Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear.

scientific article published on 10 September 2014

Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2014.08.029
P932PMC publication ID4837453
P698PubMed publication ID25218921
P5875ResearchGate publication ID265609438

P50authorChonnettia JonesQ37645584
David SprinzakQ42861078
Karen AvrahamQ56704862
P2093author name stringPing Chen
Shuangding Li
Dongdong Ren
Fanglu Chi
Sun Myoung Kim
Fumio Matsuzaki
Dong Qian
Lindsey Knapp
P2860cites workEngrailed: a gene controlling compartment and segment formation in DrosophilaQ24634741
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signalingQ24673748
Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouseQ28184694
Conserved patterns of cell movements during vertebrate gastrulationQ28242239
Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled bindingQ28254777
Wnt5a functions in planar cell polarity regulation in miceQ28505898
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebratesQ28506652
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathwayQ28509023
Ciliary proteins link basal body polarization to planar cell polarity regulationQ28585995
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulationQ28587130
Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activityQ28587927
Asymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner earQ28587932
Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammalsQ28591957
Identification of Vangl2 and Scrb1 as planar polarity genes in mammalsQ28593071
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cellsQ28593180
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathwaysQ29614619
The frizzled/stan pathway and planar cell polarity in the Drosophila wingQ30422383
Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanismsQ30425548
Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in miceQ31136145
Shaping the mammalian auditory sensory organ by the planar cell polarity pathwayQ34154050
Transposition of cloned P elements into Drosophila germ line chromosomes.Q34253758
A quest for the mechanism regulating global planar cell polarity of tissuesQ34989405
Diversin regulates heart formation and gastrulation movements in developmentQ35127535
Polarized translocation of fluorescent proteins in Xenopus ectoderm in response to Wnt signalingQ35392279
Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-cateninQ35741919
Van Gogh-like2 (Strabismus) and its role in planar cell polarity and convergent extension in vertebratesQ35913686
Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2Q37130918
Line up and listen: Planar cell polarity regulation in the mammalian inner ear.Q37512664
Pointing in the right direction: new developments in the field of planar cell polarity.Q37866626
Principles of planar polarity in animal developmentQ37869265
Asymmetric protein localization in planar cell polarity: mechanisms, puzzles, and challenges.Q38058902
Revisiting planar cell polarity in the inner ear.Q38096733
The mechanisms of planar cell polarity, growth and the Hippo pathway: some known unknownsQ38099601
Regulation of PCP by the Fat signaling pathwayQ38154247
Regulation of basal body and ciliary functions by DiversinQ39344703
Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.Q39791629
Centrosomal localization of Diversin and its relevance to Wnt signalingQ42579266
Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tailQ42653433
The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye.Q46883471
The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarizationQ47070692
Neuronal differentiation in Drosophila ommatidiumQ47889060
Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes.Q52088144
The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia.Q52107835
A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells.Q53086214
P433issue1
P407language of work or nameEnglishQ1860
P1104number of pages11
P304page(s)62-72
P577publication date2014-09-10
P1433published inDevelopmental BiologyQ3025402
P1476titleAnkrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear.
P478volume395

Reverse relations

cites work (P2860)
Q30278866Developmental regulation of planar cell polarity and hair-bundle morphogenesis in auditory hair cells: lessons from human and mouse genetics
Q99611754Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2
Q93133653PCP and Wnt pathway components act in parallel during zebrafish mechanosensory hair cell orientation
Q35978034Retracing the path of planar cell polarity.
Q38928250Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea
Q42362995The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation
Q33554612Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells.
Q92147741USP9X Deubiquitylates DVL2 to Regulate WNT Pathway Specification