The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases

scientific article published on 15 December 2015

The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3109/1354750X.2015.1123354
P932PMC publication ID4819811
P698PubMed publication ID26671823
P5875ResearchGate publication ID286927711

P2093author name stringFrancisca Lago
Oreste Gualillo
Ali Mobasheri
Juan J Gómez-Reino
Javier Conde
Jesús Pino
Morena Scotece
Rodolfo Gómez
Vanessa Abella
Ana Lois
P2860cites workNeutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current statusQ27015422
Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complexQ27662810
An iron delivery pathway mediated by a lipocalinQ28216116
A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin productionQ28511945
The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptakeQ28577988
A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptakeQ28587213
Inflammatory mechanisms in obesityQ29617932
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating ironQ29619561
Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse.Q30168651
The hydrophobic pocket of 24p3 protein from mouse uterine luminal fluid: fatty acid and retinol binding activity and predicted structural similarity to lipocalins.Q30175891
Emerging clinical and experimental evidence for the role of lipocalin-2 in metabolic syndrome.Q30404049
Lipocalin-2 regulates the inflammatory response during ischemia and reperfusion of the transplanted heart.Q33280256
Implication of granulocyte-macrophage colony-stimulating factor induced neutrophil gelatinase-associated lipocalin in pathogenesis of rheumatoid arthritis revealed by proteome analysisQ33596027
Lipocalin 2 expression and secretion is highly regulated by metabolic stress, cytokines, and nutrients in adipocytesQ33599979
Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesityQ33750720
Lipocalin-2 protein deficiency ameliorates experimental autoimmune encephalomyelitis: the pathogenic role of lipocalin-2 in the central nervous system and peripheral lymphoid tissuesQ33761191
Urinary neutrophil gelatinase-associated lipocalin as a novel biomarker for disease activity in lupus nephritisQ33785628
Lipocalin-2 deficiency impairs thermogenesis and potentiates diet-induced insulin resistance in miceQ33869748
Neutrophil gelatinase-associated lipocalin in normal and neoplastic human tissues. Cell type-specific pattern of expressionQ33873179
Iron at the interface of immunity and infectionQ33909430
Lipocalin 2 regulates brown fat activation via a nonadrenergic activation mechanismQ34070383
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Lipocalin 2 is a regulator of macrophage polarization and NF-κB/STAT3 pathway activationQ34265059
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammationQ34408108
Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans.Q34443257
Lipocalin 2 is a selective modulator of peroxisome proliferator-activated receptor-gamma activation and function in lipid homeostasis and energy expenditureQ34502676
Ischemic and nephrotoxic acute renal failure are distinguished by their broad transcriptomic responsesQ34771610
Neutrophil gelatinase-associated lipocalin increases HLA-G(+)/FoxP3(+) T-regulatory cell population in an in vitro model of PBMC.Q35107474
Lipocalin 2 deficiency alters estradiol production and estrogen receptor signaling in female miceQ35762647
The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma.Q35781827
A role of FcgammaRIIB in the development of collagen-induced arthritisQ35803207
Biologic basis of osteoarthritis: state of the evidenceQ35821610
Urinary neutrophil gelatinase-associated lipocalin is a potential biomarker for renal damage in patients with systemic lupus erythematosus.Q35830106
The multifaceted roles of neutrophil gelatinase associated lipocalin (NGAL) in inflammation and cancerQ35996059
Association of noninvasively measured renal protein biomarkers with histologic features of lupus nephritisQ36054578
Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis.Q36140013
Imbalance of regulatory T cells in human autoimmune diseasesQ36395703
NGAL (Lcn2) monomer is associated with tubulointerstitial damage in chronic kidney diseaseQ36458972
Neutrophil gelatinase-associated lipocalin, a siderophore-binding eukaryotic protein.Q36485689
Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in miceQ36745368
Adipokines as emerging mediators of immune response and inflammation.Q37014112
Neutrophil gelatinase-associated lipocalin (NGAL) as a marker of kidney damage.Q37251326
The induction of lipocalin-2 protein expression in vivo and in vitroQ37608519
What's new in our understanding of the role of adipokines in rheumatic diseases?Q37909903
Neutrophil gelatinase-associated lipocalin (NGAL): a promising biomarker of contrast-induced nephropathy after computed tomographyQ38199743
Nitric oxide boosts TLR-4 mediated lipocalin 2 expression in chondrocytes.Q39181948
Expanding the adipokine network in cartilage: identification and regulation of novel factors in human and murine chondrocytesQ39610428
Dexamethasone-induced expression of the glucocorticoid response gene lipocalin 2 in chondrocytes.Q39996123
Identification of common transcriptional regulatory elements in interleukin-17 target genesQ40263019
Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivationQ40788252
An apparent autocrine mechanism amplifies the dexamethasone- and retinoic acid-induced expression of mouse lipocalin-encoding gene 24p3.Q41199368
Cloning and expression of human neutrophil lipocalin cDNA derived from bone marrow and ovarian cancer cellsQ41381389
Molecular cloning, expression pattern analysis of porcine Rb1 gene and its regulatory roles during primary dedifferentiated fat cells adipogenic differentiationQ41519825
Lipocalin-2 is induced by interleukin-1beta in murine adipocytes in vitroQ42806370
The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistanceQ42826437
Lipocalin-2 controls the expression of SDF-1 and the number of responsive cells in boneQ43110806
Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosisQ45037418
A rapid plasma neutrophil gelatinase-associated lipocalin assay for diagnosis of acute pyelonephritis in infants with acute febrile urinary tract infections: a preliminary studyQ45326336
Proteomic characterization of mouse cartilage degradation in vitroQ46343368
Urinary neutrophil gelatinase-associated lipocalin as a marker of severe lupus nephritis in children.Q46489677
Neutrophil gelatinase-associated lipocalin is expressed in osteoarthritis and forms a complex with matrix metalloproteinase 9.Q46973399
Lipocalin 2 bolsters innate and adaptive immune responses to blood-stage malaria infection by reinforcing host iron metabolismQ48025739
Altered bone development and turnover in transgenic mice over-expressing lipocalin-2 in bone.Q51053901
Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance.Q51411287
Complement receptors 1 and 2 influence the immune environment in a B cell receptor-independent manner.Q53490602
Predictive role of urinary neutrophil gelatinase-associated lipocalin in lupus nephritis.Q53829835
Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans.Q54576196
Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophilsQ72749927
Ovarian steroids regulate 24p3 expression in mouse uterus during the natural estrous cycle and the preimplantation periodQ77968538
Identification of Neutrophil Gelatinase-Associated Lipocalin as a Novel Early Urinary Biomarker for Ischemic Renal InjuryQ79091417
Serum anti-lipocalin 2 IgG is a novel biomarker in the diagnosis of systemic lupus erythematosusQ87620615
Plasma neutrophil gelatinase-associated lipocalinin in the general population: association with inflammation and prognosisQ88164492
P433issue8
P921main subjectblood proteinsQ425056
biomarkerQ864574
transport proteinQ2111029
metabolic diseaseQ2351083
proto-oncogene proteinQ66020913
inflammation mediatorsQ66765004
neoplasm proteinQ66894191
P304page(s)565-571
P577publication date2015-12-15
P1433published inBiomarkersQ4915076
P1476titleThe potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases
P478volume20

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