Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage

scholarly article

Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2004PNAS..101.9607T
P356DOI10.1073/PNAS.0403100101
P932PMC publication ID470722
P698PubMed publication ID15210946
P5875ResearchGate publication ID8497175

P2093author name stringTamara C Otto
M Daniel Lane
Qi-Qun Tang
P2860cites workInhibition of adipogenesis by Wnt signalingQ22254771
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytesQ24681106
Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteinsQ28287408
Mitotic clonal expansion: a synchronous process required for adipogenesisQ28588756
The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinaseQ28628494
Expression of a single transfected cDNA converts fibroblasts to myoblastsQ29547764
Mesenchymal stem cellsQ29619804
10T1/2 cells: an in vitro model for molecular genetic analysis of mesodermal determination and differentiationQ30445896
Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of divisionQ34207595
Formation of normally differentiated subcutaneous fat pads by an established preadipose cell lineQ34233127
Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.Q34285754
Transcriptional regulation of gene expression during adipocyte differentiationQ34296723
Regulation of adipocyte developmentQ34324691
Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissueQ34343775
An established preadipose cell line and its differentiation in culture II. Factors affecting the adipose conversionQ34509691
Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiationQ35205402
The mesengenic processQ40631427
Regulating adipogenesisQ41431329
Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineagesQ41510547
Mitotic clonal expansion during preadipocyte differentiation: calpain-mediated turnover of p27.Q42803586
An established pre-adipose cell line and its differentiation in cultureQ52826449
Adipose tissue cellularity in human obesityQ66886876
Mesenchymal stem cells reside within the connective tissues of many organsQ72202802
Preadipocyte recruitment in stromal vascular cultures after depletion of committed preadipocytes by immunocytotoxicityQ73134694
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectadipocyteQ357519
pluripotencyQ1894941
P1104number of pages5
P304page(s)9607-9611
P577publication date2004-06-21
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleCommitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
P478volume101

Reverse relations

cites work (P2860)
Q37208047A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance.
Q90465698A Lox/CHOP-10 crosstalk governs osteogenic and adipogenic cell fate by MSCs
Q37769112A chromatin perspective of adipogenesis.
Q37413328A review of stem cell translation and potential confounds by cancer stem cells.
Q37110943A role for phosphodiesterase 3B in acquisition of brown fat characteristics by white adipose tissue in male mice.
Q29615690Adipocyte differentiation from the inside out
Q26828614Adipogenesis
Q37998565Adipogenesis: From Stem Cell to Adipocyte
Q36304460Adipose tissue Mest and Sfrp5 are concomitant with variations of adiposity among inbred mouse strains fed a non-obesogenic diet
Q38154504Adipose tissue browning and metabolic health
Q37317464Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity
Q35715553Adipose tissue stem cells meet preadipocyte commitment: going back to the future
Q34371949Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-gamma2 transcription factor and TGF-beta/BMP signaling pathways
Q47097132Alterations of protein glycosylation in embryonic stem cells during adipogenesis
Q90409945Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome
Q28854368Amplification of Adipogenic Commitment by VSTM2A
Q42833567An essential role for Ewing sarcoma gene (EWS) in early white adipogenesis
Q39439179Apert syndrome mutant FGFR2 and its soluble form reciprocally alter osteogenesis of primary calvarial osteoblasts
Q41637054Artemisinin derivatives prevent obesity by inducing browning of WAT and enhancing BAT function
Q42181656Association of genetic variants of BMP4 with type 2 diabetes mellitus and clinical traits in a Chinese Han population
Q38602968BBS4 regulates the expression and secretion of FSTL1, a protein that participates in ciliogenesis and the differentiation of 3T3-L1.
Q37293278BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
Q33917485BMP-TAK1 (MAP3K7) Induces Adipocyte Differentiation Through PPARγ Signaling
Q43911045BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells
Q55026068BMP4 mediates the interplay between adipogenesis and angiogenesis during expansion of subcutaneous white adipose tissue.
Q36653911BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis
Q24321265BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions
Q47103852BMP9 induces osteogenesis and adipogenesis in the immortalized human cranial suture progenitors from the patent sutures of craniosynostosis patients
Q26824827BMPs and their clinical potentials
Q60961761Beyond the bone: Bone morphogenetic protein signaling in adipose tissue
Q41885469Bisphenol A increases aP2 expression in 3T3L1 by enhancing the transcriptional activity of nuclear receptors at the promoter
Q39116293Bmp4 expressed in preadipocytes is required for the onset of adipocyte differentiation
Q39497817Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots
Q91932763Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes
Q35913048Bone morphogenetic protein 7 (BMP7) reverses obesity and regulates appetite through a central mTOR pathway
Q37293132Bone morphogenetic protein 9 (BMP9) induces effective bone formation from reversibly immortalized multipotent adipose-derived (iMAD) mesenchymal stem cells
Q38117395Brown adipose tissue: development, metabolism and beyond
Q38312239Brown and beige fat: the metabolic function, induction, and therapeutic potential
Q24544140CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells
Q38110443Cell transplantation therapy for diabetes mellitus: endocrine pancreas and adipocyte [Review]
Q34513293Cells derived from murine induced pluripotent stem cells (iPSC) by treatment with members of TGF-beta family give rise to osteoblasts differentiation and form bone in vivo.
Q38300332Characterization of ScAP-23, a new cell line from murine subcutaneous adipose tissue, identifies genes for the molecular definition of preadipocytes
Q43077735Characterization of the adipocyte cellular lineage in vivo
Q36916637Chromatin and chromatin-modifying proteins in adipogenesis.
Q38552228Could burning fat start with a brite spark? Pharmacological and nutritional ways to promote thermogenesis
Q64060804Current Research Approaches and Challenges in the Obesogen Field
Q38758497Defining human insulin-like growth factor I gene regulation
Q37848703Developmental origins of the adipocyte lineage: new insights from genetics and genomics studies.
Q34546872Distinct adipogenic differentiation phenotypes of human umbilical cord mesenchymal cells dependent on adipogenic conditions.
Q39907392Downregulated expression of the secreted glycoprotein follistatin-like 1 (Fstl1) is a robust hallmark of preadipocyte to adipocyte conversion
Q50130176Downregulation of β1,4-galactosyltransferase 5 improves insulin resistance by promoting adipocyte commitment and reducing inflammation.
Q36515904Dual functions of TAF7L in adipocyte differentiation
Q41846656Dual-stage growth factor release within 3D protein-engineered hydrogel niches promotes adipogenesis
Q35894025Effect of Diabetes Mellitus on Adipocyte-Derived Stem Cells in Rat
Q98164843Effect of microenvironment on adhesion and differentiation of murine C3H10T1/2 cells cultured on multilayers containing collagen I and glycosaminoglycans
Q47976856Effects of bone morphogenetic protein-4 (BMP-4) on adipocyte differentiation from mouse adipose-derived stem cells.
Q39747803Effects of cartilage-derived morphogenetic protein-3 on the expression of chondrogenic and osteoblastic markers in the pluripotent mesenchymal C3H10T1/2 cell line
Q35281711Effects of culture on PAMPS/PDMAAm double-network gel on chondrogenic differentiation of mouse C3H10T1/2 cells: in vitro experimental study
Q46959630Elucidating the Preadipocyte and Its Role in Adipocyte Formation: a Comprehensive Review
Q24652412Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism
Q36003155Emerging roles for the transforming growth factor-{beta} superfamily in regulating adiposity and energy expenditure
Q28307782Endocrine disrupting chemicals and the developmental programming of adipogenesis and obesity
Q64241149Endocrine-Mediated Mechanisms of Metabolic Disruption and New Approaches to Examine the Public Health Threat
Q38187493Endogenous ways to stimulate brown adipose tissue in humans
Q53449208Enhanced adipogenic differentiation and reduced collagen synthesis induced by human periodontal ligament stem cells might underlie the negative effect of recombinant human bone morphogenetic protein-2 on periodontal regeneration.
Q42795840Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity.
Q26766574Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
Q38151178Feeding the heat on brown fat.
Q34393763G0/G1 switch gene 2 has a critical role in adipocyte differentiation.
Q42824339G9a is transactivated by C/EBPβ to facilitate mitotic clonal expansion during 3T3-L1 preadipocyte differentiation
Q39176003Gdf6 induces commitment of pluripotent mesenchymal C3H10T1/2 cells to the adipocyte lineage
Q62017019HDAC3-Selective Inhibition Activates Brown and Beige Fat Through PRDM16
Q27000360Historical perspectives in fat cell biology: the fat cell as a model for the investigation of hormonal and metabolic pathways
Q34298015ISL1 regulates peroxisome proliferator-activated receptor γ activation and early adipogenesis via bone morphogenetic protein 4-dependent and -independent mechanisms.
Q35612446Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors
Q34472039Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat.
Q35176549Identification of the transcription factor ZEB1 as a central component of the adipogenic gene regulatory network
Q37058147Identification of zinc finger protein Bcl6 as a novel regulator of early adipose commitment
Q37665422Improved methodologies for the study of adipose biology: insights gained and opportunities ahead
Q38724549In Vitro and in Vivo Analyses Reveal Profound Effects of Fibroblast Growth Factor 16 as a Metabolic Regulator
Q39673628Indomethacin promotes adipogenesis of mesenchymal stem cells through a cyclooxygenase independent mechanism
Q39783162Inhibitory effect of evodiamine alone and in combination with rosiglitazone on in vitro adipocyte differentiation and in vivo obesity related to diabetes
Q37808266Integrative physiology of the aging bone: insights from animal and cellular models
Q34454920Involvement of cytoskeleton-associated proteins in the commitment of C3H10T1/2 pluripotent stem cells to adipocyte lineage induced by BMP2/4
Q47101513Lack of Adipocyte-Fndc5/Irisin Expression and Secretion Reduces Thermogenesis and Enhances Adipogenesis
Q38810222Lsd1 prevents age-programed loss of beige adipocytes
Q36828792Macrophage-induced adipose tissue dysfunction and the preadipocyte: should I stay (and differentiate) or should I go?
Q39529568Mediator MED23 links insulin signaling to the adipogenesis transcription cascade
Q48166426Mesenchymal Stem Cells: Cell Fate Decision to Osteoblast or Adipocyte and Application in Osteoporosis Treatment
Q38729746Mesenchymal stem cells in obesity: insights for translational applications
Q37060793MiR-503 inhibits adipogenesis by targeting bone morphogenetic protein receptor 1a.
Q36708530MicroRNA-140 Promotes Adipocyte Lineage Commitment of C3H10T1/2 Pluripotent Stem Cells via Targeting Osteopetrosis-associated Transmembrane Protein 1
Q37210859Mitochondrial dysfunction in obesity
Q98735917Molecular Mechanism of Stem Cell Differentiation into Adipocytes and Adipocyte Differentiation of Malignant Tumor
Q26770105Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules
Q38241502Molecular pathways regulating the formation of brown-like adipocytes in white adipose tissue
Q43215836Myocardin-related transcription factor A regulates conversion of progenitors to beige adipocytes
Q35070319Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects
Q37879255Myostatin: A novel insight into its role in metabolism, signal pathways, and expression regulation
Q24652521New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
Q38686350Non-viral approaches for direct conversion into mesenchymal cell types: Potential application in tissue engineering
Q42107342Nuclear localization of DMP1 proteins suggests a role in intracellular signaling
Q35806814Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak-/- Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure
Q40119662Osteogenic and adipogenic potential of porcine adipose mesenchymal stem cells
Q47711942Osteogenic potential of adipogenic predifferentiated human bone marrow-derived multipotent stromal cells for bone tissue-engineering
Q26864900Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy
Q41991392Oxidative stress induces imbalance of adipogenic/osteoblastic lineage commitment in mesenchymal stem cells through decreasing SIRT1 functions
Q41871002PPARγ ligand production is tightly linked to clonal expansion during initiation of adipocyte differentiation
Q33965312Post-transcriptional regulation in osteoblasts using localized delivery of miR-29a inhibitor from nanofibers to enhance extracellular matrix deposition
Q38390268Prmt7 is dispensable in tissue culture models for adipogenic differentiation
Q38708579Probe-Dependent Negative Allosteric Modulators of the Long-Chain Free Fatty Acid Receptor FFA4.
Q38202879Redox mechanisms in regulation of adipocyte differentiation: beyond a general stress response
Q37220951Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue
Q39537935Retinoic acid inhibits BMP4-induced C3H10T1/2 stem cell commitment to adipocyte via downregulating Smad/p38MAPK signaling
Q47676663Retinoic acid inhibits white adipogenesis by disrupting GADD45A-mediated Zfp423 DNA demethylation.
Q46134215Retinoid X Receptor Activation Alters the Chromatin Landscape To Commit Mesenchymal Stem Cells to the Adipose Lineage.
Q38177814Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation.
Q28085224Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism
Q35536339RhoGDIβ Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation
Q39042452Role of bone morphogenetic protein 4 in the differentiation of brown fat-like adipocytes
Q47130478SCARA5 plays a critical role in the commitment of mesenchymal stem cells to adipogenesis
Q37718426SIRT1 suppresses adipogenesis by activating Wnt/β-catenin signaling in vivo and in vitro
Q47327411Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes.
Q92705326Senile Osteoporosis: The Involvement of Differentiation and Senescence of Bone Marrow Stromal Cells
Q37164220Shp2 suppresses the adipogenic differentiation of preadipocyte 3T3-L1 cells at an early stage
Q36342092Smad8/BMP2‐engineered mesenchymal stem cells induce accelerated recovery of the biomechanical properties of the achilles tendon
Q38935993Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte
Q38754121Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells
Q35016478Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: role of the BMP-4 gene.
Q36647686TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator
Q39308262TGF-β Family Signaling in Mesenchymal Differentiation
Q93036211TGF-β/SMAD signaling regulation of mesenchymal stem cells in adipocyte commitment
Q28473419Tgf-Beta inhibition restores terminal osteoblast differentiation to suppress myeloma growth
Q41849781The Novel Secreted Adipokine WNT1-inducible Signaling Pathway Protein 2 (WISP2) Is a Mesenchymal Cell Activator of Canonical WNT.
Q35902839The WNT Inhibitor Dickkopf 1 and Bone Morphogenetic Protein 4 Rescue Adipogenesis in Hypertrophic Obesity in Humans
Q33521230The ZEB1 transcription factor is a novel repressor of adiposity in female mice
Q39460852The actin-binding domain of actin filament-associated protein (AFAP) is involved in the regulation of cytoskeletal structure
Q46142386The activin-βA/BMP-2 chimera AB204 is a strong stimulator of adipogenesis
Q47326297The dual role of BMP4 in adipogenesis and metabolism
Q42809852The forkhead transcription factor FOXO1 stimulates the expression of the adipocyte resistin gene.
Q38608775The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma
Q37369119The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation
Q31120243The immunoglobulin superfamily protein differentiation of embryonic stem cells 1 (dies1) has a regulatory role in preadipocyte to adipocyte conversion
Q42709950The miR-181d-regulated metalloproteinase Adamts1 enzymatically impairs adipogenesis via ECM remodeling
Q89022203The potential of brown adipogenesis and browning in porcine bone marrow-derived mesenchymal stem cells1
Q90374946The regulatory protein SnoN antagonizes activin/Smad2 protein signaling and thereby promotes adipocyte differentiation and obesity in mice
Q31118490The role of paracrine and autocrine signaling in the early phase of adipogenic differentiation of adipose-derived stem cells
Q87840724Three-dimensional spheroid culture of adipose stromal vascular cells for studying adipogenesis in beef cattle
Q38947016Thyroid hormone acting via TRβ induces expression of browning genes in mouse bone marrow adipose tissue.
Q37429465Transcriptional control of brown adipocyte development and physiological function--of mice and men.
Q33753951Transcriptional control of preadipocyte determination by Zfp423.
Q92239529Up-regulation of bone morphogenetic protein and its signaling molecules following castration of bulls and their association with intramuscular fat content in Korean cattle
Q33678794Utility of transplantation in studying adipocyte biogenesis and function
Q90663628Vesicles Shed by Pathological Murine Adipocytes Spread Pathology: Characterization and Functional Role of Insulin Resistant/Hypertrophied Adiposomes
Q48301972Visceral and subcutaneous adipose tissue express and secrete functional alpha2hsglycoprotein (fetuin a) especially in obesity
Q92257387Vulpinic Acid Controls Stem Cell Fate toward Osteogenesis and Adipogenesis
Q36616934WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.
Q48603044WITHDRAWN: Modulation of adipocyte function by the TGF-β family
Q47624355miR-27 impairs the adipogenic lineage commitment via targeting lysyl oxidase
Q38090591microRNAs regulate adipocyte differentiation
Q47927399p107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells
Q57161298p53 Functions in Adipose Tissue Metabolism and Homeostasis

Search more.