scholarly article | Q13442814 |
P819 | ADS bibcode | 2013PNAS..110.8105P |
P356 | DOI | 10.1073/PNAS.1221216110 |
P932 | PMC publication ID | 3657776 |
P698 | PubMed publication ID | 23620512 |
P5875 | ResearchGate publication ID | 236339543 |
P50 | author | Sabina Signoretti | Q90424571 |
P2093 | author name string | Ramesh A Shivdasani | |
Yan Geng | |||
Jean-Christophe Pignon | |||
Jiaxi Song | |||
Chiara Grisanzio | |||
P2860 | cites work | p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities | Q22003973 |
p63 is a prostate basal cell marker and is required for prostate development | Q24290591 | ||
Identification of a cell of origin for human prostate cancer | Q24594400 | ||
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells | Q28246460 | ||
p63 Is essential for the proliferative potential of stem cells in stratified epithelia | Q28300720 | ||
Role of p63 and basal cells in the prostate | Q28508984 | ||
p63 is the molecular switch for initiation of an epithelial stratification program | Q28512876 | ||
DeltaNp63 plays an anti-apoptotic role in ventral bladder development | Q28586002 | ||
p63 protects the female germ line during meiotic arrest | Q28586825 | ||
ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation | Q28587251 | ||
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development | Q28587664 | ||
p63 is a p53 homologue required for limb and epidermal morphogenesis | Q28588206 | ||
Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder | Q30540440 | ||
Cell biology and physiology of the uroepithelium | Q33570078 | ||
p63 regulates commitment to the prostate cell lineage | Q33913879 | ||
Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux | Q33925813 | ||
Squamous cell carcinoma of rectum presenting in a man: a case report | Q34461877 | ||
Distinct expression profiles of p63 variants during urothelial development and bladder cancer progression | Q34755858 | ||
A skin microRNA promotes differentiation by repressing 'stemness'. | Q34756894 | ||
A luminal epithelial stem cell that is a cell of origin for prostate cancer | Q35001982 | ||
Hormonal, cellular, and molecular control of prostatic development | Q35088639 | ||
Isolation and functional characterization of murine prostate stem cells | Q35250689 | ||
Regenerated luminal epithelial cells are derived from preexisting luminal epithelial cells in adult mouse prostate | Q35416465 | ||
p63 regulates olfactory stem cell self-renewal and differentiation | Q35619218 | ||
Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome | Q36037951 | ||
Proximal location of mouse prostate epithelial stem cells: a model of prostatic homeostasis | Q36324574 | ||
Colonic squamous cell carcinoma in ulcerative colitis: Report of a case and review of the literature | Q36709202 | ||
Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity | Q37094872 | ||
Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf. | Q37262994 | ||
Molecular pathways of urothelial development and bladder tumorigenesis | Q37770779 | ||
p63, a story of mice and men. | Q37862578 | ||
Self-renewal and multilineage differentiation in vitro from murine prostate stem cells. | Q40104557 | ||
p63 overexpression induces the expression of Sonic Hedgehog. | Q40218251 | ||
Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation | Q41484948 | ||
Differential expression of p63 isoforms in female reproductive organs | Q42478928 | ||
Multipotent and unipotent progenitors contribute to prostate postnatal development | Q42514100 | ||
p63 expression profiles in human normal and tumor tissues | Q42517203 | ||
Cell proliferation studies in rat prostate. I. The proliferative role of basal and secretory epithelial cells during normal growth | Q42522450 | ||
Epithelial development in the rat ventral prostate, anterior prostate and seminal vesicle | Q42523993 | ||
An unusual presentation of a cystic duplication of the sigmoid colon entirely lined with squamous epithelium. | Q51616069 | ||
Morphogenesis of ductal networks in the mouse prostate | Q69564996 | ||
Proximal prostatic stem cells are programmed to regenerate a proximal-distal ductal axis | Q83214461 | ||
P433 | issue | 20 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 8105-8110 | |
P577 | publication date | 2013-04-25 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | p63-expressing cells are the stem cells of developing prostate, bladder, and colorectal epithelia | |
P478 | volume | 110 |
Q35739462 | A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues. |
Q33953216 | A population of progenitor cells in the basal and intermediate layers of the murine bladder urothelium contributes to urothelial development and regeneration |
Q38292601 | A toolbox to study epidermal cell types in zebrafish. |
Q36332128 | Advanced neuroendocrine prostate tumors regress to stemness |
Q36272543 | Androgen Deprivation Accelerates the Prostatic Urethra Wound Healing After Thulium Laser Resection of the Prostate by Promoting Re-Epithelialization and Regulating the Macrophage Polarization |
Q64963951 | Androgen signaling is essential for development of prostate cancer initiated from prostatic basal cells. |
Q40199561 | Associations between RNA splicing regulatory variants of stemness-related genes and racial disparities in susceptibility to prostate cancer |
Q37076984 | Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks |
Q40843104 | Castration-resistant Lgr5(+) cells are long-lived stem cells required for prostatic regeneration |
Q35646380 | Cell kinetic studies fail to identify sequentially proliferating progenitors as the major source of epithelial renewal in the adult murine prostate |
Q92410874 | Cells of Origin for Prostate Cancer |
Q36485209 | Characterization of autoimmune inflammation induced prostate stem cell expansion |
Q35108553 | Clonal, self-renewing and differentiating human and porcine urothelial cells, a novel stem cell population. |
Q36780641 | Conditional ablation of p63 indicates that it is essential for embryonic development of the central nervous system |
Q37683681 | Contributions of epithelial-mesenchymal transition and cancer stem cells to the development of castration resistance of prostate cancer |
Q35049486 | Cytokeratin 15 marks basal epithelia in developing ureters and is upregulated in a subset of urothelial cell carcinomas |
Q34161127 | DEK promotes HPV-positive and -negative head and neck cancer cell proliferation. |
Q42247800 | Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors that Can Function as a Cell of Origin for Prostate Cancer |
Q39051019 | Development and stem cells of the esophagus |
Q40435708 | Differential diagnosis of bladder versus colorectal adenocarcinoma: keratin 7 and GATA3 positivity in nuclear ß-catenin-negative glandular tumours defines adenocarcinoma of the bladder |
Q90288420 | Direct conversion of fibroblasts into urothelial cells that may be recruited to regenerating mucosa of injured urinary bladder |
Q36262315 | Dual ligand/receptor interactions activate urothelial defenses against uropathogenic E. coli |
Q89454417 | EMT, stemness and tumor plasticity in aggressive variant neuroendocrine prostate cancers |
Q35586185 | Enrichment of Human Stem-Like Prostate Cells with s-SHIP Promoter Activity Uncovers a Role in Stemness for the Long Noncoding RNA H19. |
Q35674175 | Enrichment of the Cancer Stem Phenotype in Sphere Cultures of Prostate Cancer Cell Lines Occurs through Activation of Developmental Pathways Mediated by the Transcriptional Regulator ΔNp63α |
Q95321930 | Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers |
Q46365670 | Evolutionary re-wiring of p63 and the epigenomic regulatory landscape in keratinocytes and its potential implications on species-specific gene expression and phenotypes. |
Q38719945 | Expression profile of urothelial transcription factors in bladder biopsies with interstitial cystitis |
Q44053170 | Family matters: sibling rivalry and bonding between p53 and p63 in cancer |
Q58719886 | Genetic and scRNA-seq Analysis Reveals Distinct Cell Populations that Contribute to Salivary Gland Development and Maintenance |
Q42500743 | Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis |
Q59285937 | Glutathione Peroxidase 2, a Selenoprotein Exhibiting a Dual Personality in Preventing and Promoting Cancer |
Q35181159 | Hedgehog signaling in prostate epithelial-mesenchymal growth regulation |
Q49587907 | Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration. |
Q38184518 | How the TP53 family proteins TP63 and TP73 contribute to tumorigenesis: regulators and effectors |
Q36825219 | Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors. |
Q89555701 | Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate |
Q39165185 | Identification of potential bladder progenitor cells in the trigone |
Q52620813 | Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis. |
Q92711454 | Improvement of epidermal covering on AEC patients with severe skin erosions by PRIMA-1MET/APR-246 |
Q50018069 | Is it possible to give a single definition of the rectosigmoid junction? |
Q89818749 | Klf5 acetylation regulates luminal differentiation of basal progenitors in prostate development and regeneration |
Q47998717 | Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition. |
Q50144497 | Limbal stem cells: identity, developmental origin, and therapeutic potential. |
Q42291770 | Lineage Specification from Prostate Progenitor Cells Requires Gata3-Dependent Mitotic Spindle Orientation |
Q90196303 | Luminal-contact-inhibition of epithelial basal stem cell multipotency in prostate organogenesis and homeostasis |
Q38556654 | Maintaining epithelial stemness with p63. |
Q51731252 | Maternal protein malnutrition: effects on prostate development and adult disease. |
Q35925835 | Neuroendocrine Tumors of the Prostate: Emerging Insights from Molecular Data and Updates to the 2016 World Health Organization Classification |
Q34999132 | Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors |
Q36291156 | Nuclear iASPP may facilitate prostate cancer progression. |
Q35545782 | Pathway Regulation of p63, a Director of Epithelial Cell Fate |
Q38816754 | Phenotype plasticity rather than repopulation from CD90/CK14+ cancer stem cells leads to cisplatin resistance of urothelial carcinoma cell lines |
Q57789213 | Prostate Luminal Progenitor Cells in Development and Cancer |
Q47327615 | Prostate Organogenesis. |
Q35859467 | Prostate Sphere-forming Stem Cells Are Derived from the P63-expressing Basal Compartment. |
Q35132292 | Prostate adenocarcinomas aberrantly expressing p63 are molecularly distinct from usual-type prostatic adenocarcinomas |
Q35141115 | Prostate cancer and neuroendocrine differentiation: more neuronal, less endocrine? |
Q38321512 | Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression. |
Q39235902 | Prostate organogenesis: tissue induction, hormonal regulation and cell type specification |
Q42154804 | Prostate stem cells in the development of benign prostate hyperplasia and prostate cancer: emerging role and concepts |
Q27322357 | Quantitative lineage tracing strategies to resolve multipotency in tissue-specific stem cells |
Q100474460 | RUNX1 marks a luminal castration resistant lineage established at the onset of prostate development |
Q42498067 | Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program |
Q39709206 | Retinoid signaling in progenitors controls specification and regeneration of the urothelium |
Q35460065 | Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytes |
Q35617097 | Role of testicular luminal factors on Basal cell elongation and proliferation in the mouse epididymis |
Q96640898 | SIX1 cooperates with RUNX1 and SMAD4 in cell fate commitment of Müllerian duct epithelium |
Q52339863 | STAT3, stem cells, cancer stem cells and p63. |
Q62504753 | Salivary gland stem cells: A review of development, regeneration and cancer |
Q57294154 | Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin |
Q92623870 | Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome |
Q39103374 | Sleeping beauty: awakening urothelium from its slumber |
Q64240246 | Sox2 Expression Marks Castration-Resistant Progenitor Cells in the Adult Murine Prostate |
Q58698021 | Sphere-Formation Assay: Three-Dimensional Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells |
Q54246626 | Stem Cell Properties of Normal Human Keratinocytes Determine Transformation Responses to Human Papillomavirus 16 DNA. |
Q36637412 | Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer |
Q26784057 | Stem cells in genetically-engineered mouse models of prostate cancer |
Q92324289 | Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis |
Q42464662 | Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages |
Q37601733 | T-cadherin in prostate cancer: relationship with cancer progression, differentiation and drug resistance |
Q38889490 | Targeting cancer stem-like cells in glioblastoma and colorectal cancer through metabolic pathways |
Q90457679 | The Urothelium: Life in a Liquid Environment |
Q37565312 | The essential role of GATA transcription factors in adult murine prostate |
Q36751520 | The function of Drosophila p53 isoforms in apoptosis |
Q35683471 | The long noncoding RNA HOTAIR has tissue and cell type-dependent effects on HOX gene expression and phenotype of urothelial cancer cells |
Q50455437 | The p53 family members have distinct roles during mammalian embryonic development |
Q34157832 | The prostate basal cell (BC) heterogeneity and the p63-positive BC differentiation spectrum in mice |
Q93145668 | Therapeutic potential of intravesical injections of platelet-rich plasma in the treatment of lower urinary tract disorders due to regenerative deficiency |
Q55096065 | Tissue engineering for urinary tract reconstruction and repair: Progress and prospect in China. |
Q50594294 | Tissue-specific roles of FGF signaling in external genitalia development. |
Q51417555 | Transcriptional Regulation in Prostate Cancer. |
Q42120830 | Transcriptome profiling links the intrinsic properties of human prostate basal cells to prostate cancer aggressiveness. |
Q33815791 | Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer. |
Q35859471 | Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment |
Q38541294 | Uroplakin 1b is critical in urinary tract development and urothelial differentiation and homeostasis |
Q42505148 | Urothelial cell expansion and differentiation are improved by exposure to hypoxia |
Q39097235 | Urothelial generation and regeneration in development, injury, and cancer. |
Q42507514 | Urothelial proliferation and regeneration after spinal cord injury |
Q33631065 | p63+ ureteric bud tip cells are progenitors of intercalated cells |
Q41260235 | s-SHIP expression identifies a subset of murine basal prostate cells as neonatal stem cells |
Q41727778 | ΔNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis |
Q41354391 | ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion |
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