Compromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII.

scientific article published on 2 May 2013

Compromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1160/TH13-01-0053
P932PMC publication ID3813456
P698PubMed publication ID23636243

P50authorX. Long ZhengQ56808910
P2093author name stringChristopher G Skipwith
Sandra L Haberichter
Ashley Gehrand
P2860cites workvon Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndromeQ33504463
Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand FactorQ33998293
Factor VIII and platelets synergistically accelerate cleavage of von Willebrand factor by ADAMTS13 under fluid shear stressQ34121211
Exosite interactions contribute to tension-induced cleavage of von Willebrand factor by the antithrombotic ADAMTS13 metalloproteaseQ35193294
von Willebrand factor (VWF) propeptide binding to VWF D'D3 domain attenuates platelet activation and adhesionQ36010217
Light chain of factor VIII is sufficient for accelerating cleavage of von Willebrand factor by ADAMTS13 metalloproteaseQ36294654
Factor VIII accelerates proteolytic cleavage of von Willebrand factor by ADAMTS13.Q36677173
The genetic basis of von Willebrand diseaseQ37735428
An Arg760Cys mutation in the consensus sequence of the von Willebrand factor propeptide cleavage site is responsible for a new von Willebrand disease variantQ40694998
The defective interaction between von Willebrand factor and factor VIII in a patient with type 1 von Willebrand disease is caused by substitution of Arg19 and His54 in mature von Willebrand factor.Q41235952
Abnormal binding of factor VIII is linked with the substitution of glutamine for arginine 91 in von Willebrand factor in a variant form of von Willebrand diseaseQ41660891
Validation of the first commercial ELISA for type 2N von Willebrand's disease diagnosisQ45867954
Two novel type 2N von Willebrand disease-causing mutations that result in defective factor VIII binding, multimerization, and secretion of von Willebrand factorQ59511738
Recombinant expression of mutations causing von Willebrand disease type Normandy: characterization of a combined defect of factor VIII binding and multimerizationQ80234430
P433issue1
P304page(s)202-204
P577publication date2013-05-02
P1433published inThrombosis and HaemostasisQ15724413
P1476titleCompromised shear-dependent cleavage of type 2N von Willebrand factor variants by ADAMTS13 in the presence of factor VIII
P478volume110

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