Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients

scientific article published on January 2007

Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1044763909
P356DOI10.2165/00003495-200767110-00004
P698PubMed publication ID17661528

P50authorGeorg MaschmeyerQ88881628
Oliver A CornelyQ57062280
P2093author name stringAntje Haas
P2860cites workVoriconazole compared with liposomal amphotericin B for empirical antifungal therapy in patients with neutropenia and persistent feverQ28216366
Voriconazole versus amphotericin B for primary therapy of invasive aspergillosisQ28217179
1,3-beta-D-glucan in patients receiving intravenous amoxicillin-clavulanic acidQ28249155
Multicenter clinical evaluation of the (1-->3) beta-D-glucan assay as an aid to diagnosis of fungal infections in humansQ28265703
Beta-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndromeQ28276727
Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trialQ28277029
Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropeniaQ28284944
Liposomal amphotericin B as initial therapy for invasive mold infection: a randomized trial comparing a high-loading dose regimen with standard dosing (AmBiLoad trial)Q28298468
Comparison of effects of amphotericin B deoxycholate infused over 4 or 24 hours: randomised controlled trialQ28359772
Clinical significance of nephrotoxicity in patients treated with amphotericin B for suspected or proven aspergillosisQ28377349
Plasma (1-->3)-beta-D-glucan measurement in diagnosis of invasive deep mycosis and fungal febrile episodesQ29038934
Epidemiology of visceral mycoses: analysis of data in annual of the pathological autopsy cases in JapanQ30577215
Amphotericin B colloidal dispersion (Amphocil) vs fluconazole for the prevention of fungal infections in neutropenic patients: data of a prematurely stopped clinical trialQ30596268
Amphotericin B vs fluconazole for controlling fungal infections in neutropenic cancer patientsQ30887333
Liposomal amphotericin B (AmBisome): safety data from a phase II/III clinical trialQ31125591
Fluconazole vs low-dose amphotericin B for the prevention of fungal infections in patients undergoing bone marrow transplantation: a study of the North American Marrow Transplant GroupQ31372000
Aspergillosis case-fatality rate: systematic review of the literatureQ31918085
Mortality and costs of acute renal failure associated with amphotericin B therapyQ32068576
Therapeutic role of alemtuzumab (Campath-1H) in patients who have failed fludarabine: results of a large international studyQ33342242
Contribution of (1->3)-beta-D-glucan chromogenic assay to diagnosis and therapeutic monitoring of invasive aspergillosis in neutropenic adult patients: a comparison with serial screening for circulating galactomannanQ33592749
Liposomal amphotericin B for empirical therapy in patients with persistent fever and neutropenia. National Institute of Allergy and Infectious Diseases Mycoses Study GroupQ33854646
False positivity for Aspergillus antigenemia with amoxicillin-clavulonic acidQ33859221
Practice guidelines for diseases caused by Aspergillus. Infectious Diseases Society of AmericaQ33894472
Current status of nonculture methods for diagnosis of invasive fungal infectionsQ33906498
A multicenter, open-label clinical study of micafungin (FK463) in the treatment of deep-seated mycosis in JapanQ33980368
Safety, tolerance, and pharmacokinetics of high-dose liposomal amphotericin B (AmBisome) in patients infected with Aspergillus species and other filamentous fungi: maximum tolerated dose studyQ33983629
Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes. I3 Aspergillus Study GroupQ34002098
Antifungal prophylaxis for solid organ transplant recipients: seeking clarity amidst controversyQ34033598
Management of invasive pulmonary aspergillosis in hematology patients: a review of 87 consecutive cases at a single institutionQ34069443
Use of real-time PCR to process the first galactomannan-positive serum sample in diagnosing invasive aspergillosisQ34073294
2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancerQ34114674
A study of consecutive autopsies in a medical ICU : a comparison of clinical cause of death and autopsy diagnosisQ34137012
An overview of fungal infectionsQ34162712
Pathogenic molds (including Aspergillus species) in hospital water distribution systems: a 3-year prospective study and clinical implications for patients with hematologic malignanciesQ34162934
Hospital infection control in hematopoietic stem cell transplant recipientsQ34213683
Epidemiology of fungal infections in solid organ transplant patientsQ34294864
Intravenous and oral itraconazole versus intravenous amphotericin B deoxycholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-spectrum antibacterial therapy. A randomized, controlleQ40596481
Infectious complications after high-dose chemotherapy and autologous stem cell transplantation: comparison between patients with lymphoma or multiple myeloma and patients with solid tumorsQ40604160
Intensive intravenous amphotericin B for prophylaxis of systemic fungal infections. Results of a prospective controlled pilot study in acute leukemia patientsQ40619933
A randomized comparison of liposomal versus conventional amphotericin B for the treatment of pyrexia of unknown origin in neutropenic patientsQ40645972
Pulmonary infiltrations in febrile patients with neutropenia. Risk factors and outcome under empirical antimicrobial therapy in a randomized multicenter studyQ40701026
Evaluation of a (1->3)-beta-D-glucan assay for diagnosis of invasive fungal infectionsQ40708990
Differences in patterns of infection and inflammation for corticosteroid treatment and chemotherapy in experimental invasive pulmonary aspergillosisQ40734608
The efficacy of itraconazole against systemic fungal infections in neutropenic patients: A randomised comparative study with amphotericin BQ40754163
Invasive pulmonary aspergillosis in adult acute leukemia: clinical clues to its diagnosisQ40816306
Empiric antibiotic and antifungal therapy for cancer patients with prolonged fever and granulocytopeniaQ40847963
Comparative analysis of prognostic indicators of aspergillosis in haematological malignancies and HIV infection.Q40913472
Infectious complications of autologous bone marrow and peripheral stem cell transplantation for refractory leukemia and lymphoma.Q40931570
Risk of reactivation of a recent invasive fungal infection in patients with hematological malignancies undergoing further intensive chemo-radiotherapy. A single-center experience and review of the literatureQ41542963
Burn wound infections: current statusQ41694816
Clinical relevance of Aspergillus isolation from respiratory tract samples in critically ill patientsQ41998776
A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.Q42048818
In vitro release by Aspergillus fumigatus of galactofuranose antigens, 1,3-beta-D-glucan, and DNA, surrogate markers used for diagnosis of invasive aspergillosisQ42068116
Prevention of amphotericin-B-induced nephrotoxicity by loading with sodium chloride: a report of 1291 days of treatment with amphotericin B without renal failureQ42191679
Antifungal prophylaxis during remission induction therapy for acute leukemia fluconazole versus intravenous amphotericin B.Q42285296
NIAID Mycoses Study Group Multicenter Trial of Oral Itraconazole Therapy for Invasive AspergillosisQ42599568
Use of galactomannan enzyme immunoassay for diagnosis of invasive aspergillosis in a tertiary-care center over a 12-month periodQ42911728
Plasmalyte as a cause of false-positive results for Aspergillus galactomannan in bronchoalveolar lavage fluidQ42912557
Recovery of filamentous fungi from water in a paediatric bone marrow transplantation unit.Q43341736
Bacteraemia during the aplastic phase after allogeneic bone marrow transplantation is associated with early death from invasive fungal infectionQ43416427
Cyclophosphamide metabolism is affected by azole antifungalsQ43530745
Invasive pulmonary aspergillosis in neutropenic patients during hospital construction: before and after chemoprophylaxis and institution of HEPA filtersQ43560592
Congestive heart failure associated with itraconazoleQ43638251
Itraconazole versus amphotericin B plus nystatin in the prophylaxis of fungal infections in neutropenic cancer patientsQ43648084
Intravenous itraconazole followed by oral itraconazole in the treatment of invasive pulmonary aspergillosis in patients with hematologic malignancies, chronic granulomatous disease, or AIDS.Q43732838
Aerosolized amphotericin B inhalations as prophylaxis of invasive aspergillus infections during prolonged neutropenia: results of a prospective randomized multicenter trial.Q43788508
Intravenous and oral itraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients. A multicenter, randomized trialQ43801360
Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosisQ43864353
Aspergillosis due to carpet contamination.Q43874390
Why prior fluconazole use is associated with an increased risk of invasive mold infections in immunosuppressed hosts: an alternative hypothesisQ43952852
Imaging findings in acute invasive pulmonary aspergillosis: clinical significance of the halo signQ44023091
Prophylactic administration of liposomal amphotericin B is superior to treatment in a murine model of invasive aspergillosis after hematopoietic cell transplantationQ44045004
Antifungal prophylaxis for severely neutropenic chemotherapy recipients: a meta analysis of randomized-controlled clinical trialsQ44062340
Concentrations of airborne Aspergillus compared to the incidence of invasive aspergillosis: lack of correlationQ44160630
Refractory Aspergillus pneumonia in patients with acute leukemia: successful therapy with combination caspofungin and liposomal amphotericinQ44304226
Continuous infusion of escalated doses of amphotericin B deoxycholate: an open-label observational studyQ44396642
Combination therapy in treatment of experimental pulmonary aspergillosis: synergistic interaction between an antifungal triazole and an echinocandinQ44469440
Influence of high-efficiency particulate air filtration on mortality and fungal infection: a rebuttalQ44479147
Efficacy and toxicity of caspofungin in combination with liposomal amphotericin B as primary or salvage treatment of invasive aspergillosis in patients with hematologic malignanciesQ44519647
Treatment of fungal infections in hematology and oncology--guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).Q44589098
Efficacy and safety of itraconazole prophylaxis for fungal infections after orthotopic liver transplantation: a prospective, randomized, double-blind studyQ44595697
Treatment failure in invasive aspergillosis: susceptibility of deep tissue isolates following treatment with amphotericin B.Q44602927
Itraconazole versus fluconazole for prevention of fungal infections in patients receiving allogeneic stem cell transplantsQ44606439
False positive test for aspergillus antigenemia related to concomitant administration of piperacillin and tazobactam.Q44688423
Itraconazole prevents invasive fungal infections in neutropenic patients treated for hematologic malignancies: evidence from a meta-analysis of 3,597 patientsQ44691631
Lipid formulations of amphotericin B preserve and stabilize renal function in HSCT recipientsQ44733428
False-positive galactomannan platelia Aspergillus test results for patients receiving piperacillin-tazobactam.Q44785839
Treatment with piperacillin-tazobactam and false-positive Aspergillus galactomannan antigen test results for patients with hematological malignanciesQ44785842
Secondary antifungal prophylaxis with voriconazole to adhere to scheduled treatment in leukemic patients and stem cell transplant recipientsQ44807745
Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover studyQ44832013
Itraconazole versus fluconazole for antifungal prophylaxis.Q44833684
Infections due to Aspergillus terreus: a multicenter retrospective analysis of 83 casesQ45015455
False-positive Aspergillus galactomannan antigen test resultsQ45015468
Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: evidence of concentration-dependent activityQ45066131
New cause for false-positive results with the Pastorex Aspergillus antigen latex agglutination test.Q37133728
10 year review of invasive aspergillosis detected at necropsyQ37141726
False-positive Aspergillus galactomannan enzyme-linked immunosorbent assay results in vivo during amoxicillin-clavulanic acid treatmentQ37597610
Fungal burn wound infection. A 10-year experienceQ37621397
Nosocomial aspergillosis: environmental microbiology, hospital epidemiology, diagnosis and treatmentQ38679942
Fungal contamination of food in hematology units.Q39462272
In vitro synergy of caspofungin and amphotericin B against Aspergillus and Fusarium spp.Q39651019
Efficacy of caspofungin alone and in combination with voriconazole in a Guinea pig model of invasive aspergillosisQ39652561
Opportunistic fungal infection of the burn wound with phycomycetes and Aspergillus. A clinical-pathologic reviewQ40062077
Nosocomial aspergillosis: a retrospective review of airborne disease secondary to road construction and contaminated air conditionersQ40244250
Prognostic factors for death due to invasive aspergillosis after hematopoietic stem cell transplantation: a 1-year retrospective study of consecutive patients at French transplantation centersQ40346459
Efficacy and toxicity of intermediate-dose amphotericin B lipid complex as a primary or salvage treatment of fungal infections in patients with hematological malignanciesQ40384862
A prospective, randomized multicenter trial of the empirical addition of antifungal therapy for febrile neutropenic cancer patients: results of the Paul Ehrlich Society for Chemotherapy (PEG) Multicenter Trial II.Q40475785
Usefulness of sequential Aspergillus galactomannan antigen detection combined with early radiologic evaluation for diagnosis of invasive pulmonary aspergillosis in patients undergoing allogeneic stem cell transplantation.Q40475979
Galactomannan and computed tomography-based preemptive antifungal therapy in neutropenic patients at high risk for invasive fungal infection: a prospective feasibility studyQ40497134
Caspofungin as second-line therapy for fever of unknown origin or invasive fungal infection following allogeneic stem cell transplantationQ40513418
Risk factors for invasive aspergillosis in neutropenic patients with hematologic malignanciesQ40514264
Direct detection of angioinvasive pulmonary aspergillosis in immunosuppressed patients: preliminary results with high-resolution 16-MDCT angiographyQ40514353
Caspofungin versus liposomal amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropeniaQ40524745
Amphotericin B lipid complex as prophylaxis of invasive fungal infections in patients with acute myelogenous leukemia and myelodysplastic syndrome undergoing induction chemotherapyQ40541356
Antimicrobial therapy of unexplained fever in neutropenic patients--guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO), Study Group Interventional Therapy of Unexplained Fever, ArbeitsQ40550138
Diagnosis and antimicrobial therapy of pulmonary infiltrates in febrile neutropenic patients--guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).Q40550143
Use of circulating galactomannan screening for early diagnosis of invasive aspergillosis in allogeneic stem cell transplant recipientsQ40572100
A double-blind, randomized, controlled trial of amphotericin B colloidal dispersion versus amphotericin B for treatment of invasive aspergillosis in immunocompromised patientsQ40577742
Aspergillus galactomannan detection in the diagnosis of invasive aspergillosis in cancer patientsQ40585861
Autologous peripheral blood stem cell transplant in patients previously diagnosed with invasive aspergillosisQ40596372
High level of recovery of fungi from water and dialysate in haemodialysis unitsQ74008136
Fungal colonization of air filters from hospitalsQ74026068
Invasive aspergillosisQ74492548
Itraconazole oral solution as prophylaxis for fungal infections in neutropenic patients with hematologic malignancies: a randomized, placebo-controlled, double-blind, multicenter trial. GIMEMA Infection Program. Gruppo Italiano Malattie EmatologicheQ74579178
Survival and prognostic factors of invasive aspergillosis after allogeneic bone marrow transplantationQ74579207
Pulmonary Aspergillus colonization in humans and its impact on management of critically ill patientsQ77228210
Antifungal prophylaxis with itraconazole in neutropenic patients with acute leukaemiaQ77299304
Early infections in patients undergoing bone marrow or blood stem cell transplantation--a 7 year single centre investigation of 409 casesQ77366207
Prediction of invasive pulmonary aspergillosis from colonisation of lower respiratory tract before marrow transplantationQ77530137
Invasive aspergillosis in neutropenic patients: rapid neutrophil recovery is a risk factor for severe pulmonary complicationsQ77829261
Variable number of tandem repeats of TNF receptor type 2 promoter as genetic biomarker of susceptibility to develop invasive pulmonary aspergillosisQ79506947
Paradoxical increase in circulating Aspergillus antigen during treatment with caspofungin in a patient with pulmonary aspergillosisQ79804764
Interleukin-10 promoter polymorphism as risk factor to develop invasive pulmonary aspergillosisQ79829012
Prospective study of amphotericin B formulations in immunocompromised patients in 4 European countriesQ79895605
Long-term CT follow-up in 40 non-HIV immunocompromised patients with invasive pulmonary aspergillosis: kinetics of CT morphology and correlation with clinical findings and outcomeQ79966887
Detection of Aspergillus galactomannan by enzyme immunoabsorbent assay in recipients of allogeneic hematopoietic stem cell transplantation: a prospective studyQ80008313
Delayed ABLC prophylaxis after allogeneic stem-cell transplantationQ80146502
Prospective comparison of the diagnostic potential of real-time PCR, double-sandwich enzyme-linked immunosorbent assay for galactomannan, and a (1-->3)-beta-D-glucan test in weekly screening for invasive aspergillosis in patients with hematologicalQ80174046
Kinetics of galactomannan in surgical patients receiving perioperative piperacillin/tazobactam prophylaxisQ80192309
Triazole-polyene antagonism in experimental invasive pulmonary aspergillosis: in vitro and in vivo correlationQ80231148
Invasive aspergillosis in critically ill patients without malignancyQ80269940
Detection of galactomannan antigenemia by enzyme immunoassay for the diagnosis of invasive aspergillosis: variables that affect performanceQ80312940
Prospective clinical evaluation of lower cut-offs for galactomannan detection in adult neutropenic cancer patients and haematological stem cell transplant recipientsQ80536933
Predicting outcome after lung resection for invasive pulmonary aspergillosis in patients with neutropeniaQ81134376
Protective role of interleukin-10 promoter gene polymorphism in the pathogenesis of invasive pulmonary aspergillosis after allogeneic stem cell transplantationQ81398889
Galactomannan and the diagnosis of invasive aspergillosisQ83163314
A prospective randomized trial of itraconazole vs fluconazole for the prevention of fungal infections in patients with acute leukemia and hematopoietic stem cell transplant recipientsQ83919477
Invasive fungal infections in patients with hematologic malignancies in a tertiary care cancer center: an autopsy study over a 15-year period (1989-2003)Q83938057
Open-label, randomized comparison of itraconazole versus caspofungin for prophylaxis in patients with hematologic malignanciesQ34301513
Safety and pharmacokinetics of intravenous anidulafungin in children with neutropenia at high risk for invasive fungal infectionsQ34352100
Micafungin versus fluconazole for prophylaxis against invasive fungal infections during neutropenia in patients undergoing hematopoietic stem cell transplantationQ34368144
Zygomycosis in a tertiary-care cancer center in the era of Aspergillus-active antifungal therapy: a case-control observational study of 27 recent casesQ34404335
Occurrence and kinetics of false-positive Aspergillus galactomannan test results following treatment with beta-lactam antibiotics in patients with hematological disorders.Q34430636
Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus.Q34455633
Epidemiology and outcome of infections due to Aspergillus terreus: 10-year single centre experienceQ34455699
Diagnosis of invasive aspergillosis using a galactomannan assay: a meta-analysisQ34514484
Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipientsQ34553509
Safety and tolerability of caspofungin acetate in the treatment of fungal infectionsQ34746958
Evidence-based assessment of primary antifungal prophylaxis in patients with hematologic malignanciesQ34977257
Summary: future directions in antifungal therapyQ35027508
Impact of current transplantation practices on the changing epidemiology of infections in transplant recipientsQ35076852
In vivo pharmacodynamics of antifungal drugs in treatment of candidiasisQ35091285
Clinical pharmacology of antifungal compoundsQ35129039
Itraconazole resistance in Aspergillus fumigatusQ35136791
Combination and sequential antifungal therapy for invasive aspergillosis: review of published in vitro and in vivo interactions and 6281 clinical cases from 1966 to 2001.Q35219729
Detection of Aspergillus DNA in cerebrospinal fluid from patients with cerebral aspergillosis by a nested PCR assayQ35220840
Prophylaxis of invasive fungal infections in patients with hematological malignancies and solid tumors--guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Oncology (DGHO).Q35298777
Aspergillus antigen testing in bone marrow transplant recipientsQ35396243
Fatal haemoptysis associated with invasive pulmonary aspergillosis treated with high-dose amphotericin B and granulocyte-macrophage colony-stimulating factor (GM-CSF).Q35529418
Efficacy, safety and cost-effectiveness of Amphotericin B Lipid Complex (ABLC): a review of the literatureQ35761396
Update on the treatment of cerebral aspergillosisQ35763586
Detection of circulating galactomannan for the diagnosis and management of invasive aspergillosisQ35789251
A consensus on fungal polymerase chain reaction diagnosis?: a United Kingdom-Ireland evaluation of polymerase chain reaction methods for detection of systemic fungal infectionsQ35790217
Impact of the intensity of the pretransplantation conditioning regimen in patients with prior invasive aspergillosis undergoing allogeneic hematopoietic stem cell transplantation: A retrospective survey of the Infectious Diseases Working Party of thQ35849045
Utility of Aspergillus antigen detection in specimens other than serum specimensQ35951605
Pulmonary infections after bone marrow transplantation: high-resolution CT findings in 111 patientsQ36240071
Spectrum of infection, risk and recommendations for prophylaxis and screening among patients with lymphoproliferative disorders treated with alemtuzumab*.Q36349776
Campath-1H induction and the incidence of infectious complications in adult renal transplantationQ36371927
The influence of high-efficiency particulate air filtration on mortality and fungal infection among highly immunosuppressed patients: a systematic reviewQ36451064
Comparison of antigen detection and PCR assay using bronchoalveolar lavage fluid for diagnosing invasive pulmonary aspergillosis in patients receiving treatment for hematological malignanciesQ36526353
Detection and identification of fungal pathogens in blood by using molecular probes.Q36544360
Prospective evaluation of a polymerase chain reaction-ELISA targeted to Aspergillus fumigatus and Aspergillus flavus for the early diagnosis of invasive aspergillosis in patients with hematological malignancies.Q54619719
Epidemiological study of invasive pulmonary aspergillosis in a haematology unit by molecular typing of environmental and patient isolates of Aspergillus fumigatus.Q54671391
Prospective clinical evaluation of a LightCycler-mediated polymerase chain reaction assay, a nested-PCR assay and a galactomannan enzyme-linked immunosorbent assay for detection of invasive aspergillosis in neutropenic cancer patients and haematologQ54723179
Epidemiology of invasive aspergillosis in France: a six-year multicentric survey in the Greater Paris areaQ56941303
Environmental sampling for aspergilli during building construction on a hospital siteQ57135750
Trends in Risk Profiles for and Mortality Associated with Invasive Aspergillosis among Liver Transplant RecipientsQ57569380
TLR1 and TLR6 Polymorphisms Are Associated with Susceptibility to Invasive Aspergillosis after Allogeneic Stem Cell TransplantationQ57908265
Invasive fungal infections after allogeneic peripheral blood stem cell transplantation: incidence and risk factors in 395 patientsQ58865962
Voriconazole Prophylaxis in Lung Transplant RecipientsQ59230762
Galactomannan Does Not Precede Major Signs on a Pulmonary Computerized Tomographic Scan Suggestive of Invasive Aspergillosis in Patients with Hematological MalignanciesQ59308866
Infectious complications in 126 patients treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantationQ59312591
The Effect of Prophylactic Fluconazole on the Clinical Spectrum of Fungal Diseases in Bone Marrow Transplant Recipients with Special Attention to Hepatic Candidiasis: An Autopsy Study of 355 PatientsQ59512024
Epidemiology ofAspergillusInfections in a Large Cohort of Patients Undergoing Bone Marrow TransplantationQ59512032
Risk factors for treatment failures in patients receiving PCR-based preemptive therapy for CMV infectionQ60029223
Multicenter, noncomparative study of caspofungin in combination with other antifungals as salvage therapy in adults with invasive aspergillosisQ61758327
Liposomal amphotericin B compared with amphotericin B deoxycholate in the treatment of documented and suspected neutropenia-associated invasive fungal infectionsQ61758371
Multiple-Triazole–Resistant AspergillosisQ63914862
Empiric antifungal therapy in febrile granulocytopenic patients. EORTC International Antimicrobial Therapy Cooperative GroupQ64132952
Infection prevention in acute nonlymphocytic leukemia. Laminar air flow room reverse isolation with oral, nonabsorbable antibiotic prophylaxisQ66841111
Aspergillus Infection of the Burn WoundQ66944772
Treatment of invasive aspergillosis: relation of early diagnosis and treatment to responseQ67561741
Aspergillus infections in cancer patients. Association with fireproofing materials in a new hospitalQ67770550
Endemic and epidemic aspergillosis associated with in-hospital replication of Aspergillus organismsQ68043033
Nosocomial fungal infection during hospital renovationQ69817516
Prophylactic use of liposomal amphotericin B (AmBisome) against fungal infections: a randomized trial in bone marrow transplant recipientsQ70582486
Pulmonary aspergillosis: early diagnosis improves survivalQ70877231
Kitchens as a source of Aspergillus niger infectionQ71217133
Prolonged granulocytopenia: the major risk factor for invasive pulmonary aspergillosis in patients with acute leukemiaQ71268640
Autologous bone marrow transplantation is feasible in patients with a prior history of invasive pulmonary aspergillosisQ71299234
Fungal prophylaxis with AmBisome in liver and bone marrow transplant recipients: results of two randomized double-blind studiesQ72058165
Evolving risk factors for invasive fungal infections--all neutropenic patients are not the sameQ72160665
Low incidence of invasive fungal infections after bone marrow transplantation in patients receiving amphotericin B inhalations during neutropeniaQ72248781
Randomized double-blind study of liposomal amphotericin B (Ambisome) prophylaxis of invasive fungal infections in bone marrow transplant recipientsQ72312612
Role of granulocyte-macrophage colony-stimulating factor as adjuvant therapy for fungal infection in patients with cancerQ72675254
Clinical applicability of the new EORTC/MSG classification for invasive pulmonary aspergillosis in patients with hematological malignancies and autopsy-confirmed invasive aspergillosisQ73037373
A randomized controlled trial of itraconazole versus fluconazole for the prevention of fungal infections in patients with haematological malignancies. U.K. Multicentre Antifungal Prophylaxis Study GroupQ73165218
Increasing volume and changing characteristics of invasive pulmonary aspergillosis on sequential thoracic computed tomography scans in patients with neutropeniaQ73336907
Itraconazole trough concentrations in antifungal prophylaxis with six different dosing regimens using hydroxypropyl-beta-cyclodextrin oral solution or coated-pellet capsulesQ73460720
Tolerance and efficacy of Amphotericin B inhalations for prevention of invasive pulmonary aspergillosis in haematological patientsQ73521812
Fungal infection of burn wounds in patients with open and occlusive treatment methodsQ73741246
Treatment of neutropenia-related fungal infections with granulocyte colony-stimulating factor-elicited white blood cell transfusions: a pilot studyQ73767268
Comparison of premortem clinical diagnoses in critically iII patients and subsequent autopsy findingsQ73892686
Surgical management of invasive pulmonary aspergillosis in neutropenic patientsQ73916229
Combination antifungal therapy for invasive aspergillosisQ45096994
Postmortem analysis of invasive aspergillosis in a tertiary care hospitalQ45143296
Fluconazole versus itraconazole for antifungal prophylaxis in neutropenic patients with haematological malignancies: a meta-analysis of randomised-controlled trialsQ45168346
Efficacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant of conventional antifungal therapyQ45172488
Aspergillus antigen in serum, urine and bronchoalveolar lavage specimens of neutropenic patients in relation to clinical outcomeQ45268727
Prophylactic and interventional granulocyte transfusions in patients with haematological malignancies and life-threatening infections during neutropeniaQ45282734
Treatment of invasive aspergillosis with itraconazoleQ46380526
Amphotericin B lipid complex in the management of invasive aspergillosis in immunocompromised patientsQ46421810
Study of renal safety in amphotericin B lipid complex-treated patientsQ46421821
Lipid formulations of amphotericin B: clinical efficacy and toxicitiesQ46460941
Choosing a study population for the evaluation of antifungal prophylaxisQ46486680
Antifungal therapy decreases sensitivity of the Aspergillus galactomannan enzyme immunoassayQ46503389
Usefulness of liposomal amphotericin B for the prophylaxis of fungal infection in solid organ transplant recipientsQ46508942
Evaluation of serum sandwich enzyme-linked immunosorbent assay for circulating galactomannan during caspofungin therapy: results from the caspofungin invasive aspergillosis studyQ46529531
Improved outcome in central nervous system aspergillosis, using voriconazole treatmentQ46585075
Strategy of following voriconazole versus amphotericin B therapy with other licensed antifungal therapy for primary treatment of invasive aspergillosis: impact of other therapies on outcomeQ46758158
An open-label randomized trial comparing itraconazole oral solution with fluconazole oral solution for primary prophylaxis of fungal infections in patients with haematological malignancy and profound neutropenia.Q46844044
The use of stimulated granulocyte transfusions to prevent recurrence of past severe infections after allogeneic stem cell transplantationQ47612248
Intracranial aspergillosis in children successfully treated with antifungal therapy and surgical intervention.Q48602772
Impact of previous aspergillosis on the outcome of bone marrow transplantationQ49172509
Bloodstream infections in organ transplant recipients receiving alemtuzumab: no evidence of occurrence of organisms typically associated with profound T cell depletionQ50084520
Aerosol deposition of lipid complex amphotericin-B (Abelcet) in lung transplant recipients.Q51116991
Micafungin (FK463), alone or in combination with other systemic antifungal agents, for the treatment of acute invasive aspergillosis.Q51187346
Opportunistic mycelial fungal infections in organ transplant recipients: emerging importance of non-Aspergillus mycelial fungi.Q51190403
Clinical evaluation of a polymerase chain reaction assay to detect Aspergillus species in bronchoalveolar lavage samples of neutropenic patients.Q51191494
Relationship between environmental fungal contamination and the incidence of invasive aspergillosis in haematology patients.Q51192022
Screening for circulating galactomannan as a noninvasive diagnostic tool for invasive aspergillosis in prolonged neutropenic patients and stem cell transplantation recipients: a prospective validation.Q51192216
Efficacy of prevention by high-efficiency particulate air filtration or laminar airflow against Aspergillus airborne contamination during hospital renovation.Q51193013
Airborne fungal spore monitoring in a protective environment during hospital construction, and correlation with an outbreak of invasive aspergillosis.Q51195391
Invasive aspergillosis in patients with acquired immunodeficiency syndrome: report of 33 cases. French Cooperative Study Group on Aspergillosis in AIDS.Q51195851
Differences in beta-glucan levels in culture supernatants of a variety of fungi.Q51201410
Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors.Q51700168
Pneumonia in febrile neutropenic patients and in bone marrow and blood stem-cell transplant recipients: use of high-resolution computed tomography.Q52222221
Impact of air filtration on nosocomial Aspergillus infections. Unique risk of bone marrow transplant recipients.Q52588180
Early detection of aspergillus infection after allogeneic stem cell transplantation by polymerase chain reaction screening.Q52922198
An EORTC international multicenter randomized trial (EORTC number 19923) comparing two dosages of liposomal amphotericin B for treatment of invasive aspergillosis.Q53349495
Non-comparative evaluation of the safety of aerosolized amphotericin B lipid complex in patients undergoing allogeneic hematopoietic stem cell transplantation.Q53626853
Amphotericin B lipid complex for invasive fungal infections: analysis of safety and efficacy in 556 cases.Q53950594
Liposomal amphotericin (AmBisome) in the prophylaxis of fungal infections in neutropenic patients: a randomised, double-blind, placebo-controlled study.Q53999286
Prophylactic action of oral fluconazole against fungal infection in neutropenic patients. A meta-analysis of 16 randomized, controlled trials.Q54034991
Pathogenic Aspergillus species recovered from a hospital water system: a 3-year prospective study.Q54251450
Prophylactic intravenous amphotericin B in neutropenic autologous bone marrow transplant recipientsQ54270865
P433issue11
P921main subjectaspergillosisQ259626
invasive aspergillosisQ3625278
P304page(s)1567-1601
P577publication date2007-01-01
P1433published inDrugsQ3040094
P1476titleInvasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients
P478volume67

Reverse relations

cites work (P2860)
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