| P2093 | author name string | Leonie F A Huitema | |
| | Sander W Tas | |
| | Myrthe A M van Delft | |
| P2860 | cites work | RANK is essential for osteoclast and lymph node development | Q24598872 |
| | Generation and activation of multiple dimeric transcription factors within the NF-kappaB signaling system | Q24641914 |
| | Deletional tolerance mediated by extrathymic Aire-expressing cells | Q24652952 |
| | Coordination between NF-kappaB family members p50 and p52 is essential for mediating LTbetaR signals in the development and organization of secondary lymphoid tissues | Q24685416 |
| | Positional cloning of the APECED gene | Q28116470 |
| | Aire deficient mice develop multiple features of APECED phenotype and show altered immune response | Q28202432 |
| | Projection of an immunological self shadow within the thymus by the aire protein | Q28207164 |
| | The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation | Q28586300 |
| | Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells | Q28593219 |
| | Expression of relB is required for the development of thymic medulla and dendritic cells | Q28594949 |
| | Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see) | Q29391777 |
| | The two NF-kappaB activation pathways and their role in innate and adaptive immunity | Q29614355 |
| | Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance | Q33569842 |
| | Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells | Q33703633 |
| | RelB modulation of IkappaBalpha stability as a mechanism of transcription suppression of interleukin-1alpha (IL-1alpha), IL-1beta, and tumor necrosis factor alpha in fibroblasts | Q33960289 |
| | The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation | Q33977713 |
| | Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance | Q34112986 |
| | Control of central and peripheral tolerance by Aire | Q34177944 |
| | Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus | Q34247810 |
| | Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-kappa B/Rel family | Q34317095 |
| | Limitation of immune tolerance-inducing thymic epithelial cell development by Spi-B-mediated negative feedback regulation | Q34533105 |
| | Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells | Q34576335 |
| | Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their development | Q34587142 |
| | Dendritic cells in the thymus contribute to T-regulatory cell induction | Q34601754 |
| | Thymus-specific deletion of insulin induces autoimmune diabetes | Q34610806 |
| | Cell-intrinsic role for NF-kappa B-inducing kinase in peripheral maintenance but not thymic development of Foxp3+ regulatory T cells in mice | Q35000966 |
| | IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells. | Q35039306 |
| | NF-kappaB2 is required for the establishment of central tolerance through an Aire-dependent pathway | Q35070399 |
| | Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells | Q35992433 |
| | Chronic inflammation caused by lymphotoxin is lymphoid neogenesis | Q36366337 |
| | Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. | Q55032978 |
| | Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. | Q55035366 |
| | The cellular mechanism of Aire control of T cell tolerance. | Q55041159 |
| | Osteopetrosis rescue upon RANKL administration to Rankl(-/-) mice: a new therapy for human RANKL-dependent ARO. | Q55056509 |
| | Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self | Q57232929 |
| | IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation | Q59054264 |
| | Requirement for the NF-kappaB family member RelA in the development of secondary lymphoid organs | Q36369876 |
| | Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR. | Q36371648 |
| | Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture | Q36400143 |
| | Lymphoid organ development: from ontogeny to neogenesis | Q36426808 |
| | The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development | Q36750060 |
| | Aire-dependent thymic development of tumor-associated regulatory T cells | Q36754190 |
| | Transcriptional impact of Aire varies with cell type | Q36893646 |
| | Association of the AIRE gene with susceptibility to rheumatoid arthritis in a European population: a case control study | Q36903321 |
| | Critical immunological pathways are downregulated in APECED patient dendritic cells | Q37200594 |
| | The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells | Q37262669 |
| | Aire | Q37419376 |
| | TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development | Q37421214 |
| | Thymus microenvironment in human primary immunodeficiency diseases. | Q37617916 |
| | Noncanonical NF-κB signaling is limited by classical NF-κB activity | Q37651821 |
| | New insights into the development of lymphoid tissues | Q37779724 |
| | Non-canonical NF-κB signaling pathway | Q37822660 |
| | Tertiary lymphoid organs in infection and autoimmunity | Q38012568 |
| | Homeostatic control of regulatory T cell diversity. | Q38183674 |
| | Non-canonical NF-κB signaling in rheumatoid arthritis: Dr Jekyll and Mr Hyde? | Q38379658 |
| | Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla | Q39207497 |
| | Lymphotoxin pathway directs thymic Aire expression | Q40630236 |
| | Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase | Q40954925 |
| | RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla | Q41868543 |
| | CD40/CD40L interaction regulates CD4+CD25+ T reg homeostasis through dendritic cell-produced IL-2. | Q42473719 |
| | RelB forms transcriptionally inactive complexes with RelA/p65. | Q42803778 |
| | Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. | Q44338643 |
| | Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation | Q44638428 |
| | Regulation of naive T cell function by the NF-kappaB2 pathway | Q46071109 |
| | Human secondary lymphoid organs typically contain polyclonally-activated proliferating regulatory T cells | Q46183362 |
| | Autoimmune regulator controls T cell help for pathogenetic autoantibody production in collagen-induced arthritis | Q47697144 |
| | The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues | Q47713235 |
| | A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery | Q47865748 |
| | The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. | Q51949099 |
| | Mature T cells depend on signaling through the IKK complex. | Q52005562 |
| | I kappa B kinase complex alpha kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue. | Q52085932 |
| | NF-kappa B-inducing kinase establishes self-tolerance in a thymic stroma-dependent manner. | Q52093900 |
| | A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues. | Q52094509 |
| | Defective lymphotoxin-beta receptor-induced NF-kappaB transcriptional activity in NIK-deficient mice. | Q52542561 |
| | The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator. | Q53453365 |
| | Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation. | Q53555159 |
| | Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells. | Q53581481 |
| | NF-κB-inducing kinase in thymic stroma establishes central tolerance by orchestrating cross-talk with not only thymocytes but also dendritic cells. | Q54319219 |
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | NF-κB | Q411114 |
| P304 | page(s) | 529-539 | |
| P577 | publication date | 2015-05-01 | |
| P1433 | published in | European Journal of Clinical Investigation | Q15745208 |
| P1476 | title | The contribution of NF-κB signalling to immune regulation and tolerance | |
| P478 | volume | 45 | |