Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus

scientific article published on July 1986

Phosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID253040
P698PubMed publication ID2423705

P2093author name stringT Hunter
B M Sefton
T Patschinsky
P2860cites workEvidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoproteinQ24297885
Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src)Q24618435
Amino-terminal sequence analysis of alphavirus polypeptidesQ27477807
Transforming gene product of Rous sarcoma virus phosphorylates tyrosineQ29620005
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylationQ33931404
Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virusQ34254297
Tyr527 is phosphorylated in pp60c-src: implications for regulationQ34383180
Evidence that there exist four classes of RNA tumor viruses which encode proteins with associated tyrosine protein kinase activitiesQ35239618
Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylationQ36281307
Relationship of polypeptide products of the transforming gene of Rous sarcoma virus and the homologous gene of vertebratesQ36363952
Structural analysis of the avian sarcoma virus transforming protein: sites of phosphorylationQ36493768
Polymorphism of avian sarcoma virus src proteinsQ36496786
Characterization of Rous sarcoma virus src gene products synthesized in vitroQ36526354
The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activityQ36862547
DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src.Q36924844
Antiserum specific for the carboxy terminus of the transforming protein of Rous sarcoma virusQ36926320
Evidence the pp60src, the product of the Rous sarcoma virus src gene, undergoes autophosphorylationQ36936361
Phosphorylation and metabolism of the transforming protein of Rous sarcoma virusQ36939222
Structurally and functionally modified forms of pp60v-src in Rous sarcoma virus-transformed cell lysatesQ36945448
Protein kinase activity associated with the avian sarcoma virus src gene productQ37584831
Comparison of the expression of the src gene of Rous sarcoma virus in vitro and in vivoQ37601190
Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinaseQ40078836
Efficient fluorography of 3H and 14C on thin layersQ40181554
Effects of local cell concentrations upon the growth of chick embryo cells in tissue cultureQ44175427
Local mutagenesis of Rous sarcoma virus: The major sites of tyrosine and serine phosphorylation of p60src are dispensable for transformationQ45797801
Cyclic AMP treatment of Rous sarcoma virus-transformed Chinese hamster ovary cells increases phosphorylation of pp60src and increases pp60src kinase activityQ45797944
Nucleotide sequence of Rous sarcoma virusQ45798778
Corrections to the nucleotide sequence of the src gene of Rous sarcoma virusQ45798865
Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virusQ45803202
Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosineQ45803653
Frameshift and intragenic suppressor mutations in a rous sarcoma provirus suggest src encodes two proteinsQ48399723
Protein kinase C phosphorylates pp60src at a novel site.Q48450716
Site-specific increased phosphorylation of pp60v-src after treatment of RSV-transformed cells with a tumor promoter.Q53542383
The stimulation of pp60v-src kinase activity by vanadate in intact cells accompanies a new phosphorylation state of the enzymeQ53551151
Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro.Q53552017
Phosphorylation of tyrosine-416 is not required for the transforming properties and kinase activity of pp60v-src.Q53560402
The calmodulin-dependent glycogen synthase kinase from rabbit skeletal muscle. Purification, subunit structure and substrate specificityQ70175039
In vitro phosphorylation of angiotensin analogs by tyrosyl protein kinasesQ71653879
A mutation at the major phosphotyrosine in pp60v-src alters oncogenic potentialQ72741286
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
Rous sarcoma virusQ1444330
P304page(s)73-81
P577publication date1986-07-01
P1433published inJournal of VirologyQ1251128
P1476titlePhosphorylation of the transforming protein of Rous sarcoma virus: direct demonstration of phosphorylation of serine 17 and identification of an additional site of tyrosine phosphorylation in p60v-src of Prague Rous sarcoma virus
P478volume59