scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1161/01.RES.0000252342.61447.A2 |
P8608 | Fatcat ID | release_e6njhibavfhvhnuj7eoghk233e |
P698 | PubMed publication ID | 17158347 |
P50 | author | Xuejun Wang | Q38361109 |
P2093 | author name string | Jeffrey Robbins | |
P433 | issue | 12 | |
P921 | main subject | heart failure | Q181754 |
quality control | Q827792 | ||
P304 | page(s) | 1315-1328 | |
P577 | publication date | 2006-12-01 | |
P1433 | published in | Circulation Research | Q2599020 |
P1476 | title | Heart failure and protein quality control | |
P478 | volume | 99 |
Q28602653 | A large dataset of protein dynamics in the mammalian heart proteome |
Q24337738 | A thrombospondin-dependent pathway for a protective ER stress response |
Q35661532 | AMP-activated protein kinase regulates E3 ligases in rodent heart |
Q93165000 | ATF6 as a Nodal Regulator of Proteostasis in the Heart |
Q34845287 | Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion. |
Q33699632 | Activation of the ubiquitin-proteasome system in doxorubicin cardiomyopathy. |
Q36726221 | Age influences inflammatory responses, hemodynamics, and cardiac proteasome activation during acute lung injury |
Q36803363 | Age- and Hypertension-Associated Protein Aggregates in Mouse Heart Have Similar Proteomic Profiles |
Q35879491 | Age-related changes in rat myocardium involve altered capacities of glycosaminoglycans to potentiate growth factor functions and heparan sulfate-altered sulfation |
Q39656906 | Aging and SKN-1-dependent Loss of 20S Proteasome Adaptation to Oxidative Stress in C. elegans. |
Q28571805 | Alpha B-crystallin suppresses pressure overload cardiac hypertrophy |
Q57813657 | Amelioration of desmin network defects by αB-crystallin overexpression confers cardioprotection in a mouse model of dilated cardiomyopathy caused by LMNA gene mutation |
Q40155868 | An Unbiased High-Throughput Screen to Identify Novel Effectors That Impact on Cardiomyocyte Aggregate Levels |
Q27694688 | An expanded role for AMP-activated protein kinase: regulator of myocardial protein degradation |
Q37526448 | Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease. |
Q37458369 | Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association. |
Q33685877 | Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy |
Q35124250 | Autophagy and p62 in cardiac proteinopathy. |
Q33733547 | Autophagy and the ubiquitin-proteasome system in cardiac dysfunction. |
Q35036537 | Bortezomib, a proteasome inhibitor, attenuates angiotensin II-induced hypertension and aortic remodeling in rats |
Q96586585 | CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes |
Q37688051 | Cardiac fibrosis in mouse expressing DsRed tetramers involves chronic autophagy and proteasome degradation insufficiency. |
Q42514689 | Cardiac sympathetic neurons provide trophic signal to the heart via β2-adrenoceptor-dependent regulation of proteolysis |
Q36772298 | Cardiac systolic dysfunction in doxorubicin-challenged rats is associated with upregulation of MuRF2 and MuRF3 E3 ligases |
Q52562672 | Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach. |
Q42382931 | Clarifying the cardiac proteasome paradox: protein quality control |
Q34708990 | Deficiencies in tRNA synthetase editing activity cause cardioproteinopathy. |
Q38828129 | Degradation of oxidized proteins by the proteasome: Distinguishing between the 20S, 26S, and immunoproteasome proteolytic pathways. |
Q37372239 | Delineation of Molecular Pathways Involved in Cardiomyopathies Caused by Troponin T Mutations |
Q33595728 | Deposition of nonsarcomeric alpha-actinin in cardiomyocytes from patients with dilated cardiomyopathy or chronic pressure overload. |
Q90074231 | Designing Novel Therapies to Mend Broken Hearts: ATF6 and Cardiac Proteostasis |
Q88633503 | Desmin and Cardiac Disease: An Unfolding Story |
Q42377369 | Desmin and αB-crystallin interplay in the maintenance of mitochondrial homeostasis and cardiomyocyte survival. |
Q35395372 | Desmin-related cardiomyopathy: an unfolding story |
Q37468899 | Diagnosis and Therapy of Atrial Fibrillation: The Past, The Present and The Future |
Q33842677 | Differential protein acetylation assists import of excess SOD2 into mitochondria and mediates SOD2 aggregation associated with cardiac hypertrophy in the murine SOD2-tg heart |
Q35990041 | Differential regulation of proteasome function in isoproterenol-induced cardiac hypertrophy |
Q36955453 | Do amyloid oligomers act as traps for misfolded proteins? A hypothesis |
Q41791468 | Doxycycline attenuates protein aggregation in cardiomyocytes and improves survival of a mouse model of cardiac proteinopathy |
Q40367733 | Endogenous muscle atrophy F-box mediates pressure overload-induced cardiac hypertrophy through regulation of nuclear factor-kappaB. |
Q35187068 | Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in mice |
Q34592321 | Enhancement of proteasome function by PA28α overexpression protects against oxidative stress. |
Q34541132 | Exercise training restores cardiac protein quality control in heart failure |
Q50040783 | FAT10 attenuates hypoxia-induced cardiomyocyte apoptosis by stabilizing caveolin-3. |
Q37116324 | Gambogic acid moderates cardiac responses to chronic hypoxia likely by acting on the proteasome and NF-κB pathway |
Q36184878 | Genetically induced moderate inhibition of the proteasome in cardiomyocytes exacerbates myocardial ischemia-reperfusion injury in mice |
Q40296185 | Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of MitoKATP in Energy Homeostasis |
Q36255416 | HALT & REVERSE: Hsf1 activators lower cardiomyocyt damage; towards a novel approach to REVERSE atrial fibrillation |
Q37864471 | Heterogeneous cardiac proteasomes: mandated by diverse substrates? |
Q91811120 | Highly Dynamic Changes in the Activity and Regulation of Macroautophagy in Hearts Subjected to Increased Proteotoxic Stress |
Q50055253 | Hspb7 is a cardioprotective chaperone facilitating sarcomeric proteostasis |
Q52371503 | Hypertrophic Cardiomyopathy: A Vicious Cycle Triggered by Sarcomere Mutations and Secondary Disease Hits. |
Q37225073 | Icariin protects rat cardiac H9c2 cells from apoptosis by inhibiting endoplasmic reticulum stress |
Q36252017 | Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease |
Q39994155 | Increased clearance of reactive aldehydes and damaged proteins in hypertension-induced compensated cardiac hypertrophy: impact of exercise training. |
Q54567140 | Inhibition of ubiquitin proteasome function suppresses proliferation of pulmonary artery smooth muscle cells. |
Q39880544 | Interplay between the ubiquitin-proteasome system and autophagy in proteinopathies. |
Q37012635 | Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy |
Q35721399 | Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction |
Q42910017 | Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy. |
Q38473474 | Mechanisms and management of doxorubicin cardiotoxicity |
Q92733130 | Mitochondrial Quality Control: Role in Cardiac Models of Lethal Ischemia-Reperfusion Injury |
Q90674899 | Molecular Insights into Muscle Homeostasis, Atrophy and Wasting |
Q37688943 | Muscarinic 2 receptors modulate cardiac proteasome function in a protein kinase G-dependent manner |
Q24673171 | Myosin accumulation and striated muscle myopathy result from the loss of muscle RING finger 1 and 3 |
Q43187716 | Myosin assembly, maintenance and degradation in muscle: Role of the chaperone UNC-45 in myosin thick filament dynamics |
Q36092993 | NEDD8 Ultimate Buster 1 Long (NUB1L) Protein Suppresses Atypical Neddylation and Promotes the Proteasomal Degradation of Misfolded Proteins |
Q34352826 | Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor. |
Q34199818 | O-linked β-N-acetylglucosamine transferase is indispensable in the failing heart. |
Q33543763 | PARM-1 is an endoplasmic reticulum molecule involved in endoplasmic reticulum stress-induced apoptosis in rat cardiac myocytes |
Q46212543 | PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts |
Q46232820 | Paradoxical resistance to myocardial ischemia and age-related cardiomyopathy in NHE1 transgenic mice: a role for ER stress? |
Q34474447 | Perturbation of cullin deneddylation via conditional Csn8 ablation impairs the ubiquitin-proteasome system and causes cardiomyocyte necrosis and dilated cardiomyopathy in mice. |
Q47162304 | Phospholamban Is Downregulated by pVHL-Mediated Degradation through Oxidative Stress in Failing Heart |
Q30341525 | Phylogenetic origin of LI-cadherin revealed by protein and gene structure analysis. |
Q38074944 | Posttranslational modification and quality control. |
Q36865776 | Primary proteasome inhibition results in cardiac dysfunction |
Q28084015 | Priming the proteasome by protein kinase G: a novel cardioprotective mechanism of sildenafil |
Q38970493 | Proteasome dysfunction in cardiomyopathies. |
Q33554490 | Proteasome inhibitors and cardiac cell growth |
Q35536300 | Proteasome malfunction activates macroautophagy in the heart |
Q92027205 | Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy |
Q37541537 | Protein degradation systems in viral myocarditis leading to dilated cardiomyopathy |
Q36952213 | Protein quality control and degradation in cardiomyocytes |
Q28730834 | Protein quality control disruption by PKCβII in heart failure; rescue by the selective PKCβII inhibitor, βIIV5-3 |
Q37256593 | Proteomic insights into cardiac cell death and survival |
Q34002691 | Proteomic profiling of endothelin-1-stimulated hypertrophic cardiomyocytes reveals the increase of four different desmin species and alpha-B-crystallin |
Q38497014 | Proteotoxicity and cardiac dysfunction |
Q89978268 | Remote Ischemic Preconditioning induces Cardioprotective Autophagy and Signals through the IL-6-Dependent JAK-STAT Pathway |
Q42565727 | Rescuing cardiac malfunction: the roles of the chaperone-like small heat shock proteins. |
Q38265521 | Rethinking cardiac metabolism: metabolic cycles to refuel and rebuild the failing heart |
Q60946590 | Role of Autophagy in Proteostasis: Friend and Foe in Cardiac Diseases |
Q92724115 | Role of the COP9 Signalosome (CSN) in Cardiovascular Diseases |
Q35898986 | Roles for endoplasmic reticulum-associated degradation and the novel endoplasmic reticulum stress response gene Derlin-3 in the ischemic heart |
Q91640802 | SPRED2 deficiency elicits cardiac arrhythmias and premature death via impaired autophagy |
Q35951259 | Seven-transmembrane receptors and ubiquitination |
Q34696154 | Signaling and myosin-binding protein C. |
Q36784081 | Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent Manner |
Q49633837 | Sparse simultaneous signal detection for identifying genetically controlled disease genes |
Q35045905 | Taking pressure off the heart: the ins and outs of atrophic remodelling |
Q50914295 | Targeting the ubiquitin proteasome system in diabetic cardiomyopathy. |
Q35700589 | The COP9 signalosome and vascular function: intriguing possibilities? |
Q34778984 | The interplay between autophagy and the ubiquitin-proteasome system in cardiac proteotoxicity |
Q37788836 | The role of the proteasome in heart disease |
Q30366262 | The role of the unfolded protein response in the heart. |
Q28280898 | The ubiquitin proteasome system and myocardial ischemia |
Q33816688 | The ubiquitin proteasome system in human cardiomyopathies and heart failure |
Q27021582 | The ubiquitin-proteasome system and cardiovascular disease |
Q33554497 | The ubiquitin-proteasome system in cardiac proteinopathy: a quality control perspective |
Q34615889 | Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signaling |
Q89814914 | Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination |
Q35147643 | Ubiquitin carboxyl terminal hydrolyase L1-suppressed autophagic degradation of p21WAF1/Cip1 as a novel feedback mechanism in the control of cardiac fibroblast proliferation |
Q28273319 | Ubiquitin proteasome dysfunction in human hypertrophic and dilated cardiomyopathies |
Q36606405 | Ubiquitin receptors and protein quality control |
Q46727503 | Upregulation of myocardial 11S-activated proteasome in experimental hyperglycemia |
Q37587303 | Upregulation of proteasome activity rescues cardiomyocytes following pulse treatment with a proteasome inhibitor |
Q57803549 | Ushering in the cardiac role of Ubiquilin1 |
Q92478391 | Vezf1 regulates cardiac structure and contractile function |
Q37876416 | Viral myocarditis: potential defense mechanisms within the cardiomyocyte against virus infection |
Q33710767 | c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia |
Q28581185 | c-Cbl ubiquitin ligase regulates focal adhesion protein turnover and myofibril degeneration induced by neutrophil protease cathepsin G |
Q27000980 | p62 Stages an interplay between the ubiquitin-proteasome system and autophagy in the heart of defense against proteotoxic stress |
Q35872556 | Β-adrenergic receptor stimulation induces endoplasmic reticulum stress in adult cardiac myocytes: role in apoptosis |
Search more.