Contribution of cysteine residues in the extracellular domain of the F protein of human respiratory syncytial virus to its function

scientific article published on 24 May 2006

Contribution of cysteine residues in the extracellular domain of the F protein of human respiratory syncytial virus to its function is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1045197258
P356DOI10.1186/1743-422X-3-34
P932PMC publication ID1540417
P698PubMed publication ID16723026
P5875ResearchGate publication ID7059862

P2093author name stringAlfred M Del Vecchio
Changbao Liu
Lester L Gutshall
Nicole D Day
Patrick J Branigan
Robert T Sarisky
José A Melero
Jianquan Luo
P2860cites workUse of a novel cell-based fusion reporter assay to explore the host range of human respiratory syncytial virus F proteinQ24815873
Structural characterization of the human respiratory syncytial virus fusion protein coreQ27628799
The structure of the fusion glycoprotein of Newcastle disease virus suggests a novel paradigm for the molecular mechanism of membrane fusionQ27631011
The structural biology of type I viral membrane fusionQ28188215
Mortality associated with influenza and respiratory syncytial virus in the United StatesQ29615578
Viral infections in immunocompromised patients: what's new with respiratory viruses?Q30309653
Characterization of two antigenic sites recognized by neutralizing monoclonal antibodies directed against the fusion glycoprotein of human respiratory syncytial virusQ30334543
Isolation of a second recombinant human respiratory syncytial virus monoclonal antibody fragment (Fab RSVF2-5) that exhibits therapeutic efficacy in vivoQ32071192
Recombinant respiratory syncytial virus bearing a deletion of either the NS2 or SH gene is attenuated in chimpanzees.Q33645414
Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5' proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaQ33707803
Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutantQ33738521
Fatty acid acylation of the fusion glycoprotein of human respiratory syncytial virusQ45843467
Post-translational Processing and Oligomerization of the Fusion Glycoprotein of Human Respiratory Syncytial VirusQ45857342
Protective epitopes on the fusion protein of respiratory syncytial virus recognized by murine and bovine monoclonal antibodiesQ45872477
Intracellular processing of the human respiratory syncytial virus fusion glycoprotein: amino acid substitutions affecting folding, transport and cleavageQ45873290
Identification of the respiratory syncytial virus proteins required for formation and passage of helper-dependent infectious particles.Q33785124
Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion proteinQ33855371
Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusionQ33934074
Respiratory syncytial virus infections in immunocompromised adultsQ34004104
Analysis of the genomic sequence of a human metapneumovirusQ34130526
Inhibition of Respiratory Syncytial Virus Fusion by the Small Molecule VP-14637 via Specific Interactions with F ProteinQ34975477
Disulfide bonds as switches for protein functionQ35114294
Orally active fusion inhibitor of respiratory syncytial virusQ35547902
Respiratory syncytial virus fusion glycoprotein: nucleotide sequence of mRNA, identification of cleavage activation site and amino acid sequence of N-terminus of F1 subunitQ36137180
Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouseQ36548529
Marked differences in the antigenic structure of human respiratory syncytial virus F and G glycoproteinsQ36780922
Cysteine mutants of herpes simplex virus type 1 glycoprotein D exhibit temperature-sensitive properties in structure and function.Q36793428
Conformational studies of a short linear peptide corresponding to a major conserved neutralizing epitope of human respiratory syncytial virus fusion glycoproteinQ36823304
Temperature-sensitive Mutants of Respiratory Syncytial VirusQ37133871
RFI-641 inhibits entry of respiratory syncytial virus via interactions with fusion proteinQ39416825
The core of the respiratory syncytial virus fusion protein is a trimeric coiled coilQ39591661
N-glycans of F protein differentially affect fusion activity of human respiratory syncytial virusQ39602758
Functional analysis of recombinant respiratory syncytial virus deletion mutants lacking the small hydrophobic and/or attachment glycoprotein geneQ39603697
Assignment of disulfide bridges in the fusion glycoprotein of Sendai virus.Q40040650
Two disulfide-linked polypeptide chains constitute the active F protein of paramyxovirusesQ40081618
Monoclonal antibodies to respiratory syncytial virus proteins: identification of the fusion proteinQ40137560
The cytoplasmic domain of the F protein of Human respiratory syncytial virus is not required for cell fusionQ40326023
Protein-disulfide isomerase-mediated reduction of two disulfide bonds of HIV envelope glycoprotein 120 occurs post-CXCR4 binding and is required for fusionQ40705636
Respiratory syncytial virus with the fusion protein as its only viral glycoprotein is less dependent on cellular glycosaminoglycans for attachment than complete virusQ40732224
Contribution of the respiratory syncytial virus G glycoprotein and its secreted and membrane-bound forms to virus replication in vitro and in vivoQ40771213
Furin cleavage of the respiratory syncytial virus fusion protein is not a requirement for its transport to the surface of virus-infected cellsQ40803835
Cleavage of the respiratory syncytial virus fusion protein is required for its surface expression: role of furinQ40863649
Recombinant respiratory syncytial viruses with deletions in the NS1, NS2, SH, and M2-2 genes are attenuated in vitro and in vivoQ40868890
Mechanism of selective inhibition of respiratory syncytial virus by a benzodithiin compound (RD3-0028).Q43724047
Multiple glycosylated forms of the respiratory syncytial virus fusion protein are expressed in virus-infected cellsQ43830376
Modelling the structure of the fusion protein from human respiratory syncytial virusQ44009340
Substituted benzimidazoles with nanomolar activity against respiratory syncytial virusQ44668921
Thermostability of the human respiratory syncytial virus fusion protein before and after activation: implications for the membrane-fusion mechanismQ45548739
Structural characterization of respiratory syncytial virus fusion inhibitor escape mutants: homology model of the F protein and a syncytium formation assayQ45722724
Cloning, expression, and crystallization of the fusion protein of Newcastle disease virusQ45733423
Heptad-repeat regions of respiratory syncytial virus F1 protein form a six-membered coiled-coil complexQ45740595
Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodiesQ45742418
A direct comparison of the activities of two humanized respiratory syncytial virus monoclonal antibodies: MEDI-493 and RSHZl9.Q45749179
Respiratory syncytial virus pneumonia among the elderly: an assessment of disease burdenQ45752482
Development of a humanized monoclonal antibody (MEDI-493) with potent in vitro and in vivo activity against respiratory syncytial virusQ45759631
Analysis of respiratory syncytial virus F, G, and SH proteins in cell fusionQ45778546
Isolation and characterization of a highly attenuated respiratory syncytial virus (RSV) vaccine candidate by mutagenesis of the incompletely attenuated RSV A2 ts-1 NG-1 mutant virusQ45789084
Respiratory syncytial virus polypeptides. III. The envelope-associated proteinsQ45794076
Characterization of the 10 proteins of human respiratory syncytial virus: identification of a fourth envelope-associated proteinQ45828134
Nucleotide sequence of the gene encoding the Newcastle disease virus fusion protein and comparisons of paramyxovirus fusion protein sequencesQ45829414
P921main subjectrespiratory syncytial virusQ1052913
RSV precursor fusion glycoprotein F0Q115694203
P304page(s)34
P577publication date2006-05-24
P1433published inVirology JournalQ7934868
P1476titleContribution of cysteine residues in the extracellular domain of the F protein of human respiratory syncytial virus to its function
P478volume3

Reverse relations

cites work (P2860)
Q36149102A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.
Q36851832A conserved region between the heptad repeats of paramyxovirus fusion proteins is critical for proper F protein folding
Q37332290A single amino acid in the F2 subunit of respiratory syncytial virus fusion protein alters growth and fusogenicity
Q39915575Characterization of a persistent respiratory syncytial virus showing a low-fusogenic activity associated to an impaired F protein.
Q34191108Characterization of neutralizing affinity-matured human respiratory syncytial virus F binding antibodies in the sub-picomolar affinity range
Q35689697Cholesterol-rich microdomains as docking platforms for respiratory syncytial virus in normal human bronchial epithelial cells
Q42251545Detection of respiratory syncytial virus fusion protein variants between 2009 and 2012 in China
Q38267482Gene sequence variability of the three surface proteins of human respiratory syncytial virus (HRSV) in Texas
Q90681995Impact of Respiratory Syncytial Virus Infection on the Host Cell: Implications for Antiviral Strategies
Q39154023Modulation of the host immune response by respiratory syncytial virus proteins
Q40059727Neutralizing epitopes of RSV and palivizumab resistance in Japan
Q41816990Relationship between the loss of neutralizing antibody binding and fusion activity of the F protein of human respiratory syncytial virus
Q91361642Respiratory syncytial virus entry and how to block it
Q35076596Soluble respiratory syncytial virus fusion protein in the fully cleaved, pretriggered state is triggered by exposure to low-molarity buffer
Q34414405Structure and function of respiratory syncytial virus surface glycoproteins.
Q27668015Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes
Q55442083Viral Entry Properties Required for Fitness in Humans Are Lost through Rapid Genomic Change during Viral Isolation.