scholarly article | Q13442814 |
P50 | author | Josef Penninger | Q1674391 |
Graham Anderson | Q56643596 | ||
Guillaume E Desanti | Q60656139 | ||
William E. Jenkinson | Q41592803 | ||
P2093 | author name string | Eric J Jenkinson | |
Andrea J White | |||
Jennifer E Cowan | |||
Sonia M Parnell | |||
Peter J L Lane | |||
Song Baik | |||
P2860 | cites work | New member of the winged-helix protein family disrupted in mouse and rat nude mutations | Q24308068 |
Regulation of CD8+ T cell development by thymus-specific proteasomes | Q28116400 | ||
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases | Q28131652 | ||
Projection of an immunological self shadow within the thymus by the aire protein | Q28207164 | ||
Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance | Q28585306 | ||
Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance | Q34112986 | ||
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells | Q34576335 | ||
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development | Q34577749 | ||
Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion | Q59066328 | ||
Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity | Q63190413 | ||
Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: evidence that receptor-bearing lymphocytes influence maturation of the thymic microenvironment | Q70212975 | ||
Checkpoints in the development of thymic cortical epithelial cells | Q83088896 | ||
The impact of cell re-entry into the primary lymphoid organs on lymphocyte repertoire and functionality | Q83158558 | ||
Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their development | Q34587142 | ||
The thymus as an inductive site for T lymphopoiesis | Q34628878 | ||
Humoral immune responses in CD40 ligand-deficient mice | Q34725239 | ||
Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit | Q34750367 | ||
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium | Q36011240 | ||
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen | Q36228141 | ||
Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire | Q36229072 | ||
Thymic emigration revisited | Q36229138 | ||
Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. | Q36371648 | ||
Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation | Q36399298 | ||
Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. | Q36399327 | ||
Journey through the thymus: stromal guides for T-cell development and selection | Q36402237 | ||
Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. | Q36946535 | ||
Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells | Q37303952 | ||
Control of central self-tolerance induction by autoreactive CD4+ thymocytes | Q37651855 | ||
Thymic epithelial cells: working class heroes for T cell development and repertoire selection | Q38010575 | ||
AIRE-induced apoptosis is associated with nuclear translocation of stress sensor protein GAPDH. | Q39345151 | ||
Preparation of 2-dGuo-treated thymus organ cultures. | Q40238298 | ||
Reaggregate thymus cultures. | Q40238464 | ||
Transfection and ligation of CD40 in human oral keratinocytes affect proliferation, adhesion and migration but not apoptosis in vitro | Q40314864 | ||
Thymus medulla consisting of epithelial islets each derived from a single progenitor | Q40763624 | ||
RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla | Q41868543 | ||
Delta-like 4 is indispensable in thymic environment specific for T cell development | Q42277361 | ||
CD40 ligation alters the cell cycle of differentiating keratinocytes | Q42484193 | ||
The thymic medulla: a unique microenvironment for intercellular self-antigen transfer | Q42572856 | ||
Growth of epithelial cells in the thymic medulla is under the control of mature T cells | Q42769057 | ||
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input | Q43809296 | ||
Regulation of RAG-1 and CD69 expression in the thymus during positive and negative selection | Q44072201 | ||
Thymus-specific serine protease regulates positive selection of a subset of CD4+ thymocytes | Q46089880 | ||
Continued maturation of thymic emigrants in the periphery | Q48022294 | ||
Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells. | Q50766532 | ||
The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. | Q51949099 | ||
Promiscuous gene expression and the developmental dynamics of medullary thymic epithelial cells. | Q51972426 | ||
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. | Q52010433 | ||
Thymic overexpression of CD40 ligand disrupts normal thymic epithelial organization. | Q52523664 | ||
Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis. | Q53174108 | ||
Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance. | Q53253030 | ||
The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. | Q53453365 | ||
Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma. | Q54380933 | ||
Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. | Q54558035 | ||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 5519-5526 | |
P577 | publication date | 2012-11-14 | |
P1433 | published in | Journal of Immunology | Q3521441 |
P1476 | title | Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla | |
P478 | volume | 189 |
Q89808480 | A cell atlas of human thymic development defines T cell repertoire formation |
Q27005894 | A review of denosumab for the treatment of osteoporosis |
Q47227251 | AIRE: a missing link to explain female susceptibility to autoimmune diseases. |
Q37627734 | An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells |
Q39367844 | Association between RANK, RANKL and OPG polymorphisms with ACPA and erosions in rheumatoid arthritis: results from a meta-analysis involving three French cohorts. |
Q38368929 | CD28-CD80/86 and CD40-CD40L Interactions Promote Thymic Tolerance by Regulating Medullary Epithelial Cell and Thymocyte Development |
Q86039503 | Conditioned deletion of ephrinB1 and/or ephrinB2 in either thymocytes or thymic epithelial cells alters the organization of thymic medulla and favors the appearance of thymic epithelial cysts |
Q26752793 | Control of the thymic medulla and its influence on αβT-cell development |
Q33965318 | Cutting edge: Antigen-specific thymocyte feedback regulates homeostatic thymic conventional dendritic cell maturation |
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Q38113210 | Immunology and bone |
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Q58582775 | Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups |
Q40646125 | Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development. |
Q36898545 | RANKL cytokine: from pioneer of the osteoimmunology era to cure for a rare disease |
Q53487298 | RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation. |
Q37387660 | Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance |
Q35926133 | Sex hormones have pervasive effects on thymic epithelial cells. |
Q36715524 | Sonic Hedgehog regulates thymic epithelial cell differentiation |
Q35898874 | Stat3 Signaling Promotes Survival And Maintenance Of Medullary Thymic Epithelial Cells. |
Q30851570 | T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction |
Q37421214 | TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development |
Q64102143 | The RANKL-RANK Axis: A Bone to Thymus Round Trip |
Q38367239 | The contribution of NF-κB signalling to immune regulation and tolerance |
Q26800152 | Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction |
Q37593760 | Thymic epithelial cell development and its dysfunction in human diseases. |
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