Osteogenic protein-1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblasts

scientific article published on 01 October 2000

Osteogenic protein-1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblasts is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/1097-4652(200010)185:1<87::AID-JCP8>3.0.CO;2-8
P698PubMed publication ID10942522

P2093author name stringLee JC
Yeh LC
Unda R
P2860cites workEffects of osteogenic protein-1 (OP-1, BMP-7) on bone matrix protein expression by fetal rat calvarial cells are differentiation stage specificQ71615015
Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healingQ72113443
The effects of bone morphogenetic protein-2, -4, and -6 on differentiation of rat osteoblast cells in vitroQ72237332
Temporal changes in matrix protein synthesis and mRNA expression during mineralized tissue formation by adult rat bone marrow cells in cultureQ72323067
Sequence and expression of bone morphogenetic protein 3 mRNA in prolonged cultures of fetal rat calvarial osteoblasts and in rat prostate adenocarcinoma PA III cellsQ72606347
Osteogenic protein-1 stimulates proliferation and differentiation of human bone cells in vitroQ72883412
Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblastsQ73153008
Effects of recombinant human bone morphogenetic protein-2 on differentiation of cells isolated from human bone, muscle, and skinQ77298531
Inhibition of BMP receptor synthesis by antisense oligonucleotides attenuates OP-1 action in primary cultures of fetal rat calvaria cellsQ77650562
Expression of bone morphogenetic proteins in fracture healingQ77902221
Novel regulators of bone formation: molecular clones and activitiesQ24297338
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Isolation and characterization of a cDNA encoding a human liver/bone/kidney-type alkaline phosphataseQ24629588
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Noggin, cartilage morphogenesis, and joint formation in the mammalian skeletonQ28272018
Enhanced expression of type I receptors for bone morphogenetic proteins during bone formationQ28275365
Distinct and overlapping patterns of localization of bone morphogenetic protein (BMP) family members and a BMP type II receptor during fracture healing in ratsQ28567049
Bone morphogenetic protein-3b (BMP-3b) gene expression is correlated with differentiation in rat calvarial osteoblastsQ28574981
Glucocorticoid-induced differentiation of fetal rat calvarial osteoblasts is mediated by bone morphogenetic protein-6Q28578463
Bone morphogenetic proteins: multifunctional regulators of vertebrate developmentQ29618986
Expression of collagen alpha1(I) mRNA variants during tooth and bone formation in the rat.Q30653068
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Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineageQ36235105
Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvariaQ36383313
Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine developmentQ36686718
Bone morphogenetic protein-4 regulates its own expression in cultured osteoblastsQ38316816
Osteogenic protein-1-mediated insulin-like growth factor gene expression in primary cultures of rat osteoblastic cells.Q38358684
Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressivaQ41174010
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Development expression of bone sialoprotein mRNA in rat mineralized connective tissuesQ46296937
Osteogenic protein-1 stimulates mRNA levels of BMP-6 and decreases mRNA levels of BMP-2 and -4 in human osteosarcoma cellsQ46711838
Regulation of insulin-like growth factor system components by osteogenic protein-1 in human bone cellsQ46856898
Bone morphogenetic proteins: from basic studies to clinical approachesQ47975683
Bone morphogenetic protein 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva.Q51105647
Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix.Q52241329
Tissue specificity and developmental expression of rat osteopontin.Q52254634
Further biochemical and molecular characterization of primary rat parietal bone cell culturesQ68102188
Bone morphogenetic protein-2 stimulates alkaline phosphatase activity and collagen synthesis in cultured osteoblastic cells, MC3T3-E1Q68186574
Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cellsQ68768271
Mineralized bone nodules formed in vitro from enzymatically released rat calvaria cell populationsQ70288592
P433issue1
P304page(s)87-97
P577publication date2000-10-01
P1433published inJournal of Cellular PhysiologyQ1524270
P1476titleOsteogenic protein-1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblasts
P478volume185

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cites work (P2860)
Q39399757Bone induction by recombinant human osteogenic protein-1 (hOP-1, BMP-7) in the primate Papio ursinus with expression of mRNA of gene products of the TGF-beta superfamily.
Q42003155Bone morphogenetic protein receptor in the osteogenic differentiation of rat bone marrow stromal cells
Q35842884Bone morphogenetic protein receptor type Ia localization causes increased BMP2 signaling in mice exhibiting increased peak bone mass phenotype
Q36823739Bone morphogenic proteins: applications in spinal surgery
Q28080649Calcium phosphate scaffolds combined with bone morphogenetic proteins or mesenchymal stem cells in bone tissue engineering
Q40731887Differential effects of osteogenic protein-1 (BMP-7) on gene expression of BMP and GDF family members during differentiation of the mouse MC615 chondrocyte cells
Q40676893Differentiation of murine preosteoblastic KS483 cells depends on autocrine bone morphogenetic protein signaling during all phases of osteoblast formation
Q79228715Effects of osteogenic protein‐1 (OP‐1, BMP‐7) on gene expression in cultured medial collateral ligament cells
Q82771853Endogenous BMPR-IB signaling is required for early osteoblast differentiation of human bone cells
Q49843883Genetic polymorphisms in bone morphogenetic protein receptor type IA gene predisposes individuals to ossification of the posterior longitudinal ligament of the cervical spine via the smad signaling pathway
Q39546765In vitro and in vivo studies on the effects of bone morphogenetic protein-7 on human kidney and lung tumor cells
Q40694532Osteogenic protein-1 (OP-1, BMP-7) induces osteoblastic cell differentiation of the pluripotent mesenchymal cell line C2C12.
Q77667115Osteogenic protein-1 and interleukin-6 with its soluble receptor synergistically stimulate rat osteoblastic cell differentiation
Q33252751Simultaneous gene transfer of bone morphogenetic protein (BMP) -2 and BMP-7 by in vivo electroporation induces rapid bone formation and BMP-4 expression
Q36605465Soluble and insoluble signals and the induction of bone formation: molecular therapeutics recapitulating development

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