A tyrosine-to-histidine switch at position 18 of the Ross River virus E2 glycoprotein is a determinant of virus fitness in disparate hosts

scientific article published on 20 March 2013

A tyrosine-to-histidine switch at position 18 of the Ross River virus E2 glycoprotein is a determinant of virus fitness in disparate hosts is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.03326-12
P932PMC publication ID3648194
P698PubMed publication ID23514884

P50authorDavid W HawmanQ97635567
P2093author name stringThomas E Morrison
Lauren Oko
Melisa Medina-Rivera
Henri J Jupille
P2860cites workMembrane protein lateral interactions control Semliki Forest virus budding.Q40791064
O'nyong-nyong fever: an epidemic virus disease in East Africa. II. Isolation and some properties of the virusQ40995017
The Semliki Forest virus E2 gene as a virulence determinantQ41390376
Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse modelQ42157593
Ross river virus 26 S RNA: Complete nucleotide sequence and deduced sequence of the encoded structural proteinsQ42665587
An amino acid change in the exodomain of the E2 protein of Sindbis virus, which impairs the release of virus from chicken cells but not from mosquito cellsQ42995774
pK values of the ionizable groups of proteinsQ43043653
A single amino acid change in the E2 spike protein of a virulent strain of Semliki Forest virus attenuates pathogenicityQ43935939
Infectious RNA transcripts from Ross River virus cDNA clones and the construction and characterization of defined chimeras with Sindbis virus.Q44143039
Mutations in the E2 glycoprotein of Venezuelan equine encephalitis virus confer heparan sulfate interaction, low morbidity, and rapid clearance from blood of miceQ45740291
Detection of viral ribonucleic acid and histologic analysis of inflamed synovium in Ross River virus infectionQ45744149
Attenuating mutations in the E2 glycoprotein gene of Venezuelan equine encephalitis virus: construction of single and multiple mutants in a full-length cDNA cloneQ45852646
Two mutations in the envelope glycoprotein E2 of semliki forest virus affecting the maturation and entry patterns of the virus alter pathogenicity for miceQ45861578
The inflammatory response in the synovium of a patient with Ross River arbovirus infectionQ70108598
Cytology of synovial effusions in epidemic polyarthritisQ72017299
Human muscle satellite cells as targets of Chikungunya virus infectionQ21562321
Present and future arboviral threatsQ24289450
Ross River virus transmission, infection, and disease: a cross-disciplinary reviewQ24550672
Complement contributes to inflammatory tissue destruction in a mouse model of Ross River virus-induced diseaseQ24682922
An Amino Acid Substitution in the Coding Region of the E2 Glycoprotein Adapts Ross River Virus To Utilize Heparan Sulfate as an Attachment MoietyQ27469810
Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusionQ27485039
Molecular basis of Sindbis virus neurovirulence in miceQ27486828
An Outbreak of Ross River Virus Disease in Southwestern AustraliaQ27487892
Role of Conserved Histidine Residues in the Low-pH Dependence of the Semliki Forest Virus Fusion ProteinQ27488309
A structural and functional perspective of alphavirus replication and assemblyQ27490173
E1 Mutants Identify a Critical Region in the Trimer Interface of the Semliki Forest Virus Fusion ProteinQ27490331
Structural changes of envelope proteins during alphavirus fusionQ27666145
Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallographyQ27666147
Genome-scale phylogeny of the alphavirus genus suggests a marine originQ28255956
Infection with chikungunya virus in Italy: an outbreak in a temperate regionQ29346487
Changing patterns of chikungunya virus: re-emergence of a zoonotic arbovirusQ29620003
Persistent chronic inflammation and infection by Chikungunya arthritogenic alphavirus in spite of a robust host immune responseQ34110965
Heparin binding sites on Ross River virus revealed by electron cryo-microscopyQ34124532
Mannose binding lectin is required for alphavirus-induced arthritis/myositisQ34211498
Chikungunya disease: infection-associated markers from the acute to the chronic phase of arbovirus-induced arthralgiaQ34222718
Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoproteinQ34264257
Arthritogenic alphaviruses--an overviewQ34273343
Characterization of Ross River virus tropism and virus-induced inflammation in a mouse model of viral arthritis and myositisQ34301840
A single mutation in the E2 glycoprotein important for neurovirulence influences binding of sindbis virus to neuroblastoma cellsQ34340083
Host alternation of chikungunya virus increases fitness while restricting population diversity and adaptability to novel selective pressuresQ34485363
Chikungunya virus emergence is constrained in Asia by lineage-specific adaptive landscapesQ34977748
Novel chikungunya virus variant in travelers returning from Indian Ocean islandsQ35792249
Mutating conserved cysteines in the alphavirus e2 glycoprotein causes virus-specific assembly defectsQ35826350
Chikungunya virus, southeastern FranceQ35876743
Interferon-alpha/beta deficiency greatly exacerbates arthritogenic disease in mice infected with wild-type chikungunya virus but not with the cell culture-adapted live-attenuated 181/25 vaccine candidate.Q36200552
Genetic ablation of arginase 1 in macrophages and neutrophils enhances clearance of an arthritogenic alphavirusQ36303514
Mechanism of altered Sindbis virus neurovirulence associated with a single-amino-acid change in the E2 Glycoprotein.Q36682697
fus-1, a pH shift mutant of Semliki Forest virus, acts by altering spike subunit interactions via a mutation in the E2 subunitQ39578611
Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor.Q39580237
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectRoss River virusQ660537
P304page(s)5970-5984
P577publication date2013-03-20
P1433published inJournal of VirologyQ1251128
P1476titleA tyrosine-to-histidine switch at position 18 of the Ross River virus E2 glycoprotein is a determinant of virus fitness in disparate hosts
P478volume87

Reverse relations

cites work (P2860)
Q34810471CD8+ T cells control Ross River virus infection in musculoskeletal tissues of infected mice.
Q83227399Discrete viral E2 lysine residues and scavenger receptor MARCO are required for clearance of circulating alphaviruses
Q34391631Infection of myofibers contributes to increased pathogenicity during infection with an epidemic strain of chikungunya virus
Q47289858Inflammatory monocytes mediate control of acute alphavirus infection in mice.
Q90186745Localized Outbreaks of Epidemic Polyarthritis among Military Personnel Caused by Different Sublineages of Ross River Virus, Northeastern Australia, 2016-2017
Q28550385Loss of Glycosaminoglycan Receptor Binding after Mosquito Cell Passage Reduces Chikungunya Virus Infectivity
Q38659305MUTATIONS IN THE E2 GLYCOPROTEIN AND THE 3' UNTRANSLATED REGION ENHANCE CHIKUNGUNYA VIRUS VIRULENCE IN MICE.
Q35799153Myeloid Cell Arg1 Inhibits Control of Arthritogenic Alphavirus Infection by Suppressing Antiviral T Cells

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