Characterization of passive permeability at the blood-tumor barrier in five preclinical models of brain metastases of breast cancer

scientific article published on 5 March 2016

Characterization of passive permeability at the blood-tumor barrier in five preclinical models of brain metastases of breast cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10585-016-9784-Z
P932PMC publication ID4804888
P698PubMed publication ID26944053

P2093author name stringAfroz S Mohammad
Chris E Adkins
Paul R Lockman
Neal Shah
Emma L Dolan
Tori B Terrell-Hall
Jessica Griffith
Emily Sechrest
P2860cites workPhysicochemical and pharmacokinetic parameters of seven lipophilic chlorambucil esters designed for brain penetrationQ59606560
Nontransgenic models of breast cancerQ24800700
Molecular determinants of blood-brain barrier permeationQ26797482
Gliomas and the vascular fragility of the blood brain barrierQ28081953
Structure and function of the blood-brain barrierQ29615699
The blood-brain barrier/neurovascular unit in health and diseaseQ29616335
Intracranial metastases: spectrum of MR imaging findingsQ30574051
Brain metastases from breast cancer: lessons from experimental magnetic resonance imaging studies and clinical implications.Q30708273
Brain metastases of breast cancer.Q31111302
Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brainQ33283845
Imagable 4T1 model for the study of late stage breast cancerQ33358981
Characteristics of compounds that cross the blood-brain barrierQ33469828
Advances in imaging low-grade gliomasQ33526612
Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental studyQ34032708
Vascular structures in brain tumorsQ34045197
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeabilityQ34057451
The use of Gd DTPA as a perfusion agent and marker of blood-brain barrier disruptionQ34195312
Breast tumor cell lines from pleural effusionsQ34209613
The blood-brain and blood-tumor barriers: a review of strategies for increasing drug deliveryQ34218914
CT and MRI of brain tumors.Q34278399
Ultrastructural pathology of endothelial tight junctions in human brain oedemaQ34330639
Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast CancerQ34393640
Molecular characterisation of cell line models for triple-negative breast cancersQ34476551
Drug resistance in epilepsy: the role of the blood-brain barrierQ34624873
Increased permeability of the blood-brain barrier to chemotherapy in metastatic brain tumors: establishing a treatment paradigmQ34632917
Inflammatory breast cancer (IBC): clues for targeted therapiesQ34754098
Blood-brain barrier breakdown in septic encephalopathy and brain tumoursQ34774036
Low-grade gliomas and leptomeningeal dissemination: a poorly understood phenomenonQ35102220
Understanding Heterogeneity and Permeability of Brain Metastases in Murine Models of HER2-Positive Breast Cancer Through Magnetic Resonance Imaging: Implications for Detection and TherapyQ35804288
NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancerQ35805489
Molecular mechanisms of brain tumor edemaQ35961516
In Vivo Magnetic Resonance Imaging for Investigating the Development and Distribution of Experimental Brain Metastases due to Breast CancerQ36061810
Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer.Q36371783
Characterization of the blood-brain barrier of metastatic and primary malignant neoplasms.Q36560327
Evidence for a causal role of parathyroid hormone-related protein in the pathogenesis of human breast cancer-mediated osteolysisQ37360238
Angiogenesis and anti-angiogenic molecularly targeted therapies in malignant gliomasQ37480527
Pericytes and vessel maturation during tumor angiogenesis and metastasisQ37764322
ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disordersQ37789041
Studies of human breast cancer metastasis using nude miceQ37912948
Neurovascular unit: a focus on pericytesQ37988811
Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulationQ38058856
Blood-brain barrier structure and function and the challenges for CNS drug deliveryQ38100970
CNS metastases in breast cancer: old challenge, new frontiersQ38168168
Novel insights into the development and maintenance of the blood-brain barrierQ38192912
Gliovascular and cytokine interactions modulate brain endothelial barrier in vitroQ40064513
Characterization of a novel cell line established from a patient with Herceptin-resistant breast cancer.Q40474432
Ultrastructure of capillary walls in human brain tumorsQ42493945
The role of eNOS in vascular permeability in ENU-induced gliomasQ43265274
The Brain Microenvironment and Cancer MetastasisQ43969265
Optimal visualization of multiple brain metastases for gamma knife radiosurgeryQ46085756
In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brainQ48401147
Opening the blood-brain and blood-tumor barriers in experimental rat brain tumors: the effect of intracarotid hyperosmolar mannitol on capillary permeability and blood flowQ48413486
Side by side comparison between dynamic versus static models of blood-brain barrier in vitro: a permeability studyQ48466858
The Susceptibility of Cerebral Endothelial Cells to Astroglial Induction of Blood-Brain Barrier Enzymes Depends on Their Proliferative StateQ48620210
In vivo characterization of changing blood-tumor barrier permeability in a mouse model of breast cancer metastasis: a complementary magnetic resonance imaging approach.Q49013289
Drug transport across the blood-brain barrierQ57677287
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)373-383
P577publication date2016-03-05
P1433published inClinical & Experimental MetastasisQ13470030
P1476titleCharacterization of passive permeability at the blood-tumor barrier in five preclinical models of brain metastases of breast cancer
P478volume33

Reverse relations

cites work (P2860)
Q38652516A mouse Model of Focal Vascular Injury Induces Astrocyte Reactivity, Tau Oligomers, and Aberrant Behavior.
Q39016244Advances in decoding breast cancer brain metastasis
Q47573654Drug delivery to melanoma brain metastases: Can current challenges lead to new opportunities?
Q91704255Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis
Q47839509Efficacy of T-DM1 for leptomeningeal and brain metastases in a HER2 positive metastatic breast cancer patient: new directions for systemic therapy - a case report and literature review
Q38953017Embracing rejection: Immunologic trends in brain metastasis
Q91796711Flaxseed Lignans as Important Dietary Polyphenols for Cancer Prevention and Treatment: Chemistry, Pharmacokinetics, and Molecular Targets
Q48108646Foe or friend? Janus-faces of the neurovascular unit in the formation of brain metastases
Q98938406HER2-positive breast cancer brain metastasis: A new and exciting landscape
Q58698483Heterogeneous distribution of trastuzumab in HER2-positive xenografts and metastases: role of the tumor microenvironment
Q45048012Identification of Novel Agents for the Treatment of Brain Metastases of Breast Cancer
Q92675544Improving CNS Delivery to Brain Metastases by Blood-Tumor Barrier Disruption
Q38720211In vivo magnetic resonance imaging investigating the development of experimental brain metastases due to triple negative breast cancer
Q54118354Investigational chemotherapy and novel pharmacokinetic mechanisms for the treatment of breast cancer brain metastases.
Q47549277Liposomal Irinotecan Accumulates in Metastatic Lesions, Crosses the Blood-Tumor Barrier (BTB), and Prolongs Survival in an Experimental Model of Brain Metastases of Triple Negative Breast Cancer
Q39330269Nanotherapeutic systems for local treatment of brain tumors
Q37602559Permeability across a novel microfluidic blood-tumor barrier model
Q59790152Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer
Q45046519Quantitative Fluorescence Microscopy Measures Vascular Pore Size in Primary and Metastatic Brain Tumors
Q52673453The Evolving Landscape of Brain Metastasis.

Search more.