Bone morphogenic proteins: applications in spinal surgery

scientific article published on September 2005

Bone morphogenic proteins: applications in spinal surgery is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11420-005-0120-4
P932PMC publication ID2504139
P698PubMed publication ID18751819
P5875ResearchGate publication ID23218464

P2093author name stringGerard K Jeong
Harvinder S Sandhu
James Farmer
P2860cites workOP-1 cDNA encodes an osteogenic protein in the TGF-beta familyQ24338365
Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiationQ24616097
Bone: formation by autoinductionQ28251545
Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamilyQ28292733
A 2-year follow-up pilot study evaluating the safety and efficacy of op-1 putty (rhbmp-7) as an adjunct to iliac crest autograft in posterolateral lumbar fusionsQ30423943
Posterolateral intertransverse process spinal arthrodesis with rhBMP-2 in a nonhuman primate: important lessons learned regarding dose, carrier, and safetyQ77924929
Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral discQ78051359
Anterior lumbar interbody fusion using rhBMP-2 with tapered interbody cagesQ78412809
Effect of bone morphogenetic protein-2 (BMP-2) on matrix production, other BMPs, and BMP receptors in rat intervertebral disc cellsQ80601733
A pilot safety and efficacy study of OP-1 putty (rhBMP-7) as an adjunct to iliac crest autograft in posterolateral lumbar fusionsQ30423956
Bone graft and bone graft substitutes: a review of current technology and applicationsQ33563643
Bioactive factors for bone tissue engineeringQ33765003
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Morbidity at bone graft donor sitesQ34549541
Bone-grafting and bone-graft substitutes.Q34557248
Pseudarthrosis of the spineQ35372073
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The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2Q41718333
Posterolateral lumbar intertransverse process spine arthrodesis with recombinant human bone morphogenetic protein 2/hydroxyapatite-tricalcium phosphate after laminectomy in the nonhuman primateQ42604254
Evaluation of rhBMP-2 with an OPLA carrier in a canine posterolateral (transverse process) spinal fusion modelQ42635764
Osteogenic protein-1 overcomes the inhibitory effect of nicotine on posterolateral lumbar fusionQ43688848
The effect of bone morphogenetic protein-2 on rat intervertebral disc cells in vitroQ44552343
Quantitative analysis of gene expression in a rabbit model of intervertebral disc degeneration by real-time polymerase chain reactionQ45226134
Histologic evaluation of the efficacy of rhBMP-2 compared with autograft bone in sheep spinal anterior interbody fusionQ46169377
Osteogenic protein-1 increases gene expression of vascular endothelial growth factor in primary cultures of fetal rat calvaria cellsQ46290804
Intertransverse process lumbar arthrodesis with allogeneic fresh-frozen bone graftQ46723864
Osseointegration of autograft versus osteogenic protein-1 in posterolateral spinal arthrodesis: emphasis on the comparative mechanisms of bone inductionQ47412645
A Cost Analysis of Bone Morphogenetic Protein Versus Autogenous Iliac Crest Bone Graft in Single-Level Anterior Lumbar FusionQ47425058
Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial: 2002 Volvo Award in clinical studiesQ48360114
2000 Young Investigator Research Award winner. Evaluation of OP-1 as a graft substitute for intertransverse process lumbar fusionQ48370655
Improved lumbar vertebral interbody fusion using rhOP-1: a comparison of autogenous bone graft, bovine hydroxylapatite (Bio-Oss), and BMP-7 (rhOP-1) in sheepQ50128375
Osteogenic protein-1 regulates insulin-like growth factor-I (IGF-I), IGF-II, and IGF-binding protein-5 (IGFBP-5) gene expression in fetal rat calvaria cells by different mechanisms.Q52190075
Osteogenic protein-1 is required for mammalian eye development.Q52202985
Clinical and radiographic outcomes of anterior lumbar interbody fusion using recombinant human bone morphogenetic protein-2.Q53666263
Augmentation of autograft using rhBMP-2 and different carrier media in the canine spinal fusion model.Q53960798
Donor site pain from the ilium. A complication of lumbar spine fusion.Q54347528
Response of bone marrow stroma cells to demineralized cortical bone matrix in experimental spinal fusion in rabbitsQ68136809
Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3-E1Q68186574
Experimental spinal fusion with decalcified bone matrix and deep-frozen allogeneic bone in rabbitsQ70224622
Effective doses of recombinant human bone morphogenetic protein-2 in experimental spinal fusionQ71729482
Expression pattern of osteogenic protein-1 (bone morphogenetic protein-7) in human and mouse developmentQ71746376
Experimental spinal fusion with recombinant human bone morphogenetic protein-2Q72062770
A prospective analysis of autograft versus allograft in posterolateral lumbar fusion in the same patient. A minimum of 1-year follow-up in 144 patientsQ72417723
In vivo evaluation of recombinant human osteogenic protein (rhOP-1) implants as a bone graft substitute for spinal fusionsQ72840259
Recombinant human bone morphogenetic protein-2 overcomes the inhibitory effect of ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), on posterolateral lumbar intertransverse process spine fusionQ73185913
OP-1 enhances dendritic growth from cerebral cortical neurons in vitroQ73343132
Osteogenic protein-1 mRNA in the uterine endometriumQ73381746
Experimental spinal fusion with recombinant human bone morphogenetic protein-2 without decortication of osseous elementsQ73455918
The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: a preliminary reportQ73511686
Osteogenic protein-1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblastsQ74172123
Laparoscopic anterior spinal arthrodesis with rhBMP-2 in a titanium interbody threaded cageQ74551626
Osteogenic protein versus autologous interbody arthrodesis in the sheep thoracic spine. A comparative endoscopic study using the Bagby and Kuslich interbody fusion deviceQ74668123
The use of recombinant human bone morphogenetic protein 2 (rhBMP-2) to promote spinal fusion in a nonhuman primate anterior interbody fusion modelQ77345165
Delivery of recombinant human bone morphogenetic protein-2 using a compression-resistant matrix in posterolateral spine fusion in the rabbit and in the non-human primateQ77627852
P433issue1
P921main subjectneurosurgeryQ188449
P304page(s)110-117
P577publication date2005-09-01
P1433published inHSS JournalQ5636001
P1476titleBone morphogenic proteins: applications in spinal surgery
P478volume1

Reverse relations

Q52647396Spinal Cord Stimulation, MILD Procedure, and Regenerative Medicine, Novel Interventional Nonopioid Therapies in Chronic Pain.cites workP2860

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