| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2008PNAS..105.7416C |
| P356 | DOI | 10.1073/PNAS.0801735105 |
| P932 | PMC publication ID | 2396690 |
| P698 | PubMed publication ID | 18492805 |
| P5875 | ResearchGate publication ID | 5357199 |
| P50 | author | Sriram Krishnaswamy | Q125130348 |
| P2093 | author name string | X Long Zheng | |
| Peter J Lenting | |||
| Wenjing Cao | |||
| Rodney M Camire | |||
| P2860 | cites work | The affinity and stoichiometry of binding of human factor VIII to von Willebrand factor | Q24318610 |
| Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura | Q24614077 | ||
| Calculation of protein extinction coefficients from amino acid sequence data | Q27861073 | ||
| Cofactor proteins in the assembly and expression of blood clotting enzyme complexes | Q28289123 | ||
| Association of the factor VIII light chain with von Willebrand factor | Q28630760 | ||
| Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension | Q29547330 | ||
| Deficiency of von Willebrand factor-cleaving protease in familial and acquired thrombotic thrombocytopenic purpura | Q33328325 | ||
| FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay | Q33365643 | ||
| Unusually large plasma factor VIII:von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura | Q33481821 | ||
| The life cycle of coagulation factor VIII in view of its structure and function | Q34481893 | ||
| The factor VIII/von Willebrand factor complex: basic and clinical issues. | Q35162604 | ||
| The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow | Q35990745 | ||
| Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress | Q36384693 | ||
| Binding of platelet glycoprotein Ibalpha to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13. | Q36986074 | ||
| Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies | Q40063048 | ||
| Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus | Q40506219 | ||
| Removal of B-domain sequences from factor V rather than specific proteolysis underlies the mechanism by which cofactor function is realized | Q40581702 | ||
| Cleavage of von Willebrand factor requires the spacer domain of the metalloprotease ADAMTS13. | Q40641838 | ||
| Isolation and characterization of thrombin-activated human factor VIII. | Q44003383 | ||
| Absence of compensatory platelet activation in patients with severe haemophilia, but evidence for a platelet collagen-activation defect | Q44252989 | ||
| Acquired von Willebrand factor deficiency during high-dose infusion of recombinant factor VIII. | Q45876959 | ||
| Zinc and calcium ions cooperatively modulate ADAMTS13 activity | Q46802670 | ||
| Activation of porcine factor VIII:C by thrombin and factor Xa. | Q52655588 | ||
| Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis. | Q55066473 | ||
| Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion. | Q55066475 | ||
| Human factor VIIIa subunit structure. Reconstruction of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit | Q67987635 | ||
| Characterization of the interaction between the A2 subunit and A1/A3-C1-C2 dimer in human factor VIIIa | Q68184742 | ||
| Thrombin | Q68236967 | ||
| von Willebrand factor is a cofactor for thrombin-catalyzed cleavage of the factor VIII light chain | Q68358970 | ||
| Stoichiometry of the porcine factor VIII-von Willebrand factor association | Q70370474 | ||
| Recombinant vWF type 2A mutants R834Q and R834W show a defect in mediating platelet adhesion to collagen, independent of enhanced sensitivity to a plasma protease | Q77997431 | ||
| P433 | issue | 21 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | proteolysis | Q33123 |
| Von Willebrand factor | Q412310 | ||
| identical protein binding | Q14762994 | ||
| P304 | page(s) | 7416-7421 | |
| P577 | publication date | 2008-05-20 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13. | |
| P478 | volume | 105 |
| Q33968288 | A conformation-sensitive monoclonal antibody against the A2 domain of von Willebrand factor reduces its proteolysis by ADAMTS13 |
| Q33427139 | A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria |
| Q33393728 | A shear-based assay for assessing plasma ADAMTS13 activity and inhibitors in patients with thrombotic thrombocytopenic purpura |
| Q28083264 | ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura |
| Q33408786 | ADAMTS13 content in plasma-derived factor VIII/von Willebrand factor concentrates |
| Q45858905 | Acquired autoimmune thrombotic thrombocytopenic purpura in a case of severe haemophilia A. |
| Q33519836 | An anticoagulant RNA aptamer that inhibits proteinase-cofactor interactions within prothrombinase |
| Q43186685 | Analysis of von Willebrand factor multimers by simultaneous high- and low-resolution vertical SDS-agarose gel electrophoresis and Cy5-labeled antibody high-sensitivity fluorescence detection |
| Q33403225 | Antigen and substrate withdrawal in the management of autoimmune thrombotic disorders. |
| Q88972732 | Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass |
| Q51026393 | Compromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII. |
| Q33381813 | Correction of ADAMTS13 deficiency by in utero gene transfer of lentiviral vector encoding ADAMTS13 genes |
| Q36093132 | Effects of HeartWare ventricular assist device on the von Willebrand factor: results of an academic Belgian center |
| Q33401369 | Endothelial cells and thrombotic microangiopathy |
| Q30504401 | Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis. |
| Q34684020 | Exploiting the kinetic interplay between GPIbα-VWF binding interfaces to regulate hemostasis and thrombosis |
| Q34121211 | Factor VIII and platelets synergistically accelerate cleavage of von Willebrand factor by ADAMTS13 under fluid shear stress |
| Q37279293 | Fluid shear induces conformation change in human blood protein von Willebrand factor in solution. |
| Q33399396 | Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura. |
| Q55241963 | In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process. |
| Q39905838 | Internal tension in a collapsed polymer under shear flow and the connection to enzymatic cleavage of von Willebrand factor |
| Q37317725 | Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site |
| Q36294654 | Light chain of factor VIII is sufficient for accelerating cleavage of von Willebrand factor by ADAMTS13 metalloprotease |
| Q33382999 | Mechanisms of microvascular thrombosis in thrombotic thrombocytopenic purpura |
| Q41512070 | Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels. |
| Q33381242 | Molecular basis of ADAMTS13 dysfunction in thrombotic thrombocytopenic purpura |
| Q37393329 | Multi-step binding of ADAMTS-13 to von Willebrand factor. |
| Q24620546 | Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura |
| Q37171410 | Normal cleavage of von Willebrand factor by ADAMTS-13 in the absence of factor VIII in patients with severe hemophilia A |
| Q89774847 | Novel mutations in ADAMTS13 CUB domains cause abnormal pre-mRNA splicing and defective secretion of ADAMTS13 |
| Q38128303 | On the versatility of von Willebrand factor |
| Q24614117 | Pathophysiology of thrombotic thrombocytopenic purpura |
| Q37077021 | Pharmacokinetics and safety of a novel recombinant human von Willebrand factor manufactured with a plasma-free method: a prospective clinical trial |
| Q38414457 | Plasma von Willebrand factor multimer quantitative analysis by in-gel immunostaining and infrared fluorescent imaging |
| Q35596768 | Probing ADAMTS13 substrate specificity using phage display |
| Q34078730 | Recombinant canine B-domain-deleted FVIII exhibits high specific activity and is safe in the canine hemophilia A model |
| Q33416588 | Rituximab and intermediate-purity plasma-derived factor VIII concentrate (Koate®) as adjuncts to therapeutic plasma exchange for thrombotic thrombocytopenic purpura in patients with an ADAMTS13 inhibitor |
| Q33419829 | Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition |
| Q30364288 | Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers. |
| Q37019574 | Structure-function and regulation of ADAMTS-13 protease |
| Q33392975 | Targeting von Willebrand factor and platelet glycoprotein Ib receptor |
| Q35579858 | Unconjugated bilirubin inhibits proteolytic cleavage of von Willebrand factor by ADAMTS13 protease. |
| Q37671400 | Update on von Willebrand factor multimers: focus on high-molecular-weight multimers and their role in hemostasis |
| Q33419324 | VWF excess and ADAMTS13 deficiency: a unifying pathomechanism linking inflammation to thrombosis in DIC, malaria, and TTP. |
| Q36010217 | von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesion |
| Q37370132 | von Willebrand factor cleaved from endothelial cells by ADAMTS13 remains ultralarge in size. |
| Q34310946 | von Willebrand factor self-association on platelet GpIbalpha under hydrodynamic shear: effect on shear-induced platelet activation |
| Q38047344 | von Willebrand factor: the old, the new and the unknown. |
Search more.