| scholarly article | Q13442814 |
| P50 | author | Kutralanathan Renganathan | Q55272367 |
| Robert G. Salomon | Q55807340 | ||
| Malgorzata Rozanowska | Q60728674 | ||
| P2093 | author name string | Vera L Bonilha | |
| Michael E Boulton | |||
| John W Crabb | |||
| Joe G Hollyfield | |||
| John S Crabb | |||
| Janet R Sparrow | |||
| Xiaorong Gu | |||
| So Ra Kim | |||
| Mary E Rayborn | |||
| Matthew W Davies | |||
| Bogdan Gugiu | |||
| Kwok-Peng Ng | |||
| P2860 | cites work | Lipofuscin is a photoinducible free radical generator. | Q50780961 |
| Ocular Age Pigment “A2-E”: An Unprecedented Pyridinium Bisretinoid | Q57903209 | ||
| Retinal age pigments generated by self-assembling lysosomotropic detergents | Q59071585 | ||
| Lipids in human lipofuscin-enriched subcellular fractions of two age populations. Comparison with rod outer segments and neural retina | Q68890101 | ||
| Levuglandin E2 crosslinks proteins | Q69685615 | ||
| Isolevuglandin-protein adducts in humans: products of free radical-induced lipid oxidation through the isoprostane pathway | Q73835683 | ||
| Photodamage to human RPE cells by A2-E, a retinoid component of lipofuscin | Q73991053 | ||
| Protein adducts of iso[4]levuglandin E2, a product of the isoprostane pathway, in oxidized low density lipoprotein | Q77985296 | ||
| The photoreactivity of the retinal age pigment lipofuscin | Q78122228 | ||
| The phagosome proteome: insight into phagosome functions | Q24674883 | ||
| Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium | Q28610021 | ||
| Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases | Q29012269 | ||
| Hydroxynonenal inactivates cathepsin B by forming Michael adducts with active site residues. | Q30330009 | ||
| Proteome analysis of lipofuscin in human retinal pigment epithelial cells | Q33184588 | ||
| Examining the proteins of functional retinal lipofuscin using proteomic analysis as a guide for understanding its origin | Q33230359 | ||
| Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration | Q33255664 | ||
| Nitric oxide and peroxynitrite. The ugly, the uglier and the not so good: a personal view of recent controversies | Q33814387 | ||
| Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy. | Q33932912 | ||
| Lipofuscin: mechanisms of age-related accumulation and influence on cell function | Q34147322 | ||
| Drusen proteome analysis: an approach to the etiology of age-related macular degeneration. | Q34378842 | ||
| Spectroscopic and morphological studies of human retinal lipofuscin granules | Q34867475 | ||
| Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration | Q34960196 | ||
| Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium | Q35133725 | ||
| The photoreactivity of ocular lipofuscin | Q35856412 | ||
| The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells | Q35865044 | ||
| RPE lipofuscin and its role in retinal pathobiology | Q36111032 | ||
| The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model. | Q36288534 | ||
| Proteomic and phototoxic characterization of melanolipofuscin: correlation to disease and model for its origin | Q37097697 | ||
| Oxidative damage-induced inflammation initiates age-related macular degeneration. | Q37357471 | ||
| Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium | Q40572299 | ||
| Proteomic analysis of human lysosomes: application to monocytic and breast cancer cells | Q40707530 | ||
| Formation of DNA-protein cross-links in mammalian cells by levuglandin E2. | Q41559219 | ||
| Small molecule RPE65 antagonists limit the visual cycle and prevent lipofuscin formation | Q42164095 | ||
| Photocytotoxicity of lipofuscin in human retinal pigment epithelial cells | Q42506829 | ||
| Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2. | Q43592238 | ||
| Effect of Rpe65 knockout on accumulation of lipofuscin fluorophores in the retinal pigment epithelium. | Q43785505 | ||
| Proteomic analysis of mature melanosomes from the retinal pigmented epithelium | Q44457989 | ||
| Carboxyethylpyrrole protein adducts and autoantibodies, biomarkers for age-related macular degeneration. | Q44552145 | ||
| Peroxidation of subcellular organelles: formation of lipofuscinlike fluorescent pigments | Q46348236 | ||
| Blue light induces mitochondrial DNA damage and free radical production in epithelial cells | Q46410687 | ||
| Levuglandin E2 inhibits mitosis and microtubule assembly | Q48963283 | ||
| The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. | Q50511473 | ||
| Blue light-induced reactivity of retinal age pigment. In vitro generation of oxygen-reactive species. | Q50759187 | ||
| Photophysical studies on human retinal lipofuscin. | Q50761874 | ||
| P433 | issue | 7 | |
| P304 | page(s) | 1397-1405 | |
| P577 | publication date | 2008-04-24 | |
| P1433 | published in | Molecular & Cellular Proteomics | Q6895932 |
| P1476 | title | Retinal pigment epithelium lipofuscin proteomics | |
| P478 | volume | 7 |
| Q35725801 | A chimeric Cfh transgene leads to increased retinal oxidative stress, inflammation, and accumulation of activated subretinal microglia in mice |
| Q41555677 | A2E and lipofuscin distributions in macaque retinal pigment epithelium are similar to human |
| Q33567644 | Abundant lipid and protein components of drusen |
| Q38221023 | Age-related macular degeneration and changes in the extracellular matrix |
| Q41856043 | Age-related macular degeneration in the aspect of chronic low-grade inflammation (pathophysiological parainflammation). |
| Q64077492 | An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease |
| Q99548948 | An In-Vitro Cell Model of Intracellular Protein Aggregation Provides Insights into RPE Stress Associated with Retinopathy |
| Q37212408 | Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers. |
| Q37152889 | BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration |
| Q37701967 | Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium. |
| Q36995212 | Carboxyethylpyrrole plasma biomarkers in age-related macular degeneration |
| Q28295779 | Chemistry of the retinoid (visual) cycle |
| Q89446142 | Compromised phagosome maturation underlies RPE pathology in cell culture and whole animal models of Smith-Lemli-Opitz Syndrome |
| Q36818305 | Cytotoxicity of all-trans-retinal increases upon photodegradation |
| Q35016735 | Distinct types of lipofuscin pigment in the hippocampus and cerebellum of aged cheirogaleid primates |
| Q38786743 | Drusen maculopathy: a risk factor for visual deterioration |
| Q34997806 | Experimental approaches to the study of A2E, a bisretinoid lipofuscin chromophore of retinal pigment epithelium |
| Q33801874 | Formation of lipofuscin-like material in the RPE Cell by different components of rod outer segments. |
| Q35174717 | Fundus Autofluorescence and RPE Lipofuscin in Age-Related Macular Degeneration |
| Q46069976 | Fundus autofluorescence and fate of glycoxidized particles injected into subretinal space in rabbit age-related macular degeneration model |
| Q92590621 | Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material |
| Q33728344 | Influence of ranibizumab treatment on the extracellular matrix in patients with neovascular age-related macular degeneration. |
| Q34135516 | Interpretations of fundus autofluorescence from studies of the bisretinoids of the retina |
| Q34057421 | Iron, the retina and the lens: a focused review |
| Q34814102 | Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium |
| Q54727999 | Light-induced damage to the retina: current understanding of the mechanisms and unresolved questions: a symposium-in-print. |
| Q36839855 | Lipofuscin and A2E accumulate with age in the retinal pigment epithelium of Nrl-/- mice |
| Q36052545 | Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal |
| Q50151446 | Lipofuscin-mediated photic stress inhibits phagocytic activity of ARPE-19 cells; effect of donors' age and antioxidants. |
| Q39137710 | Lipofuscins prepared by modification of photoreceptor cells via glycation or lipid peroxidation show the similar phototoxicity |
| Q34452853 | Mass spectrometry provides accurate and sensitive quantitation of A2E |
| Q38178092 | Metallothioneins (MTs) in the human eye: a perspective article on the zinc-MT redox cycle. |
| Q64084759 | Myocardial lipofuscin accumulation in ageing and sudden cardiac death |
| Q37101460 | New insights into retinoid metabolism and cycling within the retina |
| Q89480128 | Novel bisretinoids of human retina are lyso alkyl ether glycerophosphoethanolamine-bearing A2PE species |
| Q37801465 | Oxidation and age-related macular degeneration: insights from molecular biology |
| Q33577803 | Phospholipid meets all-trans-retinal: the making of RPE bisretinoids |
| Q38551646 | Photo-damage, photo-protection and age-related macular degeneration. |
| Q34994172 | Phototoxic action spectrum on a retinal pigment epithelium model of age-related macular degeneration exposed to sunlight normalized conditions |
| Q37294413 | Plasma protein pentosidine and carboxymethyllysine, biomarkers for age-related macular degeneration |
| Q26800956 | Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases |
| Q33562386 | Preliminary quantitative proteomic characterization of glaucomatous rat retinal ganglion cells. |
| Q38812131 | Prohibitin as the Molecular Binding Switch in the Retinal Pigment Epithelium. |
| Q35879035 | Proteomic Profiling in the Brain of CLN1 Disease Model Reveals Affected Functional Modules. |
| Q55646884 | Proteomics of Human Retinal Pigment Epithelium (RPE) Cells. |
| Q64914906 | Quantifying Retinal Pigment Epithelium Dysmorphia and Loss of Histologic Autofluorescence in Age-Related Macular Degeneration. |
| Q34010917 | Quantitative autofluorescence and cell density maps of the human retinal pigment epithelium. |
| Q33882986 | Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes |
| Q24604063 | Recent studies provide an updated clinical perspective on blue light-filtering IOLs |
| Q47169332 | Redox Active Transition Metal ions Make Melanin Susceptible to Chemical Degradation Induced by Organic Peroxide |
| Q26765278 | Relationship between Oxidative Stress, Circadian Rhythms, and AMD |
| Q51110368 | Retinal Histopathology in Eyes from a Patient with Stargardt disease caused by Compound Heterozygous ABCA4 Mutations. |
| Q38009850 | Retinal photodamage by endogenous and xenobiotic agents |
| Q36179752 | Retinal photodamage mediated by all-trans-retinal |
| Q37055774 | Retinal pigment epithelium (RPE) exosomes contain signaling phosphoproteins affected by oxidative stress |
| Q34967125 | Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium. |
| Q30883767 | Simultaneous decomposition of multiple hyperspectral data sets: signal recovery of unknown fluorophores in the retinal pigment epithelium |
| Q36921058 | Spatial and Spectral Characterization of Human Retinal Pigment Epithelium Fluorophore Families by Ex Vivo Hyperspectral Autofluorescence Imaging |
| Q33831456 | Spatial localization of A2E in the retinal pigment epithelium |
| Q88768149 | Spectral analysis of fundus autofluorescence pattern as a tool to detect early stages of degeneration in the retina and retinal pigment epithelium |
| Q41974923 | Stanniocalcin-1 rescued photoreceptor degeneration in two rat models of inherited retinal degeneration |
| Q33711681 | Structured illumination microscopy of autofluorescent aggregations in human tissue |
| Q37172298 | Structures and biogenetic analysis of lipofuscin bis-retinoids |
| Q38242789 | Studying melanin and lipofuscin in RPE cell culture models |
| Q37689580 | The Human Eye Proteome Project: perspectives on an emerging proteome |
| Q33998365 | The Retinal Pigment Epithelium in Health and Disease |
| Q35785390 | The bisretinoids of retinal pigment epithelium |
| Q26997523 | The proteomics of drusen |
| Q92360633 | The role of hypoxia-inducible factors in neovascular age-related macular degeneration: a gene therapy perspective |
| Q35624040 | The susceptibility of the retina to photochemical damage from visible light |
| Q52593970 | The ultrastructure, spatial distribution, and osmium tetroxide binding of lipofuscin and melanosomes in aging monkey retinal epithelium. |
| Q33598084 | The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometry |
| Q51579843 | Time-of-flight secondary ion mass spectrometry to assess spatial distribution of A2E and its oxidized forms within lipofuscin granules isolated from human retinal pigment epithelium. |
| Q41063126 | Towards Treatment of Stargardt Disease: Workshop Organized and Sponsored by the Foundation Fighting Blindness |
| Q40411841 | VISUALIZING RETINAL PIGMENT EPITHELIUM PHENOTYPES IN THE TRANSITION TO GEOGRAPHIC ATROPHY IN AGE-RELATED MACULAR DEGENERATION. |
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