Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: role of the BMP-4 gene.

scholarly article

Stable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: role of the BMP-4 gene. is …
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scholarly articleQ13442814

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P819ADS bibcode2006PNAS..10313022B
P356DOI10.1073/PNAS.0605789103
P932PMC publication ID1559746
P698PubMed publication ID16916928
P5875ResearchGate publication ID6871023

P50authorJae-Woo KimQ62566487
P2093author name stringTamara C Otto
M Daniel Lane
Robert R Bowers
P2860cites workBMP-binding modules in chordin: a model for signalling regulation in the extracellular spaceQ24646285
The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signallingQ24656491
Obese gene expression at in vivo levels by fat pads derived from s.c. implanted 3T3-F442A preadipocytesQ24681106
HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteinsQ28245903
Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiationQ28269495
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesisQ28506504
Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiationQ28513083
A novel secretory factor, Neurogenesin-1, provides neurogenic environmental cues for neural stem cells in the adult hippocampusQ28568364
Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblastsQ28588627
Mitotic clonal expansion: a synchronous process required for adipogenesisQ28588756
Expression of a single transfected cDNA converts fibroblasts to myoblastsQ29547764
10T1/2 cells: an in vitro model for molecular genetic analysis of mesodermal determination and differentiationQ30445896
Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscleQ34078570
Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of divisionQ34207595
Analysis of gene expression during differentiation of adipogenic cells in culture and hormonal control of the developmental programQ34258600
Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes.Q34285754
Transcriptional regulation of gene expression during adipocyte differentiationQ34296723
CCAAT/enhancer-binding protein beta is required for mitotic clonal expansion during adipogenesisQ34327828
Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissueQ34343775
Multiple new phenotypes induced in and 3T3 cells treated with 5-azacytidineQ34418477
Spontaneous heritable changes leading to increased adipose conversion in 3T3 cellsQ34459851
Epiblast cells that express MyoD recruit pluripotent cells to the skeletal muscle lineageQ35098785
Activation and centromeric localization of CCAAT/enhancer-binding proteins during the mitotic clonal expansion of adipocyte differentiationQ35205402
Adipose development: from stem cell to adipocyteQ36242589
Differential Roles for Bone Morphogenetic Protein (BMP) Receptor Type IB and IA in Differentiation and Specification of Mesenchymal Precursor Cells to Osteoblast and Adipocyte LineagesQ36256208
Commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineageQ36448097
The mouse bone morphogenetic protein-4 gene. Analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP-TFI orphan receptorQ36672672
Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosidesQ39548154
Retinoic acid repression of bone morphogenetic protein 4 in inner ear developmentQ39737111
Extracellular matrix-associated bone morphogenetic proteins are essential for differentiation of murine osteoblastic cells in vitroQ40958301
Use of monoclonal antibody to detect bone morphogenetic protein-4 (BMP-4).Q41394644
Expression of human bone morphogenetic proteins-2 or -4 in murine mesenchymal progenitor C3H10T1/2 cells induces differentiation into distinct mesenchymal cell lineagesQ41510547
Modulating the transcriptional control of adipogenesisQ41655698
Proteolytic cleavage of Chordin as a switch for the dual activities of Twisted gastrulation in BMP signalingQ41835575
Commitment of mouse fibroblasts to adipocyte differentiation by DNA transfectionQ42798371
Understanding Adipocyte DifferentiationQ46119331
MSX2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors.Q54759836
5-azacytidine induction of stable mesodermal stem cell lineages from 10T1/2 cells: Evidence for regulatory genes controlling determinationQ72747497
P433issue35
P407language of work or nameEnglishQ1860
P921main subjectadipocyteQ357519
DNA methylationQ874745
P304page(s)13022-13027
P577publication date2006-08-17
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleStable stem cell commitment to the adipocyte lineage by inhibition of DNA methylation: role of the BMP-4 gene
P478volume103

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cites work (P2860)
Q37208047A Functional Link between AMPK and Orexin Mediates the Effect of BMP8B on Energy Balance.
Q90465698A Lox/CHOP-10 crosstalk governs osteogenic and adipogenic cell fate by MSCs
Q37769112A chromatin perspective of adipogenesis.
Q35095530A comprehensive analysis of the dual roles of BMPs in regulating adipogenic and osteogenic differentiation of mesenchymal progenitor cells
Q35834361A1 adenosine receptors play an essential role in protecting the embryo against hypoxia
Q90893796Adipogenesis and metabolic health
Q37998565Adipogenesis: From Stem Cell to Adipocyte
Q38809397Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids
Q35715553Adipose tissue stem cells meet preadipocyte commitment: going back to the future
Q42814976Ahnak stimulates BMP2-mediated adipocyte differentiation through Smad1 activation
Q88651938Alteration of Bone Mineral Density Differs Between Genders in Obese Subjects After Laparoscopic Sleeve Gastrectomy: Bone Morphogenetic Protein 4 May Count
Q47097132Alterations of protein glycosylation in embryonic stem cells during adipogenesis
Q28854368Amplification of Adipogenic Commitment by VSTM2A
Q37634014Androgens inhibit adipogenesis during human adipose stem cell commitment to preadipocyte formation.
Q40675675Anti-inflammatory properties of bone morphogenetic protein 4 in human adipocytes
Q42181656Association of genetic variants of BMP4 with type 2 diabetes mellitus and clinical traits in a Chinese Han population
Q38602968BBS4 regulates the expression and secretion of FSTL1, a protein that participates in ciliogenesis and the differentiation of 3T3-L1.
Q37293278BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage
Q43911045BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells
Q36653911BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis
Q26824827BMPs and their clinical potentials
Q47141298BMPs as new insulin sensitizers: enhanced glucose uptake in mature 3T3-L1 adipocytes via PPARγ and GLUT4 upregulation.
Q60961761Beyond the bone: Bone morphogenetic protein signaling in adipose tissue
Q39116293Bmp4 expressed in preadipocytes is required for the onset of adipocyte differentiation
Q39497817Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots
Q38312239Brown and beige fat: the metabolic function, induction, and therapeutic potential
Q47244341CCN5/WISP2 and metabolic diseases
Q30431234Cell density-dependent transcriptional activation of endocrine-related genes in human adipose tissue-derived stem cells
Q38110443Cell transplantation therapy for diabetes mellitus: endocrine pancreas and adipocyte [Review]
Q36916637Chromatin and chromatin-modifying proteins in adipogenesis.
Q43223388Corticosteroid-induced kidney dysmorphogenesis is associated with deregulated expression of known cystogenic molecules, as well as Indian hedgehog
Q41881060Cross talk between insulin and bone morphogenetic protein signaling systems in brown adipogenesis.
Q37428130Cultured Human Periosteum-Derived Cells Can Differentiate into Osteoblasts in a Perioxisome Proliferator-Activated Receptor Gamma-Mediated Fashion via Bone Morphogenetic Protein signaling
Q91742313DNA methylation of the PLIN1 promoter downregulates expression in chicken lines
Q34700590Defective osteogenic differentiation in the development of osteosarcoma
Q39444896Depolarization alters phenotype, maintains plasticity of pre-differentiated mesenchymal stem cells
Q39407102Depolarization alters phenotype, maintains plasticity of predifferentiated mesenchymal stem cells
Q38469502Differential lncRNA expression profiles in brown and white adipose tissues
Q34546872Distinct adipogenic differentiation phenotypes of human umbilical cord mesenchymal cells dependent on adipogenic conditions.
Q39907392Downregulated expression of the secreted glycoprotein follistatin-like 1 (Fstl1) is a robust hallmark of preadipocyte to adipocyte conversion
Q33286093Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence
Q47976856Effects of bone morphogenetic protein-4 (BMP-4) on adipocyte differentiation from mouse adipose-derived stem cells.
Q36003155Emerging roles for the transforming growth factor-{beta} superfamily in regulating adiposity and energy expenditure
Q42453666Epigallocatechin Gallate Inhibits Mouse Mesenchymal Stem Cell Differentiation to Adipogenic Lineage
Q37147061Epigenetic DNA Demethylation Causes Inner Ear Stem Cell Differentiation into Hair Cell-Like Cells
Q50747352Epigenetic DNA methylation in the promoters of peroxisome proliferator-activated receptor γ in chicken lines divergently selected for fatness
Q42823354Epigenetic Priming Confers Direct Cell Trans-Differentiation From Adipocyte to Osteoblast in a Transgene-Free State.
Q42795840Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity.
Q34176762Epigenetic regulation of adipocyte differentiation and adipogenesis
Q89140841Epigenomic Control of Thermogenic Adipocyte Differentiation and Function
Q58699530Essential role of Ahnak in adipocyte differentiation leading to the transcriptional regulation of Bmpr1α expression
Q33785831Essential role of BMPs in FGF-induced secondary lens fiber differentiation.
Q36709678FTO, obesity and the adolescent brain
Q90212918Functional Implications of DNA Methylation in Adipose Biology
Q33524582Gene expression profiles in Atlantic salmon adipose-derived stromo-vascular fraction during differentiation into adipocytes
Q46678841Genetic influence on dysmorphogenesis in embryos from different rat strains exposed to ethanol in vivo and in vitro
Q27000360Historical perspectives in fat cell biology: the fat cell as a model for the investigation of hormonal and metabolic pathways
Q35612446Identification of BMP and activin membrane-bound inhibitor (BAMBI) as a potent negative regulator of adipogenesis and modulator of autocrine/paracrine adipogenic factors
Q37872602In vitro Differentiation Potential of Mesenchymal Stem Cells
Q39673628Indomethacin promotes adipogenesis of mesenchymal stem cells through a cyclooxygenase independent mechanism
Q36860037Inhibiting DNA methylation switches adipogenesis to osteoblastogenesis by activating Wnt10a
Q39783162Inhibitory effect of evodiamine alone and in combination with rosiglitazone on in vitro adipocyte differentiation and in vivo obesity related to diabetes
Q36047557Intrinsic differences in adipocyte precursor cells from different white fat depots.
Q34454920Involvement of cytoskeleton-associated proteins in the commitment of C3H10T1/2 pluripotent stem cells to adipocyte lineage induced by BMP2/4
Q42912088Matrix remodeling as stem cell recruitment event: A novel in vitro model for homing of human bone marrow stromal cells to the site of injury shows crucial role of extracellular collagen matrix
Q39408383Mechanical stretch suppresses BMP4 induction of stem cell adipogenesis via upregulating ERK but not through downregulating Smad or p38
Q26745520Mesenchymal Stem Cells and Metabolic Syndrome: Current Understanding and Potential Clinical Implications
Q37060793MiR-503 inhibits adipogenesis by targeting bone morphogenetic protein receptor 1a.
Q37210859Mitochondrial dysfunction in obesity
Q37962744Molecular Mediators of Mesenchymal Stem Cell Biology
Q38588243Molecular basis of differentiation therapy for soft tissue sarcomas
Q37736639New association of bone morphogenetic protein 4 concentrations with fat distribution in obesity and Exenatide intervention on it.
Q40971428Noggin inactivation affects the number and differentiation potential of muscle progenitor cells in vivo.
Q34712757Notch signaling pathway activation in normal and hyperglycemic rats differs in the stem cells of visceral and subcutaneous adipose tissue
Q26746261Nutrigenomics and Beef Quality: A Review about Lipogenesis
Q35806814Obesity Resistance and Enhanced Insulin Sensitivity in Ahnak-/- Mice Fed a High Fat Diet Are Related to Impaired Adipogenesis and Increased Energy Expenditure
Q38558581Opportunities and challenges in three-dimensional brown adipogenesis of stem cells
Q37668148Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance
Q35676240Pref-1 (preadipocyte factor 1) activates the MEK/extracellular signal-regulated kinase pathway to inhibit adipocyte differentiation
Q92948023Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells
Q26859278Regulation of Adipocyte Differentiation via MicroRNAs
Q41177139Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation
Q37110526Restricted adipogenesis in hypertrophic obesity: the role of WISP2, WNT, and BMP4
Q39537935Retinoic acid inhibits BMP4-induced C3H10T1/2 stem cell commitment to adipocyte via downregulating Smad/p38MAPK signaling
Q46134215Retinoid X Receptor Activation Alters the Chromatin Landscape To Commit Mesenchymal Stem Cells to the Adipose Lineage.
Q38177814Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation.
Q39042452Role of bone morphogenetic protein 4 in the differentiation of brown fat-like adipocytes
Q47130478SCARA5 plays a critical role in the commitment of mesenchymal stem cells to adipogenesis
Q92705326Senile Osteoporosis: The Involvement of Differentiation and Senescence of Bone Marrow Stromal Cells
Q30492259Spontaneously beating cardiomyocytes derived from white mature adipocytes.
Q39308262TGF-β Family Signaling in Mesenchymal Differentiation
Q93036211TGF-β/SMAD signaling regulation of mesenchymal stem cells in adipocyte commitment
Q90722241The Beige Adipocyte as a Therapy for Metabolic Diseases
Q28078585The Bone Marrow-Derived Stromal Cells: Commitment and Regulation of Adipogenesis
Q35902839The WNT Inhibitor Dickkopf 1 and Bone Morphogenetic Protein 4 Rescue Adipogenesis in Hypertrophic Obesity in Humans
Q47326297The dual role of BMP4 in adipogenesis and metabolism
Q44564224The role of focal adhesion kinase in BMP4 induction of mesenchymal stem cell adipogenesis
Q33674615Therapeutic Implications of PPARgamma in Human Osteosarcoma
Q58095101Thy1 (CD90) expression is regulated by DNA methylation during adipogenesis
Q51089893Transcriptional Regulation of Adipogenesis
Q33753951Transcriptional control of preadipocyte determination by Zfp423.
Q34333066Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old wistar rats

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