| scholarly article | Q13442814 |
| P356 | DOI | 10.1111/IMR.12404 |
| P698 | PubMed publication ID | 27088904 |
| P2093 | author name string | Izumi Ohigashi | |
| Yousuke Takahama | |||
| Mina Kozai | |||
| P2860 | cites work | Adult thymic epithelium contains nonsenescent label-retaining cells. | Q51164735 |
| Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. | Q52010433 | ||
| Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. | Q52014296 | ||
| Homing of immature thymocytes to the subcapsular microenvironment within the thymus is not an absolute requirement for T cell development. | Q52086717 | ||
| NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. | Q52093900 | ||
| Two genetically separable steps in the differentiation of thymic epithelium. | Q52201522 | ||
| Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis. | Q53174108 | ||
| Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t. | Q53255947 | ||
| The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. | Q53453365 | ||
| Coordination between CCR7- and CCR9-mediated chemokine signals in prevascular fetal thymus colonization. | Q53614503 | ||
| Features of medullary thymic epithelium implicate postnatal development in maintaining epithelial heterogeneity and tissue-restricted antigen expression. | Q53624774 | ||
| Thymic nurse cells--Ia-bearing epithelium involved in T-lymphocyte differentiation? | Q54659497 | ||
| Medullary thymic epithelial stem cells maintain a functional thymus to ensure lifelong central T cell tolerance. | Q55058749 | ||
| Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance | Q56701390 | ||
| Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex | Q59071991 | ||
| Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence | Q21136364 | ||
| Cloning of a novel MHC-encoded serine peptidase highly expressed by cortical epithelial cells of the thymus | Q22010693 | ||
| New member of the winged-helix protein family disrupted in mouse and rat nude mutations | Q24308068 | ||
| Interleukin-22 drives endogenous thymic regeneration in mice | Q24595764 | ||
| In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker | Q24633015 | ||
| The basics of epithelial-mesenchymal transition | Q24652992 | ||
| Regulation of CD8+ T cell development by thymus-specific proteasomes | Q28116400 | ||
| Dependence of self-tolerance on TRAF6-directed development of thymic stroma | Q28590193 | ||
| Expression of relB is required for the development of thymic medulla and dendritic cells | Q28594949 | ||
| Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus | Q28613227 | ||
| Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner | Q28755731 | ||
| Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see) | Q29391777 | ||
| The role of autophagy during the early neonatal starvation period | Q29547489 | ||
| Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation | Q29614736 | ||
| Thymic fatness and approaches to enhance thymopoietic fitness in aging | Q33349488 | ||
| Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy | Q33648539 | ||
| CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus | Q33722636 | ||
| Questionable thymic nurse cell | Q34010379 | ||
| Adult thymus contains FoxN1(-) epithelial stem cells that are bipotent for medullary and cortical thymic epithelial lineages | Q34106631 | ||
| Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family | Q34317095 | ||
| Ancestral founder mutation of the nude (FOXN1) gene in congenital severe combined immunodeficiency associated with alopecia in southern Italy population | Q34324916 | ||
| The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene | Q34389136 | ||
| Regeneration of the aged thymus by a single transcription factor. | Q34414351 | ||
| Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire | Q34501485 | ||
| Lymphostromal interactions in thymic development and function | Q34572126 | ||
| Serial progression of cortical and medullary thymic epithelial microenvironments | Q34617656 | ||
| Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice | Q34876029 | ||
| Role of thymic organ structure and stromal composition in steady-state postnatal T-cell production | Q35005841 | ||
| Thymic nurse cells: a microenvironment for thymocyte development and selection | Q35086645 | ||
| Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells | Q35585931 | ||
| The thymic cortical epithelium determines the TCR repertoire of IL-17-producing γδT cells. | Q35595498 | ||
| Developing a new paradigm for thymus organogenesis. | Q35730814 | ||
| A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene | Q35785861 | ||
| Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells | Q35804466 | ||
| Regenerative capacity of adult cortical thymic epithelial cells | Q35807736 | ||
| A silent chemokine receptor regulates steady-state leukocyte homing in vivo | Q35850200 | ||
| Persistent degenerative changes in thymic organ function revealed by an inducible model of organ regrowth. | Q35861067 | ||
| Adult hepatocytes are generated by self-duplication rather than stem cell differentiation. | Q35861861 | ||
| Sex hormones have pervasive effects on thymic epithelial cells. | Q35926133 | ||
| Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium | Q36011240 | ||
| Thymoproteasomes produce unique peptide motifs for positive selection of CD8(+) T cells | Q36018570 | ||
| Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire | Q36229072 | ||
| Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment | Q36322501 | ||
| Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor beta | Q36363101 | ||
| Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development | Q36369382 | ||
| Cathepsin L regulates CD4+ T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands | Q36370268 | ||
| Journey through the thymus: stromal guides for T-cell development and selection | Q36402237 | ||
| Thymic nurse cells provide microenvironment for secondary T cell receptor α rearrangement in cortical thymocytes. | Q36483791 | ||
| Metabolic Damage and Premature Thymus Aging Caused by Stromal Catalase Deficiency | Q36701272 | ||
| TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells | Q36737068 | ||
| The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development | Q36750060 | ||
| Thymoproteasome subunit-β5T generates peptide-MHC complexes specialized for positive selection | Q36799097 | ||
| Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from | Q36854590 | ||
| Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression | Q36907931 | ||
| Exogenous insulin-like growth factor 1 enhances thymopoiesis predominantly through thymic epithelial cell expansion | Q36915906 | ||
| Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells | Q36932226 | ||
| Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. | Q36946535 | ||
| Characterization of the thymic IL-7 niche in vivo. | Q37083552 | ||
| Thymus organogenesis | Q37096077 | ||
| Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity | Q37119813 | ||
| Thymus development and function | Q37134900 | ||
| Thymic involution and immune reconstitution. | Q37361275 | ||
| The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence | Q37444372 | ||
| The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors. | Q37552560 | ||
| An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells | Q37627734 | ||
| Antigen presentation in the thymus for positive selection and central tolerance induction | Q37638193 | ||
| Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors | Q37650757 | ||
| β5t-containing thymoproteasome: specific expression in thymic cortical epithelial cells and role in positive selection of CD8+ T cells | Q37979610 | ||
| Thymic epithelial cells: working class heroes for T cell development and repertoire selection | Q38010575 | ||
| Thymus involution and regeneration: two sides of the same coin? | Q38139859 | ||
| Positive-selection-inducing self-peptides displayed by cortical thymic epithelial cells | Q38319419 | ||
| Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation. | Q38469675 | ||
| Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4. | Q39758257 | ||
| Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro. | Q40683787 | ||
| How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway | Q41020969 | ||
| Thymic nurse cells. Lymphoepithelial cell complexes in murine thymuses: morphological and serological characterization | Q41612029 | ||
| Thymic nurse cells exclusively bind and internalize CD4+CD8+ thymocytes | Q41631888 | ||
| The thymus-specific serine protease TSSP/PRSS16 is crucial for the antitumoral role of CD4(+) T cells | Q41646253 | ||
| Selective elimination of double-positive immature thymocytes by a thymic epithelial cell line | Q41756375 | ||
| RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla | Q41868543 | ||
| Delta-like 4 is indispensable in thymic environment specific for T cell development | Q42277361 | ||
| Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution | Q42780735 | ||
| Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice. | Q42809389 | ||
| Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors. | Q42945036 | ||
| CCR7 signals are essential for cortex-medulla migration of developing thymocytes. | Q42971212 | ||
| CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus. | Q43434964 | ||
| CCX-CKR deficiency alters thymic stroma impairing thymocyte development and promoting autoimmunity | Q43453611 | ||
| Regeneration of the adult thymus is preceded by the expansion of K5+K8+ epithelial cell progenitors and by increased expression of Trp63, cMyc and Tcf3 transcription factors in the thymic stroma | Q43776627 | ||
| Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium | Q44781101 | ||
| Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes | Q46089880 | ||
| Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors | Q48070901 | ||
| Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice. | Q50493740 | ||
| Multilineage potential and self-renewal define an epithelial progenitor cell population in the adult thymus. | Q50640787 | ||
| Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells. | Q50766532 | ||
| Thymocyte selection regulates the homeostasis of IL-7-expressing thymic cortical epithelial cells in vivo. | Q50883531 | ||
| Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus | Q51016385 | ||
| Lymphotoxin β receptor regulates the development of CCL21-expressing subset of postnatal medullary thymic epithelial cells. | Q51068690 | ||
| Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes. | Q51127244 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 10-22 | |
| P577 | publication date | 2016-05-01 | |
| P1433 | published in | Immunological Reviews | Q15724582 |
| P1476 | title | Development and developmental potential of cortical thymic epithelial cells | |
| P478 | volume | 271 |
| Q89046279 | A Single-Cell Transcriptomic Atlas of Thymus Organogenesis Resolves Cell Types and Developmental Maturation |
| Q47663392 | A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice |
| Q51140178 | Construction of Thymus Organoids from Decellularized Thymus Scaffolds. |
| Q47325254 | Dissecting and modeling the emergent murine TEC compartment during ontogeny. |
| Q37698767 | Epithelial LTβR signaling controls the population size of the progenitors of medullary thymic epithelial cells in neonatal mice |
| Q50519670 | Form follows function, function follows form: how lymphoid tissues enable and constrain immune reactions. |
| Q39187317 | Generation of diversity in thymic epithelial cells. |
| Q39328219 | IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes |
| Q90126173 | NF-κB-inducing kinase contributes to normal development of cortical thymic epithelial cells: its possible role in shaping a proper T cell repertoire |
| Q33894832 | Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell Development |
| Q46008364 | Revisiting the Road Map of Medullary Thymic Epithelial Cell Differentiation. |
| Q39185546 | Soluble antigens from the neurotropic pathogen Angiostrongylus cantonensis directly induce thymus atrophy in a mouse model |
| Q91718584 | Thymic epithelial cell heterogeneity: TEC by TEC |
| Q60921146 | Thymic expression of IL-4 and IL-15 after systemic inflammatory or infectious Th1 disease processes induce the acquisition of "innate" characteristics during CD8+ T cell development |
| Q33729251 | Thymic homing of activated CD4+ T cells induces degeneration of the thymic epithelium through excessive RANK signaling |
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