scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1038/SJ.GT.3302907 |
P8608 | Fatcat ID | release_kfl2kokftjegflkqhiwsqghdti |
P698 | PubMed publication ID | 17215847 |
P5875 | ResearchGate publication ID | 6585369 |
P2093 | author name string | Wang Q | |
Prud'homme GJ | |||
Draghia-Akli R | |||
P2860 | cites work | Plasmid DNA vaccines: investigation of integration into host cellular DNA following intramuscular injection in mice | Q95721015 |
Plasmid DNA vaccines: tissue distribution and effects of DNA sequence, adjuvants and delivery method on integration into host DNA | Q95721016 | ||
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self | Q29619194 | ||
Nonviral gene transfer to skeletal, smooth, and cardiac muscle in living animals | Q30431522 | ||
Synthetic muscle promoters: activities exceeding naturally occurring regulatory sequences | Q30657785 | ||
Dermatologic and immunologic findings in the immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome | Q33360497 | ||
DNA immunization to prevent autoimmune diabetes | Q33855482 | ||
Immunotherapeutic gene transfer into muscle | Q34207629 | ||
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice | Q34345367 | ||
Plasmid DNA entry into postmitotic nuclei of primary rat myotubes | Q34345977 | ||
Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents | Q34531086 | ||
CpG motifs in bacterial DNA and their immune effects | Q34542287 | ||
TGF-beta requires CTLA-4 early after T cell activation to induce FoxP3 and generate adaptive CD4+CD25+ regulatory cells | Q34565392 | ||
Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B:9-23 and B:13-23 | Q34797949 | ||
High-efficiency gene transfer into skeletal muscle mediated by electric pulses | Q35123357 | ||
Treatment of murine lupus with cDNA encoding IFN-gammaR/Fc | Q35126621 | ||
Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis | Q35159540 | ||
Altering immune tolerance therapeutically: the power of negative thinking | Q35600811 | ||
Prevention of autoimmune diabetes by DNA vaccination | Q35623332 | ||
Naturally-occurring CD4+CD25+ immunoregulatory T cells: central players in the arena of peripheral tolerance | Q35703487 | ||
Immunotherapeutic uses of CpG oligodeoxynucleotides | Q35730784 | ||
Strategies for improved formulation and delivery of DNA vaccines to veterinary target species | Q35826384 | ||
DNA vaccines to attack cancer | Q35855143 | ||
DNA electrotransfer: its principles and an updated review of its therapeutic applications | Q35904419 | ||
DNA vaccination against tumors | Q35945955 | ||
The NOD mouse: a model of immune dysregulation | Q36072434 | ||
AIRE and APECED: molecular insights into an autoimmune disease | Q36079891 | ||
Disruption of immunological tolerance: role of AIRE gene in autoimmunity. | Q36375744 | ||
Plasmid-mediated muscle-targeted gene therapy for circulating therapeutic protein replacement: a tale of the tortoise and the hare? | Q36395622 | ||
FOXP3: of mice and men. | Q36427333 | ||
Type I regulatory T cells in autoimmunity and inflammatory diseases | Q36443071 | ||
Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases | Q36447098 | ||
Regulatory T cells in human disease and their potential for therapeutic manipulation | Q36455974 | ||
Lessons on autoimmune diabetes from animal models | Q36475432 | ||
Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus | Q36593611 | ||
In vivo electroporation for gene therapy | Q36593614 | ||
Treatment with intramuscular vascular endothelial growth factor gene compared with placebo for patients with diabetes mellitus and critical limb ischemia: a double-blind randomized trial. | Q39349848 | ||
Gene therapy of diabetes using a novel GLP-1/IgG1-Fc fusion construct normalizes glucose levels in db/db mice | Q40237694 | ||
Cutting edge: deficiency in the E3 ubiquitin ligase Cbl-b results in a multifunctional defect in T cell TGF-beta sensitivity in vitro and in vivo | Q40327455 | ||
Intramuscular administration of expression plasmids encoding interferon-gamma receptor/IgG1 or IL-4/IgG1 chimeric proteins protects from autoimmunity | Q40831887 | ||
Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein | Q40925888 | ||
Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle | Q41607156 | ||
Regulatory cytokine production stimulated by DNA vaccination against an altered form of glutamic acid decarboxylase 65 in nonobese diabetic mice | Q42439416 | ||
DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes | Q42687538 | ||
Electroporation-facilitated delivery of plasmid DNA in skeletal muscle: plasmid dependence of muscle damage and effect of poloxamer 188. | Q43799580 | ||
Gene therapy of streptozotocin-induced diabetes by intramuscular delivery of modified preproinsulin genes | Q44429992 | ||
Direct gene transfer into mouse muscle in vivo | Q44656494 | ||
Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active-surveillance report | Q45180236 | ||
Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase. | Q45731838 | ||
Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation | Q45871690 | ||
Effects of plasmid DNA injection on cyclophosphamide-accelerated diabetes in NOD mice | Q45876398 | ||
Electroporative transfection with KGF-1 DNA improves wound healing in a diabetic mouse model | Q45878634 | ||
Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primates | Q45879163 | ||
Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia | Q45886388 | ||
Immunization with DNA encoding an immunodominant peptide of insulin prevents diabetes in NOD mice | Q46058127 | ||
Vaccination with glutamic acid decarboxylase plasmid DNA protects mice from spontaneous autoimmune diabetes and B7/CD28 costimulation circumvents that protection | Q46193568 | ||
Tissue-specific characteristics of in vivo electric gene: transfer by tissue and intravenous injection of plasmid DNA. | Q46538472 | ||
Differential immune response to B:9-23 insulin 1 and insulin 2 peptides in animal models of type 1 diabetes | Q47241677 | ||
Lower limb amputations in Southern Finland in 2000 and trends up to 2001. | Q47269781 | ||
Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device. | Q51358473 | ||
Gene transfer into muscle by electroporation in vivo. | Q51501466 | ||
Immunoinhibitory DNA vaccine protects against autoimmune diabetes through cDNA encoding a selective CTLA-4 (CD152) ligand. | Q52937532 | ||
Protective regulatory T cell generation in autoimmune diabetes by DNA covaccination with islet antigens and a selective CTLA-4 ligand | Q56901937 | ||
Gene Electrotransfer Results in a High-Level Transduction of Rat Skeletal Muscle and Corrects Anemia of Renal Failure | Q58535589 | ||
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope | Q59060541 | ||
DNA vaccination with glutamic acid decarboxylase (GAD) generates a strong humoral immune response in BALB/c, C57BL/6, and in diabetes-prone NOD mice | Q59348684 | ||
The management and outcome of critical limb ischaemia in diabetic patients: results of a national survey. Audit Committee of the Vascular Surgical Society of Great Britain and Ireland | Q71666422 | ||
Vaccination with empty plasmid DNA or CpG oligonucleotide inhibits diabetes in nonobese diabetic mice: modulation of spontaneous 60-kDa heat shock protein autoimmunity | Q73209258 | ||
More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice | Q73552907 | ||
Erythropoietin secretion and physiological effect in mouse after intramuscular plasmid DNA electrotransfer | Q73595843 | ||
Survival in patients with chronic lower extremity ischemia: a risk factor analysis | Q73607575 | ||
Nonclinical toxicology in support of licensure of gene therapies. Arlington, VA, USA, March 13-14, 2003 | Q73693498 | ||
Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice | Q74065177 | ||
Decreasing incidence of major amputations in people with diabetes | Q74204296 | ||
Plasmid vaccination with insulin B chain prevents autoimmune diabetes in nonobese diabetic mice | Q74388336 | ||
Electroporation improves the efficacy of DNA vaccines in large animals | Q74733724 | ||
Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes | Q74844394 | ||
Induction of autoimmune diabetes through insulin (but not GAD65) DNA vaccination in nonobese diabetic and in RIP-B7.1 mice | Q78431873 | ||
Electroporatic delivery of TGF-beta1 gene works synergistically with electric therapy to enhance diabetic wound healing in db/db mice | Q80576664 | ||
Insulin-like growth factor-I gene transfer by electroporation prevents skeletal muscle atrophy in glucocorticoid-treated rats | Q81300294 | ||
Highly efficient constant-current electroporation increases in vivo plasmid expression | Q81582446 | ||
Intranasal vaccination with proinsulin DNA induces regulatory CD4+ T cells that prevent experimental autoimmune diabetes | Q83059279 | ||
Pro-apoptotic DNA vaccination ameliorates new onset of autoimmune diabetes in NOD mice and induces foxp3+ regulatory T cells in vitro | Q83168646 | ||
P433 | issue | 7 | |
P921 | main subject | gene therapy | Q213901 |
P304 | page(s) | 553-564 | |
P577 | publication date | 2007-01-11 | |
P1433 | published in | Gene Therapy | Q15763095 |
P1476 | title | Plasmid-based gene therapy of diabetes mellitus | |
P478 | volume | 14 |
Q33723334 | A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin |
Q53272516 | A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin. |
Q42821683 | A site-specific genomic integration strategy for sustained expression of glucagon-like peptide-1 in mouse muscle for controlling energy homeostasis |
Q35762883 | Antigen-specific therapeutic approaches in Type 1 diabetes |
Q42410705 | Combined effects of IL-12 and electroporation enhances the potency of DNA vaccination in macaques |
Q36694873 | Contactless magneto-permeabilization for intracellular plasmid DNA delivery in-vivo |
Q37590340 | DNA vaccines for autoimmune diseases |
Q36117595 | Diabetes mellitus: new challenges and innovative therapies |
Q33547705 | Efficient gene delivery and silencing of mouse and human pancreatic islets |
Q30476834 | Electroporation advances in large animals |
Q38285418 | Electroporation-enhanced delivery of nucleic acid vaccines |
Q35826661 | Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation |
Q34121750 | Encapsulation of plasmid DNA in calcium phosphate nanoparticles: stem cell uptake and gene transfer efficiency |
Q45870446 | Engineered Epidermal Progenitor Cells Can Correct Diet-Induced Obesity and Diabetes |
Q40420214 | Enhanced Delivery of DNA or RNA Vaccines by Electroporation |
Q40291436 | Enhancement of the immunogenicity of an alphavirus replicon-based DNA vaccine against classical swine fever by electroporation and coinjection with a plasmid expressing porcine interleukin 2. |
Q36993836 | Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice |
Q45872071 | Immunity against a therapeutic xenoprotein/Fc construct delivered by gene transfer is reduced through binding to the inhibitory receptor FcγRIIb. |
Q37472002 | In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance |
Q80204825 | Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques |
Q36921222 | Pathobiology of transforming growth factor beta in cancer, fibrosis and immunologic disease, and therapeutic considerations |
Q33901714 | Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide 1 |
Q30395101 | Prototype development and preclinical immunogenicity analysis of a novel minimally invasive electroporation device. |
Q37550619 | Skin Transfection Patterns and Expression Kinetics of Electroporation-Enhanced Plasmid Delivery Using the CELLECTRA-3P, a Portable Next-Generation Dermal Electroporation Device |
Q55260402 | Tolerogenic β2-glycoprotein I DNA vaccine and FK506 as an adjuvant attenuates experimental obstetric antiphospholipid syndrome. |
Q33985556 | Transfection of rat pancreatic islet tissue by polymeric gene vectors |
Q37804398 | Treatment of diabetes with glucagon-like peptide-1 gene therapy |
Q36299378 | Treatment with MOG-DNA vaccines induces CD4+CD25+FoxP3+ regulatory T cells and up-regulates genes with neuroprotective functions in experimental autoimmune encephalomyelitis. |
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