Effects of minocycline plus tissue plasminogen activator combination therapy after focal embolic stroke in type 1 diabetic rats

scientific article published on 19 February 2013

Effects of minocycline plus tissue plasminogen activator combination therapy after focal embolic stroke in type 1 diabetic rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/STROKEAHA.111.000309
P932PMC publication ID3632085
P698PubMed publication ID23422086

P2093author name stringEng H Lo
Xiaoying Wang
Xiang Fan
P2860cites workDelayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental strokeQ28569418
Laser Doppler flowmetry predicts occlusion but not tPA-mediated reperfusion success after rat embolic strokeQ33387740
A rat model of studying tissue-type plasminogen activator thrombolysis in ischemic stroke with diabetesQ34066733
Annexin A2 combined with low-dose tPA improves thrombolytic therapy in a rat model of focal embolic stroke.Q34171180
Vascular protection in diabetic stroke: role of matrix metalloprotease-dependent vascular remodelingQ34410352
Minocycline inhibits 5-lipoxygenase activation and brain inflammation after focal cerebral ischemia in ratsQ34579572
Minocycline treatment in acute stroke: an open-label, evaluator-blinded study.Q34696376
Prospects for minocycline neuroprotectionQ35079515
Brain inflammation is induced by co-morbidities and risk factors for strokeQ35132428
Minocycline development for acute ischemic strokeQ35202559
Neurovascular injury in acute hyperglycemia and diabetes: A comparative analysis in experimental strokeQ35202882
Minocycline-induced attenuation of iron overload and brain injury after experimental intracerebral hemorrhageQ35581074
Mechanisms of hemorrhagic transformation after tissue plasminogen activator reperfusion therapy for ischemic strokeQ35905986
The promise of minocycline in neurology.Q35958974
Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by Increasing superoxide productionQ36010304
A rat model of focal embolic cerebral ischemiaQ36889748
Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in ratsQ37017515
Admission hyperglycemia predicts a worse outcome in stroke patients treated with intravenous thrombolysisQ37139530
Neutrophils contribute to intracerebral haemorrhages after treatment with recombinant tissue plasminogen activator following cerebral ischaemiaQ37230709
Targeting extracellular matrix proteolysis for hemorrhagic complications of tPA stroke therapyQ37232887
Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potentialQ37367536
Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complicationsQ37512877
Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding studyQ37562665
Clinical pharmacokinetics of doxycycline and minocyclineQ39571569
Baseline diabetic status and admission blood glucose were poor prognostic factors in the EPITHET trial.Q39932002
Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke.Q40607050
Extension of the thrombolytic time window with minocycline in experimental stroke.Q41812595
Repurposing an old drug to improve the use and safety of tissue plasminogen activator for acute ischemic stroke: minocyclineQ41847547
MMP-mediated disruption of claudin-5 in the blood-brain barrier of rat brain after cerebral ischemiaQ42413334
Liquid chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat.Q44472506
Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release.Q44647403
Impact of admission hyperglycemia on stroke outcome after thrombolysis: risk stratification in relation to time to reperfusion.Q45096508
Minocycline protects against permanent cerebral ischemia in wild type but not in matrix metalloprotease-9-deficient miceQ45240483
Chronic treatment with minocycline preserves adult new neurons and reduces functional impairment after focal cerebral ischemiaQ46253405
Role of matrix metalloproteinases in delayed cortical responses after strokeQ48604373
Intracerebral hemorrhage after intravenous t-PA therapy for ischemic stroke. The NINDS t-PA Stroke Study GroupQ73877940
Minocycline attenuates the development of diabetic neuropathic pain: possible anti-inflammatory and anti-oxidant mechanismsQ84016180
Exaggerated neutrophil-mediated reperfusion injury after ischemic stroke in a rodent model of type 2 diabetesQ84431634
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectminocyclineQ415336
plasminogenQ107129060
embolic strokeQ107538662
P304page(s)745-752
P577publication date2013-02-19
P1433published inStroke JournalQ7624282
P1476titleEffects of minocycline plus tissue plasminogen activator combination therapy after focal embolic stroke in type 1 diabetic rats
P478volume44

Reverse relations

cites work (P2860)
Q50602045Annexin A2 Plus Low-Dose Tissue Plasminogen Activator Combination Attenuates Cerebrovascular Dysfunction After Focal Embolic Stroke of Rats.
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Q40143778Autophagy Promotes Microglia Activation Through Beclin-1-Atg5 Pathway in Intracerebral Hemorrhage
Q99238065Blood-Brain Barrier: More Contributor to Disruption of Central Nervous System Homeostasis Than Victim in Neurological Disorders
Q38688253Clot injection technique affects thrombolytic efficacy in a rat embolic stroke model: implications for translaboratory collaborations.
Q35587581Comparative Analysis of Different Methods of Ischemia/Reperfusion in Hyperglycemic Stroke Outcomes: Interaction with tPA.
Q52691666Danhong Injection Combined With t-PA Improves Thrombolytic Therapy in Focal Embolic Stroke.
Q90409417Glia-immune interactions post-ischemic stroke and potential therapies
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Q38793026Impact of Comorbidities on Acute Injury and Recovery in Preclinical Stroke Research: Focus on Hypertension and Diabetes
Q36976259Intracranial aneurysm formation in type-one diabetes rats
Q36614594Matrix Metalloprotease 3 Exacerbates Hemorrhagic Transformation and Worsens Functional Outcomes in Hyperglycemic Stroke
Q38776714Minocycline Promotes Neurite Outgrowth of PC12 Cells Exposed to Oxygen-Glucose Deprivation and Reoxygenation Through Regulation of MLCP/MLC Signaling Pathways
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Q35187936Systemic inflammation impairs tissue reperfusion through endothelin-dependent mechanisms in cerebral ischemia.
Q88670464Targeting Reperfusion Injury in the Age of Mechanical Thrombectomy
Q36267227Targeting neutrophils in ischemic stroke: translational insights from experimental studies.
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Q64951216tPA Helpers in the Treatment of Acute Ischemic Stroke: Are They Ready for Clinical Use?
Q37366918von Willebrand factor contributes to poor outcome in a mouse model of intracerebral haemorrhage

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