Proteasomal degradation of Smad1 induced by bone morphogenetic proteins

scientific article published in December 2001

Proteasomal degradation of Smad1 induced by bone morphogenetic proteins is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M105500200
P698PubMed publication ID11571290
P5875ResearchGate publication ID11777553

P2093author name stringWang T
Lin Y
Farley J
Gruendler C
P2860cites workA SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formationQ22003817
TGF-beta signal transductionQ22003891
Negative feedback regulation of TGF-beta signaling by the SnoN oncoproteinQ22010706
Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signalingQ24290353
Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligaseQ24290743
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradationQ24290777
Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradationQ24291000
Specific interaction of type I receptors of the TGF-beta family with the immunophilin FKBP-12Q24305896
MADR1, a MAD-related protein that functions in BMP2 signaling pathwaysQ24317247
Serine phosphorylation, chromosomal localization, and transforming growth factor-beta signal transduction by human bsp-1Q24322007
Structure and functions of the 20S and 26S proteasomesQ24328777
Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assemblyQ27931608
Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizymeQ28117992
TGF-beta signalling from cell membrane to nucleus through SMAD proteinsQ28131770
Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2Q28283345
Smads: transcriptional activators of TGF-beta responsesQ28292325
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signalingQ28608960
Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway componentsQ29036482
Bone morphogenetic proteins: multifunctional regulators of vertebrate developmentQ29618986
Regulation of Smad activityQ33830190
ATP-Dependent inactivation and sequestration of ornithine decarboxylase by the 26S proteasome are prerequisites for degradationQ33959864
The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organismsQ34349039
Regulation of cartilage and bone differentiation by bone morphogenetic proteinsQ35455538
The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducersQ35843521
Cloning and characterization of mouse Lmp3 cDNA, encoding a proteasome beta subunitQ36867421
Ubiquitin-dependent degradation of TGF-beta-activated smad2.Q40913405
Mechanism of TGFbeta receptor inhibition by FKBP12Q41101968
Effects on NF-kappa B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasomeQ41197961
Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitinationQ41589996
SMADs: mediators and regulators of TGF-beta signalingQ41732765
Processing of N3, a mammalian proteasome beta-type subunitQ42111030
Distinct domains of antizyme required for binding and proteolysis of ornithine decarboxylaseQ42267971
The N terminus of antizyme promotes degradation of heterologous proteinsQ46207297
TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteinsQ47851514
MAD-related proteins in TGF-beta signalling.Q52198314
The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.Q52549447
P433issue49
P407language of work or nameEnglishQ1860
P921main subjectmorphogenesisQ815547
P304page(s)46533-46543
P577publication date2001-12-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleProteasomal degradation of Smad1 induced by bone morphogenetic proteins
P478volume276

Reverse relations

cites work (P2860)
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