Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device.

scientific article published on 24 August 2005

Successful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VACCINE.2005.08.049
P698PubMed publication ID16150516
P5875ResearchGate publication ID7610653

P2093author name stringAmir Khan
Ruxandra Draghia-Akli
Heather Attra
Henry Hebel
P2860cites workModulation of immune responses to bovine herpesvirus-1 in cattle by immunization with a DNA vaccine encoding glycoprotein D as a fusion protein with bovine CD154.Q47593314
Increased gene expression and inflammatory cell infiltration caused by electroporation are both important for improving the efficacy of DNA vaccinesQ47727853
Priming of piglets against enterotoxigenic E. coli F4 fimbriae by immunisation with FAEG DNA.Q47805238
Improvement of DNA vaccine immunogenicity by a dual antigen expression systemQ47971522
Purification of pharmaceutical-grade plasmid DNA by anion-exchange chromatography in an RNase-free process.Q53641366
Optimization of DNA vaccination immune responses in dairy cows: effect of injection site and the targeting efficacy of antigen-bCTLA-4 complexQ56903886
Self-administration with UniJect of the once-a-month injectable contraceptive CyclofemQ74072051
Theoretical analysis of localized heating in human skin subjected to high voltage pulsesQ74243985
Kinetics of the temperature rise within human stratum corneum during electroporation and pulsed high-voltage iontophoresisQ74243989
Factors influencing the efficacy, longevity, and safety of electroporation-assisted plasmid-based gene transfer into mouse musclesQ80507043
A rapid alkaline extraction procedure for screening recombinant plasmid DNAQ24614998
At-birth immunisation against hepatitis B using a novel pre-filled immunisation device stored outside the cold chainQ30638046
Oxytocin in prefilled Uniject injection devices for managing third-stage labor in IndonesiaQ31002543
Issues for improving multiplasmid DNA vaccines for HIV-1.Q34619954
Improvement of nonviral gene therapy by Epstein-Barr virus (EBV)-based plasmid vectorsQ34791491
Electroporation: theory and methods, perspectives for drug delivery, gene therapy and researchQ35089200
Perspectives on plasmid-based gene therapy: challenges for the product and the processQ35097555
Plasmid DNA purificationQ35673340
Electroporation for gene transfer to skeletal muscles: current statusQ35782833
A prefilled injection device for outreach tetanus immunization by Bolivian traditional birth attendantsQ38550231
Impact of intrinsic DNA structure on processing of plasmids for gene therapy and DNA vaccines.Q40471003
Large-scale capture and partial purification of plasmid DNA using anion-exchange membrane capsulesQ44375706
Evaluation of an ion‐exchange membrane for the purification of plasmid DNAQ44399492
Integrated process for purification of plasmid DNA using aqueous two-phase systems combined with membrane filtration and lid bead chromatographyQ45177313
Use of a Sindbis virus DNA-based expression vector for induction of protective immunity against pseudorabies virus in pigsQ45722894
Production of plasmid DNA for human gene therapy using modified alkaline cell lysis and expanded bed anion exchange chromatographyQ45866252
Accelerated immune response to DNA vaccinesQ46301816
P433issue21
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)4607-4614
P577publication date2005-08-24
P1433published inVaccineQ7907941
P1476titleSuccessful parallel development and integration of a plasmid-based biologic, container/closure system and electrokinetic delivery device.
P478volume24

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cites work (P2860)
Q54359189A continuous cell alkaline lysis, neutralization, and clarification combination process for production of plasmid pUDK-HGF.
Q36288704Adiponectin gene therapy ameliorates high-fat, high-sucrose diet-induced metabolic perturbations in mice
Q41899321Antibiotic-free production of a herpes simplex virus 2 DNA vaccine in a high yield cGMP process
Q61822538DNA immunization using constant-current electroporation affords long-term protection from autochthonous mammary carcinomas in cancer-prone transgenic mice
Q37590348DNA vaccine manufacture: scale and quality
Q50653876Double-blinded, Placebo-controlled plasmid GHRH trial for cancer-associated anemia in dogs.
Q37622247Electrodes for in vivo localised subcutaneous electropulsation and associated drug and nucleic acid delivery
Q36981658Electroporation-based DNA immunisation: translation to the clinic
Q33346277Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens
Q80204825Intradermal/subcutaneous immunization by electroporation improves plasmid vaccine delivery and potency in pigs and rhesus macaques
Q36428352Markedly enhanced immunogenicity of a Pfs25 DNA-based malaria transmission-blocking vaccine by in vivo electroporation
Q34910424Multivalent smallpox DNA vaccine delivered by intradermal electroporation drives protective immunity in nonhuman primates against lethal monkeypox challenge
Q36704473Plasmid-based gene therapy of diabetes mellitus
Q36694825Preclinical evaluation of the immunogenicity and safety of plasmid DNA-based prophylactic vaccines for human cytomegalovirus.
Q38259502Production and purification of plasmid DNA vaccines: is there scope for further innovation?
Q84863673Production of pharmaceutical-grade plasmids at high concentration and high supercoiled percentage

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