Hypoxia-induced neuroinflammatory white-matter injury reduced by minocycline in SHR/SP.

scientific article

Hypoxia-induced neuroinflammatory white-matter injury reduced by minocycline in SHR/SP. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/JCBFM.2015.21
P932PMC publication ID4640265
P698PubMed publication ID25712499
P5875ResearchGate publication ID272841226

P50authorTamara RoitbakQ86101237
P2093author name stringYi Yang
Gary A Rosenberg
Jeffrey F Thompson
Fakhreya Y Jalal
P2860cites workMinocycline attenuates white matter damage in a rat model of chronic cerebral hypoperfusionQ46873075
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Matrix metalloproteinase-2 plays a critical role in the pathogenesis of white matter lesions after chronic cerebral hypoperfusion in rodents.Q48410331
White matter lesions in an unselected cohort of the elderly: molecular pathology suggests origin from chronic hypoperfusion injuryQ48575517
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.Q48785632
Increased apparent diffusion coefficients on MRI linked with matrix metalloproteinases and edema in white matter after bilateral carotid artery occlusion in ratsQ48871135
Vascular Permeability Precedes Spontaneous Intracerebral Hemorrhage in Stroke-Prone Spontaneously Hypertensive RatsQ54999944
Analysis of pathological events at the onset of brain damage in stroke-prone rats: A proteomics and magnetic resonance imaging approachQ57398867
White matter damage is associated with matrix metalloproteinases in vascular dementiaQ73843398
A conserved family of prolyl-4-hydroxylases that modify HIFQ24291794
The pathobiology of vascular dementiaQ27006033
Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challengesQ28287345
The immunology of stroke: from mechanisms to translationQ29620066
New insights into brain damage in stroke-prone rats: a nuclear magnetic imaging studyQ30677191
Chronic cerebral hypoperfusion induces white matter lesions and loss of oligodendroglia with DNA fragmentation in the rat.Q31166365
Minocycline attenuates cognitive impairment and restrains oxidative stress in the hippocampus of rats with chronic cerebral hypoperfusionQ33374279
Tissue oxygen is reduced in white matter of spontaneously hypertensive-stroke prone rats: a longitudinal study with electron paramagnetic resonanceQ33581206
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke associationQ33967781
National Institute of Neurological Disorders and Stroke-Canadian Stroke Network vascular cognitive impairment harmonization standardsQ33998646
Myelin loss associated with neuroinflammation in hypertensive ratsQ34169644
Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangementQ34170971
Oligodendrocytes and ischemic brain injuryQ35079513
Magnetic resonance imaging quantification of regional cerebral blood flow and cerebrovascular reactivity to carbon dioxide in normotensive and hypertensive rats.Q35129811
Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicityQ35998064
Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?Q36079321
A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic windowQ36678875
Effects of minocycline plus tissue plasminogen activator combination therapy after focal embolic stroke in type 1 diabetic ratsQ36783536
Direct visualization of mouse brain oxygen distribution by electron paramagnetic resonance imaging: application to focal cerebral ischemia.Q36786734
An MRI-histological study of white matter in stroke-free SHRSPQ36839958
Increased prolyl 4-hydroxylase expression and differential regulation of hypoxia-inducible factors in the aged rat brainQ37264295
Matrix metalloproteinases and their multiple roles in neurodegenerative diseasesQ37375110
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiologyQ38128383
Induction of hypoxia-inducible factor-1 (HIF-1) and its target genes following focal ischaemia in rat brainQ41707011
Effects of intravenous dimethyl sulfoxide on ischemia evolution in a rat permanent occlusion modelQ41817314
Diazoxide and dimethyl sulphoxide alleviate experimental cerebral hypoperfusion-induced white matter injury in the rat brain.Q45201851
Post-insult minocycline treatment attenuates hypoxia-ischemia-induced neuroinflammation and white matter injury in the neonatal rat: a comparison of two different dose regimensQ46665142
P433issue7
P921main subjecthypoxiaQ105688
minocyclineQ415336
P304page(s)1145-1153
P577publication date2015-02-25
P1433published inJournal of Cerebral Blood Flow & MetabolismQ14663525
P1476titleHypoxia-induced neuroinflammatory white-matter injury reduced by minocycline in SHR/SP.
P478volume35

Reverse relations

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