N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes

scientific article published on 6 March 2013

N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BCMD.2013.02.004
P932PMC publication ID3646938
P698PubMed publication ID23481459

P50authorChristian A. HübnerQ110571513
P2093author name stringSeth L Alper
Marie Trudel
Alicia Rivera
Boris E Shmukler
Jessica Alves
Marco B Rust
Ann Hsu
P2860cites workDrugs for preventing red blood cell dehydration in people with sickle cell diseaseQ24202032
TRP channel activation by reversible covalent modificationQ24677242
Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporterQ28140515
Modulation of Gardos channel activity by oxidants and oxygen tension: effects of 1-chloro-2,4-dinitrobenzene and phenazine methosulphateQ28252303
Activation of electroneutral K flux in Amphiuma red blood cells by N-ethylmaleimide. Distinction between K/H exchange and KCl cotransportQ28383401
Phospholipase C in Living CellsQ29303618
Small-molecule screen identifies inhibitors of the neuronal K-Cl cotransporter KCC2Q33417208
Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytesQ33525570
Sites of regulated phosphorylation that control K-Cl cotransporter activityQ33609638
Mouse K-Cl cotransporter KCC1: cloning, mapping, pathological expression, and functional regulationQ33880558
The risks and benefits of long-term use of hydroxyurea in sickle cell anemia: A 17.5 year follow-upQ33890227
The KCl cotransporter isoform KCC3 can play an important role in cell growth regulationQ33952170
A dominant negative mutant of the KCC1 K-Cl cotransporter: both N- and C-terminal cytoplasmic domains are required for K-Cl cotransport activity.Q34090855
K-Cl cotransport: properties and molecular mechanismQ34110131
Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics.Q34139852
Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease.Q34140614
K+(Na+)/H+ exchange in human erythrocytes activated under low ionic strength conditionsQ34254375
Unconventional chemiosmotic coupling of NHA2, a mammalian Na+/H+ antiporter, to a plasma membrane H+ gradientQ34297529
Control of erythrocyte membrane-skeletal cohesion by the spectrin-membrane linkageQ34664087
Oxidative modification of M-type K(+) channels as a mechanism of cytoprotective neuronal silencingQ35102221
Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell miceQ35140955
Novel therapies for prevention of erythrocyte dehydration in sickle cell anemia.Q35159778
Calpain (Ca(2+)-dependent thiol protease) in erythrocytes of young and old individualsQ35670079
Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD miceQ35785736
Evidence for a protective role of the Gardos channel against hemolysis in murine spherocytosisQ35848022
Towards a transgenic mouse model of sickle cell disease: hemoglobin SAD.Q35932701
Ion transport pathology in the mechanism of sickle cell dehydrationQ35993299
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencingQ37102932
Twenty-five years of K-Cl cotransport: from stimulation by a thiol reaction to cloning of the full-length KCCs.Q37252135
Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell diseaseQ37352493
Determinants of erythrocyte hydrationQ37698164
A potent oral P-selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell diseaseQ38001297
Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivativesQ40333068
Inhibitors of the K+(Na+)/H+ exchanger of human red blood cellsQ41914283
Mouse models for studying pain in sickle disease: effects of strain, age, and acutenessQ41996084
K:CI cotransport in red cells of transgenic mice expressing high levels of human hemoglobin SQ42440578
Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytesQ43666378
Improvements in haemolysis and indicators of erythrocyte survival do not correlate with acute vaso-occlusive crises in patients with sickle cell disease: a phase III randomized, placebo-controlled, double-blind study of the Gardos channel blocker seQ44020318
Complex effects of sulfhydryl reagents on ligand interactions with nucleoside transporters: evidence for multiple populations of ENT1 transporters with differential sensitivities to N-ethylmaleimideQ44025438
ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD miceQ44217786
Effect of 1-chloro-2,4-dinitrobenzene on K+ transport in normal and sickle human red blood cellsQ44308498
Heterotrimeric G protein Giis involved in a signal transduction pathway for ATP release from erythrocytesQ44654252
Single-channel analysis of KCNQ K+ channels reveals the mechanism of augmentation by a cysteine-modifying reagent.Q44919580
Pharmacology of the human red cell voltage-dependent cation channel. Part II: inactivation and blockingQ45140429
Effect of peroxynitrite on passive K+ transport in human red blood cellsQ46613456
Antibiotic effects on SO4(2-) uptake in human erythrocytesQ46909101
cDNA cloning and functional characterization of the mouse Ca2+-gated K+ channel, mIK1. Roles in regulatory volume decrease and erythroid differentiation.Q47682481
Transgenic mice and hemoglobinopathiesQ47926215
Erythrocyte density in sickle cell syndromes is associated with specific clinical manifestations and hemolysis.Q50504802
Sulphydryl modifications alter scramblase activity in murine sickle cell disease.Q50736132
Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4.Q50787662
Inhibition by divalent cations and sulphydryl reagents of the passive Ca2+ transport in human red blood cells observed in the presence of vanadate.Q54146586
Sulfhydryl oxidation and activation of red cell K(+)-Cl- cotransport in the transgenic SAD mouse.Q54162065
Cation transport in mouse erythrocytes: role of K(+)-Cl- cotransport in regulatory volume decrease.Q54176201
Senicapoc trial results support the existence of different sub-phenotypes of sickle cell disease with possible drug-induced phenotypic shiftsQ57624742
SHP-1 Tyrosine Phosphatase in Human ErythrocytesQ61873352
Factors affecting the activation and inactivation of KCl cotransport in 'young' human red cellsQ68887635
Activation mechanism of calcium-activated neutral protease. Evidence for the existence of intramolecular and intermolecular autolysesQ69844488
Regulation of erythrocyte cation and water content in sickle cell anemiaQ70037500
Passive cation transport in hereditary xerocytosisQ70599762
Modulation of Ca2+ channels by PTX-sensitive G-proteins is blocked by N-ethylmaleimide in rat sympathetic neuronsQ71657344
N-ethylmaleimide discriminates between two lysine transport systems in human erythrocytesQ72641204
Stimulation of human erythrocyte K-Cl cotransport and protein phosphatase type 2A by n-ethylmaleimide: role of intracellular Mg++Q72996869
The relationship between hypotonically-induced taurine and K fluxes in trout red blood cellsQ74211820
Kinetics of Cl-dependent K influx in human erythrocytes with and without external Na: effect of NEMQ93642458
P433issue1
P304page(s)9-16
P577publication date2013-03-06
P1433published inBlood Cells, Molecules and DiseasesQ15758051
P1476titleN-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes
P478volume51

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