Saturated Fatty Acid-induced cytotoxicity in liver cells does not involve phosphatase and tensin homologue deleted on chromosome 10.

scientific article published on 15 April 2013

Saturated Fatty Acid-induced cytotoxicity in liver cells does not involve phosphatase and tensin homologue deleted on chromosome 10. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1155/2013/514206
P932PMC publication ID3649318
P698PubMed publication ID23691291
P5875ResearchGate publication ID236925463

P2093author name stringDong Wang
Yuren Wei
Christopher L Gentile
Melinda Frye
Michael J Pagliassotti
P2860cites workUnsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN.Q47930991
Saturated but not mono-unsaturated fatty acids induce apoptotic cell death in neonatal rat ventricular myocytesQ73579716
Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitisQ73735584
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosisQ81441036
Free fatty acids induce JNK-dependent hepatocyte lipoapoptosisQ82677113
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphataseQ24322705
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver diseaseQ29619334
The critical role of AKT2 in hepatic steatosis induced by PTEN lossQ33816356
Triglyceride accumulation protects against fatty acid-induced lipotoxicityQ34866329
Lipotoxicity: when tissues overeatQ35168828
Non-alcoholic fatty liver disease and metabolic syndrome: what we know and what we don't knowQ36348723
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]Q36604703
Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cellsQ39616452
Saturated fatty acid-mediated endoplasmic reticulum stress and apoptosis are augmented by trans-10, cis-12-conjugated linoleic acid in liver cellsQ40147046
Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cellsQ40313352
A quantitative method for detection of spliced X-box binding protein-1 (XBP1) mRNA as a measure of endoplasmic reticulum (ER) stressQ40890620
Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturaseQ42563412
Stimulation of lipogenesis as well as fatty acid oxidation protects against palmitate-induced INS-1 beta-cell deathQ42761408
Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and functionQ43516835
Palmitate-induced apoptosis can occur through a ceramide-independent pathwayQ43559742
Nutritional and metabolic considerations in the etiology of nonalcoholic steatohepatitisQ43802817
Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver diseaseQ44664390
A lipidomic analysis of nonalcoholic fatty liver disease.Q44931121
Activation and dysregulation of the unfolded protein response in nonalcoholic fatty liver diseaseQ44934521
The lowering of hepatic fatty acid uptake improves liver function and insulin sensitivity without affecting hepatic fat content in humansQ46573417
PTEN down-regulation by unsaturated fatty acids triggers hepatic steatosis via an NF-kappaBp65/mTOR-dependent mechanismQ46827567
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectfatty acidQ61476
P304page(s)514206
P577publication date2013-04-15
P1433published inJournal of Nutrition and MetabolismQ26841852
P1476titleSaturated Fatty Acid-induced cytotoxicity in liver cells does not involve phosphatase and tensin homologue deleted on chromosome 10.
P478volume2013

Reverse relations

cites work (P2860)
Q91828800AEBP1 expression increases with severity of fibrosis in NASH and is regulated by glucose, palmitate, and miR-372-3p
Q53328225Exocrine pancreas ER stress is differentially induced by different fatty acids.
Q92351086Monounsaturated fatty acids protect against palmitate-induced lipoapoptosis in human umbilical vein endothelial cells

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