scholarly article | Q13442814 |
P2093 | author name string | J L Wrana | |
M Buchwald | |||
S J Tang | |||
M Macías-Silva | |||
P A Hoodless | |||
P2860 | cites work | Activation of signalling by the activin receptor complex | Q24308084 |
MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling | Q24310282 | ||
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4 | Q24314661 | ||
MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma | Q24315119 | ||
MADR1, a MAD-related protein that functions in BMP2 signaling pathways | Q24317247 | ||
Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors | Q24319747 | ||
Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse | Q46227290 | ||
A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway | Q46482720 | ||
Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily | Q48064097 | ||
MAD-related proteins in TGF-beta signalling. | Q52198314 | ||
Differential expression of inhibin subunits and follistatin, but not of activin receptor type II, during early murine embryonic development. | Q52229140 | ||
Induction of epidermis and inhibition of neural fate by Bmp-4 | Q52508863 | ||
Mad about SMADs | Q58983799 | ||
TGF beta signals through a heteromeric protein kinase receptor complex | Q24337608 | ||
Cloning and characterization of a human type II receptor for bone morphogenetic proteins | Q24561622 | ||
Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin | Q24612297 | ||
Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs | Q24651958 | ||
TGF-beta signalling from cell membrane to nucleus through SMAD proteins | Q28131770 | ||
The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling | Q28243202 | ||
Mechanism of activation of the TGF-beta receptor | Q28245861 | ||
Smad4 and FAST-1 in the assembly of activin-responsive factor | Q28248490 | ||
Characterization of type I receptors for transforming growth factor-beta and activin | Q28251169 | ||
Identification of type I and type II serine/threonine kinase receptors for growth/differentiation factor-5 | Q28284508 | ||
Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4 | Q28288976 | ||
Signal transduction by members of the transforming growth factor-beta superfamily | Q28303118 | ||
Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor | Q28507865 | ||
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2 | Q28511063 | ||
Novel activin receptors: distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors | Q28512760 | ||
Cloning and characterization of a transmembrane serine kinase that acts as an activin type I receptor | Q28580056 | ||
Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase | Q28584256 | ||
The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase | Q28628494 | ||
Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling | Q28631440 | ||
Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components | Q29036482 | ||
A transcriptional partner for MAD proteins in TGF-beta signalling | Q29622823 | ||
XSmad2 directly activates the activin-inducible, dorsal mesoderm gene XFKH1 in Xenopus embryos. | Q32172187 | ||
A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity | Q33886942 | ||
Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects | Q36235769 | ||
Two distinct transmembrane serine/threonine kinases from Drosophila melanogaster form an activin receptor complex | Q36645287 | ||
Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. | Q36665327 | ||
Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development | Q36686718 | ||
TGF-beta signalling through the Smad pathway | Q36914476 | ||
Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth | Q37378595 | ||
Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway | Q38349140 | ||
TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling | Q41083690 | ||
Smad1 and smad5 act downstream of intracellular signalings of BMP-2 that inhibits myogenic differentiation and induces osteoblast differentiation in C2C12 myoblasts | Q41090627 | ||
Msx2 is a transcriptional regulator in the BMP4-mediated programmed cell death pathway | Q41104494 | ||
Inhibitory control of neural differentiation in mammalian cells | Q41111139 | ||
Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family | Q41358724 | ||
In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria | Q41387920 | ||
Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo | Q41436510 | ||
Activin/EDF as an inhibitor of neural differentiation. | Q41714120 | ||
Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction | Q44507413 | ||
P433 | issue | 40 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 25628-36 | |
P577 | publication date | 1998-10-02 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2 | |
P478 | volume | 273 |
Q28203670 | A Role for BMP Heterodimers in Roof Plate-Mediated Repulsion of Commissural Axons |
Q22003817 | A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation |
Q28141283 | A Smad transcriptional corepressor |
Q34990909 | A clinical and experimental overview of sirenomelia: insight into the mechanisms of congenital limb malformations. |
Q21284180 | A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs). |
Q36288327 | A pair of transmembrane receptors essential for the retention and pigmentation of hair |
Q33229597 | A road map toward defining the role of Smad signaling in hematopoietic stem cells |
Q27643809 | A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor |
Q34211818 | ACVR1 p.Q207E causes classic fibrodysplasia ossificans progressiva and is functionally distinct from the engineered constitutively active ACVR1 p.Q207D variant |
Q54248766 | ACVR1R206H receptor mutation causes fibrodysplasia ossificans progressiva by imparting responsiveness to activin A. |
Q35127963 | ALK1 as an emerging target for antiangiogenic therapy of cancer |
Q30811602 | ALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expression |
Q28144663 | Activation of Smad1-mediated transcription by p300/CBP |
Q38298464 | Activation of the TGF-beta/activin-Smad2 pathway during allergic airway inflammation |
Q96220920 | Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop |
Q46852208 | Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I. |
Q24321895 | Activin receptor-like kinase 1 is implicated in the maturation phase of angiogenesis |
Q24677057 | Activin receptor-like kinase 1 modulates transforming growth factor-beta 1 signaling in the regulation of angiogenesis |
Q46377767 | Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation |
Q22254570 | Activin receptor-like kinase 2 can mediate atrioventricular cushion transformation |
Q40819395 | Activin receptors are expressed on human lung fibroblast and activin A facilitates fibroblast-mediated collagen gel contraction |
Q34038590 | Activin signal transduction pathways |
Q33753080 | AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity. |
Q27682737 | An Activin A/BMP2 Chimera, AB204, Displays Bone-Healing Properties Superior to Those of BMP2 |
Q34006810 | An Activin A/BMP2 chimera, AB215, blocks estrogen signaling via induction of ID proteins in breast cancer cells |
Q34307660 | An emerging role for co-receptors in inhibin signal transduction |
Q37089050 | An investigation of BMP-7 mediated alterations to BMP signalling components in human tenocyte-like cells |
Q39965669 | Analysis of the contribution of receptor subdomains to the cooperative binding and internalization of transforming growth factor-beta (TGF-beta) type I and type II receptors |
Q48302210 | Animal models of fibrodysplasia ossificans progressiva. |
Q42506970 | Antitumor activity of ALK1 in pancreatic carcinoma cells |
Q24647244 | Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways |
Q28507415 | Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart |
Q38294847 | Autoregulation of Xvent-2B; direct interaction and functional cooperation of Xvent-2 and Smad1. |
Q28586282 | BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning |
Q36639706 | BMP signaling and spadetail regulate exit of muscle precursors from the zebrafish tailbud |
Q36659526 | BMP signaling in the cartilage growth plate. |
Q37849623 | BMP signaling in the nephron progenitor niche |
Q37776859 | BMP signaling in vascular development and disease |
Q35024134 | BMP signaling is required for cell cleavage in preimplantation-mouse embryos |
Q28507228 | BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo |
Q24611307 | BMP type I receptor inhibition reduces heterotopic [corrected] ossification |
Q24631766 | BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II |
Q24328930 | BMP-2/4 and BMP-6/7 differentially utilize cell surface receptors to induce osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells |
Q40221971 | BMP-dependent activation of caspase-9 and caspase-8 mediates apoptosis in pulmonary artery smooth muscle cells |
Q40498143 | BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways |
Q52142757 | BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways. |
Q28585269 | BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling |
Q42951218 | BMP7 signaling via BMPR1A, BMPR1B inhibits the proliferation of lung large carcinoma NCI-H460 cell |
Q42445316 | BMPs and BMPRs in chicken ovary and effects of BMP-4 and -7 on granulosa cell proliferation and progesterone production in vitro |
Q43144441 | Bmp inhibition is necessary for post-gastrulation patterning and morphogenesis of the zebrafish tailbud |
Q24555732 | Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo |
Q37947050 | Bone Morphogenetic Protein functions as a context-dependent angiogenic cue in vertebrates |
Q36466135 | Bone Morphogenetic Protein-2 (BMP-2) Activates NFATc1 Transcription Factor via an Autoregulatory Loop Involving Smad/Akt/Ca2+ Signaling |
Q33968772 | Bone morphogenetic protein (BMP)-4 and BMP-7 regulate differentially transforming growth factor (TGF)-beta1 in normal human lung fibroblasts (NHLF). |
Q38354930 | Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis |
Q36325743 | Bone morphogenetic protein receptor signaling is necessary for normal murine postnatal bone formation |
Q34068835 | Bone morphogenetic protein signaling and growth suppression in colon cancer |
Q24316099 | Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression |
Q44301578 | Bone morphogenetic protein signaling in articular chondrocyte differentiation |
Q26822802 | Bone morphogenetic protein signaling in nephron progenitor cells |
Q42025588 | Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes |
Q44533976 | Bone morphogenetic protein signalling in NGF-stimulated PC12 cells |
Q28141605 | Bone morphogenetic protein-3 is a negative regulator of bone density |
Q40007492 | Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LbetaT2 gonadotrophs |
Q73821820 | Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro |
Q36933692 | Bone morphogenic protein signaling is a major determinant of dentate development |
Q33804968 | CD44 and hyaluronan promote the bone morphogenetic protein 7 signaling response in murine chondrocytes |
Q36321864 | CD44 modulates Smad1 activation in the BMP-7 signaling pathway |
Q27347461 | Caenorhabditis elegans SMA-10/LRIG is a conserved transmembrane protein that enhances bone morphogenetic protein signaling |
Q41912514 | Casein kinase II contributes to the synergistic effects of BMP7 and BDNF on Smad 1/5/8 phosphorylation in septal neurons under hypoglycemic stress |
Q34681356 | Characterization of a bone morphogenetic protein-responsive Smad-binding element |
Q30976369 | Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues |
Q47919138 | Characterization of zebrafish smad1, smad2 and smad5: the amino-terminus of smad1 and smad5 is required for specific function in the embryo. |
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Q38332721 | Conditional BMP inhibition in Xenopus reveals stage-specific roles for BMPs in neural and neural crest induction |
Q35025212 | Consequences of knocking out BMP signaling in the mouse |
Q36978228 | Constitutively active ALK2 receptor mutants require type II receptor cooperation |
Q38659223 | Control of Adult Neurogenesis by Short-Range Morphogenic-Signaling Molecules |
Q35563823 | Control of endocardial cushion and cardiac valve maturation by BMP signaling pathways |
Q37641781 | Control of the bone morphogenetic protein 7 gene in developmental and adult life |
Q39791091 | Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads |
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Q24292510 | Cripto-1 activates nodal- and ALK4-dependent and -independent signaling pathways in mammary epithelial Cells |
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Q42395321 | Dedifferentiation of human articular chondrocytes is associated with alterations in expression patterns of GDF-5 and its receptors |
Q28142906 | Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells |
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Q50525535 | Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys. |
Q35498717 | Distinct bone morphogenetic proteins activate indistinguishable transcriptional responses in nephron epithelia including Notch target genes. |
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