| scholarly article | Q13442814 |
| P2093 | author name string | D M Coen | |
| L K Leslie | |||
| H E Fleming | |||
| M J Retondo | |||
| P2860 | cites work | Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine | Q24561391 |
| Trisodium Phosphonoformate, a New Antiviral Compound | Q28321928 | ||
| (E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent | Q28322607 | ||
| Effect of combinations of acyclovir with vidarabine or its 5'-monophosphate on herpes simplex viruses in cell culture and in mice | Q28365880 | ||
| A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2 | Q28366181 | ||
| Unique spectrum of activity of 9-[(1,3-dihydroxy-2-propoxy)methyl]-guanine against herpesviruses in vitro and its mode of action against herpes simplex virus type 1 | Q28366232 | ||
| 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication | Q28366245 | ||
| Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine | Q28366255 | ||
| On the mechanism of selective inhibition of herpesvirus replication by (E)-5-(2-bromovinyl)-2'-deoxyuridine | Q35358460 | ||
| Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin | Q35568390 | ||
| Resistance of herpes simplex virus to 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine: physical mapping of drug synergism within the viral DNA polymerase locus | Q36252289 | ||
| Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1 | Q36365046 | ||
| Resistance of herpes simplex virus to acycloguanosine: role of viral thymidine kinase and DNA polymerase loci | Q36365079 | ||
| Growth Inhibition by Acycloguanosine of Herpesviruses Isolated from Human Infections | Q36480504 | ||
| DNA synthesis and DNA polymerase activity of herpes simplex virus type 1 temperature-sensitive mutants | Q36539315 | ||
| Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus | Q36911158 | ||
| Transcriptional and genetic analyses of the herpes simplex virus type 1 genome: coordinates 0.29 to 0.45 | Q36913463 | ||
| Cooperative effects between two acyclovir resistance loci in herpes simplex virus | Q36917582 | ||
| Acyclovir-resistant mutants of herpes simplex virus type 1 express altered DNA polymerase or reduced acyclovir phosphorylating activities | Q36935945 | ||
| Mutations in the herpes simplex virus DNA polymerase gene can confer resistance to 9-beta-D-arabinofuranosyladenine | Q36939346 | ||
| Genetics of resistance to phosphonoacetic acid in strain KOS of herpes simplex virus type 1 | Q37506935 | ||
| Metabolism of acyclovir in virus-infected and uninfected cells | Q39855907 | ||
| Mutants of Herpes Simplex Virus Types 1 and 2 that are Resistant to Phosphonoacetic Acid Induce Altered DNA Polymerase Activities in Infected Cells | Q39985897 | ||
| Identification of the herpes simplex virus DNA polymerase gene | Q40108235 | ||
| Physical mapping of paar mutations of herpes simplex virus type 1 and type 2 by intertypic marker rescue | Q40254451 | ||
| Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin | Q40493059 | ||
| Characteristics of Herpesvirus Mutants Resistant to Phosphonoformate and Phosphonoacetate | Q40620526 | ||
| Susceptibility of phosphonoformic acid-resistant herpes simplex virus variants to arabinosylnucleosides and aphidicolin | Q42026259 | ||
| The incorporation of 5-iodo-5′-amino-2′,5′-dideoxyuridine and 5-iodo-2′-deoxyuridine into herpes simplex virus DNA. Relationship between antiviral activity and effects on DNA structure | Q42244562 | ||
| Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U | Q42929717 | ||
| A comparison of the antiviral agents 2′-nor-2′-deoxyguanosine and acyclovir: Uptake and phosphorylation in tissue culture and kinetics of in vitro inhibition of viral and cellular DNA polymerases by their respective triphosphates | Q43522131 | ||
| Nucleoside analogues with clinical potential in antivirus chemotherapy. The effect of several thymidine and 2'-deoxycytidine analogue 5'-triphosphates on purified human (alpha, beta) and herpes simplex virus (types 1, 2) DNA polymerases | Q44546875 | ||
| Generation of genetic diversity in herpes simplex virus: An antimutator phenotype maps to the DNA polymerase locus | Q45797089 | ||
| Interaction of herpes simplex virus-induced DNA polymerase with 9-(1,3-dihydroxy-2-propoxymethyl)guanine triphosphate. | Q45797195 | ||
| Resistance of herpes simplex virus to adenine arabinoside and E-5-(2-bromovinyl)-2'-deoxyuridine: a physical analysis | Q45799905 | ||
| The Sensitivity of Acyclovir-Resistant Mutants of Herpes Simplex Virus to Other Antiviral Drugs | Q45802357 | ||
| Resistance of herpes simplex virus to acycloguanosine—genetic and physical analysis | Q45803248 | ||
| Properties of Herpes simplex virus type 1 and type 2 DNA polymerase | Q45803333 | ||
| Physical and genetic analysis of the herpes simplex virus DNA polymerase locus | Q45803539 | ||
| Single mutations at many sites within the DNA polymerase locus of herpes simplex viruses can confer hypersensitivity to aphidicolin and resistance to phosphonoacetic acid. | Q54484986 | ||
| Differential inhibition of mammalian DNA polymerases alpha, beta and gamma and herpes simplex virus-induced DNA polymerase by the 5'-triphosphates of arabinosyladenine and arabinosylcytosine | Q66703120 | ||
| Spectrum of human cytomegalovirus complement-fixing antigens | Q68571965 | ||
| Drug therapy. Treatment of herpesvirus infections | Q70166059 | ||
| Genetic analysis of temperature-sensitive mutants of HSV-1: The combined use of complementation and physical mapping for cistron assignment | Q70178006 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 12 | |
| P304 | page(s) | 477-488 | |
| P577 | publication date | 1985-02-01 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus | |
| P478 | volume | 53 |
| Q36792302 | A conserved open reading frame that overlaps the herpes simplex virus thymidine kinase gene is important for viral growth in cell culture |
| Q24628878 | A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate |
| Q35462273 | A net +1 frameshift permits synthesis of thymidine kinase from a drug-resistant herpes simplex virus mutant |
| Q35807437 | A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives |
| Q43934776 | A role for MAP kinase in the antitumor activity of a nucleoside analog |
| Q40131420 | A single-base change within the DNA polymerase locus of herpes simplex virus type 2 can confer resistance to aphidicolin |
| Q35889767 | A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus |
| Q39642251 | Accumulation of viral transcripts and DNA during establishment of latency by herpes simplex virus. |
| Q39652859 | Application of real-time PCR for determination of antiviral drug susceptibility of herpes simplex virus |
| Q45782098 | Clinical and histopathologic study of varicella zoster virus retinitis in patients with the acquired immunodeficiency syndrome. |
| Q28359879 | Efficacies of antiherpesvirus nucleosides against two strains of herpes simplex virus type 1 in Vero and human embryo lung fibroblast cells |
| Q36795936 | Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition |
| Q36830830 | Examination of the roles of transcription factor Sp1-binding sites and an octamer motif in trans induction of the herpes simplex virus thymidine kinase gene |
| Q45854779 | Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant |
| Q35947601 | Expression of extremely low levels of thymidine kinase from an acyclovir-resistant herpes simplex virus mutant supports reactivation from latently infected mouse trigeminal ganglia |
| Q40044170 | Functional analysis of the herpes simplex virus UL42 protein. |
| Q37880547 | Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections |
| Q36650383 | Genetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain. |
| Q36680349 | Genetic characterization of the vaccinia virus DNA polymerase: identification of point mutations conferring altered drug sensitivities and reduced fidelity |
| Q64238762 | Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs |
| Q39798154 | Herpes simplex virus 1 immediate-early and early gene expression during reactivation from latency under conditions that prevent infectious virus production |
| Q39316080 | Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity. |
| Q35345912 | Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir |
| Q24519013 | Human cytomegalovirus mutant with sequence-dependent resistance to the phosphorothioate oligonucleotide fomivirsen (ISIS 2922) |
| Q33783612 | Human thymidine kinase can functionally replace herpes simplex virus type 1 thymidine kinase for viral replication in mouse sensory ganglia and reactivation from latency upon explant |
| Q34552631 | ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cells |
| Q33646854 | Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition |
| Q34349368 | Identification, localization, and regulation of expression of the UL24 protein of herpes simplex virus type 1. |
| Q40117537 | In vitro mutagenesis of the herpes simplex virus type 1 DNA polymerase gene results in altered drug sensitivity of the enzyme. |
| Q33850767 | Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments. |
| Q45406414 | Involvement of UL24 in herpes-simplex-virus-1-induced dispersal of nucleolin |
| Q36886967 | Isolation and characterization of phosphonoacetic acid-resistant mutants of human cytomegalovirus. |
| Q34593731 | MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs |
| Q35653248 | Mutation within the herpes simplex virus DNA polymerase gene conferring resistance to (R)-9-(3,4-dihydroxybutyl)guanine |
| Q37560704 | Mutations Inactivating Herpes Simplex Virus 1 MicroRNA miR-H2 Do Not Detectably Increase ICP0 Gene Expression in Infected Cultured Cells or Mouse Trigeminal Ganglia |
| Q34338858 | Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus |
| Q33826615 | Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2. |
| Q36883978 | Pathogenicity of herpes simplex virus mutants containing drug resistance mutations in the viral DNA polymerase gene |
| Q45757602 | Penciclovir and pathogenesis phenotypes of drug-resistant Herpes simplex virus mutants |
| Q24806094 | Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection |
| Q40062049 | Point mutations in the DNA polymerase gene of human cytomegalovirus that result in resistance to antiviral agents |
| Q40640573 | Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site |
| Q34648394 | Prediction and identification of herpes simplex virus 1-encoded microRNAs |
| Q35833656 | Quantification of transcripts from the ICP4 and thymidine kinase genes in mouse ganglia latently infected with herpes simplex virus |
| Q37211704 | Rapid detection of cytomegalovirus in clinical specimens by using biotinylated DNA probes and analysis of cross-reactivity with herpes simplex virus |
| Q35855478 | Reactivation of thymidine kinase-defective herpes simplex virus is enhanced by nucleoside |
| Q39683254 | Replication fidelity of the supF gene integrated in the thymidine kinase locus of herpes simplex virus type 1. |
| Q34149904 | Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management |
| Q37538128 | Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain. |
| Q39174061 | Significance of resistance of herpes simplex virus to acyclovir. |
| Q36784195 | Structure-function studies of the herpes simplex virus type 1 DNA polymerase. |
| Q33739521 | Susceptibility to other antiherpes drugs of pathogenic variants of herpes simplex virus selected for resistance to acyclovir |
| Q45784444 | Synergistic effects on ganglionic herpes simplex virus infections by mutations or drugs that inhibit the viral polymerase and thymidine kinase |
| Q34812506 | The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases |
| Q36639684 | The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication. |
| Q39580830 | The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation |
| Q33864322 | Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate. |
| Q42425029 | Virucidal activity of a GT-rich oligonucleotide against herpes simplex virus mediated by glycoprotein B |
| Q27314873 | Visualization of mouse neuronal ganglia infected by Herpes Simplex Virus 1 (HSV-1) using multimodal non-linear optical microscopy |
| Q41676922 | What clinicians need to know about antiviral drugs and viral resistance |
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