Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition.

scientific article published on 21 November 2015

Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.6353
P932PMC publication ID4807996
P698PubMed publication ID26595802
P5875ResearchGate publication ID284713439

P50authorElda TagliabueQ39272222
Barbara OlivieroQ56754295
Andrea BalsariQ56999448
Tiziana TriulziQ57029188
Giulia Valeria BianchiQ58350763
P2093author name stringDaniele Generali
Stefania Varchetta
Gabriella Mariani
Lucia Sfondrini
Viola Regondi
Martina Di Modica
P2860cites workThe DNA damage pathway regulates innate immune system ligands of the NKG2D receptorQ24306696
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Neoadjuvant therapy with paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide chemotherapy and concurrent trastuzumab in human epidermal growth factor receptor 2-positive operable breast cancer: an update of the initial randomizedQ31089499
Adjuvant/neoadjuvant trastuzumab therapy in women with HER-2/neu-overexpressing breast cancer: a systematic reviewQ33337684
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Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant Trastuzumab Trial.Q35102480
Sequential versus concurrent trastuzumab in adjuvant chemotherapy for breast cancerQ35609706
Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancerQ35780315
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapyQ36108095
NK-cell and T-cell functions in patients with breast cancer: effects of surgery and adjuvant chemo- and radiotherapy.Q36608648
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NKG2D ligands in tumor immunityQ37287179
A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers.Q37418671
Understanding the mechanisms behind trastuzumab therapy for human epidermal growth factor receptor 2-positive breast cancerQ37626334
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Human breast tumor cells induce self-tolerance mechanisms to avoid NKG2D-mediated and DNAM-mediated NK cell recognitionQ39470152
Delivery of NKG2D ligand using an anti-HER2 antibody-NKG2D ligand fusion protein results in an enhanced innate and adaptive antitumor responseQ39619931
Shed HER2 extracellular domain in HER2-mediated tumor growth and in trastuzumab susceptibilityQ39699623
The anti-lymphoma effect of antibody-mediated immunotherapy is based on an increased degranulation of peripheral blood natural killer (NK) cellsQ40275203
A comparison of the in vitro and in vivo activities of IgG and F(ab')2 fragments of a mixture of three monoclonal anti-Her-2 antibodiesQ40552147
Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancerQ40554269
Neoadjuvant treatment with docetaxel and the effects of irradiation for human ovarian adenocarcinoma and cervical squamous cell carcinoma in vitroQ40747581
Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trialQ43951696
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancerQ45287928
Proteolytic release of soluble UL16-binding protein 2 from tumor cellsQ46970862
Elements Related to Heterogeneity of Antibody-Dependent Cell Cytotoxicity in Patients Under Trastuzumab Therapy for Primary Operable Breast Cancer Overexpressing Her2Q62604205
Pilot Study of the Mechanism of Action of Preoperative Trastuzumab in Patients with Primary Operable Breast Tumors Overexpressing HER2Q62604209
Inhibition of tumor-derived prostaglandin-e2 blocks the induction of myeloid-derived suppressor cells and recovers natural killer cell activityQ88035142
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)255-265
P577publication date2016-01-01
P1433published inOncotargetQ1573155
P1476titleTaxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition
P478volume7

Reverse relations

cites work (P2860)
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