| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2008PNAS..105.8772Z |
| P356 | DOI | 10.1073/PNAS.0711355105 |
| P932 | PMC publication ID | 2438417 |
| P698 | PubMed publication ID | 18550843 |
| P5875 | ResearchGate publication ID | 5305875 |
| P2093 | author name string | Jie Zhang | |
| Li Wang | |||
| Yan Yang | |||
| Samantha A Cicero | |||
| Karl Herrup | |||
| Rita R Romito-Digiacomo | |||
| P2860 | cites work | Cell cycle regulation in the postmitotic neuron: oxymoron or new biology? | Q22337222 |
| The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner | Q24306574 | ||
| Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration | Q28140796 | ||
| Neurotoxicity induces cleavage of p35 to p25 by calpain | Q28145382 | ||
| Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation | Q28505942 | ||
| Cyclin-dependent kinase 5-deficient mice demonstrate novel developmental arrest in cerebral cortex | Q28509940 | ||
| Cdk5 is involved in neuregulin-induced AChR expression at the neuromuscular junction | Q28575776 | ||
| Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death | Q28576044 | ||
| Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death | Q28587075 | ||
| Neuronal cdc2-like kinase: a cdc2-related protein kinase with predominantly neuronal expression | Q33187332 | ||
| Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles | Q34279396 | ||
| Loss of neuronal cell cycle control in ataxia-telangiectasia: a unified disease mechanism. | Q34401594 | ||
| p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex | Q34666832 | ||
| Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype | Q35893635 | ||
| Coupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesis | Q36653014 | ||
| Abl deregulates Cdk5 kinase activity and subcellular localization in Drosophila neurodegeneration | Q40239614 | ||
| Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism | Q40412231 | ||
| Glucose-induced expression of the cyclin-dependent protein kinase 5 activator p35 involved in Alzheimer's disease regulates insulin gene transcription in pancreatic beta-cells | Q40587591 | ||
| Neuronal cdc2-like kinase | Q40605476 | ||
| Activity-dependent control of slow synaptic vesicle endocytosis by cyclin-dependent kinase 5. | Q40803584 | ||
| Beta-amyloid activated microglia induce cell cycling and cell death in cultured cortical neurons | Q40836274 | ||
| Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. | Q42439458 | ||
| DNA replication precedes neuronal cell death in Alzheimer's disease. | Q42502934 | ||
| Neocortical cell migration: GABAergic neurons and cells in layers I and VI move in a cyclin-dependent kinase 5-independent manner. | Q43819972 | ||
| Colocalization and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles | Q44032768 | ||
| A brain-specific activator of cyclin-dependent kinase 5. | Q48079027 | ||
| Alterations in beta-amyloid production and deposition in brain regions of two transgenic models | Q48242093 | ||
| DNA polymerase-beta is expressed early in neurons of Alzheimer's disease brain and is loaded into DNA replication forks in neurons challenged with beta-amyloid. | Q48387514 | ||
| Regional expression of key cell cycle proteins in brain from subjects with amnestic mild cognitive impairment | Q48411067 | ||
| Neuropathological characterization of mutant amyloid precursor protein yeast artificial chromosome transgenic mice | Q48691037 | ||
| Aberrant expression of mitotic cdc2/cyclin B1 kinase in degenerating neurons of Alzheimer's disease brain | Q48706959 | ||
| Interaction of cyclin-dependent kinase 5 (Cdk5) and neuronal Cdk5 activator in bovine brain. | Q49161768 | ||
| Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory. | Q50951137 | ||
| The induction of multiple cell cycle events precedes target-related neuronal death | Q52206831 | ||
| Mitotic signaling by beta-amyloid causes neuronal death | Q73263325 | ||
| E2F1 works as a cell cycle suppressor in mature neurons | Q79836147 | ||
| Cdk5 phosphorylates and stabilizes p27kip1 contributing to actin organization and cortical neuronal migration | Q81601109 | ||
| Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models | Q82297941 | ||
| P433 | issue | 25 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 8772-8777 | |
| P577 | publication date | 2008-06-12 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons | |
| P478 | volume | 105 |
| Q60917142 | ARNTL hypermethylation promotes tumorigenesis and inhibits cisplatin sensitivity by activating CDK5 transcription in nasopharyngeal carcinoma |
| Q36127961 | Achaete-scute homologue-1 (ASH1) stimulates migration of lung cancer cells through Cdk5/p35 pathway. |
| Q34525891 | CDK5 activator protein p25 preferentially binds and activates GSK3β |
| Q42121526 | CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death. |
| Q48381540 | Canonical TGF-β pathway activity is a predictor of SHH-driven medulloblastoma survival and delineates putative precursors in cerebellar development |
| Q37323185 | Cdk5 and the non-catalytic arrest of the neuronal cell cycle |
| Q38587949 | Cdk5 at crossroads of protein oligomerization in neurodegenerative diseases: facts and hypotheses |
| Q36122151 | Cdk5 levels oscillate during the neuronal cell cycle: Cdh1 ubiquitination triggers proteosome-dependent degradation during S-phase |
| Q33810194 | Cdk5 nuclear localization is p27-dependent in nerve cells: implications for cell cycle suppression and caspase-3 activation |
| Q39714708 | Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. |
| Q24299163 | Cdk5: multitasking between physiological and pathological conditions |
| Q49544319 | Cell Cycle Regulation in Treatment of Breast Cancer. |
| Q54738945 | Cell cycle activation and CNS injury. |
| Q35006482 | Cell cycle activation and spinal cord injury |
| Q34827354 | Cell cycle checkpoint abnormalities during dementia: A plausible association with the loss of protection against oxidative stress in Alzheimer's disease [corrected]. |
| Q24314465 | Cell cycle, CDKs and cancer: a changing paradigm |
| Q41790064 | Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics |
| Q33806924 | Contribution of nestin positive esophageal squamous cancer cells on malignant proliferation, apoptosis, and poor prognosis |
| Q34667041 | Cyclin I and p35 determine the subcellular distribution of Cdk5. |
| Q34654891 | Cyclin I is involved in the regulation of cell cycle progression |
| Q37599369 | Cyclin I-like (CCNI2) is a cyclin-dependent kinase 5 (CDK5) activator and is involved in cell cycle regulation |
| Q35126695 | Cyclin-dependent kinase 5 phosphorylation of familial prion protein mutants exacerbates conversion into amyloid structure |
| Q35925431 | Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons |
| Q64051857 | Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology and cognitive symptoms |
| Q46772855 | Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain |
| Q30424356 | Expression profiling reveals differential gene induction underlying specific and non-specific memory for pheromones in mice |
| Q26864155 | Extra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disorders |
| Q36234524 | Interplay between MEK-ERK signaling, cyclin D1, and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons |
| Q36746443 | Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease |
| Q37549786 | Loss of O-GlcNAc glycosylation in forebrain excitatory neurons induces neurodegeneration |
| Q37399885 | Making a neuron: Cdk5 in embryonic and adult neurogenesis. |
| Q28082139 | Mechanisms of HIV-1 Tat neurotoxicity via CDK5 translocation and hyper-activation: role in HIV-associated neurocognitive disorders |
| Q37261417 | MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons |
| Q41441508 | Mitosis-specific phosphorylation of amyloid precursor protein at threonine 668 leads to its altered processing and association with centrosomes |
| Q35006021 | Modulation of aberrant CDK5 signaling rescues impaired neurogenesis in models of Alzheimer's disease. |
| Q48633081 | Neuroprotective effects of Tongmai Yizhi Decoction () against Alzheimer's disease through attenuating cyclin-dependent kinase-5 expression |
| Q39307016 | New Functions of APC/C Ubiquitin Ligase in the Nervous System and Its Role in Alzheimer's Disease |
| Q54573588 | Nucleocytoplasmic transfer of cyclin dependent kinase 5 and its binding to puromycin-sensitive aminopeptidase in Dictyostelium discoideum. |
| Q36234835 | Phosphoregulation of the RNA-binding protein Hu antigen R (HuR) by Cdk5 affects centrosome function. |
| Q37349336 | Phosphorylation of prion protein at serine 43 induces prion protein conformational change |
| Q35085360 | Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. |
| Q92518340 | Physiological and pathological effects of amyloid-β species in neural stem cell biology |
| Q38140436 | Post-mitotic role of the cell cycle machinery |
| Q38103250 | Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function |
| Q26797972 | Prion-induced neurotoxicity: Possible role for cell cycle activity and DNA damage response |
| Q33787273 | Protein kinase Czeta regulates Cdk5/p25 signaling during myogenesis |
| Q34172616 | Recent progress in histochemistry and cell biology |
| Q35129037 | Regulation of Sox6 by cyclin dependent kinase 5 in brain |
| Q37992055 | Regulation of sirtuin function by posttranslational modifications |
| Q33769079 | Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease |
| Q45179815 | Scratch2 prevents cell cycle re-entry by repressing miR-25 in postmitotic primary neurons. |
| Q48215083 | Signaling via dopamine D1 and D3 receptors oppositely regulates cocaine-induced structural remodeling of dendrites and spines |
| Q89253294 | Spontaneous development of Alzheimer's disease-associated brain pathology in a Shugoshin-1 mouse cohesinopathy model |
| Q92651169 | The Anaphase Promoting Complex/Cyclosome (APC/C): A Versatile E3 Ubiquitin Ligase |
| Q91811038 | The Post-amyloid Era in Alzheimer's Disease: Trust Your Gut Feeling |
| Q38131284 | The cyclin-dependent kinase family in the social amoebozoan Dictyostelium discoideum |
| Q35775610 | The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation |
| Q36090948 | The roles of Cdk5-mediated subcellular localization of FOXO1 in neuronal death. |
| Q28082523 | Transcriptional control of stem cell fate by E2Fs and pocket proteins |
| Q37843832 | What's the hype about CDK5RAP2? |
| Q35349104 | p35 regulates the CRM1-dependent nucleocytoplasmic shuttling of nuclear hormone receptor coregulator-interacting factor 1 (NIF-1). |
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