Exogenous insulin-like growth factor 1 enhances thymopoiesis predominantly through thymic epithelial cell expansion

scientific article published on 24 July 2008

Exogenous insulin-like growth factor 1 enhances thymopoiesis predominantly through thymic epithelial cell expansion is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2008-04-149435
P932PMC publication ID2556619
P698PubMed publication ID18658030
P5875ResearchGate publication ID51431073

P2093author name stringDavid Howe
Veena Kapoor
Ronald E Gress
Yu-Waye Chu
Susan Garfield
Baishakhi Choudhury
Sabrina Schmitz
William Telford
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IGF-1 receptor regulates lifespan and resistance to oxidative stress in miceQ29616382
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Insulin-like growth factor-1 stimulation of lymphopoiesisQ34169714
The insulin-like growth factor system and cancerQ34200058
Lymphostromal interactions in thymic development and functionQ34572126
Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cellsQ35804466
Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation.Q35849623
Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilizationQ36027708
T cell immune reconstitution following lymphodepletion.Q36334023
Cyclical mobilization and gated importation of thymocyte progenitors in the adult mouse: evidence for a thymus-bone marrow feedback loopQ36382723
Journey through the thymus: stromal guides for T-cell development and selectionQ36402237
A central role for thymic emigrants in peripheral T cell homeostasisQ36433740
Mechanisms of disease: metabolic effects of growth hormone and insulin-like growth factor 1.Q36742060
Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose fromQ36854590
Thymic involution: implications for self-toleranceQ36944585
Keratinocyte growth factor receptorsQ36954792
Generating intrathymic microenvironments to establish T-cell tolerance.Q36997113
Pituitary hormones modulate cell-cell interactions between thymocytes and thymic epithelial cellsQ41108039
The somatogenic hormones and insulin-like growth factor-1: stimulators of lymphopoiesis and immune functionQ41430668
Murine macrophages express abundant insulin-like growth factor-I class I Ea and Eb transcriptsQ41515399
Growth-promoting effects of insulin-like growth factor-1 (IGF-1) on hematopoietic cells: overexpression of introduced IGF-1 receptor abrogates interleukin-3 dependency of murine factor-dependent cells by a ligand-dependent mechanismQ41669915
Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activityQ43513983
Scheduled kinetics of cell proliferation and phenotypic changes during immature thymocyte generationQ43760317
Insulin-like growth factor-1 activates Akt and Jun N-terminal kinases (JNKs) in promoting the survival of T lymphocytesQ44235062
IGF-1 down-regulates IFN-gamma R2 chain surface expression and desensitizes IFN-gamma/STAT-1 signaling in human T lymphocytes.Q45136735
Effects of insulin-like growth factor administration and bone marrow transplantation on thymopoiesis in aged miceQ46844638
Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function.Q47637782
Insulin growth factor-I inhibits apoptosis in hematopoietic progenitor cells. Implications in thymic agingQ47966533
Expression of insulin-like growth factor I stimulates normal somatic growth in growth hormone-deficient transgenic miceQ48901708
Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal ThymusQ51016385
Hematopoietic stem cell dose correlates with the speed of immune reconstitution after stem cell transplantation.Q51027004
Type I insulin-like growth factor receptor expression in different developmental stages of human thymocytes.Q52205267
Involvement of CCR9 at multiple stages of adult T lymphopoiesisQ60042098
Sequential events in thymocyte differentiation and thymus regeneration revealed by a combination of bromodeoxyuridine DNA labeling and antimitotic drug treatmentQ68092912
Growth hormone and insulin-like growth factor-I stimulate hormonal function and proliferation of thymic epithelial cellsQ68185115
Expression of growth hormone receptors in murine lymphoid cells analyzed by flow cytofluorometryQ71033132
The conveyor belt model for intrathymic T-cell migrationQ71534222
Lymphoid and myeloid differentiation of single human CD34+, HLA-DR+, CD38- hematopoietic stem cellsQ71613357
Insulin-like growth factor I is essential for postnatal growth in response to growth hormoneQ73120944
The insulin-like growth factor system in normal and malignant hematopoietic cellsQ73205605
Involvement of insulin-like growth factors in early T cell development: a study using fetal thymic organ culturesQ73500728
Insulin-like growth factor-I enhances lymphoid and myeloid reconstitution after allogeneic bone marrow transplantationQ73582357
Regulation and kinetics of premigrant thymocyte expansionQ73603812
The insulin-like growth factor-I receptor is regulated by CD28 and protects activated T cells from apoptosisQ73666607
Expansion of mature thymocyte subsets before emigration to the peripheryQ73873478
Early effects of insulin-like growth factor-1 in activated human T lymphocytesQ74330941
Selective thymus settling regulated by cytokine and chemokine receptorsQ79717946
Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1Q81725600
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectpreproinsulinQ7240673
P304page(s)2836-2846
P577publication date2008-07-24
P1433published inBloodQ885070
P1476titleExogenous insulin-like growth factor 1 enhances thymopoiesis predominantly through thymic epithelial cell expansion
P478volume112

Reverse relations

cites work (P2860)
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