scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1002610033 |
P356 | DOI | 10.1038/NCB1870 |
P932 | PMC publication ID | 2757091 |
P698 | PubMed publication ID | 19377468 |
P5875 | ResearchGate publication ID | 24308405 |
P2093 | author name string | Mary C Mullins | |
Shawn C Little | |||
P2860 | cites work | p53 activation by knockdown technologies | Q21563456 |
Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms | Q24291289 | ||
The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4 | Q24315313 | ||
Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptors | Q24548576 | ||
BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II | Q24631766 | ||
The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals | Q24645277 | ||
Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution | Q27617482 | ||
The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly | Q27640861 | ||
A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor | Q27643809 | ||
Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2 | Q28283345 | ||
Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily | Q28292733 | ||
Potent ectopic bone-inducing activity of bone morphogenetic protein-4/7 heterodimer | Q28302203 | ||
Effective targeted gene 'knockdown' in zebrafish | Q29547445 | ||
Specificity and versatility in tgf-beta signaling through Smads | Q29616324 | ||
The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo | Q32061709 | ||
Lost-a-fin encodes a type I BMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation. | Q32061711 | ||
BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development | Q33889312 | ||
Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway. | Q33890835 | ||
Spemann's organizer and self-regulation in amphibian embryos | Q33993579 | ||
Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. | Q34391928 | ||
BMP signaling and early embryonic patterning. | Q34416108 | ||
Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity | Q34445698 | ||
Oligomeric structure of type I and type II transforming growth factor beta receptors: homodimers form in the ER and persist at the plasma membrane | Q36276659 | ||
Shaping BMP morphogen gradients in the Drosophila embryo and pupal wing. | Q36348381 | ||
Extracellular modulation of BMP activity in patterning the dorsoventral axis. | Q36633269 | ||
Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. | Q36665327 | ||
Spatial bistability of Dpp-receptor interactions during Drosophila dorsal-ventral patterning. | Q40439096 | ||
Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo | Q41436510 | ||
The zebrafish gene map defines ancestral vertebrate chromosomes | Q42069288 | ||
The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axis | Q43074864 | ||
Morpholino phenocopies of the bmp2b/swirl and bmp7/snailhouse mutations | Q43690954 | ||
Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning. | Q45138646 | ||
Depletion of three BMP antagonists from Spemann's organizer leads to a catastrophic loss of dorsal structures | Q46073558 | ||
Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo | Q47071657 | ||
zALK-8, a novel type I serine/threonine kinase receptor, is expressed throughout early zebrafish development | Q47073607 | ||
Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes | Q47073791 | ||
Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity | Q47073908 | ||
Ventral and lateral regions of the zebrafish gastrula, including the neural crest progenitors, are established by a bmp2b/swirl pathway of genes | Q47073994 | ||
Ventral mesoderm induction and patterning by bone morphogenetic protein heterodimers in Xenopus embryos | Q47890993 | ||
In vivo analysis using variants of zebrafish BMPR-IA: range of action and involvement of BMP in ectoderm patterning. | Q48004761 | ||
Restricted expression of the receptor serine/threonine kinase BMPR-IB in zebrafish | Q48195101 | ||
Equivalent genetic roles for bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation. | Q52171177 | ||
Creating seamless junctions independent of restriction sites in PCR cloning | Q71069220 | ||
Regulation of epidermal induction by BMP2 and BMP7 signaling | Q73661145 | ||
P433 | issue | 5 | |
P921 | main subject | morphogenesis | Q815547 |
BMP receptor complex | Q21095329 | ||
Bone morphogenetic protein 2b | Q56252047 | ||
P304 | page(s) | 637-643 | |
P577 | publication date | 2009-04-19 | |
P1433 | published in | Nature Cell Biology | Q1574111 |
P1476 | title | Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis | |
P478 | volume | 11 |
Q63976740 | A familial congenital heart disease with a possible multigenic origin involving a mutation in BMPR1A |
Q54107804 | A heterodimer formed by bone morphogenetic protein 9 (BMP9) and BMP10 provides most BMP biological activity in plasma. |
Q34694765 | ALK2 mutation in a patient with Down's syndrome and a congenital heart defect |
Q33753080 | AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity. |
Q38896053 | Agonists and Antagonists of TGF-β Family Ligands |
Q35568492 | Alk2 regulates early chondrogenic fate in fibrodysplasia ossificans progressiva heterotopic endochondral ossification |
Q38945280 | Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein-Induced Retinal Angiogenesis |
Q37671260 | Alk3/Alk3b and Smad5 mediate BMP signaling during lymphatic development in zebrafish |
Q28591841 | Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities |
Q30885621 | Applications of small molecule BMP inhibitors in physiology and disease |
Q33576759 | B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo |
Q47237512 | BMP Signalling at the Crossroad of Liver Fibrosis and Regeneration. |
Q38114048 | BMP signaling in telencephalic neural cell specification and maturation |
Q37776859 | BMP signaling in vascular development and disease |
Q34293026 | BMP type II receptors have redundant roles in the regulation of hepatic hepcidin gene expression and iron metabolism |
Q38364243 | BMP/Smad signaling and embryonic cerebellum development: stem cell specification and heterogeneity of anterior rhombic lip. |
Q83227908 | BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian embryogenesis |
Q27336050 | Bmp and nodal independently regulate lefty1 expression to maintain unilateral nodal activity during left-right axis specification in zebrafish |
Q42027007 | Bmp signaling exerts opposite effects on cardiac differentiation |
Q38620893 | Bmp2 controls iron homeostasis in mice independent of Bmp6. |
Q35596542 | Bmp2 is required for odontoblast differentiation and pulp vasculogenesis |
Q26746964 | Bone Morphogenetic Protein 4 Signalling in Neural Stem and Progenitor Cells during Development and after Injury |
Q37947050 | Bone Morphogenetic Protein functions as a context-dependent angiogenic cue in vertebrates |
Q37801468 | Bone Morphogenetic Proteins: A critical review |
Q33719268 | Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos |
Q92823639 | Chemotropic signaling by BMP7 requires selective interaction at a key residue in ActRIIA |
Q43568308 | Cleavage of the Drosophila screw prodomain is critical for a dynamic BMP morphogen gradient in embryogenesis. |
Q42332006 | Clinical significance linked to functional defects in bone morphogenetic protein type 2 receptor, BMPR2. |
Q30378791 | Comparative analysis of zebrafish bone morphogenetic proteins 2, 4 and 16: molecular and evolutionary perspectives. |
Q30457781 | Construction of a vertebrate embryo from two opposing morphogen gradients |
Q40885406 | Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2. |
Q52593116 | Contextual determinants of TGFβ action in development, immunity and cancer. |
Q36093011 | Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality |
Q35896949 | Differential requirement of bone morphogenetic protein receptors Ia (ALK3) and Ib (ALK6) in early embryonic patterning and neural crest development |
Q39674487 | Differentiation of pre-osteoblast cells on poly(ethylene terephthalate) grafted with RGD and/or BMPs mimetic peptides |
Q24312010 | Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning |
Q38233800 | Diversity is in my veins: role of bone morphogenetic protein signaling during venous morphogenesis in zebrafish illustrates the heterogeneity within endothelial cells |
Q38538339 | EMBRYO DEVELOPMENT. BMP gradients: A paradigm for morphogen-mediated developmental patterning |
Q38928611 | Emerging roles of the bone morphogenetic protein pathway in cancer: potential therapeutic target for kinase inhibition |
Q91509651 | Endothelial Bmp2 knockout exacerbates hemochromatosis in Hfe knockout mice but not Bmp6 knockout mice |
Q37214103 | Establishment of Immortalized Mouse Bmp2 Knock-Out Dental Papilla Mesenchymal Cells Necessary for Study of Odontoblastic Differentiation and Odontogenesis |
Q51907374 | Evolution of extracellular Dpp modulators in insects: The roles of tolloid and twisted-gastrulation in dorsoventral patterning of the Tribolium embryo. |
Q35813719 | Fibrodysplasia ossificans progressiva: a human genetic disorder of extraskeletal bone formation, or--how does one tissue become another? |
Q34644842 | Fibrodysplasia ossificans progressiva: mechanisms and models of skeletal metamorphosis |
Q27026644 | Fine-tuned shuttles for bone morphogenetic proteins |
Q47160037 | Gdf3 is required for robust Nodal signaling during germ layer formation and left-right patterning |
Q45958654 | Gdf6a is required for the initiation of dorsal-ventral retinal patterning and lens development. |
Q33892590 | Genetic analysis reveals an unexpected role of BMP7 in initiation of ureteric bud outgrowth in mouse embryos |
Q36981608 | Granting immunity to FOP and catching heterotopic ossification in the Act. |
Q47094799 | Heterodimers reign in the embryo |
Q35582686 | Inductive specification and axonal orientation of spinal neurons mediated by divergent bone morphogenetic protein signaling pathways |
Q35075368 | Influence of bone morphogenetic protein type IA receptor conditional knockout in lens on expression of bone morphogenetic protein 4 in lens |
Q36552107 | Inherited human diseases of heterotopic bone formation |
Q33605524 | Integration of BMP and Wnt signaling via vertebrate Smad1/5/8 and Drosophila Mad. |
Q27670456 | Latent TGF-β structure and activation |
Q37971729 | Life is a pattern: vascular assembly within the embryo |
Q58605164 | Liver iron sensing and body iron homeostasis |
Q90218690 | Marcksb plays a key role in the secretory pathway of zebrafish Bmp2b |
Q47417320 | Maternal Gdf3 is an obligatory cofactor in Nodal signaling for embryonic axis formation in zebrafish. |
Q42918575 | Meeting report - TGF-β superfamily: signaling in development and disease |
Q35164712 | Mutation in the type IB bone morphogenetic protein receptor Alk6b impairs germ-cell differentiation and causes germ-cell tumors in zebrafish |
Q35983621 | Mutually inductive interactions between the lens and retina require ALK3 functions during mouse embryonic development |
Q34651389 | Negative feedback regulation of Wnt signaling via N-linked fucosylation in zebrafish |
Q28069613 | Oocyte-somatic cell interactions in the human ovary-novel role of bone morphogenetic proteins and growth differentiation factors |
Q33808497 | Organizer-derived Bmp2 is required for the formation of a correct Bmp activity gradient during embryonic development |
Q35483789 | Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice |
Q47434187 | Prodomain-Growth Factor Swapping in the Structure of pro-TGF-β1. |
Q33750470 | Rapid evolution of a novel signalling mechanism by concerted duplication and divergence of a BMP ligand and its extracellular modulators |
Q50042943 | Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing. |
Q38019713 | Spatial regulation of BMP activity |
Q91812737 | Specification of BMP Signaling |
Q91943837 | Specificity, versatility, and control of TGF-β family signaling |
Q36743865 | Split top: a maternal cathepsin B that regulates dorsoventral patterning and morphogenesis |
Q33756401 | Strategies for exploring TGF-β signaling in Drosophila |
Q38957057 | Structural Biology and Evolution of the TGF-β Family |
Q90633876 | Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family |
Q38615917 | Systems biology derived source-sink mechanism of BMP gradient formation |
Q38733048 | TGF-β Family Signaling in Early Vertebrate Development |
Q90631766 | TGF-β Signaling |
Q38824306 | TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology |
Q26783734 | Targeting BMP signalling in cardiovascular disease and anaemia |
Q26827564 | Temporally coordinated signals progressively pattern the anteroposterior and dorsoventral body axes |
Q89737690 | The BMP ligand Pinhead together with Admp supports the robustness of embryonic patterning |
Q34020080 | The FOP metamorphogene encodes a novel type I receptor that dysregulates BMP signaling |
Q92923287 | The Role of Bone Morphogenetic Protein 7 (BMP-7) in Inflammation in Heart Diseases |
Q47279346 | The TGFβ superfamily in Lisbon: navigating through development and disease |
Q37403100 | The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization |
Q27320128 | The integrator complex subunit 6 (Ints6) confines the dorsal organizer in vertebrate embryogenesis |
Q38106873 | The multiple activities of BMPs during spinal cord development. |
Q35590158 | The prodomain of BMP4 is necessary and sufficient to generate stable BMP4/7 heterodimers with enhanced bioactivity in vivo |
Q27656789 | The structure of myostatin:follistatin 288: insights into receptor utilization and heparin binding |
Q30567347 | The ventral to dorsal BMP activity gradient in the early zebrafish embryo is determined by graded expression of BMP ligands |
Q41063018 | Tissue-specific regulation of BMP signaling by Drosophila N-glycanase 1. |
Q37296203 | Up-regulation of BMP-2 antagonizes TGF-β1/ROCK-enhanced cardiac fibrotic signalling through activation of Smurf1/Smad6 complex |
Q47447929 | Variable signaling activity by FOP ACVR1 mutations |
Q50144496 | Variant BMP receptor mutations causing fibrodysplasia ossificans progressiva (FOP) in humans show BMP ligand-independent receptor activation in zebrafish |
Q47775830 | Vegetally localised Vrtn functions as a novel repressor to modulate bmp2b transcription during dorsoventral patterning in zebrafish. |
Q61443332 | Venous identity requires BMP signalling through ALK3 |
Q47135848 | Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm |
Q33820568 | Zebrafish chordin-like and chordin are functionally redundant in regulating patterning of the dorsoventral axis |
Q39976632 | Zygotic LvBMP5-8 is required for skeletal patterning and for left-right but not dorsal-ventral specification in the sea urchin embryo. |
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