scholarly article | Q13442814 |
P2093 | author name string | James D Baleja | |
Gary E Gilbert | |||
Valerie A Novakovic | |||
Philip J Fay | |||
Hironao Wakabayashi | |||
David B Cullinan | |||
P2860 | cites work | Structure and topography of the membrane-binding C2 domain of factor VIII in the presence of dodecylphosphocholine micelles | Q24530891 |
Crystal structures of the membrane-binding C2 domain of human coagulation factor V | Q27620579 | ||
Structure of the C2 domain of human factor VIII at 1.5 A resolution | Q27620583 | ||
Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII | Q27632668 | ||
The tertiary structure and domain organization of coagulation factor VIII | Q27648918 | ||
Crystal structure of lactadherin C2 domain at 1.7A resolution with mutational and computational analyses of its membrane-binding motif | Q27649435 | ||
Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex | Q27650288 | ||
Trp2313-His2315 of Factor VIII C2 Domain Is Involved in Membrane Binding: STRUCTURE OF A COMPLEX BETWEEN THE C2 DOMAIN AND AN INHIBITOR OF MEMBRANE BINDING | Q27659074 | ||
Membrane-binding peptide from the C2 domain of factor VIII forms an amphipathic structure as determined by NMR spectroscopy | Q27730428 | ||
Mechanism and kinetics of factor VIII inactivation: study with an IgG4 monoclonal antibody derived from a hemophilia A patient with inhibitor | Q28115761 | ||
Molecular cloning of a cDNA encoding human antihaemophilic factor | Q28268498 | ||
Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine | Q28299233 | ||
Binding of human factor VIII to phospholipid vesicles | Q28630342 | ||
Activation of factor VIII by thrombin increases its affinity for binding to synthetic phospholipid membranes and activated platelets | Q28631517 | ||
cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences | Q33790760 | ||
Factor VIII lacking the C2 domain retains cofactor activity in vitro | Q34055694 | ||
A simple method for the preparation of homogeneous phospholipid vesicles | Q34405356 | ||
Antihuman factor VIII C2 domain antibodies in hemophilia A mice recognize a functionally complex continuous spectrum of epitopes dominated by inhibitors of factor VIII activation | Q36447889 | ||
Coagulation factors V and VIII and ceruloplasmin constitute a family of structurally related proteins | Q37576606 | ||
The sequence Glu1811-Lys1818 of human blood coagulation factor VIII comprises a binding site for activated factor IX. | Q38362540 | ||
Mutation of the surface-exposed amino acid Trp to Ala in the FVIII C2 domain results in defective secretion of the otherwise functional protein | Q40555265 | ||
Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity | Q43290531 | ||
Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs | Q43792218 | ||
Deletion analysis of recombinant human factor V. Evidence for a phosphatidylserine binding site in the second C-type domain | Q44106754 | ||
The Gla domain of factor IXa binds to factor VIIIa in the tenase complex | Q44463045 | ||
Residues 110-126 in the A1 domain of factor VIII contain a Ca2+ binding site required for cofactor activity | Q44727130 | ||
Contribution of factor VIIIa A2 and A3-C1-C2 subunits to the affinity for factor IXa in factor Xase | Q44861371 | ||
Disruption of protein-membrane binding and identification of small-molecule inhibitors of coagulation factor VIII. | Q45110663 | ||
Identification of functionally important amino acid residues within the C2-domain of human factor V using alanine-scanning mutagenesis | Q45865459 | ||
Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities | Q45878659 | ||
The factor VIIIa C2 domain (residues 2228-2240) interacts with the factor IXa Gla domain in the factor Xase complex | Q46220531 | ||
Role of the C2 domain of factor VIIIa in the assembly of factor-X activating complex on the platelet membrane | Q46756615 | ||
Characterization of the human factor VIII gene | Q48385931 | ||
The preparation and phospholipid binding property of the C2 domain of human factor VIII | Q50331339 | ||
Specificity of phosphatidylserine-containing membrane binding sites for factor VIII. Studies with model membranes supported by glass microspheres (lipospheres). | Q52416182 | ||
Factor VIII procoagulant protein interacts with phospholipid vesicles via its 80 kDa light chain | Q67245901 | ||
The binding of factor Va to phospholipid vesicles | Q67919544 | ||
The association of human coagulation factors VIII, IXa and X with phospholipid vesicles involves both electrostatic and hydrophobic interactions | Q68028824 | ||
Membrane binding kinetics of factor VIII indicate a complex binding process | Q70660197 | ||
Localization of a factor X interactive site in the A1 subunit of factor VIIIa | Q71985134 | ||
A factor VIII neutralizing monoclonal antibody and a human inhibitor alloantibody recognizing epitopes in the C2 domain inhibit factor VIII binding to von Willebrand factor and to phosphatidylserine | Q72076617 | ||
Factor VIIIa A2 subunit residues 558-565 represent a factor IXa interactive site | Q72108212 | ||
Specific membrane binding of factor VIII is mediated by O-phospho-L-serine, a moiety of phosphatidylserine | Q72927413 | ||
Amphipathic helices support function of blood coagulation factor IXa | Q73015517 | ||
Functional analyses of two cellular binding domains of bovine lactadherin | Q73815267 | ||
Inhibitory anti-factor V antibodies bind to the factor V C2 domain and are associated with hemorrhagic manifestations | Q74576919 | ||
Phospholipid-binding domain of factor VIII is involved in endothelial cell-mediated activation of factor X by factor IXa | Q77743425 | ||
Anticoagulant effects of a synthetic peptide containing residues Thr-2253-Gln-2270 within factor VIII C2 domain that selectively inhibits factor Xa-catalysed factor VIII activation | Q77748060 | ||
Immunodominant T-cell epitopes in the factor VIII C2 domain are located within an inhibitory antibody binding site | Q80534658 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P1104 | number of pages | 10 | |
P304 | page(s) | 187-196 | |
P577 | publication date | 2011-04-01 | |
P1433 | published in | Biochemical Journal | Q864221 |
P1476 | title | Membrane-binding properties of the Factor VIII C2 domain | |
P478 | volume | 435 |
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Q44781327 | Backbone resonance assignments of the C2 domain of coagulation factor VIII. |
Q30153398 | Changes in the Factor VIII C2 domain upon membrane binding determined by hydrogen-deuterium exchange MS. |
Q30384710 | Dimeric Organization of Blood Coagulation Factor VIII bound to Lipid Nanotubes. |
Q27677560 | Domain organization of membrane-bound factor VIII. |
Q35688388 | In situ quantification of protein binding to the plasma membrane. |
Q37915629 | Localized amyloids important in diseases outside the brain--lessons from the islets of Langerhans and the thoracic aorta |
Q41316755 | Membrane Interaction of the Factor VIIIa Discoidin Domains in Atomistic Detail |
Q42425297 | Molecular orientation of factor VIIIa on the phospholipid membrane surface determined by fluorescence resonance energy transfer |
Q42581565 | Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine |
Q30353558 | Replacing the factor VIII C1 domain with a second C2 domain reduces factor VIII stability and affinity for factor IXa |
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