Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome

scientific article published on March 2016

Impact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.11909/J.ISSN.1671-5411.2016.03.007
P932PMC publication ID4826890
P698PubMed publication ID27103915

P50authorZenon HuczekQ56936704
Claudio MorettiQ57292495
Fabrizio D'AscenzoQ61163714
P2093author name stringYan Yan
José R González-Juanatey
Xiao Wang
Stephen B Wilton
Xian-Tao Song
Emad Abu-Assi
Christoph Liebetrau
Dimitrios Alexopoulos
Masa-Aki Kawashiri
Shao-Ping Nie
Wouter J Kikkert
Jorge Saucedo
Sasko Kedev
Sergio Raposeiras-Roubín
Toshiharu Fujii
Tetsuma Kawaji
Jing-Yao Fan
Iván Nuñez-Gil
Albert Ariza-Sole
Jose P Simao Henriques
Luis C Correia
P2860cites workInfluence of omeprazol on the antiplatelet action of clopidogrel associated to aspirinQ28200091
Proton Pump Inhibitor Usage and the Risk of Myocardial Infarction in the General PopulationQ28548045
Impact of proton pump inhibitor therapy on the efficacy of clopidogrel in the CAPRIE and CREDO trialsQ30421742
Influence of omeprazole on the antiplatelet action of clopidogrel associated with aspirin: the randomized, double-blind OCLA (Omeprazole CLopidogrel Aspirin) studyQ34009506
2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment ElevatiQ34491521
Clopidogrel with or without omeprazole in coronary artery diseaseQ34660303
Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndromeQ34956075
Prognosis of concomitant users of clopidogrel and proton-pump inhibitors in a high-risk population for upper gastrointestinal bleedingQ35147463
Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trialsQ37590925
Cytochrome P450 2C19*2 polymorphism and cardiovascular recurrences in patients taking clopidogrel: a meta-analysisQ37721156
2011 ACCF/AHA/SCAI guideline for percutaneous coronary intervention: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Society for Cardiovascular Angiography and InterventiQ37953885
CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysisQ37971875
An insight into the interaction between clopidogrel and proton pump inhibitorsQ37980821
Ticagrelor: the first novel reversible P2Y(12) inhibitorQ38069896
Association of proton pump inhibitor use on cardiovascular outcomes with clopidogrel and ticagrelor: insights from the platelet inhibition and patient outcomes trialQ38477257
BleeMACS: rationale and design of the study.Q40941750
Proton pump inhibitor use represents an independent risk factor for myocardial infarctionQ41700008
Effects of the proton pump inhibitor lansoprazole on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrelQ42646492
Proton-pump inhibitors are associated with increased cardiovascular risk independent of clopidogrel use: a nationwide cohort studyQ42882409
Cardiovascular risk in clopidogrel-treated patients according to cytochrome P450 2C19*2 loss-of-function allele or proton pump inhibitor coadministration: a systematic meta-analysisQ42974062
Effects of pantoprazole and esomeprazole on platelet inhibition by clopidogrelQ46199177
Prasugrel versus clopidogrel in patients with acute coronary syndromesQ46915044
2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)Developed with the special contribuQ53460540
Clinical Events as a Function of Proton Pump Inhibitor Use, Clopidogrel Use, and Cytochrome P450 2C19 Genotype in a Large Nationwide Cohort of Acute Myocardial InfarctionQ57243377
Concomitant use of clopidogrel and proton pump inhibitors is not associated with major adverse cardiovascular events following coronary stent implantationQ57300220
2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: Executive SummaryQ59355889
Esomeprazole compared with famotidine in the prevention of upper gastrointestinal bleeding in patients with acute coronary syndrome or myocardial infarctionQ82636199
Clinical outcomes in patients with the concomitant use of clopidogrel and proton pump inhibitors after percutaneous coronary intervention: an analysis from the Guthrie Health Off-Label Stent (GHOST) investigatorsQ83565343
A randomized, 2-period, crossover design study to assess the effects of dexlansoprazole, lansoprazole, esomeprazole, and omeprazole on the steady-state pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteersQ83780327
Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison StudiesQ85036168
P433issue3
P921main subjectacute coronary syndromeQ266018
clopidogrelQ410237
P304page(s)209-217
P577publication date2016-03-01
P1433published inJournal of Geriatric CardiologyQ15765238
P1476titleImpact of concomitant use of proton pump inhibitors and clopidogrel or ticagrelor on clinical outcomes in patients with acute coronary syndrome
P478volume13

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Q91886489Antiplatelet treatment in acute coronary syndrome patients: Real-world data from the START-Antiplatelet Italian Registrycites workP2860

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