Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease.

scientific article published on January 2008

Appetite for destruction: E3 ubiquitin-ligase protection in cardiac disease. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.2217/14796678.4.1.65
P932PMC publication ID2699281
P698PubMed publication ID19543439
P5875ResearchGate publication ID26308130

P50authorMonte WillisQ38322683
Jonathan SchislerQ43080201
P2093author name stringCam Patterson
P2860cites workMutations in beta-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-CQ22008775
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A newly created splice donor site in exon 25 of the MyBP-C gene is responsible for inherited hypertrophic cardiomyopathy with incomplete disease penetranceQ28139924
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Effect of acetylsalicylic acid on endogenous I kappa B kinase activity in lung epithelial cellsQ28174796
Hypertrophic cardiomyopathy: distribution of disease genes, spectrum of mutations, and implications for a molecular diagnosis strategyQ28198707
Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injuryQ44210996
Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathwayQ44760490
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Inhibition of the ubiquitin-proteasome pathway induces differential heat-shock protein response in cardiomyocytes and renders early cardiac protectionQ45713461
A randomized, double-blinded, placebo-controlled multicenter trial of adenosine as an adjunct to reperfusion in the treatment of acute myocardial infarction (AMISTAD-II).Q46528602
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Statins prevent NF-kappaB transactivation independently of the IKK-pathway in human endothelial cellsQ46624092
Proteasome inhibition attenuates infarct size and preserves cardiac function in a murine model of myocardial ischemia-reperfusion injury.Q47282390
COOH-terminal truncated cardiac myosin-binding protein C mutants resulting from familial hypertrophic cardiomyopathy mutations exhibit altered expression and/or incorporation in fetal rat cardiomyocytesQ47898149
CHIP chaperones wild type p53 tumor suppressor protein.Q51578869
CHIP, a cochaperone/ubiquitin ligase that regulates protein quality control, is required for maximal cardioprotection after myocardial infarction in mice.Q51594198
Chronic proteasome inhibition contributes to coronary atherosclerosis.Q51739024
Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.Q51751869
Myocardial expression of Murf-1 and MAFbx after induction of chronic heart failure: Effect on myocardial contractilityQ61896386
Cardiac protein synthesis and degradation during thyroxine-induced left ventricular hypertrophyQ70016121
Unexpected cardiotoxicity in haematological bortezomib treated patientsQ80463636
Functional properties of the titin/connectin-associated proteins, the muscle-specific RING finger proteins (MURFs), in striated muscleQ82548298
Protein synthesis and degradation during regression of thyroxine-induced cardiac hypertrophyQ93524527
Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutantsQ28239896
A molecular map of the interactions between titin and myosin-binding protein C. Implications for sarcomeric assembly in familial hypertrophic cardiomyopathyQ28278861
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivationQ28280958
Familial hypertrophic cardiomyopathy: from mutations to functional defectsQ28282839
In vivo modeling of myosin binding protein C familial hypertrophic cardiomyopathyQ28512273
Regulation of microtubule dynamics and myogenic differentiation by MURF, a striated muscle RING-finger proteinQ28513866
Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heartQ28574395
Cardiac hypertrophy: the good, the bad, and the uglyQ29615247
Protein degradation and protection against misfolded or damaged proteinsQ29618400
Structural evidence for the interaction of C-protein (MyBP-C) with actin and sequence identification of a possible actin-binding domain.Q33338599
A phase I/II study of arsenic trioxide/bortezomib/ascorbic acid combination therapy for the treatment of relapsed or refractory multiple myelomaQ33374572
The ubiquitin signal: assembly, recognition and termination. Symposium on ubiquitin and signalingQ34360569
The kinase domain of titin controls muscle gene expression and protein turnoverQ34407820
Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.Q34617875
MLN-519. Millennium/PAIONQ35123169
Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structuresQ35621909
Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarctionQ35721399
Kinomics: methods for deciphering the kinomeQ36079218
Atrogin-1 inhibits Akt-dependent cardiac hypertrophy in mice via ubiquitin-dependent coactivation of Forkhead proteinsQ36088932
Muscle ring finger protein-1 inhibits PKC{epsilon} activation and prevents cardiomyocyte hypertrophyQ36322902
Regulating the regulator: NF-kappaB signaling in heartQ36583897
Heart failure and protein quality controlQ36678579
A ubiquitin mutant with specific defects in DNA repair and multiubiquitinationQ40015739
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complexQ40177208
Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, an E3 ubiquitin ligaseQ40341746
Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptideQ40431933
NF-kappa B and rel proteins in innate immunityQ40519638
A proteasome inhibitor confers cardioprotectionQ40580614
Triggers for sudden cardiac death in the athlete.Q41047262
Biomolecular interactions between human recombinant β-MyHC and cMyBP-Cs implicated in familial hypertrophic cardiomyopathyQ42046156
Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signalingQ42500888
Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivoQ42750583
Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2.Q42833116
Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradationQ42917499
PR-39 and PR-11 peptides inhibit ischemia-reperfusion injury by blocking proteasome-mediated I kappa B alpha degradationQ43800033
Ubiquitin-proteasome pathway as a new target for the prevention of restenosisQ43869296
P433issue1
P921main subjectappetiteQ28578
P304page(s)65-75
P577publication date2008-01-01
P1433published inFuture CardiologyQ15765184
P1476titleAppetite for destruction: E3 ubiquitin-ligase protection in cardiac disease
P478volume4

Reverse relations

cites work (P2860)
Q28078724A Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?
Q37476330Allele-specific expression in the human heart and its application to postoperative atrial fibrillation and myocardial ischemia.
Q42770507Chaperoning myosin assembly in muscle formation and aging
Q33769449Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study
Q28296634Hold me tight: Role of the heat shock protein family of chaperones in cardiac disease
Q88664220Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling in Vivo
Q36934990Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia
Q33893441Mining the TRAF6/p62 interactome for a selective ubiquitination motif
Q33584306Muscle RING finger-1 promotes a maladaptive phenotype in chronic hypoxia-induced right ventricular remodeling
Q34603561Muscle ring finger 1 mediates cardiac atrophy in vivo
Q34760711NF-κB inhibition protects against tumor-induced cardiac atrophy in vivo.
Q36952213Protein quality control and degradation in cardiomyocytes
Q37628822Seek and destroy: the ubiquitin----proteasome system in cardiac disease.
Q33679929Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease
Q27026951Targeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategies
Q53548334The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation.
Q34760678The ubiquitin ligase MuRF1 protects against cardiac ischemia/reperfusion injury by its proteasome-dependent degradation of phospho-c-Jun.

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