Genetic polymorphisms in bone morphogenetic protein receptor type IA gene predisposes individuals to ossification of the posterior longitudinal ligament of the cervical spine via the smad signaling pathway

scientific article published on 20 February 2018

Genetic polymorphisms in bone morphogenetic protein receptor type IA gene predisposes individuals to ossification of the posterior longitudinal ligament of the cervical spine via the smad signaling pathway is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1101116824
P356DOI10.1186/S12891-018-1966-1
P932PMC publication ID5819076
P698PubMed publication ID29458345

P2093author name stringHao Wang
Haibin Li
Weitao Jin
P2860cites workEffect of bone morphogenetic proteins-4, -5 and -6 on DNA synthesis and expression of bone-related proteins in cultured human periodontal ligament cellsQ24310178
MADR1, a MAD-related protein that functions in BMP2 signaling pathwaysQ24317247
Cloning and characterization of a human type II receptor for bone morphogenetic proteinsQ24561622
Mechanism of activation of the TGF-beta receptorQ28245861
Bone morphogenetic protein receptors and signal transductionQ28258965
Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2Q28283345
Smads: transcriptional activators of TGF-beta responsesQ28292325
Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralizationQ34035649
Ossification of the posterior longitudinal ligament of the spine.Q34259858
Association of a BMP9 haplotype with ossification of the posterior longitudinal ligament (OPLL) in a Chinese populationQ34351033
Impaired calcification around matrix vesicles of growth plate and bone in alkaline phosphatase-deficient miceQ35094674
Genomic study of ossification of the posterior longitudinal ligament of the spineQ35103713
Bone morphogenetic protein receptors and activin receptors are highly expressed in ossified ligament tissues of patients with ossification of the posterior longitudinal ligament.Q35764296
Association of bone morphogenetic protein-2 gene polymorphisms with susceptibility to ossification of the posterior longitudinal ligament of the spine and its severity in Chinese patientsQ36743602
Myoblast sensitivity and fibroblast insensitivity to osteogenic conversion by BMP-2 correlates with the expression of Bmpr-1aQ37201038
Ossification of the posterior longitudinal ligament of the cervical spine: etiology and natural historyQ37965309
The Insertion/Deletion Polymorphism of Angiotensin I Converting Enzyme Gene is Associated With Ossification of the Posterior Longitudinal Ligament in the Korean PopulationQ38268644
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.Q38614636
Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2).Q40523512
Statistical notes for clinical researchers: post-hoc multiple comparisonsQ40679490
Smad5 and DPC4 are key molecules in mediating BMP-2-induced osteoblastic differentiation of the pluripotent mesenchymal precursor cell line C2C12.Q41069920
Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptorsQ41099665
Bone morphogenetic protein-9 induces PDLSCs osteogenic differentiation through the ERK and p38 signal pathwaysQ42795517
From mono- to oligo-Smads: the heart of the matter in TGF-beta signal transductionQ44087089
Association of VKORC1-1639G>A polymorphism with susceptibility to ossification of the posterior longitudinal ligament of the spine: a Korean studyQ44910401
Messenger RNA expression of the genes encoding receptors for bone morphogenetic protein (BMP) and transforming growth factor-β (TGF-β) in the cells from the posterior longitudinal ligament in cervical spineQ47774284
Association between BMP-2 and COL6A1 gene polymorphisms with susceptibility to ossification of the posterior longitudinal ligament of the cervical spine in Korean patients and family members.Q53286280
Association of NPP1 polymorphism with postoperative progression of ossification of the posterior longitudinal ligament in Chinese patients.Q54615119
Polymerase chain reactionQ68117653
Osteogenic protein-1 differentially regulates the mRNA expression of bone morphogenetic proteins and their receptors in primary cultures of osteoblastsQ74172123
A genome-wide association study identifies susceptibility loci for ossification of the posterior longitudinal ligament of the spineQ87448257
Posterior paravertebral ossification causing cervical myelopathy. A report of eighteen casesQ93759786
P433issue1
P921main subjectmorphogenesisQ815547
ossification of the posterior longitudinal ligamentQ11488367
P304page(s)61
P577publication date2018-02-20
P1433published inBMC Musculoskeletal DisordersQ15751716
P1476titleGenetic polymorphisms in bone morphogenetic protein receptor type IA gene predisposes individuals to ossification of the posterior longitudinal ligament of the cervical spine via the smad signaling pathway
P478volume19

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cites work (P2860)
Q92890559Degenerative cervical myelopathy - update and future directions
Q92853727Genetics of Degenerative Cervical Myelopathy: A Systematic Review and Meta-Analysis of Candidate Gene Studies
Q91668106Molecular Pathophysiology of Ossification of the Posterior Longitudinal Ligament (OPLL)

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