Macrophage-induced adipose tissue dysfunction and the preadipocyte: should I stay (and differentiate) or should I go?

scientific article published on January 2013

Macrophage-induced adipose tissue dysfunction and the preadipocyte: should I stay (and differentiate) or should I go? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3945/AN.112.003020
P932PMC publication ID3648741
P698PubMed publication ID23319125

P50authorAnneMarie GagnonQ51113280
P2093author name stringAlexander Sorisky
André S D Molgat
P2860cites workInhibition of adipogenesis by Wnt signalingQ22254771
Regional differences in cellular mechanisms of adipose tissue gain with overfeedingQ24624643
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytesQ24681106
Historical perspectives in fat cell biology: the fat cell as a model for the investigation of hormonal and metabolic pathwaysQ27000360
Characterization of a human preadipocyte cell strain with high capacity for adipose differentiationQ28204416
Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitusQ28315009
Mitotic clonal expansion: a synchronous process required for adipogenesisQ28588756
Dynamics of fat cell turnover in humansQ29615688
Adipocytes as regulators of energy balance and glucose homeostasisQ29619448
Apoptosis of human abdominal preadipocytes before and after differentiation into adipocytes in culture.Q33188001
Adipocyte turnover: relevance to human adipose tissue morphologyQ33556451
Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytesQ33642552
A novel effect of growth hormone on macrophage modulates macrophage-dependent adipocyte differentiationQ33848254
Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosisQ34082884
Activin a plays a critical role in proliferation and differentiation of human adipose progenitorsQ34119609
The forkhead transcription factor Foxo1 regulates adipocyte differentiationQ34170890
Adipogenic potential of adipose stem cell subpopulations.Q34204172
The activation state of macrophages alters their ability to suppress preadipocyte apoptosis.Q34255795
Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA.Q34385931
A pericellular collagenase directs the 3-dimensional development of white adipose tissueQ34522343
Aging and regional differences in fat cell progenitors - a mini-reviewQ34540615
Developmental origin of fat: tracking obesity to its source.Q34705822
A decision between life and death during TNF-alpha-induced signalingQ34767059
Adipose tissue remodeling and obesityQ35015740
High-fat diet-induced adipocyte cell death occurs through a cyclophilin D intrinsic signaling pathway independent of adipose tissue inflammationQ35123520
Native human adipose stromal cells: localization, morphology and phenotypeQ35211725
Adipose tissue stem cells meet preadipocyte commitment: going back to the futureQ35715553
Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout miceQ35805369
Transcriptional control of adipocyte formationQ35962266
A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasisQ35981284
Intrinsic differences in adipocyte precursor cells from different white fat depots.Q36047557
Concise review: adipocyte origins: weighing the possibilitiesQ36190822
Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineageQ36448097
A family with severe insulin resistance and diabetes due to a mutation in AKT2.Q36481707
Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.Q37110569
BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineageQ37293278
Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.Q37376673
Alpha2-adrenergic receptor-mediated release of lysophosphatidic acid by adipocytes. A paracrine signal for preadipocyte growthQ37380211
The distinction of metabolically 'healthy' from 'unhealthy' obese individualsQ37633348
Defining macrophage phenotype and function in adipose tissueQ37880478
Forming functional fat: a growing understanding of adipocyte differentiationQ37939532
Immunity as a link between obesity and insulin resistanceQ37951148
Insulin-sensitive obesity in humans - a 'favorable fat' phenotype?Q37979422
The cellular and signaling networks linking the immune system and metabolism in diseaseQ37991199
A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alphaQ38321742
The fat cellQ38597703
Differential function of Akt1 and Akt2 in human adipocytesQ39368718
The anti-adipogenic effect of macrophage-conditioned medium requires the IKKβ/NF-κB pathway.Q39661936
Macrophage-conditioned medium inhibits differentiation-induced Rb phosphorylation in 3T3-L1 preadipocytesQ39913441
Control of adipocyte differentiationQ40462294
Expression and regulation of neuronal apoptosis inhibitory protein during adipocyte differentiationQ40991230
Regulation and expression of retinoblastoma proteins p107 and p130 during 3T3-L1 adipocyte differentiationQ41116315
White fat progenitor cells reside in the adipose vasculature.Q41145314
Cycloheximide-induced modulation of TNF-mediated cytotoxicity in sensitive and resistant ovarian tumor cellsQ41749690
IGF-I inhibits apoptosis induced by serum withdrawal, but potentiates TNF-alpha-induced apoptosis, in 3T3-L1 preadipocytes.Q42494171
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.Q42511063
Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species.Q42797861
Preadipocyte apoptosis is prevented by macrophage-conditioned medium in a PDGF-dependent manner.Q42803013
Macrophage-conditioned medium inhibits the differentiation of 3T3-L1 and human abdominal preadipocytesQ42803452
The mechanism of inhibition of 3T3-L1 preadipocyte differentiation by prostaglandin F2alphaQ42806720
Catalytically inactive SHIP2 inhibits proliferation by attenuating PDGF signaling in 3T3-L1 preadipocytes.Q42808112
Macrophage-conditioned medium inhibits the activation of cyclin-dependent kinase 2 by adipogenic inducers in 3T3-L1 preadipocytesQ42809621
Expression of a constitutively activated form of protein kinase B (c-Akt) in 3T3-L1 preadipose cells causes spontaneous differentiationQ42810650
Adipose tissue macrophages inhibit adipogenesis of mesenchymal precursor cells via wnt-5a in humansQ42815164
The antiadipogenic effect of macrophage-conditioned medium depends on ERK1/2 activationQ42815864
Macrophage-induced preadipocyte survival depends on signaling through Akt, ERK1/2, and reactive oxygen species.Q42818553
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytesQ42820082
Protein kinase B/AKT 1 plays a pivotal role in insulin-like growth factor-1 receptor signaling induced 3T3-L1 adipocyte differentiationQ42828148
Alpha 2-adrenergic stimulation promotes preadipocyte proliferation. Involvement of mitogen-activated protein kinases.Q42831985
Phosphatidylinositol-3,4,5-trisphosphate is required for insulin-like growth factor 1-mediated survival of 3T3-L1 preadipocytesQ42832853
Interleukin-4 inhibits platelet-derived growth factor-induced preadipocyte proliferationQ42832942
Human adipose tissue endothelial cells promote preadipocyte proliferationQ43762958
Adipose tissue triglyceride turnover, de novo lipogenesis, and cell proliferation in humans measured with2H2OQ44643865
Inhibition of death-receptor mediated apoptosis in human adipocytes by the insulin-like growth factor I (IGF-I)/IGF-I receptor autocrine circuitQ44703136
Comparison of proliferation and differentiation capacity of human adipocyte precursor cells from the omental and subcutaneous adipose tissue depot of obese subjectsQ44887109
Macrophages alter the differentiation-dependent decreases in fibronectin and collagen I/III protein levels in human preadipocytes.Q47389960
Evidence of in situ proliferation of adult adipose tissue-derived progenitor cells: influence of fat mass microenvironment and growthQ47413995
Human preadipocytes display a depot-specific susceptibility to apoptosisQ47690632
Subcutaneous abdominal preadipocyte differentiation in vitro inversely correlates with central obesity.Q51032064
Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes.Q51109464
Downregulation of FLIP by cycloheximide sensitizes human fat cells to CD95-induced apoptosis.Q51370749
An established pre-adipose cell line and its differentiation in culture.Q52826449
Stimulation of inflammatory gene expression in human preadipocytes by macrophage-conditioned medium: upregulation of IL-6 production by macrophage-derived IL-1β.Q54339599
The subcutaneous adipose tissue reservoir of functionally active stem cells is reduced in obese patientsQ59255837
Characterization of human adipose-derived stem cells.Q64984073
Relationship between replication and differentiation in cultured human adipocyte precursor cellsQ71800347
Paracrine stimulation of preadipocyte-enriched cell cultures by mature adipocytesQ71897766
Tumor necrosis factor-alpha induces apoptosis of human adipose cellsQ73929085
Failure of adipocyte differentiation causes type II diabetes mellitus?Q74268310
The effect of adipocyte differentiation on the capacity of 3T3-L1 cells to undergo apoptosis in response to growth factor deprivationQ74780905
Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1Q76360079
Effects of thyrotropin on the proliferation and differentiation of cultured rat preadipocytesQ78015092
Committed subcutaneous preadipocytes are reduced in human obesityQ79345667
Primary culture and differentiation of human adipocyte precursor cellsQ80879520
Identification of white adipocyte progenitor cells in vivoQ82206003
Primary culture of human adipocyte precursor cells: expansion and differentiationQ82369393
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)67-75
P577publication date2013-01-01
P1433published inAdvances in NutritionQ20821073
P1476titleMacrophage-induced adipose tissue dysfunction and the preadipocyte: should I stay (and differentiate) or should I go?
P478volume4

Reverse relations

cites work (P2860)
Q614437051α,25(OH)D attenuates IL-6 and IL-1β-mediated inflammatory responses in macrophage conditioned medium-stimulated human white preadipocytes by modulating p44/42 MAPK and NF-κB signaling pathways
Q39094912Activated macrophages as key mediators of capsule formation on adipose constructs in tissue engineering chamber models
Q36996047Anti-Inflammatory Effect of Spirulina platensis in Macrophages Is Beneficial for Adipocyte Differentiation and Maturation by Inhibiting Nuclear Factor-κB Pathway in 3T3-L1 Adipocytes
Q37566857Characterization of adipose tissue macrophages and adipose-derived stem cells in critical wounds.
Q30592402Characterization of immune cells in psoriatic adipose tissue
Q89529434Effects of 1,25-dihydroxyvitamin D3 on the Inflammatory Responses of Stromal Vascular Cells and Adipocytes from Lean and Obese Mice
Q51733866Groundsel Bush (Baccharis halimifolia) Extract Promotes Adipocyte Differentiation In Vitro and Increases Adiponectin Expression in Mature Adipocytes.
Q38235141Inflammation and macrophage modulation in adipose tissues.
Q36412774Macrophage functions in lean and obese adipose tissue
Q51138789Macrophages Undergo M1-to-M2 Transition in Adipose Tissue Regeneration in a Rat Tissue Engineering Model.
Q36446306Mice subjected to aP2-Cre mediated ablation of microsomal triglyceride transfer protein are resistant to high fat diet induced obesity
Q47118766Natural product celastrol suppressed macrophage M1 polarization against inflammation in diet-induced obese mice via regulating Nrf2/HO-1, MAP kinase and NF-κB pathways.
Q36210329Neuroendocrine Inflammatory Responses in Overweight/Obese Infants
Q35834755Pathways commonly dysregulated in mouse and human obese adipose tissue: FAT/CD36 modulates differentiation and lipogenesis
Q38699786Physiological and pathological impact of exosomes of adipose tissue
Q30234642Prokineticin Is a New Linker between Obesity and Cardiovascular Diseases
Q37700389Sleep fragmentation in mice induces nicotinamide adenine dinucleotide phosphate oxidase 2-dependent mobilization, proliferation, and differentiation of adipocyte progenitors in visceral white adipose tissue
Q36466672Study on inflammation-related genes and microRNAs, with special emphasis on the vascular repair factor HGF and miR-574-3p, in monocytes and serum of patients with T2D.
Q91105838The Effect of Early Rounds of ex vivo Expansion and Cryopreservation on the Adipogenic Differentiation Capacity of Adipose-Derived Stromal/Stem Cells
Q51113223The anti-adipogenic effect of peripheral blood mononuclear cells is absent with PCSK9 loss-of-function variants.
Q26751365Thyroid Hormones, Oxidative Stress, and Inflammation
Q35665925Type 2 Diabetes Monocyte MicroRNA and mRNA Expression: Dyslipidemia Associates with Increased Differentiation-Related Genes but Not Inflammatory Activation
Q91286750iTRAQ-Based Quantitative Proteomic Comparison of 2D and 3D Adipocyte Cell Models Co-cultured with Macrophages Using Online 2D-nanoLC-ESI-MS/MS

Search more.