Cysteine mutants of herpes simplex virus type 1 glycoprotein D exhibit temperature-sensitive properties in structure and function.

scientific article published on November 1990

Cysteine mutants of herpes simplex virus type 1 glycoprotein D exhibit temperature-sensitive properties in structure and function. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.64.11.5542-5552.1990
P932PMC publication ID248606
P698PubMed publication ID2170686

P2093author name stringG H Cohen
R J Eisenberg
D Long
M I Muggeridge
P2860cites workNeutralizing monoclonal antibodies specific for herpes simplex virus glycoprotein D inhibit virus penetrationQ36919500
Infectivity and glycoprotein processing of herpes simplex virus type 1 grown in a ricin-resistant cell line deficient in N-acetylglucosaminyl transferase I.Q36924366
Glycopeptides of the Type-Common Glycoprotein gD of Herpes Simplex Virus Types 1 and 2Q36931969
Effect of monoclonal antibodies on limited proteolysis of native glycoprotein gD of herpes simplex virus type 1.Q36937956
Purification of glycoprotein gD of herpes simplex virus types 1 and 2 by use of monoclonal antibodyQ36939761
A single N-linked oligosaccharide at either of the two normal sites is sufficient for transport of vesicular stomatitis virus G protein to the cell surfaceQ36951369
Glycoprotein D protects mice against lethal challenge with herpes simplex virus types 1 and 2.Q37099580
Antigenic and functional analysis of a neutralization site of HSV-1 glycoprotein D.Q38342152
Neutralizing epitopes of lymphocytic choriomeningitis virus are conformational and require both glycosylation and disulfide bonds for expressionQ38344012
Vesicular stomatitis virus G proteins with altered glycosylation sites display temperature-sensitive intracellular transport and are subject to aberrant intermolecular disulfide bondingQ38347426
DNA sequence of the gene for pseudorabies virus gp50, a glycoprotein without N-linked glycosylationQ40127114
Specific intermediates in the folding reactions of small proteins and the mechanism of protein foldingQ40130917
Fibroblast growth factor receptor is a portal of cellular entry for herpes simplex virus type 1.Q41730825
Characterization of a disulphide bridge-stabilized antigenic domain of tick-borne encephalitis virus structural glycoproteinQ42988879
Structure-function relationships for the IL-2 receptor system. V. Structure-activity analysis of modified and truncated forms of the Tac receptor protein: site-specific mutagenesis of cysteine residues.Q45166110
PENETRATION OF HERPES SIMPLEX VIRUS INTO HUMAN EPIDERMOID CELLS.Q45714054
DNA sequence of the Herpes simplex virus type 2 glycoprotein D geneQ45796837
Anti-gD monoclonal antibodies inhibit cell fusion induced by herpes simplex virus type 1Q45797827
Herpes Simplex Virus Type-1 Glycoprotein D Gene: Nucleotide Sequence and Expression inEscherichia coliQ45799667
Herpes simplex virus glycoprotein D is sufficient to induce spontaneous pH-independent fusion in a cell line that constitutively expresses the glycoproteinQ45834230
Functional regions and structural features of the gB glycoprotein of herpes simplex virus type 1. An analysis of linker insertion mutantsQ45841035
An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralizationQ45848368
Stability of wild-type and mutant RTEM-1 beta-lactamases: effect of the disulfide bondQ46714320
Substantial increase of protein stability by multiple disulphide bondsQ59056666
Conformational changes associated with proteolytic processing of presecretory proteins allow glutathione-catalyzed formation of native disulfide bondsQ71439773
“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein AQ28131712
Conformational stability and activity of ribonuclease T1 with zero, one, and two intact disulfide bondsQ28308021
Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicryQ28646789
Supercoil sequencing: a fast and simple method for sequencing plasmid DNAQ29618184
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsinQ33669928
Comparative structural analysis of glycoprotein gD of herpes simplex virus types 1 and 2Q33923748
Construction and properties of a cell line constitutively expressing the herpes simplex virus glycoprotein B dependent on functional alpha 4 protein synthesisQ33928829
Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbitQ34162054
Anti-glycoprotein D antibodies that permit adsorption but block infection by herpes simplex virus 1 prevent virion-cell fusion at the cell surfaceQ34335593
Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4.Q36431330
Structural analysis of precursor and product forms of type-common envelope glycoprotein D (CP-1 antigen) of herpes simplex virus type 1Q36501558
Synthesis and processing of glycoproteins gD and gC of herpes simplex virus type 1.Q36507398
Type-Common CP-1 Antigen of Herpes Simplex Virus Is Associated with a 59,000-Molecular-Weight Envelope GlycoproteinQ36522265
Different roles of individual N-linked oligosaccharide chains in folding, assembly, and transport of the simian virus 5 hemagglutinin-neuraminidaseQ36708016
Identification of nonessential disulfide bonds and altered conformations in the v-sis protein, a homolog of the B chain of platelet-derived growth factorQ36784625
Functional contribution of cysteine residues to the human immunodeficiency virus type 1 envelopeQ36805937
Soluble forms of herpes simplex virus glycoprotein D bind to a limited number of cell surface receptors and inhibit virus entry into cellsQ36806734
Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virusQ36825917
Fine mapping of antigenic site II of herpes simplex virus glycoprotein DQ36827612
Glycoprotein cytoplasmic domain sequences required for rescue of a vesicular stomatitis virus glycoprotein mutantQ36830119
Influence of asparagine-linked oligosaccharides on antigenicity, processing, and cell surface expression of herpes simplex virus type 1 glycoprotein D.Q36832178
A herpes simplex virus mutant in which glycoprotein D sequences are replaced by beta-galactosidase sequences binds to but is unable to penetrate into cellsQ36866557
Expression of herpes simplex virus type 1 glycoprotein D deletion mutants in mammalian cellsQ36868575
The contribution of cysteine residues to antigenicity and extent of processing of herpes simplex virus type 1 glycoprotein DQ36868606
Antigenic analysis of a major neutralization site of herpes simplex virus glycoprotein D, using deletion mutants and monoclonal antibody-resistant mutantsQ36872389
Herpes simplex viruses lacking glycoprotein D are unable to inhibit virus penetration: quantitative evidence for virus-specific cell surface receptorsQ36873841
Localization of discontinuous epitopes of herpes simplex virus glycoprotein D: use of a nondenaturing ("native" gel) system of polyacrylamide gel electrophoresis coupled with Western blottingQ36883752
Specificities of monoclonal and polyclonal antibodies that inhibit adsorption of herpes simplex virus to cells and lack of inhibition by potent neutralizing antibodies.Q36903438
Synthesis and processing of glycoprotein D of herpes simplex virus types 1 and 2 in an in vitro systemQ36909711
Localization and synthesis of an antigenic determinant of herpes simplex virus glycoprotein D that stimulates the production of neutralizing antibodyQ36910738
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectHerpes simplex virus type 1Q655331
P1104number of pages11
P304page(s)5542-5552
P577publication date1990-11-01
P1433published inJournal of VirologyQ1251128
P1476titleCysteine mutants of herpes simplex virus type 1 glycoprotein D exhibit temperature-sensitive properties in structure and function
P478volume64

Reverse relations

cites work (P2860)
Q36797418Absence of asparagine-linked oligosaccharides from glycoprotein D of herpes simplex virus type 1 results in a structurally altered but biologically active protein
Q38320624Analysis of bovine herpesvirus 1 glycoprotein gIV truncations and deletions expressed by recombinant vaccinia viruses
Q40959831Analysis of the steps involved in Dengue virus entry into host cells
Q45783866Characterization of a Marek's disease virus mutant containing a lacZ insertion in the US6 (gD) homologue gene
Q36797424Characterization of a recombinant herpes simplex virus which expresses a glycoprotein D lacking asparagine-linked oligosaccharides
Q40275833Contribution of cysteine residues in the extracellular domain of the F protein of human respiratory syncytial virus to its function
Q35868099Cross-linking of glycoprotein oligomers during herpes simplex virus type 1 entry
Q27486188Disulfide bond structure of glycoprotein D of herpes simplex virus types 1 and 2
Q36685075Equine herpesvirus 1 glycoprotein D: mapping of the transcript and a neutralization epitope
Q33785686Examination of the kinetics of herpes simplex virus glycoprotein D binding to the herpesvirus entry mediator, using surface plasmon resonance
Q30416754Identification of functional regions of herpes simplex virus glycoprotein gD by using linker-insertion mutagenesis
Q33937712Manipulating disulfide bond formation and protein folding in the endoplasmic reticulum
Q35076854Mutagenesis of varicella-zoster virus glycoprotein I (gI) identifies a cysteine residue critical for gE/gI heterodimer formation, gI structure, and virulence in skin cells
Q33819172Mutation of neuraminidase cysteine residues yields temperature-sensitive influenza viruses
Q39594848Replication of murine cytomegalovirus in differentiated macrophages as a determinant of viral pathogenesis
Q40326023The cytoplasmic domain of the F protein of Human respiratory syncytial virus is not required for cell fusion
Q39580163The disulfide-bonded structure of feline herpesvirus glycoprotein I.
Q34355812Truncated forms of glycoprotein D of herpes simplex virus 1 capable of blocking apoptosis and of low-efficiency entry into cells form a heterodimer dependent on the presence of a cysteine located in the shared transmembrane domains

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