Rationalising the role of Keratin 9 as a biomarker for Alzheimer's disease

scientific article published on 14 March 2016

Rationalising the role of Keratin 9 as a biomarker for Alzheimer's disease is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1052429454
P356DOI10.1038/SREP22962
P932PMC publication ID4789650
P698PubMed publication ID26973255
P5875ResearchGate publication ID298325634

P50authorKevin MorganQ56356187
Joanna L RichensQ56440604
Paul O'SheaQ56440605
P2093author name stringNin Bajaj
Fiona Cantlay
Hannah L Spencer
Kelly-Ann Vere
Molly Butler
P2860cites workA physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathwayQ21735927
Intestinal epithelial cells secrete exosome-like vesiclesQ24291534
An investigation into the human serum "interactome"Q24294835
Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defectQ24295031
Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulinQ24295284
A census of human soluble protein complexesQ24297808
The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformationQ24299494
The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexusQ24301338
Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathwaysQ24302034
Molecular characterization of the body site-specific human epidermal cytokeratin 9: cDNA cloning, amino acid sequence, and tissue specificity of gene expressionQ24305039
Proteomic characterization of the human sperm nucleusQ24305129
Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6Q24314482
Charting the molecular network of the drug target Bcr-AblQ24317707
An integrated workflow for charting the human interaction proteome: insights into the PP2A systemQ24318802
Defining the membrane proteome of NK cellsQ24323157
Network organization of the human autophagy systemQ24324004
A human protein-protein interaction network: a resource for annotating the proteomeQ24324450
Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approachQ24337286
Biosensor-based micro-affinity purification for the proteomic analysis of protein complexesQ24337793
The Reactome pathway knowledgebaseQ24567743
The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer diseaseQ26777969
FoxP1 orchestration of ASD-relevant signaling pathways in the striatumQ27322723
Current and future implications of basic and translational research on amyloid-β peptide production and removal pathwaysQ28081678
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organizationQ28278217
Reactome: a database of reactions, pathways and biological processesQ28298042
Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitmentQ28727031
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathwayQ29870999
Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's diseaseQ30495250
Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach.Q31151924
Assignment of human plasma polypeptides on a nondenaturing 2-D gel using MALDI-MS and PMF and comparisons with the results of intact protein mapping.Q33271725
Proteomic analysis reveals novel binding partners of MIP-T3 in human cellsQ33292249
Proteomic analysis of human blood serum using peptide library beadsQ33299347
Profiling carbonylated proteins in human plasmaQ33528052
Data management and functional annotation of the Korean reference plasma proteomeQ33533411
Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stabilityQ33669652
The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinomaQ33974989
Predictome: a database of putative functional links between proteinsQ34010645
Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluidQ34063961
Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profilingQ34073510
Mutations in the keratin 9 gene in Pakistani families with epidermolytic palmoplantar keratodermaQ34154117
A systems wide mass spectrometric based linear motif screen to identify dominant in-vivo interacting proteins for the ubiquitin ligase MDM2.Q43540034
Characterization of differences between blood sample matrices in untargeted metabolomicsQ46925183
Albumin and immunoglobulin in plasma and cerebrospinal fluid, and blood-cerebrospinal fluid barrier function in patients with dementia of Alzheimer type and multi-infarct dementiaQ48766140
Dickkopf 1 (DKK1) regulates skin pigmentation and thickness by affecting Wnt/beta-catenin signaling in keratinocytesQ50454634
Reverse engineering of Alzheimer's disease based on biomarker pathways analysis.Q50620148
Roles of serum fibrinogen α chain-derived peptides in Alzheimer's disease.Q53345656
Alzheimer's diseaseQ55880664
Integrative analysis of the ubiquitin proteome isolated using Tandem Ubiquitin Binding Entities (TUBEs)Q58494051
Wnt signaling function in Alzheimer's diseaseQ74248964
High-sensitivity analysis of human plasma proteome by immobilized isoelectric focusing fractionation coupled to mass spectrometry identificationQ81012860
A novel mutation within the 2B rod domain of keratin 9 in a Chinese pedigree with epidermolytic palmoplantar keratoderma combined with knuckle pads and camptodactylyQ84469991
[Serum proteomic analysis on metastasis-associated proteins of hepatocellular carcinoma]Q84585246
Proteomic analysis of the cerebrospinal fluid in multiple sclerosis and neuromyelitis optica patientsQ84806086
Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomicsQ34154148
Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5Q34154655
Soluble plasma HLA peptidome as a potential source for cancer biomarkersQ34279102
Keratin 9 gene mutations in epidermolytic palmoplantar keratoderma (EPPK).Q34291582
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomicsQ34433677
Apolipoprotein A-IV as a novel gene associated with polycystic ovary syndromeQ34556672
Apolipoprotein E in synaptic plasticity and Alzheimer's disease: potential cellular and molecular mechanismsQ34628212
The human keratins: biology and pathologyQ34776574
Precursor acquisition independent from ion count: how to dive deeper into the proteomics ocean.Q34910930
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer diseaseQ35034130
A high-confidence human plasma proteome reference set with estimated concentrations in PeptideAtlasQ35264564
Mapping the human plasma proteome by SCX-LC-IMS-MSQ36375781
Activity of P-Glycoprotein, a β-Amyloid Transporter at the Blood-Brain Barrier, Is Compromised in Patients with Mild Alzheimer Disease.Q36404535
The heme degradation pathway is a promising serum biomarker source for the early detection of Alzheimer's diseaseQ36660120
A combined dataset of human cerebrospinal fluid proteins identified by multi-dimensional chromatography and tandem mass spectrometryQ36702842
Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer diseaseQ36932748
VisANT 4.0: Integrative network platform to connect genes, drugs, diseases and therapiesQ36953937
Wnt/beta-catenin signaling controls development of the blood-brain barrierQ36955697
The Wnt antagonist, Dickkopf-1, as a target for the treatment of neurodegenerative disorders.Q37144218
Keratin 9 is required for the structural integrity and terminal differentiation of the palmoplantar epidermis.Q37581752
RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.Q37687704
The regulation of brain states by neuroactive substances distributed via the cerebrospinal fluid; a reviewQ37692949
The role of the ubiquitin proteasome system in Alzheimer's diseaseQ37850624
Wnt/β-catenin signaling in Alzheimer's disease.Q38173457
Dysregulated expression of dickkopfs for potential detection of hepatocellular carcinoma.Q38210247
Dysfunctional Wnt/β-catenin signaling contributes to blood-brain barrier breakdown in Alzheimer's diseaseQ38214560
Beyond expectations: novel insights into epidermal keratin function and regulationQ38222233
Robust gene network analysis reveals alteration of the STAT5a network as a hallmark of prostate cancer.Q38342896
Visualization and biochemical analyses of the emerging mammalian 14-3-3-phosphoproteomeQ38900580
Activation of the Wnt/β-catenin pathway represses the transcription of the β-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoterQ38941464
The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stabilityQ39196735
Cerebrospinal fluid levels of β-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementiaQ39668296
Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseasesQ39860782
Practical detection of a definitive biomarker panel for Alzheimer's disease; comparisons between matched plasma and cerebrospinal fluidQ40950201
Structure and assembly of hemidesmosomesQ41017393
Integrated genomic approaches identify major pathways and upstream regulators in late onset Alzheimer's diseaseQ42134488
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
biomarkerQ864574
P304page(s)22962
P577publication date2016-03-14
P1433published inScientific ReportsQ2261792
P1476titleRationalising the role of Keratin 9 as a biomarker for Alzheimer's disease
P478volume6

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