Zinc(II)-Dipicolylamine Coordination Complexes as Targeting and Chemotherapeutic Agents for Leishmania major

scientific article published on 29 February 2016

Zinc(II)-Dipicolylamine Coordination Complexes as Targeting and Chemotherapeutic Agents for Leishmania major is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.00410-16
P932PMC publication ID4862449
P698PubMed publication ID26926632

P2093author name stringBradley D Smith
Miguel A Morales
Paola Vacchina
Brianna Norris-Mullins
Douglas R Rice
P2860cites workFluorescent detection of apoptotic cells by using zinc coordination complexes with a selective affinity for membrane surfaces enriched with phosphatidylserineQ40353282
Amphotericin versus pentamidine in antimony-unresponsive kala-azarQ40726692
Bacterial imaging and photodynamic inactivation using zinc(II)-dipicolylamine BODIPY conjugatesQ41170348
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A limiting dilution assay for quantifying Leishmania major in tissues of infected miceQ44935160
The mechanism behind the antileishmanial effect of zinc sulphate. II. Effects on the enzymes of the parasitesQ46425197
In vitro activity of dicationic compounds against a North American foxhound isolate of Leishmania infantumQ46448466
Experimental selection of paromomycin and miltefosine resistance in intracellular amastigotes of Leishmania donovani and L. infantumQ46921246
Synthesis and in vitro evaluation of leishmanicidal and trypanocidal activities of N-quinolin-8-yl-arylsulfonamidesQ46986306
An in vitro system for developmental and genetic studies of Leishmania donovani phosphoglycans.Q47450122
Lipid analyses of isolated surface membranes of Leishmania donovani promastigotes.Q52466989
Genetic variability within the species Leishmania infantum by RAPD. A lack of correlation with zymodeme structureQ77556557
Zinc sulphate in the treatment of cutaneous leishmaniasis: an in vitro and animal studyQ77913800
Selective recognition of bacterial membranes by zinc(II)-coordination complexesQ83047107
Optical imaging of bacterial infection in living mice using a fluorescent near-infrared molecular probeQ24653803
Leishmaniasis: current status of available drugs and new potential drug targetsQ27001898
The increase in risk factors for leishmaniasis worldwideQ28211413
Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasisQ28271849
Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasisQ28485377
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.Q30417002
Leishmanicidal activity of stearylamine-bearing liposomes in vitroQ32066670
Antileishmanial activities of stearylamine-bearing liposomesQ33979887
Leishmaniasis: current situation and new perspectivesQ34330071
Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatmentQ34369251
Anti Leishmanial Effect of Zinc Sulphate on the Viability of Leishmania tropica and L. major Promastigotes.Q34629567
The immunological, environmental, and phylogenetic perpetrators of metastatic leishmaniasis.Q34871440
Effect of Bridging Anions on the Structure and Stability of Phenoxide Bridged Zinc Dipicolylamine Coordination ComplexesQ34892341
Library synthesis, screening, and discovery of modified Zinc(II)-Bis(dipicolylamine) probe for enhanced molecular imaging of cell death.Q35103904
Use of antimony in the treatment of leishmaniasis: current status and future directionsQ35377767
The lipophosphoglycan of Leishmania parasitesQ35534721
Chromosome and gene copy number variation allow major structural change between species and strains of LeishmaniaQ35581571
Metal complexes as chemotherapeutic agents against tropical diseases: trypanosomiasis, malaria and leishmaniasisQ35644519
Multicolor fluorescence imaging of traumatic brain injury in a cryolesion mouse modelQ36104487
Phosphatidylserine exposure on the surface of Leishmania amazonensis amastigotes modulates in vivo infection and dendritic cell functionQ36589026
Sitamaquine as a putative antileishmanial drug candidate: from the mechanism of action to the risk of drug resistanceQ36899150
Biochemistry of the Leishmania speciesQ37064669
LiZIP3 is a cellular zinc transporter that mediates the tightly regulated import of zinc in Leishmania infantum parasitesQ37134032
Systematic review of the adverse effects of cutaneous leishmaniasis treatment in the New World.Q37855193
Antimicrobial peptides as parasiticidal against human trypanosomatids: mechanisms of action and current status in developmentQ38108611
In vitro screening test using Leishmania promastigotes stably expressing mCherry proteinQ38324287
Enhanced cell death imaging using multivalent zinc(II)-bis(dipicolylamine) fluorescent probesQ39115370
In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc-dipicolylamine probeQ39307808
In vitro anti-leishmania evaluation of nickel complexes with a triazolopyrimidine derivative against Leishmania infantum and Leishmania braziliensis.Q39357153
Optical imaging of mammary and prostate tumors in living animals using a synthetic near infrared zinc(II)-dipicolylamine probe for anionic cell surfacesQ39762666
Optical Imaging of Bacterial Infection ModelsQ39888990
Noninvasive optical imaging of staphylococcus aureus bacterial infection in living mice using a Bis-dipicolylamine-Zinc(II) affinity group conjugated to a near-infrared fluorophore.Q39982027
P4510describes a project that usesImageJQ1659584
ImageQuantQ112270642
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectchemotherapyQ974135
Leishmania majorQ1950715
P1104number of pages9
P304page(s)2932-2940
P577publication date2016-02-29
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleZinc(II)-Dipicolylamine Coordination Complexes as Targeting and Chemotherapeutic Agents for Leishmania major
P478volume60

Reverse relations

cites work (P2860)
Q39396680Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes
Q53375546Glycosylated metal chelators as anti-parasitic agents with tunable selectivity.
Q38853138Imaging and therapeutic applications of zinc(ii)-dipicolylamine molecular probes for anionic biomembranes
Q38719334Preassembled Fluorescent Multivalent Probes for the Imaging of Anionic Membranes.
Q90349889Zinc-Chelating Small Molecules Preferentially Accumulate and Function within Pancreatic β Cells

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