Site-specific linking of biomolecules via glycan residues using glycosyltransferases

scientific article published on 22 April 2008

Site-specific linking of biomolecules via glycan residues using glycosyltransferases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1021/BP0704034
P932PMC publication ID2435414
P698PubMed publication ID18426242
P5875ResearchGate publication ID5427079

P2093author name stringBoopathy Ramakrishnan
Pradman K Qasba
Elizabeth Boeggeman
P2860cites workGlycosylation of recombinant antibody therapeuticsQ36132495
Drug-conjugated monoclonal antibodies for the treatment of cancerQ36222587
Antibody targeted drugs as cancer therapeuticsQ36373103
Mutant glycosyltransferases assist in the development of a targeted drug delivery system and contrast agents for MRIQ36439174
Therapeutic antibodies--delivering the promise?Q36528056
The impact of glycosylation on the biological function and structure of human immunoglobulins.Q36618276
The N-linked sugar chains of human immunoglobulin G: their unique pattern, and their functional rolesQ36894895
Further studies on the site-specific protein modification by microbial transglutaminaseQ40779928
A single point mutation reverses the donor specificity of human blood group B-synthesizing galactosyltransferaseQ44279217
A chemoenzymatic approach toward the rapid and sensitive detection of O-GlcNAc posttranslational modificationsQ44704206
In vitro galactosylation of human IgG at 1 kg scale using recombinant galactosyltransferaseQ46723270
Novel method for in vitro O-glycosylation of proteins: application for bioconjugationQ46937742
Tumor-Specific Novel Taxoid−Monoclonal Antibody ConjugatesQ59183296
Labeling of the oligosaccharide moieties of immunoglobulinsQ70179747
Development of potent monoclonal antibody auristatin conjugates for cancer therapyQ73460183
Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10)Q83227690
Dynamic association between the catalytic and lectin domains of human UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-2Q24301958
Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificityQ27638603
Click Chemistry: Diverse Chemical Function from a Few Good ReactionsQ28204398
Improving the efficacy of antibody-based cancer therapiesQ28208361
The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residuesQ28216354
Introducing genetically encoded aldehydes into proteinsQ28298867
Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase IQ28586071
Composition of N-linked carbohydrates from ovalbumin and co-purified glycoproteinsQ30654528
Direct identification of nonreducing GlcNAc residues on N-glycans of glycoproteins using a novel chemoenzymatic methodQ30830469
Species-specific variation in glycosylation of IgG: evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeuticsQ30857760
Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferasesQ33283045
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligationQ33896261
Arming antibodies: prospects and challenges for immunoconjugatesQ34449555
Targeted drug conjugates: principles and progressQ34455170
Engineered antibody fragments and the rise of single domainsQ34650980
Substrate-induced conformational changes in glycosyltransferasesQ36011052
Future directions of liposome- and immunoliposome-based cancer therapeuticsQ36045877
P433issue3
P304page(s)520-526
P577publication date2008-04-22
P1433published inBiotechnology ProgressQ15753227
P1476titleSite-specific linking of biomolecules via glycan residues using glycosyltransferases
P478volume24

Reverse relations

cites work (P2860)
Q33995843Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2007-2008.
Q36298206Bioconjugation and detection of lactosamine moiety using alpha1,3-galactosyltransferase mutants that transfer C2-modified galactose with a chemical handle
Q42105089Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry
Q34703755Improved synthesis of UDP-2-(2-ketopropyl)galactose and a first synthesis of UDP-2-(2-ketopropyl)glucose for the site-specific linking of biomolecules via modified glycan residues using glycosyltransferases
Q37405391Metabolic glycoengineering: sialic acid and beyond
Q36108943Multiple site-specific in vitro labeling of single-chain antibody
Q37403530Pretargeted PET Imaging Using a Site-Specifically Labeled Immunoconjugate
Q33441587Site specific conjugation of fluoroprobes to the remodeled Fc N-glycans of monoclonal antibodies using mutant glycosyltransferases: application for cell surface antigen detection
Q34803952The impact of enzyme engineering upon natural product glycodiversification