Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids

scientific article published on April 2007

Amino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1517/17425255.3.2.159
P698PubMed publication ID17428148

P2093author name stringJohn O Miners
Kathleen M Knights
Matthew J Sykes
P2860cites workReye syndrome--insights on causation and prognosisQ22299327
An immunoassay for a urinary metabolite as a biomarker of human exposure to the pyrethroid insecticide permethrinQ23916234
Developmental profile of mitochondrial glycine N-acyltransferase in human liverQ24313337
Purification to homogeneity of mitochondrial acyl coa:glycine n-acyltransferase from human liverQ24336243
Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/medium-chain fatty acid:CoA ligaseQ24533342
Alternative pathway therapy for urea cycle disorders: twenty years laterQ28142167
Reassessing Reye syndromeQ28166409
Triflusal: a review of its use in cerebral infarction and myocardial infarction, and as thromboprophylaxis in atrial fibrillationQ28196625
Screening newborns for multiple organic acidurias in dried filter paper urine samples: method developmentQ28333994
Mitochondrial metabolism of valproic acidQ28645778
Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acidsQ28646395
Pharmacokinetics of Salicylate Elimination in ManQ28646499
Isolation and sequencing of cDNAs for the XL-I and XL-III forms of bovine liver xenobiotic-metabolizing medium-chain fatty acid:CoA ligaseQ30812323
Isolation, sequencing, and expression of a cDNA for the HXM-A form of xenobiotic/medium-chain fatty acid:CoA ligase from human liver mitochondriaQ30891028
Synthesis and intramitochondrial levels of valproyl-coenzyme A metabolites.Q31951114
Reye's syndrome in the United States from 1981 through 1997.Q33860660
Interaction of salicylate and ibuprofen with the carboxylic acid: CoA ligases from bovine liver mitochondriaQ34404037
Isolation from bovine liver mitochondria and characterization of three distinct carboxylic acid: CoA ligases with activity toward xenobioticsQ34408502
Influence of gender and oral contraceptive steroids on the metabolism of salicylic acid and acetylsalicylic acidQ34447873
Xenobiotic acyl glucuronides and acyl CoA thioesters as protein-reactive metabolites with the potential to cause idiosyncratic drug reactionsQ34717194
Pharmacokinetics and pharmacodynamics of azosemideQ35547826
Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicityQ40379756
Mammalian mitochondrial beta-oxidationQ41280085
D,L-alpha-Fluoropalmitic acid inhibits sphingosine base formation and accumulates in membrane lipids of cultured mammalian cellsQ42255410
Metabolic effects of pivalate in isolated rat hepatocytesQ43509482
Glycine conjugation of para-aminobenzoic acid (PABA): a pilot study of a novel prognostic test in acute liver failure in childrenQ44260984
Absorption, distribution, metabolism and excretion of 4-chloro-2-methylphenoxyacetic acid (MCPA) in ratsQ44663555
In vitro reactivity of carboxylic acid-CoA thioesters with glutathioneQ44731636
Acyl-CoA synthetases in guinea-pig liver mitochondria. Purification and characterization of a distinct propionyl-CoA synthetaseQ45020422
Benzoate treatment and the glycine index in nonketotic hyperglycinaemiaQ46694228
In vitro and in vivo studies on acyl-coenzyme A-dependent bioactivation of zomepirac in ratsQ46813973
Long-term use of high-dose benzoate and dextromethorphan for the treatment of nonketotic hyperglycinemia.Q52188052
Hypoglycin, the famous toxin of the unripe Jamaican ackee fruitQ56679720
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)159-168
P577publication date2007-04-01
P1433published inExpert Opinion on Drug Metabolism & ToxicologyQ5421205
P1476titleAmino acid conjugation: contribution to the metabolism and toxicity of xenobiotic carboxylic acids
P478volume3

Reverse relations

cites work (P2860)
Q38206257A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids
Q50911347Absorption, metabolism and excretion of cobimetinib, an oral MEK inhibitor, in rats and dogs.
Q37155833Biosynthesis, degradation and pharmacological importance of the fatty acid amides
Q35063581Determinants of aspirin metabolism in healthy men and women: effects of dietary inducers of UDP-glucuronosyltransferases
Q37700321Expression, purification, and characterization of mouse glycine N-acyltransferase in Escherichia coli
Q38104736Glycine conjugation: importance in metabolism, the role of glycine N-acyltransferase, and factors that influence interindividual variation.
Q101574258Identification of critical genetic variants associated with metabolic phenotypes of the Japanese population
Q39162099In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid.
Q37937051Metabolic activation in drug-induced liver injury
Q48320225New insights into the catalytic mechanism of human glycine N-acyltransferase.
Q38929936Non-cytochrome P450-mediated bioactivation and its toxicological relevance.
Q36231628Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry-based metabolomics
Q42111515Reversible lysine acetylation regulates activity of human glycine N-acyltransferase-like 2 (hGLYATL2): implications for production of glycine-conjugated signaling molecules
Q28831354Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity
Q90294112Stable Isotope-Assisted Metabolomics for Deciphering Xenobiotic Metabolism in Mammalian Cell Culture
Q52664662The Use of p-Aminobenzoic Acid as a Probe Substance for the Targeted Profiling of Glycine Conjugation.
Q47717211The influence of physicochemical properties on the reactivity and stability of acyl glucuronides †.
Q48813784The metabolic fate of [14C]-fenclozic acid in the hepatic reductase null (HRN) mouse
Q40867989The simultaneous detection and quantification of p-aminobenzoic acid and its phase 2 biotransformation metabolites in human urine using LC-MS/MS.
Q38879491Xenobiotic/medium chain fatty acid: CoA ligase - a critical review on its role in fatty acid metabolism and the detoxification of benzoic acid and aspirin

Search more.