radiation-Induced Lung Injury
Q64277124Concise Review: Therapeutic Potential of the Mesenchymal Stem Cell Derived Secretome and Extracellular Vesicles for Radiation-Induced Lung Injury: Progress and Hypotheses
Q64976524Cytokines and radiation-induced pulmonary injuries.
Q91788765Growth Factor Gene-Modified Mesenchymal Stem Cells in Tissue Regeneration
Q91737517Improved therapeutic potential of MSCs by genetic modification
Q49547836Mesenchymal stem cell-based therapy for radiation-induced lung injury
Q41175859Mesenchymal stem cell-conditioned medium prevents radiation-induced liver injury by inhibiting inflammation and protecting sinusoidal endothelial cells
Q54349782Mesenchymal stem cells are sensitive to treatment with kinase inhibitors and ionizing radiation.
Q47566394Mesenchymal stem cells: A double-edged sword in radiation-induced lung injury
Q28596834Mesenchymal stromal cell treatment prevents H9N2 avian influenza virus-induced acute lung injury in mice
Q35962631MiRNA-Related Genetic Variations Associated with Radiotherapy-Induced Toxicities in Patients with Locally Advanced Non-Small Cell Lung Cancer
Q37723306Optimal Dose and Timing of Umbilical Stem Cells Treatment in Pulmonary Arterial Hypertensive Rats
Q33765949Pulmonary emphysema is a risk factor for radiation pneumonitis in NSCLC patients with squamous cell carcinoma after thoracic radiation therapy
Q49955651Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab
Q37091912Resveratrol inhibits ionising irradiation-induced inflammation in MSCs by activating SIRT1 and limiting NLRP-3 inflammasome activation
Q90533433Reversal of bleomycin-induced rat pulmonary fibrosis by a xenograft of human umbilical mesenchymal stem cells from Wharton's jelly
Q50052350Stem Cell Therapies for the Resolution of Radiation Injury to the Brain
Q39548293TGF-β1 rs1982073 polymorphism contributes to radiation pneumonitis in lung cancer patients: a meta-analysis
Q38800242The Fatty Acid Amide Hydrolase Inhibitor URB937 Ameliorates Radiation-Induced Lung Injury in a Mouse Model.
Q35144202The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2.
Q35123851The association between TGF-β1 polymorphisms and radiation pneumonia in lung cancer patients treated with definitive radiotherapy: a meta-analysis

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