scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1016/0167-5699(92)90198-G |
P953 | full work available at URL | https://api.elsevier.com/content/article/PII:016756999290198G?httpAccept=text/plain |
https://api.elsevier.com/content/article/PII:016756999290198G?httpAccept=text/xml | ||
P698 | PubMed publication ID | 1739426 |
P50 | author | Charles Janeway | Q1065040 |
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P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | immunology | Q101929 |
P304 | page(s) | 11-16 | |
P577 | publication date | 1992-01-01 | |
P1433 | published in | Trends in Immunology | Q15265730 |
P1476 | title | The immune system evolved to discriminate infectious nonself from noninfectious self | |
P478 | volume | 13 |
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Q90747011 | A philosophy of health: life as reality, health as a universal value |
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Q41924888 | A role for scavenger receptors in phagocytosis of protein-coated particles in rainbow trout head kidney macrophages. |
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Q47175712 | Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy |
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Q73449236 | An alkali-soluble factor present in normal brain tissue inhibits antigen-specific lymphocyte proliferation |
Q35823476 | An essential amino acid induces epithelial beta -defensin expression |
Q37866354 | An update on innate defense molecules of human gingiva |
Q38348817 | Animal lectins |
Q72792447 | Antibodies to proteins from Pityrosporum ovale in the sera from patients with psoriasis |
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Q58424608 | Churchill and the immune system of ectothermic vertebrates |
Q35881486 | Cleavage of PGRP-LC receptor in the Drosophila IMD pathway in response to live bacterial infection in S2 cells |
Q22010373 | Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D |
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Q36067103 | Combinatorial antibody libraries: new advances, new immunological insights |
Q37404751 | Comparative and developmental study of the immune system in Xenopus |
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Q36678496 | CpG DNA prevents liver injury and shock-mediated death by modulating expression of interleukin-1 receptor-associated kinases |
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Q36365206 | Dimerization of soluble major histocompatibility complex-peptide complexes is sufficient for activation of T cell hybridoma and induction of unresponsiveness |
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Q35809247 | Drosophila C-type lectins enhance cellular encapsulation |
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Q35749232 | Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium |
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Q40751217 | HCV: Written in our DNA. |
Q51091761 | HLA epitope based matching for transplantation. |
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Q35600716 | Oral microbial heat-shock proteins and their potential contributions to infections |
Q41326986 | Organ-specific autoimmunity induced by lymphopenia. |
Q44833305 | Origin of the interferon-inducible (2'-5')oligoadenylate synthetases: cloning of the (2'-5')oligoadenylate synthetase from the marine sponge Geodia cydonium |
Q35874571 | Outer membrane protein A (OmpA) of Shigella flexneri 2a links innate and adaptive immunity in a TLR2-dependent manner and involvement of IL-12 and nitric oxide |
Q85530493 | PATHOLOGICAL ASPECTS OF THE ANTI-INFLAMMATORY/IMMUNE SUPPRESSIVE RESPONSE IN SEPSIS AND SHOCK |
Q33915855 | Passive or active immunization with myelin basic protein promotes recovery from spinal cord contusion. |
Q38228956 | Pattern recognition receptors and central nervous system repair. |
Q37761827 | Periodontitis: a polymicrobial disruption of host homeostasis |
Q36381014 | Persistence of peptide-induced CD4+ T cell anergy in vitro |
Q24798199 | Phylogenetic variation and polymorphism at the toll-like receptor 4 locus (TLR4) |
Q34659528 | Plasma RANTES, IL-10, and IL-8 levels in non-small-cell lung cancer patients treated with EGFR-TKIs. |
Q57676574 | Platelet immunobiology: platelets as prey and predator |
Q47381141 | Platelets Toll-like receptor-4 in Crohns disease |
Q37657202 | Platelets and innate immunity |
Q37857647 | Platelets and the immune continuum |
Q24798836 | Polymorphism in clinical immunology - From HLA typing to immunogenetic profiling |
Q23923013 | Polymorphisms in the CD14 gene associated with pulmonary function in farmers |
Q57952426 | Porin of Shigella dysenteriae enhances Toll-like receptors 2 and 6 of mouse peritoneal B-2 cells and induces the expression of immunoglobulin M, immunoglobulin G2a and immunoglobulin A |
Q54739900 | Porin of Shigella dysenteriae enhances mRNA levels for Toll-like receptor 2 and MyD88, up-regulates CD80 of murine macrophage, and induces the release of interleukin-12. |
Q40014914 | Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. |
Q40398318 | Porphyromonas gingivalis lipopolysaccharide displays functionally diverse interactions with the innate host defense system |
Q34120648 | Porphyromonas gingivalis lipopolysaccharide is both agonist and antagonist for p38 mitogen-activated protein kinase activation |
Q99238024 | Porphyromonas gingivalis-Induced NLRP3 Inflammasome Activation and Its Downstream Interleukin-1β Release Depend on Caspase-4 |
Q34008791 | Potent stimulation of the innate immune system by a Leishmania brasiliensis recombinant protein |
Q37700561 | Potential of the beta-glucans to enhance innate resistance to biological agents |
Q24646220 | Preeclampsia: a view through the danger model |
Q35037363 | Primary prevention of uterine cervix cancer: focus on vaccine history and current strategy |
Q36735401 | Primer: comparative genetics of animal models of arthritis--a tool to resolve complexity |
Q34937622 | Programming for responsiveness to environmental antigens that trigger allergic respiratory disease in adulthood is initiated during the perinatal period |
Q35084902 | Protection against experimental autoimmune myocarditis is mediated by interleukin-10-producing T cells that are controlled by dendritic cells |
Q37651354 | Protein bio-corona: critical issue in immune nanotoxicology |
Q41392031 | Purification and characterization of a human membrane protein that activates the alternative complement pathway and allows the deposition of homologous complement C3. |
Q36268500 | Quantitative rules for lymphocyte regulation: the cellular calculus and decisions between tolerance and activation. |
Q36363011 | Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces |
Q33813643 | Rare antibodies from combinatorial libraries suggests an S.O.S. component of the human immunological repertoire |
Q37766262 | Recent insights into the role of Toll-like receptors in viral infection |
Q37559669 | Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins. |
Q24530569 | Recognition of Staphylococcus aureus by the innate immune system |
Q37193505 | Recognition of non-self-polysaccharides by C-type lectin receptors dectin-1 and dectin-2. |
Q38357758 | Recombinant bovine conglutinin, lacking the N-terminal and collagenous domains, has less conglutination activity but is able to inhibit haemagglutination by influenza A virus |
Q28250469 | Reflections on the clonal-selection theory |
Q34497326 | Regulated gene expression in gene therapy. |
Q45112156 | Regulation of adaptive immunity by natural killer cells |
Q36380889 | Regulation of experimental autoimmune encephalomyelitis by natural killer (NK) cells |
Q36848047 | Resistance of MMP9 and TIMP1 to endotoxin tolerance |
Q37810600 | Respective roles of TLR, RIG-I and NLRP3 in influenza virus infection and immunity: impact on vaccine design |
Q36401161 | Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity |
Q41399593 | Review: Peyer's patches |
Q64996238 | Ribosomal DNA as DAMPs Signal for MCF7 Cancer Cells. |
Q25257758 | Role of TOLL-like Receptors in Adjuvant-Augmented Immune Therapies by T. Seya |
Q36404683 | Role of antigen-presenting cells in mediating tolerance and autoimmunity |
Q37754716 | Role of bacterial infections in allograft rejection |
Q36439187 | Role of bioactivation in drug-induced hypersensitivity reactions |
Q36404148 | Role of the integument in insect immunity: epicuticular abrasion and induction of cecropin synthesis in cuticular epithelial cells |
Q36703949 | Roles of receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoprotegerin in periodontal health and disease |
Q47620008 | STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum. |
Q71320499 | Scavenger receptors in innate immunity |
Q38419969 | Sequential Immune Responses: The Weapons of Immunity |
Q77488329 | Shifting T-cell activation thresholds in autoimmunity and determinant spreading |
Q33907293 | Shifts in the epitopes of myelin basic protein recognized by Lewis rat T cells before, during, and after the induction of experimental autoimmune encephalomyelitis |
Q34590044 | Sialoside-based pattern recognitions discriminating infections from tissue injuries |
Q33974526 | Siglec-G/10 in self-nonself discrimination of innate and adaptive immunity. |
Q36325327 | Some reasons why deletion and anergy do not satisfactorily account for natural tolerance |
Q39825128 | Specific role of phosphoinositide 3-kinase p110alpha in the regulation of phagocytosis and pinocytosis in macrophages |
Q47135720 | Strategies to Improve the Efficacy of Dendritic Cell-Based Immunotherapy for Melanoma |
Q36113326 | Stress and immunological recognition in host-pathogen interactions |
Q27648579 | Structural basis for innate immune sensing by M-ficolin and its control by a pH-dependent conformational switch |
Q24682124 | Structural insights into the innate immune recognition specificities of L- and H-ficolins |
Q27733853 | Structure of the complex between human T-cell receptor, viral peptide and HLA-A2 |
Q40903248 | Structure-function analysis of CD14 as a soluble receptor for lipopolysaccharide |
Q39510867 | Structures in Bacillus subtilis are recognized by CD14 in a lipopolysaccharide binding protein-dependent reaction |
Q52589937 | Surface characteristics of foreign targets that elicit an encapsulation response by the moth Pseudoplusia includens. |
Q82570932 | Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing |
Q35192171 | Survey of human-use adjuvants |
Q28005535 | Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy |
Q43511256 | T Cell Receptor Binding to a pMHCII Ligand Is Kinetically Distinct from and Independent of CD4. |
Q36363017 | T cell costimulation by B7/BB1 induces CD8 T cell-dependent tumor rejection: an important role of B7/BB1 in the induction, recruitment, and effector function of antitumor T cells. |
Q48238886 | T cell responses to tumor: how dominant assumptions on immune activity led to a neglect of pathological functions, and how evolutionary considerations can help identify testable hypotheses for improving immunotherapy. |
Q43774330 | T cell tolerance and self/nonself discrimination |
Q58793668 | T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells |
Q34171890 | T cell-macrophage interactions and granuloma formation in vasculitis. |
Q40746119 | T cells and thyroid autoimmunity. |
Q51913407 | T cells survey the stability of the self: a testable hypothesis on the homeostatic role of TCR-MHC interactions. |
Q36997273 | T lymphocytes in Sjögren's syndrome: contributors to and regulators of pathophysiology |
Q37257085 | TLR4 polymorphism and periodontitis susceptibility: A meta-analysis |
Q79324702 | TLR5 takes aim at bacterial propeller |
Q35593328 | TLRs and NODs mRNA expression pattern in healthy mouse eye. |
Q80504764 | TLRs in disease |
Q24310057 | TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain |
Q74268258 | Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis |
Q34807615 | Targeting cancer's weaknesses (not its strengths): Therapeutic strategies suggested by the atavistic model |
Q36041765 | Temporal and spatial expression of high-mobility group box 1 in surgically injured rat vocal folds |
Q33833220 | Th1/Th2 balance in infection |
Q81397226 | Th1/Th2 polarization by viral and helminth infection in birds |
Q36371212 | The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens |
Q40776029 | The Caenorhabditis elegans p38 MAPK Gene plays a key role in protection from mycobacteria |
Q74696144 | The Clonal Selection Theory: what it really is and why modern challenges are misplaced |
Q40147137 | The Immune Adjuvant Effects of Flounder (Paralichthys olivaceus) Interleukin-6 on E. tarda Subunit Vaccine OmpV. |
Q64276875 | The Interplay between Immunity and Microbiota at Intestinal Immunological Niche: The Case of Cancer |
Q40635862 | The Lip lipoprotein from Neisseria gonorrhoeae stimulates cytokine release and NF-kappaB activation in epithelial cells in a Toll-like receptor 2-dependent manner. |
Q89127025 | The Neuro-Immune-Regulators (NIREGs) Promote Tissue Resilience; a Vital Component of the Host's Defense Strategy against Neuroinflammation |
Q38880688 | The Role of Proinflammatory Cytokine Interleukin-18 in Radiation Injury |
Q40151249 | The Role of the Immune System Beyond the Fight Against Infection. |
Q46194843 | The Thymus/Neocortex Hypothesis of the Brain: A Cell Basis for Recognition and Instruction of Self. |
Q26859223 | The activation and inactivation of mature CD4 T cells: a case for peripheral self-nonself discrimination |
Q44991707 | The adaptation model of immunity |
Q37685453 | The alarmin functions of high-mobility group proteins. |
Q37943469 | The antibody response to an HLA mismatch: a model for nonself-self discrimination in relation to HLA epitope immunogenicity |
Q40511561 | The basis of autoimmunity: an overview |
Q37008661 | The biological role of dectin-1 in immune response |
Q33922391 | The biology of Toll-like receptors |
Q21131221 | The danger theory: 20 years later |
Q28384138 | The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity |
Q34012447 | The development of the immune system during pregnancy and early life |
Q27001581 | The effects of TLR activation on T-cell development and differentiation |
Q38165257 | The emerging role of the receptor for advanced glycation end products on innate immunity |
Q36407199 | The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity |
Q34573771 | The enemy within: keeping self-reactive T cells at bay in the periphery |
Q59564566 | The evolution of self-tolerance: a new cell arises to meet the challenge of self-reactivity |
Q34207060 | The evolutionary context for a self-nonself discrimination |
Q92065855 | The history of the two-signal model of lymphocyte activation: A personal perspective |
Q28243940 | The human beta-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells |
Q46378486 | The human macrophage mannose receptor is not a professional phagocytic receptor |
Q73983474 | The immune system's role in graft loss: theoretic considerations |
Q42035149 | The immunoglobulin family protein Hemolin mediates cellular immune responses to bacteria in the insect Manduca sexta |
Q35687958 | The immunological paradox of pregnancy: a reappraisal |
Q82182732 | The impact of CD14 polymorphisms on the development of soluble CD14 levels during infancy |
Q33732470 | The innate immune system in allograft rejection and tolerance |
Q34282306 | The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics |
Q33887468 | The macrophage receptor MARCO. |
Q36380853 | The macrophage scavenger receptor type A is expressed by activated macrophages and protects the host against lethal endotoxic shock |
Q28266161 | The mannose receptor is a pattern recognition receptor involved in host defense |
Q36348036 | The mannose-binding lectin: a prototypic pattern recognition molecule |
Q34502370 | The many roles of the class A macrophage scavenger receptor |
Q41754941 | The microbial challenge in periodontitis |
Q38116712 | The multifunctional alarmin HMGB1 with roles in the pathophysiology of sepsis and cancer |
Q37478630 | The oral microbial consortium's interaction with the periodontal innate defense system |
Q40872998 | The pathobiology of peritonitis |
Q74187442 | The primary IgM antibody repertoire: a source of potent idiotype immunogens |
Q80038678 | The promise of cancer vaccines |
Q24803143 | The quantal theory of how the immune system discriminates between "self and non-self" |
Q33599759 | The regulation of apoptosis by microbial pathogens. |
Q38750747 | The regulatory isoform rPGRP-LC induces immune resolution via endosomal degradation of receptors |
Q28512624 | The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors |
Q43895324 | The role of advanced oxidation protein products in regulation of dendritic cell function |
Q26851880 | The role of mannose-binding lectin in severe sepsis and septic shock |
Q37784863 | The roles of TNF in brain dysfunction and disease |
Q41326875 | The significance of immune suppression in normal self tolerance |
Q48291060 | The small heat shock protein alpha B-crystallin as key autoantigen in multiple sclerosis |
Q42233804 | The teleost acute-phase inflammatory response and caspase activation by a novel alarmin-like ligand |
Q40838120 | The thymus and T-cell tolerance |
Q77846814 | The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS |
Q26863283 | Therapeutic cancer vaccines: past, present, and future |
Q38270021 | Thoughts engendered by Bretscher's Two-step, Two-signal model for a peripheral self-non-self discrimination and the origin of primer effector T helpers |
Q37638199 | Tissue-mediated control of immunopathology in coeliac disease |
Q33840545 | Tlr4: central component of the sole mammalian LPS sensor |
Q26866038 | To drive or be driven: the path of a mouse model of recurrent pregnancy loss |
Q33919388 | Tolerance and hematopoietic stem cell transplantation 50 years after Burnet's theory |
Q70823350 | Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD) |
Q24300611 | Toll IL-1 receptors differ in their ability to promote the stabilization of adenosine and uridine-rich elements containing mRNA |
Q34537817 | Toll receptors: a central element in innate immune responses |
Q34026903 | Toll signaling: the enigma variations |
Q55033421 | Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. |
Q38928359 | Toll-like receptor 3 (TLR3) signaling requires TLR4 Interactor with leucine-rich REPeats (TRIL). |
Q51692419 | Toll-like receptor-4 is involved in eliciting an LPS-induced oxidative burst in neutrophils. |
Q29615458 | Toll-like receptors and innate immunity |
Q34296477 | Toll-like receptors and innate immunity. |
Q34932177 | Toll-like receptors as potential therapeutic targets for multiple diseases |
Q37779740 | Toll-like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: towards future therapeutic application |
Q53687316 | Toll-like receptors in immunity and inflammatory diseases: Past, present, and future. |
Q27486231 | Toll-like receptors regulation of viral infection and disease☆ |
Q38140711 | Toll-like receptors' pathway disturbances are associated with increased susceptibility to infections in humans |
Q37705431 | Towards a liquid self: how time, geography, and life experiences reshape the biological identity |
Q51898265 | Towards understanding the immune system. |
Q35090683 | Trauma is danger |
Q37223201 | Treatment with recombinant human bone morphogenetic protein 7 leads to a transient induction of neutralizing autoantibodies in a subset of patients. |
Q37867107 | Trends in vaccine adjuvants. |
Q34626956 | Tumor antigen-dependent and tumor antigen-independent activation of antitumor activity in T cells by a bispecific antibody-modified tumor vaccine |
Q36171257 | Tweaking Innate Immunity: the Promise of Innate Immunologicals As Anti-infectives |
Q41472307 | Unravelling the mast cell dilemma: culprit or victim of its generosity? |
Q35646594 | Usefulness of the Nonself-Self Algorithm of HLA Epitope Immunogenicity in the Specificity Analysis of Monospecific Antibodies Induced during Pregnancy |
Q37119041 | Using innate immunity to characterize the host response to microbial invasion in severe sepsis |
Q30901141 | V genes in primates from whole genome sequencing data. |
Q35192218 | Vaccine adjuvant technology: from mechanistic concepts to practical applications |
Q36959938 | Vaccine immunopotentiators of the future |
Q36638343 | Venom of Parasitoid Pteromalus puparum Impairs Host Humoral Antimicrobial Activity by Decreasing Host Cecropin and Lysozyme Gene Expression |
Q34064782 | Venom of parasitoid, Pteromalus puparum, suppresses host, Pieris rapae, immune promotion by decreasing host C-type lectin gene expression |
Q84926012 | What is so special about thinking; after all, we all do it! |
Q34627005 | What is the 'true' function of skin? |
Q37227956 | What roles do regulatory T cells play in the control of the adaptive immune response? |
Q36762514 | When three is not a crowd: a Crossregulation model of the dynamics and repertoire selection of regulatory CD4+ T cells. |
Q33544032 | Why are dendritic cells central to cancer immunotherapy? |
Q47975133 | Xenogeneic skin graft rejection in M‐CSF/macrophage deficient osteopetrotic mice |
Q57258278 | poly(I:C) and LPS induce distinct IRF3 and NF-κB signaling during type-I IFN and TNF responses in human macrophages |
Q58385453 | γδ T cells provide a breath of fresh air for asthma research |
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