| scholarly article | Q13442814 |
| P50 | author | Chris Goodnow | Q5106685 |
| Adrian Liston | Q37384388 | ||
| Daniel H Gray | Q48358835 | ||
| Andrew M Lew | Q56486071 | ||
| P2093 | author name string | Richard L Boyd | |
| Natalie Seach | |||
| Tomoo Ueno | |||
| Morag K Milton | |||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 3777-3785 | |
| P577 | publication date | 2006-08-08 | |
| P1433 | published in | Blood | Q885070 |
| P1476 | title | Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells | |
| P478 | volume | 108 |
| Q47663392 | A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice |
| Q50214860 | A novel Foxn1eGFP/+ mouse model identifies Bmp4-induced maintenance of Foxn1 expression and thymic epithelial progenitor populations. |
| Q37543241 | A roadmap for thymic epithelial cell development. |
| Q33728091 | ADAM17 deletion in thymic epithelial cells alters aire expression without affecting T cell developmental progression |
| Q38773105 | AIRE expands: new roles in immune tolerance and beyond. |
| Q37089841 | Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span |
| Q33748998 | Administration of RANKL boosts thymic regeneration upon bone marrow transplantation |
| Q28083721 | Adult thymic epithelial cell (TEC) progenitors and TEC stem cells: Models and mechanisms for TEC development and maintenance |
| Q98718621 | Ageing compromises mouse thymus function and remodels epithelial cell differentiation |
| Q48333963 | Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus. |
| Q37181662 | Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation |
| Q55048314 | Architectural changes in the thymus of aging mice. |
| Q48636789 | Autoimmunity associated with chemically induced thymic dysplasia |
| Q50759869 | Bipotency of thymic epithelial progenitors comes in sequence. |
| Q41954318 | Border control: Anatomical origins of the thymus medulla |
| Q34198032 | CCL25 increases thymopoiesis after androgen withdrawal |
| Q38368929 | CD28-CD80/86 and CD40-CD40L Interactions Promote Thymic Tolerance by Regulating Medullary Epithelial Cell and Thymocyte Development |
| Q28504649 | Cbx4 regulates the proliferation of thymic epithelial cells and thymus function |
| Q26825505 | Changes in primary lymphoid organs with aging |
| Q37083552 | Characterization of the thymic IL-7 niche in vivo. |
| Q37045948 | Clinical strategies to enhance posttransplant immune reconstitution |
| Q86039503 | Conditioned deletion of ephrinB1 and/or ephrinB2 in either thymocytes or thymic epithelial cells alters the organization of thymic medulla and favors the appearance of thymic epithelial cysts |
| Q38453659 | Construction of a functional thymic microenvironment from pluripotent stem cells for the induction of central tolerance |
| Q92980515 | Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging |
| Q94452473 | Critical role of histone H3 lysine 27 demethylase Kdm6b in the homeostasis and function of medullary thymic epithelial cells |
| Q33531736 | DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration |
| Q45917614 | DL4-mediated Notch signaling is required for the development of fetal αβ and γδ T cells. |
| Q33348652 | Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution |
| Q37119813 | Deficient ghrelin receptor-mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity |
| Q36946535 | Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. |
| Q55513310 | Despite high levels of expression in thymic epithelial cells, miR-181a1 and miR-181b1 are not required for thymic development. |
| Q49179781 | Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus |
| Q38810880 | Development and developmental potential of cortical thymic epithelial cells |
| Q39207497 | Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla |
| Q87218659 | Disorganization of the splenic microanatomy in ageing mice |
| Q94521577 | Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells |
| Q90339687 | Dynamic changes in epithelial cell morphology control thymic organ size during atrophy and regeneration |
| Q36800015 | Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla |
| Q37792913 | Dysregulation of Thymic Clonal Deletion and the Escape of Autoreactive T Cells |
| Q36949091 | Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated |
| Q92643265 | Efficient generation of thymic epithelium from induced pluripotent stem cells that prolongs allograft survival |
| Q28536740 | Elevated levels of interferon-γ production by memory T cells do not promote transplant tolerance resistance in aged recipients |
| Q37939596 | Eph/Ephrin-mediated interactions in the thymus |
| Q54472119 | Eph/ephrinB signalling is involved in the survival of thymic epithelial cells. |
| Q35005451 | Established thymic epithelial progenitor/stem cell-like cell lines differentiate into mature thymic epithelial cells and support T cell development |
| Q24299031 | FGFR2IIIb signaling regulates thymic epithelial differentiation |
| Q26744673 | FOXN1 in thymus organogenesis and development |
| Q28755731 | Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner |
| Q28589335 | Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence |
| Q90428008 | Fundamental parameters of the developing thymic epithelium in the mouse |
| Q64880268 | Gender-Related Effect of Sodium Dichloroacetate on the Number of Hassall's Corpuscles and RNA NKCC1 Expression in Rat Thymus. |
| Q36997113 | Generating intrathymic microenvironments to establish T-cell tolerance. |
| Q39187317 | Generation of diversity in thymic epithelial cells. |
| Q41606459 | Genetic and non-genetic determinants of thymic epithelial cell number and function |
| Q38053490 | Genetic basis of altered central tolerance and autoimmune diseases: a lesson from AIRE mutations |
| Q35970878 | Ghrelin promotes thymopoiesis during aging |
| Q42780735 | Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution |
| Q38599476 | Hormonal control of T-cell development in health and disease |
| Q38038330 | ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs--threshold doses for tissue reactions in a radiation protection context |
| Q35744823 | Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells |
| Q36762777 | Identification of a Bipotent Epithelial Progenitor Population in the Adult Thymus. |
| Q27331912 | Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6 |
| Q24655433 | Immunosenescence: emerging challenges for an ageing population |
| Q48143719 | Improved expression of Sirt1 on thymic epithelial cells of SAMP10 after Intrabone marrow-bone marrow transplantation |
| Q41488790 | In vivo lineage tracing reveals Axin2-expressing, long-lived cortical thymic epithelial progenitors in the postnatal thymus |
| Q45491251 | Increased cFLIP expression in thymic epithelial tumors blocks autophagy via NF-κB signalling. |
| Q37317349 | Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution |
| Q37156773 | Inhibition of transplantation tolerance by immune senescence is reversed by endocrine modulation |
| Q27308759 | Interleukin-21 accelerates thymic recovery from glucocorticoïd-induced atrophy |
| Q36665434 | Interleukin-21 administration to aged mice rejuvenates their peripheral T-cell pool by triggering de novo thymopoiesis |
| Q24595764 | Interleukin-22 drives endogenous thymic regeneration in mice |
| Q33588677 | Is thymocyte development functional in the aged? |
| Q38264767 | Isolation of thymic epithelial cells and analysis by flow cytometry. |
| Q35804466 | Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells |
| Q36713565 | Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation |
| Q35067931 | Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus |
| Q37105558 | Leptin receptor is expressed in thymus medulla and leptin protects against thymic remodeling during endotoxemia-induced thymus involution |
| Q64052753 | Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance |
| Q37383866 | Luteinizing hormone-releasing hormone enhances T cell recovery following allogeneic bone marrow transplantation |
| Q37303952 | Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells |
| Q54958407 | Lymphotoxin α fine-tunes T cell clonal deletion by regulating thymic entry of antigen-presenting cells. |
| Q36948590 | Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells. |
| Q38810883 | Medullary thymic epithelial stem cells: role in thymic epithelial cell maintenance and thymic involution |
| Q53120646 | Mesenchymal stromal cells support the viability and differentiation of thymocytes through direct contact in autologous co-cultures. |
| Q36947118 | MicroRNA-195a-5p inhibits mouse medullary thymic epithelial cells proliferation by directly targeting Smad7 |
| Q36911011 | MicroRNAs control the maintenance of thymic epithelia and their competence for T lineage commitment and thymocyte selection |
| Q37400178 | Modeling the development of the post-natal mouse thymus in the absence of bone marrow progenitors |
| Q34916448 | Models of self-peptide sampling by developing T cells identify candidate mechanisms of thymic selection |
| Q28509341 | Modulation of Aire regulates the expression of tissue-restricted antigens |
| Q27011835 | Molecular control over thymic involution: from cytokines and microRNA to aging and adipose tissue |
| Q35925023 | Multiple prethymic defects underlie age-related loss of T progenitor competence |
| Q91619411 | Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth |
| Q41979732 | NF-κB in T-cell Acute Lymphoblastic Leukemia: Oncogenic Functions in Leukemic and in Microenvironmental Cells. |
| Q36062664 | Natural Th17 cells are critically regulated by functional medullary thymic microenvironments. |
| Q35585931 | Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells |
| Q92844503 | Physiology and pathology of T-cell aging |
| Q54164216 | Polycomb group gene Bmi1 plays a role in the growth of thymic epithelial cells. |
| Q33648539 | Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy |
| Q34170759 | Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells |
| Q36349284 | Premature thymic involution is independent of structural plasticity of the thymic stroma. |
| Q36229072 | Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire |
| Q34508579 | Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution |
| Q51972426 | Promiscuous gene expression and the developmental dynamics of medullary thymic epithelial cells. |
| Q89495155 | Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration |
| Q91794163 | Quantitative analysis reveals reciprocal regulations underlying recovery dynamics of thymocytes and thymic environment in mice |
| Q41868543 | RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla |
| Q37727277 | Regeneration of dendritic cells in aged mice |
| Q34414351 | Regeneration of the aged thymus by a single transcription factor. |
| Q35807736 | Regenerative capacity of adult cortical thymic epithelial cells |
| Q38132390 | Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases |
| Q33348553 | RelB-dependent stromal cells promote T-cell leukemogenesis |
| Q35898840 | Requirement of Stat3 Signaling in the Postnatal Development of Thymic Medullary Epithelial Cells |
| Q40574331 | Restoration of Thymus Function with Bioengineered Thymus Organoids |
| Q35238124 | RhoB deficiency in thymic medullary epithelium leads to early thymic atrophy |
| Q60489259 | Roles of the RANKL–RANK axis in antitumour immunity — implications for therapy |
| Q37223456 | Selected Toll-like receptor ligands and viruses promote helper-independent cytotoxic T cell priming by upregulating CD40L on dendritic cells |
| Q43809296 | Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input |
| Q35926133 | Sex hormones have pervasive effects on thymic epithelial cells. |
| Q37346211 | Sex steroid ablation: an immunoregenerative strategy for immunocompromised patients |
| Q37341029 | Single cell analysis of complex thymus stromal cell populations: rapid thymic epithelia preparation characterizes radiation injury |
| Q47734588 | Single-cell RNA-sequencing resolves self-antigen expression during mTEC development |
| Q35898874 | Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells. |
| Q27007013 | Stem cell treatment for Alzheimer's disease |
| Q62078525 | Stemming the tide of thymic aging |
| Q35750903 | Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging |
| Q30851570 | T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction |
| Q100958904 | T cell regeneration after immunological injury |
| Q37212717 | T-cell reconstitution after allogeneic stem cell transplantation: assessment by measurement of the sjTREC/βTREC ratio and thymic naive T cells |
| Q36787592 | TGF-beta signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution. |
| Q38042619 | TNF receptor family signaling in the development and functions of medullary thymic epithelial cells |
| Q28589031 | TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation |
| Q49834187 | Targeted deletion of c-Met in thymic epithelial cells leads to an autoimmune phenotype |
| Q28585690 | Tbata modulates thymic stromal cell proliferation and thymus function |
| Q34372619 | The Antigenic Determinant That Defines Thymic Nurse Cells Is Expressed by Thymic Epithelial Progenitor Cells |
| Q26795470 | The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the Thymus |
| Q28589207 | The Foxn1-dependent transcripts PCOLCE2 and mPPP1R16B are not required for normal thymopoiesis |
| Q37790917 | The Thymus and the Immune System: Layered Levels of Control |
| Q26849798 | The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein |
| Q21131204 | The effect of age on thymic function |
| Q38000156 | The immune system in the aging human |
| Q37313942 | The immunopathology of thymic GVHD. |
| Q37382924 | The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells |
| Q37991317 | The origin and implication of thymic involution |
| Q36955377 | The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis |
| Q37551442 | Theories and quantification of thymic selection |
| Q34020483 | Thiazolidinedione treatment and constitutive-PPARgamma activation induces ectopic adipogenesis and promotes age-related thymic involution |
| Q89820605 | Thymic Epithelial Cells Contribute to Thymopoiesis and T Cell Development |
| Q95272124 | Thymic Function Associated With Cancer Development, Relapse, and Antitumor Immunity - A Mini-Review |
| Q35083246 | Thymic T-cell development in allogeneic stem cell transplantation |
| Q40288414 | Thymic crosstalk restrains the pool of cortical thymic epithelial cells with progenitor properties |
| Q36474503 | Thymic epithelial requirement for γδ T cell development revealed in the cell ablation transgenic system with TSCOT promoter |
| Q33349488 | Thymic fatness and approaches to enhance thymopoietic fitness in aging |
| Q36085377 | Thymic gene transfer of myelin oligodendrocyte glycoprotein ameliorates the onset but not the progression of autoimmune demyelination |
| Q33729251 | Thymic homing of activated CD4+ T cells induces degeneration of the thymic epithelium through excessive RANK signaling |
| Q37361275 | Thymic involution and immune reconstitution. |
| Q37939600 | Thymic involution: where endocrinology meets immunology. |
| Q37360649 | Thymic microenvironments for T-cell repertoire formation |
| Q36483791 | Thymic nurse cells provide microenvironment for secondary T cell receptor α rearrangement in cortical thymocytes. |
| Q38716135 | Thymic stromal cell subsets for T cell development |
| Q49571906 | Thymic stromal cells: Roles in atrophy and age-associated dysfunction of the thymus |
| Q64935581 | Thymic tolerance as a key brake on autoimmunity. |
| Q34151895 | Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage |
| Q36031759 | Thymus Size and Age-related Thymic Involution: Early Programming, Sexual Dimorphism, Progenitors and Stroma |
| Q96163058 | Thymus aging in mice deficient in either EphB2 or EphB3, two master regulators of thymic epithelium development |
| Q37471102 | Thymus and aging: morphological, radiological, and functional overview |
| Q38139859 | Thymus involution and regeneration: two sides of the same coin? |
| Q36815662 | Thymus: the next (re)generation |
| Q37427754 | Tolerance has its limits: how the thymus copes with infection |
| Q33373129 | Tolerance to self: which cells kill? |
| Q24648384 | Transcriptional regulation by AIRE: molecular mechanisms of central tolerance |
| Q40779413 | Transcriptome sequencing of neonatal thymic epithelial cells |
| Q38530619 | Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system |
| Q50314118 | Twenty Years of AIRE. |
| Q99237795 | When the Damage Is Done: Injury and Repair in Thymus Function |
| Q35783525 | Young, proliferative thymic epithelial cells engraft and function in aging thymuses |
| Q35927028 | mTORC1 in Thymic Epithelial Cells Is Critical for Thymopoiesis, T-Cell Generation, and Temporal Control of γδT17 Development and TCRγ/δ Recombination |
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