A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery

scientific article published in March 2008

A specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.180.6.3824
P698PubMed publication ID18322189
P5875ResearchGate publication ID5530549

P50authorWilliam R HeathQ41610442
P2093author name stringLi Wu
Hamish S Scott
Kylie E Webster
Sarah A Kinkel
Ping Cannon
Pauline E Crewther
François-Xavier Hubert
Anna I Proeitto
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
P304page(s)3824-3832
P577publication date2008-03-01
P1433published inJournal of ImmunologyQ3521441
P1476titleA specific anti-Aire antibody reveals aire expression is restricted to medullary thymic epithelial cells and not expressed in periphery
P478volume180

Reverse relations

cites work (P2860)
Q37543241A roadmap for thymic epithelial cell development.
Q37615692AIRE in the thymus and beyond
Q41445758AIRE is a critical spindle-associated protein in embryonic stem cells
Q43782327AIRE1A might be involved in cyclin B2 degradation in testicular lysates
Q35147048Abnormalities of thymic stroma may contribute to immune dysregulation in murine models of leaky severe combined immunodeficiency
Q43571237Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult
Q36296990Aire promotes the self-renewal of embryonic stem cells through Lin28.
Q92657238Aire-expressing ILC3-like cells in the lymph node display potent APC features
Q37181662Alterations of the medullary epithelial compartment in the Aire-deficient thymus: implications for programs of thymic epithelial differentiation
Q41619568Altered Immune Activation and IL-23 Signaling in Response to Candida albicans in Autoimmune Polyendocrine Syndrome Type 1
Q48918741Association of AIRE polymorphisms with genetic susceptibility to rheumatoid arthritis in a Chinese population
Q21296658Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy: insights into genotype-phenotype correlation
Q47697144Autoimmune regulator controls T cell help for pathogenetic autoantibody production in collagen-induced arthritis
Q28512316Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes
Q36861631B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: A therapeutic approach for APECED patients.
Q34600502Central tolerance: what have we learned from mice?
Q34177944Control of central and peripheral tolerance by Aire
Q26752793Control of the thymic medulla and its influence on αβT-cell development
Q33869784DNMT3L is a regulator of X chromosome compaction and post-meiotic gene transcription
Q24652952Deletional tolerance mediated by extrathymic Aire-expressing cells
Q54452411Diversity and clonotypic composition of influenza-specific CD8+ TCR repertoires remain unaltered in the absence of Aire.
Q37837965Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue
Q21296698Expression of the autoimmune regulator gene and its relevance to the mechanisms of central and peripheral tolerance
Q28593219Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells
Q90428008Fundamental parameters of the developing thymic epithelium in the mouse
Q33703633Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells
Q34122665Hypomorphic Rag mutations can cause destructive midline granulomatous disease
Q36341342Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus
Q38264767Isolation of thymic epithelial cells and analysis by flow cytometry.
Q37453563Learning to be tolerant: how T cells keep out of trouble
Q33794995Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
Q61448759Maturing Human CD127+ CCR7+ PDL1+ Dendritic Cells Express AIRE in the Absence of Tissue Restricted Antigens
Q38810883Medullary thymic epithelial stem cells: role in thymic epithelial cell maintenance and thymic involution
Q51942374Metallophilic macrophages are fully developed in the thymus of autoimmune regulator (Aire)-deficient mice.
Q47442891Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen
Q38008330Models of aire-dependent gene regulation for thymic negative selection.
Q62230249NKT cell development in the absence of the autoimmune regulator gene (Aire)
Q35861549Plasmacytoid dendritic cells transport peripheral antigens to the thymus to promote central tolerance
Q21131226Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens
Q38132390Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases
Q82949789Self-encounters of the third kind: lymph node stroma promotes tolerance to peripheral tissue antigens
Q36006790Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression
Q37421214TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development
Q34980159TSLP expression: analysis with a ZsGreen TSLP reporter mouse
Q38367239The contribution of NF-κB signalling to immune regulation and tolerance
Q34601204The impact of circulating dendritic cells on the development and differentiation of thymocytes
Q37348444The thymus medulla slowly yields its secrets.
Q50282373Thymic Dendritic Cell Subsets Display Distinct Efficiencies and Mechanisms of Intercellular MHC Transfer
Q36719265Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN.
Q37501186Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways
Q90498144Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms
Q34163776Transcriptional and histological analyses of the thymic developmental process in the fetal pig
Q24648384Transcriptional regulation by AIRE: molecular mechanisms of central tolerance
Q39627505Transplantation of autoimmune regulator-encoding bone marrow cells delays the onset of experimental autoimmune encephalomyelitis
Q84501376Ultrastructure of medullary thymic epithelial cells of autoimmune regulator (Aire)-deficient mice
Q47856335Update on Aire and thymic negative selection
Q33849740Why Aire? Compensating for late bloomers

Search more.