Mechanisms of disease: L-arginine in coronary atherosclerosis--a clinical perspective

scientific article published on May 2007

Mechanisms of disease: L-arginine in coronary atherosclerosis--a clinical perspective is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1038/NCPCARDIO0878
P698PubMed publication ID17457351

P50authorDimitris TousoulisQ90167660
Elli StefanadiQ117271853
Christodoulos I. StefanadisQ17308889
Gerasimos SiasosQ54165911
P2093author name stringCharalambos Antoniades
Rainer H Böger
P2860cites workEffect of increased availability of endothelium-derived nitric oxide precursor on endothelium-dependent vascular relaxation in normal subjects and in patients with essential hypertension.Q54240963
L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits.Q54310603
Effects of in vivo and in vitro L-arginine supplementation on healthy human vessels.Q55066644
Dietary l-arginine and α-tocopherol reduce vascular oxidative stress and preserve endothelial function in hypercholesterolemic rabbits via different mechanismsQ60723135
Dietary l -Arginine Reduces the Progression of Atherosclerosis in Cholesterol-Fed RabbitsQ60723154
Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO productionQ60723170
Effects of L-arginine supplementation on endothelium-dependent coronary vasodilation in patients with angina pectoris and normal coronary arteriogramsQ71170633
Effect of L-arginine on acetylcholine-induced endothelium-dependent vasodilation differs between the coronary and forearm vasculatures in humansQ72726505
Local L-arginine delivery after balloon angioplasty reduces monocyte binding and induces apoptosisQ73114809
A novel nonenzymatic pathway for the generation of nitric oxide by the reaction of hydrogen peroxide and D- or L-arginineQ73325920
Serum cholesterol level, cigarette smoking, and vasomotor responses to L-arginine in narrowed epicardial coronary arteriesQ73574912
Oral L-arginine in patients with coronary artery disease on medical managementQ73762604
Arginine intake and risk of coronary heart disease mortality in elderly menQ74290899
Continuous perivascular L-arginine delivery increases total vessel area and reduces neointimal thickening after experimental balloon dilatationQ74598510
Role of nitric oxide in restenosis after experimental balloon angioplasty in the hypercholesterolemic rabbit: effects on neointimal hyperplasia and vascular remodelingQ74611649
Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humansQ74645901
Clinical and inflammatory effects of dietary L-arginine in patients with intractable angina pectorisQ77769400
Combination therapy of cholesterol reduction and L-arginine supplementation controls accelerated vein graft atheromaQ78192250
Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variantQ24294275
Oral L-arginine improves endothelial function in healthy individuals older than 70 yearsQ28205825
Effect of supplemental oral L-arginine on exercise capacity in patients with stable angina pectorisQ28246683
Endothelial nitric oxide synthase in vascular disease: from marvel to menaceQ28305279
The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginineQ33882001
Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradoxQ34961072
L-arginine in cardiovascular disease: dream or reality?Q35055189
Effects of vitamin C on intracoronary L-arginine dependent coronary vasodilatation in patients with stable anginaQ35584813
Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathwayQ35754540
Antiatherogenic effects of L-arginine in the hypercholesterolemic rabbitQ35822869
Asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, explains the "L-arginine paradox" and acts as a novel cardiovascular risk factorQ35909742
Asymmetric dimethylarginine (ADMA): a novel risk marker in cardiovascular medicine and beyondQ36438224
Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults.Q37354435
Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: results from the AtheroGene StudyQ40397164
Effects of L-arginine on atherogenesis and endothelial dysfunction due to secondhand smokeQ41679296
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationshipQ42126268
Effect of local delivery of L-arginine on in-stent restenosis in humansQ42164909
Randomized trial of a medical food for the dietary management of chronic, stable anginaQ43477405
Endothelium-dependent vasodilation is independent of the plasma L-arginine/ADMA ratio in men with stable angina: lack of effect of oral L-arginine on endothelial function, oxidative stress and exercise performanceQ43703668
Oral L-arginine (and other active ingredients) for ischemic heart disease?.Q43832644
Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study.Q43850038
L-arginine infusion decreases plasma total homocysteine concentrations through increased nitric oxide production and decreased oxidative status in Type II diabetic patientsQ44110184
ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitaminsQ44264415
Adverse effects of supplemental L-arginine in atherosclerosis: consequences of methylation stress in a complex catabolism?Q44275915
Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood VesselsQ44601105
Regulation of the expression of inducible nitric oxide synthaseQ45089049
Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits.Q46037040
Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbitQ46086523
L-arginine improves endothelial function and reduces LDL oxidation in patients with stable coronary artery diseaseQ46685343
L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trialQ46878007
Oral L-arginine improves endothelium-dependent dilatation and reduces monocyte adhesion to endothelial cells in young men with coronary artery disease.Q51576241
Enhanced monocyte tissue factor response after experimental balloon angioplasty in hypercholesterolemic rabbit: inhibition with dietary L-arginine.Q53758176
Does acute improvement of endothelial dysfunction in coronary artery disease improve myocardial ischemia? A double-blind comparison of parenteral D- and L-arginine.Q54121894
P433issue5
P921main subjectatherosclerosisQ12252367
P304page(s)274-283
P577publication date2007-05-01
P1433published inNature Clinical Practice Cardiovascular MedicineQ15727036
P1476titleMechanisms of disease: L-arginine in coronary atherosclerosis--a clinical perspective
P478volume4

Reverse relations

cites work (P2860)
Q60930929Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction
Q37370572Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk
Q43148243Early prevention by L-Arginine attenuates coronary atherosclerosis in a model of hypercholesterolemic animals; no positive results for treatment
Q37435334Impaired Endothelial Nitric Oxide Synthase Homodimer Formation Triggers Development of Transplant Vasculopathy - Insights from a Murine Aortic Transplantation Model.
Q55353903LDL-cholesterol lowering effect of a new dietary supplement: an open label, controlled, randomized, cross-over clinical trial in patients with mild-to-moderate hypercholesterolemia.
Q38570304LXRα regulates macrophage arginase 1 through PU.1 and interferon regulatory factor 8.
Q37951442Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis
Q95642577NMR-based plasma metabolic profiling in patients with unstable angina
Q37887771Nitric oxide: a guardian for vascular grafts?
Q30916861Oral L-arginine supplementation in acute myocardial infarction therapy: a meta-analysis of randomized controlled trials
Q42585427Oral administration of L-arginine in patients with angina or following myocardial infarction may be protective by increasing plasma superoxide dismutase and total thiols with reduction in serum cholesterol and xanthine oxidase
Q34679092Oxidized low-density lipoprotein inhibits nitric oxide-mediated coronary arteriolar dilation by up-regulating endothelial arginase I
Q83131273Probing of L-arginine as an additive for the temperature-induced aggregation of veterinary growth hormones: fluorescence study
Q37662195The endothelial cell in health and disease: its function, dysfunction, measurement and therapy
Q46081694The impact of oral L-arginine supplementation on acute smoking-induced endothelial injury and arterial performance.
Q41808077The prevention of endothelial dysfunction through endothelial cell apoptosis inhibition in a hypercholesterolemic rabbit model: the effect of L-arginine supplementation
Q40733394Unveiling differences between patients with acute coronary syndrome with and without ST elevation through fingerprinting with CE-MS and HILIC-MS targeted analysis
Q36464510Variation in L-arginine intake follow demographics and lifestyle factors that may impact cardiovascular disease risk
Q37102697Vasomotor regulation of coronary microcirculation by oxidative stress: role of arginase

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