scholarly article | Q13442814 |
P50 | author | Dhivya R Sudhan | Q85954937 |
Erica N Parker | Q86476571 | ||
Kevin G. Pinney | Q39948043 | ||
Michael R. Horsman | Q47792821 | ||
P2093 | author name string | Amanda K Charlton-Sevcik | |
David J Chaplin | |||
G D Kishore Kumar | |||
Gustavo E Chavarria | |||
Mary Lynn Trawick | |||
Tracy E Strecker | |||
Jiangli Song | |||
Dietmar W Siemann | |||
Thomas R Wittenborn | |||
Samuel O Odutola | |||
Ashleigh L Barnes | |||
P2860 | cites work | A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes | Q24647928 |
Dipeptidyl nitrile inhibitors of Cathepsin L | Q27655858 | ||
Systematic investigation of halogen bonding in protein-ligand interactions | Q27666413 | ||
Cathepsin B, Cathepsin H, and cathepsin L | Q28277583 | ||
Identification of semicarbazones, thiosemicarbazones and triazine nitriles as inhibitors of Leishmania mexicana cysteine protease CPB | Q28534433 | ||
New colorimetric cytotoxicity assay for anticancer-drug screening | Q29615418 | ||
Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. | Q31805262 | ||
Synthesis and structure-activity relationships of parasiticidal thiosemicarbazone cysteine protease inhibitors against Plasmodium falciparum, Trypanosoma brucei, and Trypanosoma cruzi | Q33203203 | ||
Substrate profiling of cysteine proteases using a combinatorial peptide library identifies functionally unique specificities | Q33235638 | ||
Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors | Q33525418 | ||
Synthesis and biochemical evaluation of thiochromanone thiosemicarbazone analogues as inhibitors of cathepsin L. | Q33630596 | ||
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K. | Q34009651 | ||
A small-molecule oxocarbazate inhibitor of human cathepsin L blocks severe acute respiratory syndrome and ebola pseudotype virus infection into human embryonic kidney 293T cells. | Q34051627 | ||
Identification of lead compounds targeting the cathepsin B-like enzyme of Eimeria tenella | Q34092125 | ||
Rethinking smallpox | Q34373302 | ||
Sulforhodamine B colorimetric assay for cytotoxicity screening. | Q51032435 | ||
Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas' disease | Q58845224 | ||
Thiosemicarbazones derived from 1-indanones as new anti-Trypanosoma cruzi agents | Q58869711 | ||
Synthesis and Photochromism of Novel Phenylene-Linked Photochromic Bispyrans | Q64168913 | ||
"In vitro" study of basement membrane degradation by the cysteine proteinases, cathepsins B, B-like and L. Digestion of collagen IV, laminin, fibronectin, and release of gelatinase activities from basement membrane fibronectin. | Q64932386 | ||
Susceptibility of the cartilage collagens types II, IX and XI to degradation by the cysteine proteinases, cathepsins B and L | Q68889511 | ||
Investigations on the possibility of a thermic tumour therapy. I. Short-wave treatment of a transplanted isologous mouse mammary carcinoma | Q70340732 | ||
Clinical experience with the antiviral drug marboran (1-methylisatin 3-thiosemicarbazone) | Q71169083 | ||
Simultaneous and sequential hyperthermia and radiation treatment of an experimental tumor and its surrounding normal tissue in vivo | Q71478988 | ||
Prophylaxis of smallpox with methisazone | Q72439965 | ||
Generation of matrix-degrading proteolytic system from fibronectin by cathepsins B, G, H and L | Q72608575 | ||
Structure based development of novel specific inhibitors for cathepsin L and cathepsin S in vitro and in vivo | Q73077056 | ||
Combretastatins novel vascular targeting drugs for improving anti-cancer therapy. Combretastatins and conventional therapy | Q74193362 | ||
The collagenolytic activity of cathepsin K is unique among mammalian proteinases | Q77581104 | ||
Formal intramolecular photoredox chemistry of meta-substituted benzophenones | Q80375422 | ||
Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer | Q80726283 | ||
Structural optimization of azadipeptide nitriles strongly increases association rates and allows the development of selective cathepsin inhibitors | Q82722803 | ||
Preparation and ESR detection of a ground-state nonet hydrocarbon as a model for one-dimensional organic ferromagnets | Q82993421 | ||
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis | Q34471105 | ||
Initial evaluation of the antitumour activity of KGP94, a functionalized benzophenone thiosemicarbazone inhibitor of cathepsin L. | Q34483740 | ||
Cysteine cathepsins and the cutting edge of cancer invasion | Q34605340 | ||
Multiplex zymography captures stage-specific activity profiles of cathepsins K, L, and S in human breast, lung, and cervical cancer | Q35137318 | ||
Therapeutic targets for bone metastases in breast cancer | Q35558919 | ||
Cysteine proteases as disease markers | Q35693690 | ||
Cysteine cathepsins: multifunctional enzymes in cancer | Q36600996 | ||
Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics--results from single oral dose studies in healthy volunteers. | Q36792968 | ||
Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model. | Q37270829 | ||
Acid-mediated tumor proteolysis: contribution of cysteine cathepsins | Q37285534 | ||
Cathepsin L inhibition by the small molecule KGP94 suppresses tumor microenvironment enhanced metastasis associated cell functions of prostate and breast cancer cells | Q37296811 | ||
The footprints of cancer development: Cancer biomarkers | Q37343214 | ||
Proteolytic networks in cancer | Q37343319 | ||
The marine cyanobacterial metabolite gallinamide A is a potent and selective inhibitor of human cathepsin L. | Q37598633 | ||
Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3'-hydroxy-4'-methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-methoxyindole (OXi8006) | Q37626788 | ||
Cathepsin L, target in cancer treatment? | Q37643875 | ||
Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis | Q37783433 | ||
Cysteine cathepsins and extracellular matrix degradation. | Q38200374 | ||
Development of a highly potent, selective, and cell-active inhibitor of cysteine cathepsin L-A hybrid design approach. | Q38969005 | ||
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB | Q39412077 | ||
Functional imaging of proteolysis: stromal and inflammatory cells increase tumor proteolysis | Q40612550 | ||
Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines | Q41679901 | ||
Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues | Q41849893 | ||
Design, synthesis and anti-plasmodial evaluation in vitro of new 4-aminoquinoline isatin derivatives | Q41912478 | ||
Action of rat liver cathepsin L on collagen and other substrates | Q42167985 | ||
Synthesis and antimalarial activity of novel dihydro-artemisinin derivatives. | Q42733212 | ||
The cathepsin K inhibitor odanacatib suppresses bone resorption in women with breast cancer and established bone metastases: results of a 4-week, double-blind, randomized, controlled trial | Q42781348 | ||
A rapid in vitro assay for quantitating the invasive potential of tumor cells | Q42807739 | ||
Isolation and characterization of PC-3 human prostatic tumor sublines which preferentially metastasize to select organs in S.C.I.D. mice | Q42808290 | ||
Procathepsin L degrades extracellular matrix proteins in the presence of glycosaminoglycans in vitro | Q42819271 | ||
Functionalized benzophenone, thiophene, pyridine, and fluorene thiosemicarbazone derivatives as inhibitors of cathepsin L. | Q42864053 | ||
Mechanisms of acid-catalyzed Z/E isomerization of imines | Q43808314 | ||
Synthesis and structure-activity relationship study of potent trypanocidal thio semicarbazone inhibitors of the trypanosomal cysteine protease cruzain | Q44025532 | ||
Expression of cysteine peptidase cathepsin L and its inhibitors stefins A and B in relation to tumorigenicity of breast cancer cell lines | Q44164221 | ||
Small-molecule inhibitors of cathepsin L incorporating functionalized ring-fused molecular frameworks. | Q44440055 | ||
Efficient synthetic method for ethyl (+)-(2S,3S)-3-[(S)-3-methyl- 1-(3-methylbutylcarbamoyl)butylcarbamoyl]-2-oxiranecarb oxylate (EST), a new inhibitor of cysteine proteinases | Q45004042 | ||
Azepanone-based inhibitors of human cathepsin L. | Q46775748 | ||
P433 | issue | 21 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 6974-6992 | |
P577 | publication date | 2015-09-25 | |
P1433 | published in | Bioorganic & Medicinal Chemistry | Q2904200 |
P1476 | title | Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L | |
P478 | volume | 23 |
Q89634052 | A Review of Small Molecule Inhibitors and Functional Probes of Human Cathepsin L |
Q92702993 | A Review of the Structure-Activity Relationship of Natural and Synthetic Antimetastatic Compounds |
Q90355647 | Cathepsin L secretion by host and neoplastic cells potentiates invasion |
Q48332154 | Hydrazone Derivatives Enhance Antileishmanial Activity of Thiochroman-4-ones. |
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