Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast

scientific article published on 6 March 2013

Intronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GAD.212738.112
P932PMC publication ID3613610
P698PubMed publication ID23468430
P5875ResearchGate publication ID235882490

P50authorPeter BaumannQ7172713
P2093author name stringJ Andrew Berglund
Jonathan P Staley
Ram Kannan
Rodger B Voelker
Sean Hartnett
P2860cites workGenome-wide association between branch point properties and alternative splicingQ21092523
Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factorQ24305953
Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distributionQ24310611
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase IIQ24338780
Evidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammalsQ24532589
An upstream AG determines whether a downstream AG is selected during catalytic step II of splicingQ24551016
Human branch point consensus sequence is yUnAyQ24646378
Promoter-driven splicing regulation in fission yeastQ59097207
Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicingQ64378031
The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNAQ67913244
Mutations in a yeast intron demonstrate the importance of specific conserved nucleotides for the two stages of nuclear mRNA splicingQ68864416
The organization of 3' splice-site sequences in mammalian intronsQ69452890
Formation of the 3' end of U1 snRNA requires compatible snRNA promoter elementsQ69638046
pDblet, a stable autonomously replicating shuttle vector for Schizosaccharomyces pombeQ71817989
Mutations in the SF1-U2AF59-U2AF23 complex cause exon skipping in Schizosaccharomyces pombeQ79386282
Effect of mutations at the lariat branch acceptor site on beta-globin pre-mRNA splicing in vitroQ93551289
The spliceosome: design principles of a dynamic RNP machineQ28131809
Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteinsQ29618943
Protection of telomeres by the Ku protein in fission yeastQ30306228
UACUAAC is the preferred branch site for mammalian mRNA splicingQ33850531
Yeast pre-messenger RNA splicing efficiency depends on critical spacing requirements between the branch point and 3' splice siteQ33879810
Spliceosome discards intermediates via the DEAH box ATPase Prp43pQ33933327
Semiquantitative proteomic analysis of the human spliceosome via a novel two-dimensional gel electrophoresis methodQ34181884
Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiaeQ34361753
DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic stepsQ34415414
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Identification and characterization of the Schizosaccharomyces pombe TER1 telomerase RNA.Q34586455
Functional analysis of the polypyrimidine tract in pre-mRNA splicingQ34625830
Both the polypyrimidine tract and the 3' splice site function prior to the first step of splicing in fission yeastQ34644631
A brief review of molecular information theory.Q35563841
Global analysis of mRNA decay intermediates in Saccharomyces cerevisiaeQ36122681
Eukaryotic Lsm proteins: lessons from bacteriaQ36331209
Exon ligation is proofread by the DExD/H-box ATPase Prp22pQ37059609
RNA splicing and intron turnover are greatly diminished by a mutant yeast branch pointQ37394068
Telomerase: an RNP enzyme synthesizes DNA.Q37775786
Staying on message: ensuring fidelity in pre-mRNA splicingQ38008056
Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23)Q39659121
TER1, the RNA subunit of fission yeast telomeraseQ39752449
Insights into branch nucleophile positioning and activation from an orthogonal pre-mRNA splicing system in yeastQ39978710
Fission yeast gene structure and recognitionQ40399675
The second catalytic step of pre-mRNA splicingQ40939314
Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexesQ41967731
Identification and comparative analysis of telomerase RNAs from Candida species reveal conservation of functional elementsQ42147960
A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zonesQ42148185
trans-splicing to spliceosomal U2 snRNA suggests disruption of branch site-U2 pairing during pre-mRNA splicingQ42381501
The role of branchpoint-3' splice site spacing and interaction between intron terminal nucleotides in 3' splice site selection in Saccharomyces cerevisiaeQ42611009
Ordered and dynamic assembly of single spliceosomesQ42726090
Competition between the ATPase Prp5 and branch region-U2 snRNA pairing modulates the fidelity of spliceosome assemblyQ43049651
A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing.Q44183759
Deciphering 3'ss selection in the yeast genome reveals an RNA thermosensor that mediates alternative splicingQ44838435
A U-rich tract enhances usage of an alternative 3′ splice site in yeastQ46196387
Cytoplasmic degradation of splice-defective pre-mRNAs and intermediatesQ47303263
Molecular cloning and characterization of the Schizosaccharomyces pombe his3 gene for use as a selectable markerQ48086234
U2AF homolog required for splicing in vivoQ48096653
Isolation of an active step I spliceosome and composition of its RNP coreQ50336090
Spliceosomal cleavage generates the 3' end of telomerase RNA.Q50336096
Repositioning of the reaction intermediate within the catalytic center of the spliceosome.Q52568800
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)627-638
P577publication date2013-03-06
P1433published inGenes & DevelopmentQ1524533
P1476titleIntronic sequence elements impede exon ligation and trigger a discard pathway that yields functional telomerase RNA in fission yeast
P478volume27

Reverse relations

cites work (P2860)
Q34988114Diverse mechanisms for spliceosome-mediated 3' end processing of telomerase RNA.
Q91956493Early splicing functions of fission yeast Prp16 and its unexpected requirement for gene Silencing is governed by intronic features
Q47201697Intron specificity in pre-mRNA splicing
Q39001197Large-scale analysis of branchpoint usage across species and cell lines
Q38123746Lives that introns lead after splicing
Q47184251New perspectives on telomerase RNA structure and function
Q35524345Non-mRNA 3' end formation: how the other half lives
Q39066545Peculiarities of Yeasts and Human Telomerase RNAs Processing
Q50106845Pof8 is a La-related protein and a constitutive component of telomerase in fission yeast
Q34987937Prevalent and distinct spliceosomal 3'-end processing mechanisms for fungal telomerase RNA.
Q92772490Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome
Q42845283Specific features of telomerase RNA from Hansenula polymorpha
Q37165431Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites
Q88571202Spliceosome Profiling Visualizes Operations of a Dynamic RNP at Nucleotide Resolution
Q42650602Spliceosome-mediated decay (SMD) regulates expression of nonintronic genes in budding yeast.
Q27008926Splicing fidelity: DEAD/H-box ATPases as molecular clocks
Q90316146Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6

Search more.